Tetrandrine induces apoptosis and triggers caspase cascade in human bladder cancer cells

Journal of Surgical Research

Volumn 166, Issue 1, 2011, Pages

  Li, Xudong ^a   Su, Bin ^b   Liu, Runming ^a   Wu, Dapeng ^a   He, Dalin ^a  

^a XI'AN JIAOTONG UNIVERSITY   (China)

^b SOUTHERN MEDICAL UNIVERSITY   (China)

Author keywords

apoptosis; bladder cancer; caspase; mitochondria; tetrandrine

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; C38H42O6N2; CASPASE 3; CASPASE 8; CASPASE 9; CYTOCHROME C; TETRANDRINE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; BLADDER CANCER; CANCER CELL; CANCER INHIBITION; CELL ASSAY; CELLULAR DISTRIBUTION; COLORIMETRY; CONTROLLED STUDY; CYTOSOL; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VIVO STUDY; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; PRIORITY JOURNAL; REACTOR CASCADE; WESTERN BLOTTING;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BENZYLISOQUINOLINES; CARCINOMA, TRANSITIONAL CELL; CASPASES; CELL DIVISION; CELL LINE, TUMOR; HUMANS; MITOCHONDRIA; URINARY BLADDER NEOPLASMS;

EID: 79951680794     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2010.10.034     Document Type: Article

References (28)

1. A. Jemal, R. Siegel, and J. Xu Cancer statistics, 2010 CA Cancer J Clin 60 2010 277
2. D.S. Kaufman, W.U. Shipley, and A.S. Feldman Bladder cancer Lancet 374 2009 239
3. Z. Shen, T. Shen, and M.G. Wientjes Intravesical treatments of bladder cancer: Review Pharm Res 25 2008 1500
4. P.U. Malmstrom Intravesical therapy of superficial bladder cancer Crit Rev Oncol Hematol 47 2003 109
5. Y.J. Chen Potential role of tetrandrine in cancer therapy Acta Pharmacol Sin 23 2002 1102
6. Y.L. Lai, Y.J. Chen, and T.Y. Wu Induction of apoptosis in human leukemic U937 cells by tetrandrine Anticancer Drugs 9 1998 77
7. L.T. Ng, L.C. Chiang, and Y.T. Lin Antiproliferative and apoptotic effects of tetrandrine on different human hepatoma cell lines Am J Chin Med 34 2006 125
8. J.M. Wu, Y. Chen, and J.C. Chen Tetrandrine induces apoptosis and growth suppression of colon cancer cells in mice Cancer Lett 287 2010 187
9. P.L. Kuo, and C.C. Lin Tetrandrine-induced cell cycle arrest and apoptosis in Hep G2 cells Life Sci 73 2003 243
10. L.H. Meng, H. Zhang, and L. Hayward Tetrandrine induces early G1 arrest in human colon carcinoma cells by down-regulating the activity and inducing the degradation of G1-S-specific cyclin-dependent kinases and by inducing p53 and p21Cip1 Cancer Res 64 2004 9086
11. H.S. Cho, S.H. Chang, and Y.S. Chung Synergistic effect of ERK inhibition on tetrandrine-induced apoptosis in A549 human lung carcinoma cells J Vet Sci 10 2009 23
12. J.H. Lee, G.H. Kang, and K.C. Kim Tetrandrine-induced cell cycle arrest and apoptosis in A549 human lung carcinoma cells Int J Oncol 21 2002 1239
13. Y. Chen, J.C. Chen, and S.H. Tseng Tetrandrine suppresses tumor growth and angiogenesis of gliomas in rats Int J Cancer 124 2009 2260
14. X. Sun, R. Xu, and Y. Deng Effects of tetrandrine on apoptosis and radiosensitivity of nasopharyngeal carcinoma cell line CNE Acta Biochim Biophys Sin (Shanghai) 39 2007 869
15. X.L. Chen, K.H. Ren, and H.W. He Involvement of PI3K/AKT/GSK3beta pathway in tetrandrine-induced G1 arrest and apoptosis Cancer Biol Ther 7 2008 1073
16. A.R. Santiago, A.J. Cristovao, and P.F. Santos High glucose induces caspase-independent cell death in retinal neural cells Neurobiol Dis 25 2007 464
17. N.A. Thornberry, and Y. Lazebnik Caspases: Enemies within Science 281 1998 1312
18. I.M. Ghobrial, T.E. Witzig, and A.A. Adjei Targeting apoptosis pathways in cancer therapy CA Cancer J Clin 55 2005 178
19. O. Micheau, M. Thome, and P. Schneider The long form of FLIP is an activator of caspase-8 at the Fas death-inducing signaling complex J Biol Chem 277 2002 45162
20. G. Kroemer, and J.C. Reed Mitochondrial control of cell death Nat Med 6 2000 513
21. N. Hail Jr. Mitochondria: A novel target for the chemoprevention of cancer Apoptosis 10 2005 687
22. E.C. Ledgerwood, and I.M. Morison Targeting the apoptosome for cancer therapy Clin Cancer Res 15 2009 420
23. A.M. Kamat Chemoprevention of superficial bladder cancer Expert Rev Anticancer Ther 3 2003 799
24. B.B. Aggarwal, and S. Shishodia Molecular targets of dietary agents for prevention and therapy of cancer Biochem Pharmacol 71 2006 1397
25. C. Wang, and R.J. Youle The role of mitochondria in apoptosis Annu Rev Genet 43 2009 95
26. X. Luo, I. Budihardjo, and H. Zou Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors Cell 94 1998 481
27. S.A. Susin, E. Daugas, and L. Ravagnan Two distinct pathways leading to nuclear apoptosis J Exp Med 192 2000 571
28. L. Li, J. Zeng, and Y. Gao Targeting silibinin in the antiproliferative pathway Expert Opin Investig Drugs 19 2010 243