DPA n-3, DPA n-6 and DHA improve lipoprotein profiles and aortic function in hamsters fed a high cholesterol diet

Atherosclerosis

Volumn 221, Issue 2, 2012, Pages 397-404

  Chen, Jingnan ^a   Jiang, Yue ^a   Liang, Yintong ^b   Tian, Xiaoyu ^b   Peng, Cheng ^b   Ma, Ka Ying ^b   Liu, Jian ^b   Huang, Yu ^b   Chen, Zhen Yu ^b  

^a HONG KONG BAPTIST UNIVERSITY   (Hong Kong)

^b CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Docosahexaenoic acid; Docosapentaenoic acid; HMG CoA reductase; SREBP 2; Total cholesterol; Vascular reactivity

Indexed keywords

4,7,10,13,16 DOCOSAPENTAENOIC ACID; 7,10,13,16,19 DOCOSAPENTAENOIC ACID; CHOLESTEROL; CYCLOOXYGENASE 2; DOCOSAPENTAENOIC ACID; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; LIPOPROTEIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; STEARIC ACID; STEROL REGULATORY ELEMENT BINDING PROTEIN 2; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AORTA; AORTA FUNCTION; AORTA RELAXATION; AORTA WALL TENSION; ARTERY CONSTRICTION; ARTICLE; CHOLESTEROL BILE LEVEL; CHOLESTEROL DIET; CORONARY ARTERY PRESSURE; DOWN REGULATION; GENE EXPRESSION REGULATION; HAMSTER; NONHUMAN; PRIORITY JOURNAL;

EID: 84862789548     PISSN: 00219150     EISSN: 18791484     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2012.01.005     Document Type: Article

References (38)

1. Holub B.J. Docosahexaenoic acid (DHA) and cardiovascular disease risk factors. Prostaglandins Leukot Essent Fatty Acids 2009, 81(2-3):199-204.
2. Chen J., Jiang Y., Ma K.Y., Chen F., Chen Z.Y. Microalga decreases plasma cholesterol by down-regulation of intestinal NPC1L1, hepatic LDL receptor, and HMG-CoA reductase. J Agric Food Chem 2011, 59(12):6790-6797.
3. Steinberg H.O., Bayazeed B., Hook G., et al. Endothelial dysfunction is associated with cholesterol levels in the high normal range in humans. Circulation 1997, 9:3287-3293.
4. Ng C.H., Yao X., Huang Y., Chen Z.Y. Oxidized cholesterol is more hypercholesterolemic and atherogenic than non-oxidized cholesterol in hamster. Br J Nutr 2008, 99:749-755.
5. Kasbi C.F., Andre A., Prieur X., et al. n-3 PUFA prevent metabolic disturbances associated with obesity and improve endothelial function in golden Syrian hamsters fed with a high-fat diet. Br J Nutr 2011, [Epub ahead of print]. 10.1017/S0007114511004387.
6. Liang Y.T., Wong W.T., Guan L., et al. Effect of phytosterols and their oxidation products on lipoprotein profiles and vascular function in hamster fed a high cholesterol diet. Atherosclerosis 2011, 219:124-133.
7. Ma K.Y., Yang N., Jiao R., et al. Dietary calcium decreases plasma cholesterol by down-regulation of intestinal NPC1L1 and MTP and up-regulation of CYP7A1 and ABCG 5/8 in hamsters. Mol Nutr Food Res 2011, 55:247-258.
8. Lam C.K., Chen J., Cao Y., et al. Conjugated and non-conjugated octadecaenoic acids affect differently intestinal acyl coenzyme A: cholesterol acyltransferase activity. Atherosclerosis 2008, 198:85-93.
9. Chan P.T., Fong W.P., Cheung Y.L., et al. Jasmine green epicatechins are hypolipidemic in hamsters fed a high fat diet. J Nutr 1999, 129:1094-1101.
10. Vaziri N.D., Liang K.H. Down-regulation of hepatic LDL receptor expression in experimental nephrosis. Kidney Int 1996, 50:887-893.
11. Alasek M.A.J., Repa J.J., Quan G., Dietschy J.M., Turley S.D. Inhibiting intestinal NPC1L1 activity prevents diet-induced increase in biliary cholesterol in Golden Syrian hamsters. Am J Physiol-Gastrointest Liver Physiol 2008, 295:813-822.
12. Field F.J., Born E., Mathur S.N. Stanol esters decrease plasma cholesterol independently of intestinal ABC sterol transporters and Niemann-Pick C1-like 1 protein gene expression. J Lipid Res 2004, 45:2252-2259.
13. Qin B., Qiu W., Avramoglu R.K., Adeli K. Tumor necrosis factor-alpha induces intestinal insulin resistance and stimulates the overproduction of intestinal apolipoprotein B48-containing lipoproteins. Diabetes 2007, 56:450-461.
14. Liang Y.T., Wong W.T., Guan L., et al. Effect of phytosterol and their oxidation products on lipoprotein profile and vascular function in hamster fed a high cholesterol diet. Atherosclerosis 2011, 219:124-133.
15. Wong S.L., Leung F.P., Lau C.W., et al. Cyclooxygenase-2-derived prostaglandin F2alpha mediates endothelium-dependent contractions in the aortae of hamsters with increased impact during aging. Circ Res 2009, 30:228-325.
16. Arteaga A., Villanueva C.L., Skorin C., et al. Dyslipidemic patients with coronary cardiopathy. Effect of different doses of omega-3 fatty acids on serum lipids and lipoprotein. Revista Medica De Chile 1993, 121:618-625.
17. Wu W.H., Lu S.C., Wang T.F., Jou H.J., Wang T.A. Effect of docosahexaenoic acid supplementation on blood lipids, estrogen metabolism, and in vivo oxidative stress in postmenopausal vegetarian women. Eur J Clin Nutr 2006, 60(3):386-392.
18. Julia G., Verónica K., Hans D., Berthold K. Microalgal docosahexaenoic acid decreases plasma triacylglycerol in normolipidaemic vegetarians: a randomised trial. Br J Nutr 2006, 95(4):779-786.
19. Theobald H.E., Chowienczyk P.J., Whittall R., Humphries S.E., Sanders T.A.B. LDL-cholesterol0-raising effect of low-dose docosahexaenoic acid in middle-age men and women. Am J Clin Nutr 2004, 79(4):558-563.
20. Sagara M., Njelekela M., Teramoto T., et al. Effect of docosaheaenoic acid supplementation on blood pressure, heart rate, and serum lipids in Scottish men wit hypertension and hypercholesterolemia. Int J Hypertens 2011, 10.4061/2011/809198.
21. Nelson G.J., Schmidt P.C., Bartolini G.L., Kelley D.S., Kyle D. The effect of dietary docosaxaenoic acid on plasma lipoproteins and tissue fatty acid composition in humans. Lipids 1997, 32(11):1137-1146.
22. Adan Y., Shibata K., Sato M., Ikeda I., Imaizumi K. Effect of docosahexaenoic and eicosapentaenoic acid on lipid metabolism, eicosanoid production, platelet aggregation and atherosclerosis in hypercholesterolemic rats. Biosci Biotech Biochem 1999, 63(1):111-119.
23. Umemura K., Toshima Y., Asai F., Nakashima M. Effect of dietary docosahexaenoic acid in rat middle cerebral artery thrombosis model. Thromb Res 1995, 78(5):379-387.
24. Carmen G.P.M., Eduardo G.-P., Marina M.C. Modification of phospholipids fatty acid composition in Reuber H35 hepatoma cells: effect on HMG-CoA reductase. J Cell Biochem 2003, 90(3):586-591.
25. Lindsey D., Pronczuk A., Hayes K.C. Low density lipoprotein from humans supplemented with n-3 fatty acids depresses both LDL receptor activity and LDLr mRNA in HepG2 cell. J Lipid Res 1992, 33(5):647-658.
26. Dawson K., Zhao L., Adkins Y., et al. Modulation of blood cell gene expression by DHA supplementation in hypertriglyceridemic men. J Nutr Biochem 2011, 10.1016/j.jnutbio2011.03.004.
27. Kaur G., Sinclair A.J., Cameron-Smith D., et al. Prostaglandins Leukt Essent Fatty Acids 2011, 85(3-4):155-161.
28. Alvaro A., Rosales R., Masana L., Vallve J.C. Polyunsaturated fatty acids down-regulate in vitro expresión of the key intestinal colesterol absorption protein NPC1L1: no effect of monounsaturated nor saturated fatty acids. J Nutr Biochem 2010, 21(6):518-525.
29. Mathur S.N., Watt K.R., Field F.J. Regulation of intestinal NPC1L1 expression by dietary fish oil and docosahexaenoic acid. J Lipid Res 2007, 48(2):395-404.
30. Engler M.B., Engler M.M. Docosahexaenoic acid-induced vasorelexation in hypertensive rats: mechanisms of action. Biol Res Nurs 2000, 2(2):85-95.
31. Engler M.B. Effect of omega-3 fatty acids, docosahexaenoic acid and eicosapentaenoic, on norepinephrine-induced contraction. Can J Physiol Pharmacol 1992, 70(5):675-679.
32. Locas A., Grynberg A., Lacour B., Goirand F. Dietary n-3 polyunsaturated fatty acids and endothelium dysfunction induced by lysophosphatidylcholine in Syrian hamster aorta. Metabolism-Clin Exp 2008, 57(2):233-240.
33. Goirand F., Ovide-Bordeaux S., Renaud J.F., Gryberg A., Lacour B. Effect of dietary docosahexaenoic acid on the endothelium-dependent vasorelaxation in diabetic rats. Clin Exp Pharmacol Physiol 2005, 32(3):184-190.
34. Widlansky M.E., Price D.T., Gokce N., et al. Short- and long-term COX-2 inhibition reverses endothelial dysfunction in patients with hypertension. Hypertension 2003, 42:310-315.
35. Cosentino F., Eto M., De Paolis P., et al. High glucose causes upregulation of cyclooxygenase-2 and alters prostanoid profile in human endothelial cells: role of protein kinase C and reactive oxygen species. Circulation 2003, 107:1017-1023.
36. Bagi Z., Erdei N., Toth A., et al. Type 2 diabetic mice have increased arteriolar tone and blood pressure: enhanced release of COX-2-derived constrictor prostaglandins. Arterioscler Thromb Vasc Biol 2005, 25:1610-1616.
37. Wong W.T., Tian X.Y., Chen Y., et al. Bone morphogenic protein-4 impairs endothelial function through oxidative stress-dependent cyclooxygenase-2 upregulation: implications on hypertension. Circ Res 2010, 107:984-991.
38. Burleigh M.E., Babaev V.R., Yancey P.G., et al. Cyclooxygenase-2 promotes early atherosclerotic lesion formation in ApoE-deficient and C57BL/6 mice. J Mol Cell Cardiol 2005, 39:443-452.