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Volumn 59, Issue 12, 2011, Pages 6790-6797

Microalga decreases plasma cholesterol by down-regulation of intestinal NPC1L1, hepatic LDL receptor, and HMG-CoA reductase

Author keywords

HMG CoA reductase; LDL receptor; microalga; NPC1L1; total cholesterol

Indexed keywords

HMG-COA REDUCTASE; LDL RECEPTOR; MICROALGA; NPC1L1; TOTAL CHOLESTEROL;

EID: 79959245466     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf200757h     Document Type: Article
Times cited : (29)

References (27)
  • 1
    • 70349418026 scopus 로고    scopus 로고
    • Innovative natural functional ingredients from microalgae
    • Plaza, M.; Herrero, M.; Cifuentes, A.; Ibanez, E. Innovative natural functional ingredients from microalgae J. Agric. Food Chem. 2009, 57, 7159-7170
    • (2009) J. Agric. Food Chem. , vol.57 , pp. 7159-7170
    • Plaza, M.1    Herrero, M.2    Cifuentes, A.3    Ibanez, E.4
  • 2
    • 32244444564 scopus 로고    scopus 로고
    • Chlorella vulgaris and Haematococcus pluvialis biomass as colouring and antioxidant in food emulsions
    • DOI 10.1007/s00217-005-0105-z
    • Gouveia, L.; Raymundo, A.; Batista, A. P.; Sousa, I.; Empis, J. Chlorella vulgaris and Haematococcus pluvialis biomass as colouring and antioxidant in food emulsions Eur. Food Res. Technol. 2006, 222, 362-367 (Pubitemid 43214128)
    • (2006) European Food Research and Technology , vol.222 , Issue.3-4 , pp. 362-367
    • Gouveia, L.1    Raymundo, A.2    Batista, A.P.3    Sousa, I.4    Empis, J.5
  • 3
    • 77955095940 scopus 로고    scopus 로고
    • Optimization of nitrogen source for enhanced production of squalene from thraustochytrid Aurantiochytrium sp
    • Chen, G. Q.; Fan, K. W.; Lu, F. P.; Li, Q.; Aki, T.; Chen, F.; Jiang, Y. Optimization of nitrogen source for enhanced production of squalene from thraustochytrid Aurantiochytrium sp New Biotechnol. 2010, 27, 382-389
    • (2010) New Biotechnol. , vol.27 , pp. 382-389
    • Chen, G.Q.1    Fan, K.W.2    Lu, F.P.3    Li, Q.4    Aki, T.5    Chen, F.6    Jiang, Y.7
  • 4
    • 79952279383 scopus 로고    scopus 로고
    • Present and potential industrial applications of macro- and microalgae
    • Sanghvi, A. M.; Lo, Y. M. Present and potential industrial applications of macro- and microalgae Recent Pat. Food Nutr. Agric. 2010, 2, 187-194
    • (2010) Recent Pat. Food Nutr. Agric. , vol.2 , pp. 187-194
    • Sanghvi, A.M.1    Lo, Y.M.2
  • 6
    • 54349087138 scopus 로고    scopus 로고
    • Cholesterol-lowering nutraceuticals and functional foods
    • Chen, Z. Y.; Jiao, R.; Ma, K. Y. Cholesterol-lowering nutraceuticals and functional foods J. Agric. Food Chem. 2008, 56, 8761-8773
    • (2008) J. Agric. Food Chem. , vol.56 , pp. 8761-8773
    • Chen, Z.Y.1    Jiao, R.2    Ma, K.Y.3
  • 7
    • 67649287981 scopus 로고    scopus 로고
    • Niemann-Pick C1 Like 1 (NPC1L1) an intestinal sterol transporter
    • Davis, H. R., Jr.; Altmann, S. W. Niemann-Pick C1 Like 1 (NPC1L1) an intestinal sterol transporter Biochim. Biophys. Acta 2009, 1791, 679-683
    • (2009) Biochim. Biophys. Acta , vol.1791 , pp. 679-683
    • Davis, Jr.H.R.1    Altmann, S.W.2
  • 8
    • 0346850861 scopus 로고    scopus 로고
    • Compared with Acyl-CoA:Cholesterol O-Acyltransferase (ACAT) 1 and Lecithin:Cholesterol Acyltransferase, ACAT2 Displays the Greatest Capacity to Differentiate Cholesterol from Sitosterol
    • DOI 10.1074/jbc.M308235200
    • Temel, R. E.; Gebre, A. K.; Parks, J. S.; Rudel, L. L. Compared with Acyl-CoA:cholesterol O -acyltransferase (ACAT) 1 and lecithin:cholesterol acyltransferase, ACAT2 displays the greatest capacity to differentiate cholesterol from sitosterol J. Biol. Chem. 2003, 278, 47594-47601 (Pubitemid 37523203)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.48 , pp. 47594-47601
    • Temel, R.E.1    Gebre, A.K.2    Parks, J.S.3    Rudel, L.L.4
  • 9
    • 68149162716 scopus 로고    scopus 로고
    • Choosing hamsters but not rats as a model for studying plasma cholesterol-lowering activity of functional foods
    • Zhang, Z. S.; Wang, H.; Jiao, R.; Peng, C.; Wong, Y. M.; Yeung, V. S. Y.; Huang, Y.; Chen, Z. Y. Choosing hamsters but not rats as a model for studying plasma cholesterol-lowering activity of functional foods Mol. Nutr. Food Res. 2009, 53, 921-930
    • (2009) Mol. Nutr. Food Res. , vol.53 , pp. 921-930
    • Zhang, Z.S.1    Wang, H.2    Jiao, R.3    Peng, C.4    Wong, Y.M.5    Yeung, V.S.Y.6    Huang, Y.7    Chen, Z.Y.8
  • 11
    • 17844398484 scopus 로고    scopus 로고
    • Preventing dyslipidemia by Chlorella pyrenoidosa in rats and hamsters after chronic high fat diet treatment
    • Cherng, J. Y.; Shih, M. F. Preventing dyslipidemia by Chlorella pyrenoidosa in rats and hamsters after chronic high fat diet treatment Life Sci. 2005, 76, 3001-3013
    • (2005) Life Sci. , vol.76 , pp. 3001-3013
    • Cherng, J.Y.1    Shih, M.F.2
  • 12
    • 34247552654 scopus 로고    scopus 로고
    • Lipid characterization of mangrove thraustochytrid - Schizochytrium mangrovei
    • DOI 10.1021/jf070058y
    • Fan, K. W.; Jiang, Y.; Fann, Y. W.; Chen, F. Lipid characterization of mangrove thraustochytrid- Schizochytrium mangrovei J. Agric. Food Chem. 2007, 55, 2906-2910 (Pubitemid 46668297)
    • (2007) Journal of Agricultural and Food Chemistry , vol.55 , Issue.8 , pp. 2906-2910
    • Fan, K.-W.1    Jiang, Y.2    Faan, Y.-W.3    Chen, F.4
  • 13
    • 1542317132 scopus 로고    scopus 로고
    • Fatty acid composition and squalene content of the marine microalga Schizochytrium mangrovei
    • Jiang, Y.; Fan, K. W.; Wong, R. T. Y.; Chen, F. Fatty acid composition and squalene content of the marine microalga Schizochytrium mangrovei J. Agric. Food Chem. 2004, 52, 1196-1200
    • (2004) J. Agric. Food Chem. , vol.52 , pp. 1196-1200
    • Jiang, Y.1    Fan, K.W.2    Wong, R.T.Y.3    Chen, F.4
  • 15
    • 79551541589 scopus 로고    scopus 로고
    • Dietary calcium decreases plasma cholesterol by down-regulation of intestinal NPC1L1 and MTP and up-regulation of CYP7A1 and ABCG 5/8 in hamsters
    • Ma, K. Y.; Yang, N.; Jiao, R.; Peng, C.; Guan, L.; Huang, Y.; Chen, Z. Y. Dietary calcium decreases plasma cholesterol by down-regulation of intestinal NPC1L1 and MTP and up-regulation of CYP7A1 and ABCG 5/8 in hamsters Mol. Nutr. Food Res. 2011, 55, 247-258
    • (2011) Mol. Nutr. Food Res. , vol.55 , pp. 247-258
    • Ma, K.Y.1    Yang, N.2    Jiao, R.3    Peng, C.4    Guan, L.5    Huang, Y.6    Chen, Z.Y.7
  • 16
    • 54349089072 scopus 로고    scopus 로고
    • Apple polyphenols inhibit plasma CETP activity and reduce the ratio of non-HDL to HDL
    • Lam, C. K.; Zhang, Z. S.; Yu, H. J.; Tsang, S. Y.; Huang, Y.; Chen, Z. Y. Apple polyphenols inhibit plasma CETP activity and reduce the ratio of non-HDL to HDL Mol. Nutr. Food Res. 2008, 52, 950-958
    • (2008) Mol. Nutr. Food Res. , vol.52 , pp. 950-958
    • Lam, C.K.1    Zhang, Z.S.2    Yu, H.J.3    Tsang, S.Y.4    Huang, Y.5    Chen, Z.Y.6
  • 17
    • 40949136584 scopus 로고    scopus 로고
    • Conjugated and non-conjugated octadecaenoic acids affect differently intestinal acyl coenzyme A:cholesterol acyltransferase activity
    • Lam, C. K.; Chen, J. N.; Cao, Y.; Yang, L.; Wong, Y. M.; Yeung, S. Y. V.; Yao, X. Q.; Huang, Y.; Chen, Z. Y. Conjugated and non-conjugated octadecaenoic acids affect differently intestinal acyl coenzyme A:cholesterol acyltransferase activity Atherosclerosis 2008, 198, 85-93
    • (2008) Atherosclerosis , vol.198 , pp. 85-93
    • Lam, C.K.1    Chen, J.N.2    Cao, Y.3    Yang, L.4    Wong, Y.M.5    Yeung, S.Y.V.6    Yao, X.Q.7    Huang, Y.8    Chen, Z.Y.9
  • 18
    • 0345620779 scopus 로고    scopus 로고
    • Jasmine green tea epicatechins are hypolipidemic in hamsters (Mesocricetus auratus) fed a high fat diet
    • Chan, P. T.; Fong, W. P.; Cheung, Y. L.; Huang, Y.; Ho, W. K. K.; Chen, Z. Y. Jasmine green tea epicatechins are hypolipidemic in hamsters fed a high fat diet J. Nutr. 1999, 129, 1094-1101 (Pubitemid 29250155)
    • (1999) Journal of Nutrition , vol.129 , Issue.6 , pp. 1094-1101
    • Chan, P.T.1    Fong, W.P.2    Cheung, Y.L.3    Huang, Y.4    Ho, W.K.K.5    Chen, Z.-Y.6
  • 19
    • 0029785877 scopus 로고    scopus 로고
    • Down-regulation of hepatic LDL receptor expression in experimental nephrosis
    • Vaziri, N. D.; Liang, K. H. Down-regulation of hepatic LDL receptor expression in experimental nephrosis Kidney Int. 1996, 50, 887-893 (Pubitemid 26302677)
    • (1996) Kidney International , vol.50 , Issue.3 , pp. 887-893
    • Vaziri, N.D.1    Liang, K.H.2
  • 20
    • 57349162139 scopus 로고    scopus 로고
    • Inhibiting intestinal NPC1L1 activity prevents diet-induced increase in biliary cholesterol in Golden Syrian hamsters
    • Valasek, M. A.; Repa, J. J.; Quan, G.; Dietschy, J. M.; Turley, S. D. Inhibiting intestinal NPC1L1 activity prevents diet-induced increase in biliary cholesterol in Golden Syrian hamsters Am. J. Physiol. Gastrointest. Liver Physiol. 2008, 295, 813-822
    • (2008) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.295 , pp. 813-822
    • Valasek, M.A.1    Repa, J.J.2    Quan, G.3    Dietschy, J.M.4    Turley, S.D.5
  • 21
    • 10044226295 scopus 로고    scopus 로고
    • Stanol esters decrease plasma cholesterol independently of intestinal ABC sterol transporters and Niemann-Pick C1-like 1 protein gene expression
    • DOI 10.1194/jlr.M400208-JLR200
    • Field, F. J.; Born, E.; Mathur, S. N. Stanol esters decrease plasma cholesterol independently of intestinal ABC sterol transporters and Niemann-Pick C1-like 1 protein gene expression J. Lipid Res. 2004, 45, 2252-2259 (Pubitemid 39602972)
    • (2004) Journal of Lipid Research , vol.45 , Issue.12 , pp. 2252-2259
    • Field, F.J.1    Born, E.2    Mathur, S.N.3
  • 22
    • 33847012545 scopus 로고    scopus 로고
    • Tumor necrosis factor-α induces intestinal insulin resistance and stimulates the overproduction of intestinal apolipoprotein B48-containing lipoproteins
    • Qin, B.; Qiu, W.; Avramoglu, R. K.; Adeli, K. Tumor necrosis factor-α induces intestinal insulin resistance and stimulates the overproduction of intestinal apolipoprotein B48-containing lipoproteins Diabetes 2007, 56, 450-461
    • (2007) Diabetes , vol.56 , pp. 450-461
    • Qin, B.1    Qiu, W.2    Avramoglu, R.K.3    Adeli, K.4
  • 23
    • 0026654796 scopus 로고
    • Regulatory effects of the saturated fatty acids 6:0 through 18:0 on hepatic low density lipoprotein receptor activity in the hamster
    • Woollett, L. A.; Spady, D. K.; Dietschy, J. M. Regulatory effects of the saturated fatty acids 6:0 through 18:0 on hepatic low density lipoprotein receptor activity in the hamster J. Clin. Invest. 1992, 89, 1133-1141
    • (1992) J. Clin. Invest. , vol.89 , pp. 1133-1141
    • Woollett, L.A.1    Spady, D.K.2    Dietschy, J.M.3
  • 24
    • 0030044691 scopus 로고    scopus 로고
    • Chronic administration of eicosapentaenoic acid and docosahexaenoic acid as ethyl esters reduced plasma cholesterol and changed the fatty acid composition in rat blood and organs
    • Frøyland, L.; Vaagenes, H.; Asiedu, D. K.; Garras, A.; Lie, O.; Berge, R. K. Chronic administration of eicosapentaenoic acid and docosahexaenoic acid as ethyl esters reduced plasma cholesterol and changed the fatty acid composition in rat blood and organs Lipids 1996, 31, 169-178 (Pubitemid 26066086)
    • (1996) Lipids , vol.31 , Issue.2 , pp. 169-178
    • Froyland, L.1    Vaagenes, H.2    Asiedu, D.K.3    Garras, A.4    Lie, O.5    Berge, R.K.6
  • 25
    • 44349126634 scopus 로고    scopus 로고
    • The cholesterol absorption inhibitor ezetimibe acts by blocking the sterol-induced internalization of NPC1L1
    • Ge, L.; Wang, J.; Qi, W.; Miao, H. H.; Cao, J.; Qu, Y. X.; Li, B. L.; Song, B. L. The cholesterol absorption inhibitor ezetimibe acts by blocking the sterol-induced internalization of NPC1L1 Cell Metab. 2008, 7, 469-471
    • (2008) Cell Metab. , vol.7 , pp. 469-471
    • Ge, L.1    Wang, J.2    Qi, W.3    Miao, H.H.4    Cao, J.5    Qu, Y.X.6    Li, B.L.7    Song, B.L.8
  • 26
    • 33846860854 scopus 로고    scopus 로고
    • Regulation of intestinal NPC1L1 expression by dietary fish oil and docosahexaenoic acid
    • DOI 10.1194/jlr.M600325-JLR200
    • Mathur, S. N.; Watt, K. R.; Field, F. J. Regulation of intestinal NPC1L1 expression by dietary fish oil and docosahexaenoic acid J. Lipid Res. 2007, 48, 395-404 (Pubitemid 46220606)
    • (2007) Journal of Lipid Research , vol.48 , Issue.2 , pp. 395-404
    • Mathur, S.N.1    Watt, K.R.2    Field, F.J.3
  • 27
    • 0033596281 scopus 로고    scopus 로고
    • Effect of statins on risk of coronary disease. A meta-analysis of randomized controlled trials
    • LaRosa, J. C.; He, J.; Vupputuri, S. Effect of stains on risk of coronary disease: a meta-analysis of randomized controlled trials JAMA, J. Am. Med. Assoc. 1999, 282, 2340-2346 (Pubitemid 30013066)
    • (1999) Journal of the American Medical Association , vol.282 , Issue.24 , pp. 2340-2346
    • LaRosa, J.C.1    He, J.2    Vupputuri, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.