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Volumn 95, Issue 4, 2006, Pages 779-786

Microalgal docosahexaenoic acid decreases plasma triacylglycerol in normolipidaemic vegetarians: A randomised trial

Author keywords

Docosahexaenoic acid; Microalgae oil; Plasma lipids; Triacylglycerol

Indexed keywords

DOCOSAHEXAENOIC ACID; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; ICOSAPENTAENOIC ACID; LIPID; LONG CHAIN FATTY ACID; LOW DENSITY LIPOPROTEIN CHOLESTEROL; OLIVE OIL; OMEGA 3 FATTY ACID; PLACEBO; POLYUNSATURATED FATTY ACID; TRIACYLGLYCEROL;

EID: 33646456779     PISSN: 00071145     EISSN: 14752662     Source Type: Journal    
DOI: 10.1079/BJN20051720     Document Type: Article
Times cited : (75)

References (42)
  • 1
    • 0025189674 scopus 로고
    • Effect of fish oil on lipoproteins, lecithin: Cholesterol acyltransferase, and lipid transfer protein activity in humans
    • Abbey M, Clifton P, Kestin M, Belling B & Nestel P (1990) Effect of fish oil on lipoproteins, lecithin:cholesterol acyltransferase, and lipid transfer protein activity in humans. Arteriosclerosis 10, 85-94.
    • (1990) Arteriosclerosis , vol.10 , pp. 85-94
    • Abbey, M.1    Clifton, P.2    Kestin, M.3    Belling, B.4    Nestel, P.5
  • 4
    • 0025308724 scopus 로고
    • Effect of eicosapentaenoic and docosahexaenoic acids on blood pressure in hypertension. A population-based intervention trial from the Tromso study
    • Bonaa KH, Bjerve KS, Straume B, Gram IT & Thelle D (1990) Effect of eicosapentaenoic and docosahexaenoic acids on blood pressure in hypertension. A population-based intervention trial from the Tromso study. N Engl J Med 322, 795-801.
    • (1990) N Engl J Med , vol.322 , pp. 795-801
    • Bonaa, K.H.1    Bjerve, K.S.2    Straume, B.3    Gram, I.T.4    Thelle, D.5
  • 5
    • 6944255823 scopus 로고    scopus 로고
    • Circulating triacylglycerol and apoE levels in response to EPA and docosahexaenoic acid supplementation in adult human subjects
    • Buckley R, Shewring B, Turner R, Yaqoob P & Minihane AM (2004) Circulating triacylglycerol and apoE levels in response to EPA and docosahexaenoic acid supplementation in adult human subjects. Br J Nutr 92, 477-483.
    • (2004) Br J Nutr , vol.92 , pp. 477-483
    • Buckley, R.1    Shewring, B.2    Turner, R.3    Yaqoob, P.4    Minihane, A.M.5
  • 6
    • 0030469761 scopus 로고    scopus 로고
    • Supplementation with an algae source of docosahexaenoic acid increases (n-3) fatty acid status and alters selected risk factors for heart disease in vegetarian subjects
    • Conquer JA & Holub BJ (1996) Supplementation with an algae source of docosahexaenoic acid increases (n-3) fatty acid status and alters selected risk factors for heart disease in vegetarian subjects. J Nutr 126, 3032-3039.
    • (1996) J Nutr , vol.126 , pp. 3032-3039
    • Conquer, J.A.1    Holub, B.J.2
  • 7
    • 0031937621 scopus 로고    scopus 로고
    • Effect of supplementation with different doses of DHA on the levels of circulating DHA as non-esterified fatty acid in subjects of Asian Indian background
    • Conquer JA & Holub BJ (1998) Effect of supplementation with different doses of DHA on the levels of circulating DHA as non-esterified fatty acid in subjects of Asian Indian background. J Lipid Res 39, 286-292.
    • (1998) J Lipid Res , vol.39 , pp. 286-292
    • Conquer, J.A.1    Holub, B.J.2
  • 8
    • 0031000402 scopus 로고    scopus 로고
    • Effects of docosahexaenoic acid on serum lipoproteins in patients with combined hyperlipidemia: A randomized, double-blind, placebo-controlled trial
    • Davidson MH, Maki KC, Kalkowski J, Schaefer EJ, Torri SA & Drennan KB (1997) Effects of docosahexaenoic acid on serum lipoproteins in patients with combined hyperlipidemia: a randomized, double-blind, placebo-controlled trial. J Am Coll Nutr 16, 236-243.
    • (1997) J Am Coll Nutr , vol.16 , pp. 236-243
    • Davidson, M.H.1    Maki, K.C.2    Kalkowski, J.3    Schaefer, E.J.4    Torri, S.A.5    Drennan, K.B.6
  • 9
    • 0031936546 scopus 로고    scopus 로고
    • Apolipoprotein B metabolism in hypertriglyceridemic diabetic patients administered either a fish oil- or vegetable oil-enriched diet
    • Fisher WR, Zech LA & Stacpoole PW (1998) Apolipoprotein B metabolism in hypertriglyceridemic diabetic patients administered either a fish oil- or vegetable oil-enriched diet. J Lipid Res 39, 388-401.
    • (1998) J Lipid Res , vol.39 , pp. 388-401
    • Fisher, W.R.1    Zech, L.A.2    Stacpoole, P.W.3
  • 10
    • 0015348189 scopus 로고
    • Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge
    • Friedewald WT, Levy RI & Fredrickson DS (1972) Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 18, 499-502.
    • (1972) Clin Chem , vol.18 , pp. 499-502
    • Friedewald, W.T.1    Levy, R.I.2    Fredrickson, D.S.3
  • 12
    • 25844502497 scopus 로고    scopus 로고
    • Docosahexa enoic acid supplementation in vegetarians effectively increases omega-3 index: A randomized trial
    • Geppert J, Kraft V, Demmelmair H & Koletzko B (2005) Docosahexa enoic acid supplementation in vegetarians effectively increases omega-3 index: a randomized trial. Lipids 40, 870-814.
    • (2005) Lipids , vol.40 , pp. 814-870
    • Geppert, J.1    Kraft, V.2    Demmelmair, H.3    Koletzko, B.4
  • 13
    • 0035698484 scopus 로고    scopus 로고
    • The effect of n-3 fatty acids on low density lipoprotein subfractions
    • Griffin BA (2001) The effect of n-3 fatty acids on low density lipoprotein subfractions. Lipids 36, S91-S97.
    • (2001) Lipids , vol.36
    • Griffin, B.A.1
  • 14
    • 0031801260 scopus 로고    scopus 로고
    • Effects of highly purified eicosapentaenoic acid and docosahexaenoic acid on hemodynamics in humans
    • Grimsgaard S, Bonaa KH, Hansen JB & Myhre ES (1998) Effects of highly purified eicosapentaenoic acid and docosahexaenoic acid on hemodynamics in humans. Am J Clin Nutr 68, 52-59.
    • (1998) Am J Clin Nutr , vol.68 , pp. 52-59
    • Grimsgaard, S.1    Bonaa, K.H.2    Hansen, J.B.3    Myhre, E.S.4
  • 15
    • 0030763797 scopus 로고    scopus 로고
    • Highly purified eicosapentaenoic acid and docosahexaenoic acid in humans have similar triacylglycerol-lowering effects but divergent effects on serum fatty acids
    • Grimsgaard S, Bonaa KH, Hansen JB & Nordoy A (1997) Highly purified eicosapentaenoic acid and docosahexaenoic acid in humans have similar triacylglycerol-lowering effects but divergent effects on serum fatty acids. Am J Clin Nutr 66, 649-659.
    • (1997) Am J Clin Nutr , vol.66 , pp. 649-659
    • Grimsgaard, S.1    Bonaa, K.H.2    Hansen, J.B.3    Nordoy, A.4
  • 16
    • 0029157354 scopus 로고
    • Identifying adults at increased risk of coronary disease. How well do the current cholesterol guidelines work?
    • Grover SA, Coupal L & Hu XP (1995) Identifying adults at increased risk of coronary disease. How well do the current cholesterol guidelines work? JAMA 274, 801-806.
    • (1995) JAMA , vol.274 , pp. 801-806
    • Grover, S.A.1    Coupal, L.2    Hu, X.P.3
  • 17
    • 0028213190 scopus 로고
    • Serum lipid screening to identify high-risk individuals for coronary death. The results of the Lipid Research Clinics prevalence cohort
    • Grover SA, Palmer CS & Coupal L (1994) Serum lipid screening to identify high-risk individuals for coronary death. The results of the Lipid Research Clinics prevalence cohort. Arch Intern Med 154, 679-684.
    • (1994) Arch Intern Med , vol.154 , pp. 679-684
    • Grover, S.A.1    Palmer, C.S.2    Coupal, L.3
  • 18
    • 0030974010 scopus 로고    scopus 로고
    • N-3 fatty acids and serum lipoproteins: Human studies
    • Harris WS (1997) N-3 fatty acids and serum lipoproteins: human studies. Am J Clin Nutr 65, 1645S-1654S.
    • (1997) Am J Clin Nutr , vol.65
    • Harris, W.S.1
  • 19
    • 0026289265 scopus 로고
    • Simultaneous determination of retinol, tocopherols, carotenes and lycopene in plasma by means of high-performance liquid chromatography on reversed phase
    • Hess D, Keller HE, Oberlin B, Bonfanti R & Schuep W (1991) Simultaneous determination of retinol, tocopherols, carotenes and lycopene in plasma by means of high-performance liquid chromatography on reversed phase. Int J Vit Nutr Res 61, 232-238.
    • (1991) Int J Vit Nutr Res , vol.61 , pp. 232-238
    • Hess, D.1    Keller, H.E.2    Oberlin, B.3    Bonfanti, R.4    Schuep, W.5
  • 20
    • 0033535973 scopus 로고    scopus 로고
    • Triglyceride-rich lipoprotein remnant particles and risk of atherosclerosis
    • Hodis HN (1999) Triglyceride-rich lipoprotein remnant particles and risk of atherosclerosis. Circulation 99, 2852-2854.
    • (1999) Circulation , vol.99 , pp. 2852-2854
    • Hodis, H.N.1
  • 21
    • 0029838433 scopus 로고    scopus 로고
    • Plasma triglyceride level is a risk factor for cardiovascular disease independent of high-density lipoprotein cholesterol level: A meta-analysis of population-based prospective studies
    • Hokanson JE & Austin MA (1996) Plasma triglyceride level is a risk factor for cardiovascular disease independent of high-density lipoprotein cholesterol level: a meta-analysis of population-based prospective studies. J Cardiovasc Risk 3, 213-219.
    • (1996) J Cardiovasc Risk , vol.3 , pp. 213-219
    • Hokanson, J.E.1    Austin, M.A.2
  • 22
    • 0021365989 scopus 로고
    • Inhibition of low density lipoprotein synthesis by dietary omega-3 fatty acids in humans
    • Illingworth DR, Harris WS & Connor WE (1984) Inhibition of low density lipoprotein synthesis by dietary omega-3 fatty acids in humans. Arteriosclerosis 4, 270-275.
    • (1984) Arteriosclerosis , vol.4 , pp. 270-275
    • Illingworth, D.R.1    Harris, W.S.2    Connor, W.E.3
  • 23
    • 0025373171 scopus 로고
    • Changes in lipoprotein composition in hypertriglyceridemic patients taking cholesterol-free fish oil supplements
    • Inagaki M & Harris WS (1990) Changes in lipoprotein composition in hypertriglyceridemic patients taking cholesterol-free fish oil supplements. Atherosclerosis 82, 237-246.
    • (1990) Atherosclerosis , vol.82 , pp. 237-246
    • Inagaki, M.1    Harris, W.S.2
  • 24
    • 0028572530 scopus 로고
    • Cholesterol and coronary heart disease: Predicting risks by levels and ratios
    • Kinosian B, Glick H & Garland G (1994) Cholesterol and coronary heart disease: predicting risks by levels and ratios. Ann Intern Med 121, 641-647.
    • (1994) Ann Intern Med , vol.121 , pp. 641-647
    • Kinosian, B.1    Glick, H.2    Garland, G.3
  • 25
    • 0029383717 scopus 로고
    • Cholesterol and coronary heart disease: Predicting risks in men by changes in levels and ratios
    • Kinosian B, Glick H, Preiss L & Puder KL (1995) Cholesterol and coronary heart disease: predicting risks in men by changes in levels and ratios. J Invest Med 43, 443-450.
    • (1995) J Invest Med , vol.43 , pp. 443-450
    • Kinosian, B.1    Glick, H.2    Preiss, L.3    Puder, K.L.4
  • 26
    • 0024582271 scopus 로고
    • The antihypertensive effects of fish oil. A controlled study of polyunsaturated fatty acid supplements in essential hypertension
    • Knapp HR & FitzGerald GA (1989) The antihypertensive effects of fish oil. A controlled study of polyunsaturated fatty acid supplements in essential hypertension. N Engl J Med 320, 1037-1043.
    • (1989) N Engl J Med , vol.320 , pp. 1037-1043
    • Knapp, H.R.1    FitzGerald, G.A.2
  • 28
    • 0026638791 scopus 로고
    • Low density lipoprotein from humans supplemented with n-3 fatty acids depresses both LDL receptor activity and LDLr mRNA abundance in HepG2 cells
    • Lindsey S, Pronczuk A & Hayes KC (1992) Low density lipoprotein from humans supplemented with n-3 fatty acids depresses both LDL receptor activity and LDLr mRNA abundance in HepG2 cells. J Lipid Res 33, 647-658.
    • (1992) J Lipid Res , vol.33 , pp. 647-658
    • Lindsey, S.1    Pronczuk, A.2    Hayes, K.C.3
  • 29
    • 0033035417 scopus 로고    scopus 로고
    • Omega-3 fatty acids alter lipoprotein subfraction distributions and the in vitro conversion of very low density lipoproteins to low density lipoproteins
    • Lu G, Windsor SL & Harris WS (1999) Omega-3 fatty acids alter lipoprotein subfraction distributions and the in vitro conversion of very low density lipoproteins to low density lipoproteins. J Nutr Biochem 10, 151-158.
    • (1999) J Nutr Biochem , vol.10 , pp. 151-158
    • Lu, G.1    Windsor, S.L.2    Harris, W.S.3
  • 30
    • 84950170831 scopus 로고
    • Reduction of blood pressure and plasma triglycerides by omega-3 3 fatty acids in treated hypertensives
    • Lungershausen YK, Abbey M, Nestel PJ & Howe PRC (1994) Reduction of blood pressure and plasma triglycerides by omega-3 3 fatty acids in treated hypertensives. J Hypertens 12, 1041-1045.
    • (1994) J Hypertens , vol.12 , pp. 1041-1045
    • Lungershausen, Y.K.1    Abbey, M.2    Nestel, P.J.3    Howe, P.R.C.4
  • 31
    • 0032858328 scopus 로고    scopus 로고
    • Docosahexaenoic acid but not eicosapentaenoic acid lowers ambulatory blood pressure and heart rate in humans
    • Mori TA, Bao DQ, Burke V, Puddey IB & Beilin LJ (1999) Docosahexaenoic acid but not eicosapentaenoic acid lowers ambulatory blood pressure and heart rate in humans. Hypertension 34, 253-260.
    • (1999) Hypertension , vol.34 , pp. 253-260
    • Mori, T.A.1    Bao, D.Q.2    Burke, V.3    Puddey, I.B.4    Beilin, L.J.5
  • 32
    • 0034016538 scopus 로고    scopus 로고
    • Purified eicosapentaenoic and docosahexaenoic acids have differential effects on serum lipids and lipoproteins, LDL particle size, glucose, and insulin in mildly hyperlipidemic men
    • Mori TA, Burke V, Puddey IB, Watts GF, O'Neal DN, Best JD & Beilin LJ (2000) Purified eicosapentaenoic and docosahexaenoic acids have differential effects on serum lipids and lipoproteins, LDL particle size, glucose, and insulin in mildly hyperlipidemic men. Am J Clin Nutr 71, 1085-1094.
    • (2000) Am J Clin Nutr , vol.71 , pp. 1085-1094
    • Mori, T.A.1    Burke, V.2    Puddey, I.B.3    Watts, G.F.4    O'Neal, D.N.5    Best, J.D.6    Beilin, L.J.7
  • 33
    • 0030723366 scopus 로고    scopus 로고
    • The effect of dietary docosahexaenoic acid on plasma lipoproteins and tissue fatty acid composition in humans
    • Nelson GJ, Schmidt PC, Bartolini GL, Kelley DS & Kyle D (1997) The effect of dietary docosahexaenoic acid on plasma lipoproteins and tissue fatty acid composition in humans. Lipids 32, 1137-1146.
    • (1997) Lipids , vol.32 , pp. 1137-1146
    • Nelson, G.J.1    Schmidt, P.C.2    Bartolini, G.L.3    Kelley, D.S.4    Kyle, D.5
  • 34
    • 0033958138 scopus 로고    scopus 로고
    • Fish oil and cardiovascular disease: Lipids and arterial function
    • Nestel PJ (2000) Fish oil and cardiovascular disease: lipids and arterial function. Am J Clin Nutr 71, 228-231.
    • (2000) Am J Clin Nutr , vol.71 , pp. 228-231
    • Nestel, P.J.1
  • 35
    • 0036075998 scopus 로고    scopus 로고
    • The n-3 fatty acids eicosapentaenoic acid and docosahexaenoic acid increase systemic arterial compliance in humans
    • Nestel P, Shige H, Pomeroy M, Cehun M, Abbey M & Raederstorff D (2002) The n-3 fatty acids eicosapentaenoic acid and docosahexaenoic acid increase systemic arterial compliance in humans. Am J Clin Nutr 76, 326-330.
    • (2002) Am J Clin Nutr , vol.76 , pp. 326-330
    • Nestel, P.1    Shige, H.2    Pomeroy, M.3    Cehun, M.4    Abbey, M.5    Raederstorff, D.6
  • 36
    • 0029939180 scopus 로고    scopus 로고
    • Eicosapentaenoic acid is primarily responsible for hypotriglyceridemic effect of fish oil in humans
    • Rambjor GS, Walen AI, Windsor SL & Harris WS (1996) Eicosapentaenoic acid is primarily responsible for hypotriglyceridemic effect of fish oil in humans. Lipids 31, S45-S49.
    • (1996) Lipids , vol.31
    • Rambjor, G.S.1    Walen, A.I.2    Windsor, S.L.3    Harris, W.S.4
  • 37
    • 0026686919 scopus 로고
    • The influence of a fish oil high in docosahexaenoic acid on plasma lipoprotein and vitamin E concentrations and haemostatic function in healthy male volunteers
    • Sanders TAB & Hinds A (1992) The influence of a fish oil high in docosahexaenoic acid on plasma lipoprotein and vitamin E concentrations and haemostatic function in healthy male volunteers. Br J Nutr 68, 163-173.
    • (1992) Br J Nutr , vol.68 , pp. 163-173
    • Sanders, T.A.B.1    Hinds, A.2
  • 39
    • 2442445051 scopus 로고    scopus 로고
    • Differential eicosapentaenoic acid elevations and altered cardiovascular disease risk factor responses after supplementation with docosahexaenoic acid in postmenopausal women receiving and not receiving hormone replacement therapy
    • Stark KD & Holub BJ (2004) Differential eicosapentaenoic acid elevations and altered cardiovascular disease risk factor responses after supplementation with docosahexaenoic acid in postmenopausal women receiving and not receiving hormone replacement therapy. Am J Clin Nutr 79, 765-773.
    • (2004) Am J Clin Nutr , vol.79 , pp. 765-773
    • Stark, K.D.1    Holub, B.J.2
  • 40
    • 0026510624 scopus 로고
    • Dependence on dietary cholesterol for n-3 polyunsaturated fatty acid-induced changes in plasma cholesterol in the Syrian hamster
    • Surette ME, Whelan J, Lu GP, Broughton KS & Kinsella JE (1992) Dependence on dietary cholesterol for n-3 polyunsaturated fatty acid-induced changes in plasma cholesterol in the Syrian hamster. J Lipid Res 33, 263-271.
    • (1992) J Lipid Res , vol.33 , pp. 263-271
    • Surette, M.E.1    Whelan, J.2    Lu, G.P.3    Broughton, K.S.4    Kinsella, J.E.5
  • 42
    • 0028788418 scopus 로고
    • Effects of n-3 polyunsaturated fatty acids on glucose homeostasis and blood pressure in essential hypertension: A randomized, controlled trial
    • Toft I, Bonaa KH, Ingebretsen OC, Nordoy A & Jenssen T (1995) Effects of n-3 polyunsaturated fatty acids on glucose homeostasis and blood pressure in essential hypertension: a randomized, controlled trial. Ann Intern Med 123, 911-918.
    • (1995) Ann Intern Med , vol.123 , pp. 911-918
    • Toft, I.1    Bonaa, K.H.2    Ingebretsen, O.C.3    Nordoy, A.4    Jenssen, T.5


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