Modification of phospholipids fatty acid composition in Reuber H35 hepatoma cells: Effect on HMG-CoA reductase activity

Journal of Cellular Biochemistry

Volumn 90, Issue 3, 2003, Pages 586-591

  García Pelayo, M Carmen ^a   García Peregrín, Eduardo ^a   Martínez Cayuela, Marina ^a  

^a UNIVERSITY OF GRANADA   (Spain)

Author keywords

HMG CoA reductase; N 3 polyunsaturated fatty acids; Phospholipids; Reuber H35 hepatoma cells; Saturated fatty acids

Indexed keywords

BOVINE SERUM ALBUMIN; CELL ENZYME; DOCOSAHEXAENOIC ACID; FATTY ACID; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; ICOSAPENTAENOIC ACID; LAURIC ACID; MYRISTIC ACID; OMEGA 3 FATTY ACID; POLYUNSATURATED FATTY ACID; SATURATED FATTY ACID;

ANIMAL CELL; ARTICLE; CELL ACTIVITY; CELL CULTURE; CHOLESTEROL SYNTHESIS; CONTROLLED STUDY; CULTURE MEDIUM; DIETARY INTAKE; ENZYME ACTIVITY; LIPID COMPOSITION; LIPOPROTEIN BLOOD LEVEL; LIVER CELL CARCINOMA; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; DOCOSAHEXAENOIC ACIDS; EICOSAPENTAENOIC ACID; ENZYME ACTIVATION; FATTY ACIDS; FATTY ACIDS, UNSATURATED; HYDROXYMETHYLGLUTARYL COA REDUCTASES; LIVER NEOPLASMS, EXPERIMENTAL; MEVALONIC ACID; PHOSPHOLIPIDS; TUMOR CELLS, CULTURED;

BOVINAE;

EID: 17344386987     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcb.10650     Document Type: Article

References (33)

1. Bailey PJ, Howard BV, Dunbar L, Tillman S. 1972. Control of lipid metabolism in cultured cells. Lipids 7:125-134.
2. Barnard GF, Erickson SK, Cooper AD. 1984. Lipoprotein metabolism by rat hepatomas. J Clin Invest 74:173-184.
3. Beirne OR, Watson JA. 1976. Comparison of regulation of 3-hydroxy-3-methylgluteryl coenzyme A reductase in hepatoma cells grown in vivo and in vitro. Proc Natl Acad Sci 73:2735-2739.
4. Bennis F, Favre G, Le Gaillard F, Soula FG. 1993. Importance of mevalonate-derived products in the control of HMG-CoA reductase activity and growth of human lung adenocarcinoma cell line. Int J Cancer 55:640-645.
5. Castillo M, Amalik F, Linares A, García-Peregrín E. 1999. Dietary fish oil reduces cholesterol and arachidonic acid levels in chick plasma and very low density lipoprotein. Mol Cell Biochem 200:59-67.
6. Castillo M, Hortal JH, Gil-Villarino A, Luque P, Iglesias J, García-Peregrín E. 1999a. Differential effects of dietary fat on chick plasma and liver composition and HMG-CoA reductase activity. J Nutr Biochem 10:198-204.
7. Castillo M, Amalik F, Linares A, García-Peregrín E. 2000. Fish oil reduces cholesterol and arachidonic acid levels in plasma and lipoproteins from hypercholesterolemic chicks. Mol Cell Biochem 210:121-130.
8. Choi YS, Goto S, Ikeda I, Sugano M. 1989. Effects of dietary n-3 polyunsaturated fatty acids on cholesterol synthesis and degradation in rats of different ages. Lipids 24:45-50.
9. Daumerie C, Woollett L, Dietschy JM. 1992. Fatty acids regulate hepatic low density receptor activity through redistribution of intracellular cholesterol pools. Proc Natl Acad Sci 89:10797-10801.
10. Donato MT, Bassi AM, Gómez-Lechón MJ, Penco S, Herrero E, Adamo D, Castell JV, Ferro M. 1994. Evaluation of the xenobiotic biotransformation capability of six rodent hepatoma cell lines in comparison with rat hepatocytes. In Vitro Cell Dev Biol Anim 30:574-580.
11. Eisenberg DA. 1998. Cholesterol lowering in the management of coronary artery disease: The clinical implications of recent trials. Am J Med 104:2S-5S.
12. Folch J, Lees M, Stanley GSH. 1957. A simple method for isolation and purification of total lipids from animal tissue. J Biol Chem 226:497-509.
13. García-Pelayo MC, García-Peregrín E, Martínez-Cayuela M. 2000. An improved assay of 3-hydroxy-3-methylglutaryl-CoA reductase activity in Reuber H35 hepatoma cells without microsomes isolation. Analyst 125:1583-1585.
14. Gil-Villarino A. 1998. Doctoral Thesis. University of Granada. Spain.
15. Gil-Villarino A, García-Fuentes E, Zafra MF, Garcí a-Peregrín E. 1998. Production of a rapid hypercholesterolemia in young chick by feeding coconut oil from two different sources and fatty acid composition. Nutr Res 18:1273-1285.
16. Grundy SM, Denke MA. 1990. Dietary influences on serum lipids and lipoproteins. J Lipid Res 31:1149-1172.
17. Hayes KC, Khosla P. 1992. Dietary fatty acid thresholds and cholesterolemia. FASEB J 6:2600-2607.
18. Hayes KC, Pronczuk A, Lindsey D, Diersen-Schade D. 1991. Dietary saturated fatty acids (12:0, 14:0, 16:0) differ in their impact on plasma cholesterol and lipoproteins in non-human primates. Am J Clin Nutr 53:491-498.
19. Khosla P, Hayes KC. 1991. Dietary fat saturation in rhesus monkeys affects LDL concentration by modulating the independent production of LDL apolipoprotein B. Biochim Biophys Acta 1083:46-56.
20. Lepage G, Roy CC. 1986. Direct transesterification of all classes of lipids in one-step reaction. J Lipid Res 27:114-120.
21. Lindsey S, Pronczuk A, Hayes KC. 1992. Low density lipoprotein from human supplemented with n-3 fatty acids depresses both LDL receptor activity and LDLr mRNA abundance in HepG2 cells. J Lipid Res 33:647-658.
22. Martínez-Cayuela M, García-Pelayo MC, Linares A, García-Peregrín E. 2000. Metabolism of palmitic and docosahexaenoic acid in Reuber H35 hepatoma cells. J Biochem 128:545-551.
23. Mizuguchi K, Yano T, Tanaka Y, Ishibashi M, Masada A, Mizota M, Fukutake K, Saito Y. 1993. Mechanism of the lipid-lowering effect of ethyl all-cis-5,8,11,14,17 eicosapentaenoate. Eur J Pharmacol 231:121-127.
24. Murthy S, Albright E, Mathur SN, Field FJ. 1988. Modification of CaCo-2 cell membrane fatty acid composition by eicosapentaenoic acid and palmitic acid: Effect on cholesterol metabolism. J Lipid Res 29:773-780.
25. Poumay Y, Ronveaux-Dupol MF. 1985. Rapid preparative isolation of concentrated low density lipoproteins and of lipoprotein deficient serum using vertical rotor gradient ultracentrifugation. J Lipid Res 26:1476-1480.
26. Rumsey S, Galeano NF, Lipschitz B, Deckelbaum RJ. 1995. Oleate and other long chain fatty acids stimulate low density lipoprotein receptor activity by enhancing acyl coenzyme A: Cholesterol acyltransferase activity and altering intracellular regulatory cholesterol pools in cultured cells. J Biol Chem 270:10008-10016.
27. Sato R, Takano T. 1995. Regulation of intracellular cholesterol metabolism. Cell Struct Func 20:421-427.
28. Shapiro DJ, Nordstrom JL, Mitschelen JJ, Rodwell VW, Schimke RT. 1974. Micro assay for 3-hydroxy-3-methylglutaryl-CoA reductase in rat liver and in L-cell fibroblasts. Biochim Biophys Acta 370:369-377.
29. Skipsky VP, Barclay M. 1969. Thin layer chromatography of lipids. Meth Enzymol 16:548-550.
30. Spector AA, Yorek MA. 1985. Membrane lipid composition and cellular function. J Lipid Res 26:1015-1035.
31. van Amerongen A, Teerlink T, van Heusden GPH, Wirtz KWA. 1985. The non-specific lipid transfer protein (sterol carrier protein 2) from rat and bovine liver. Chem Phys Lipids 38:195-204.
32. van Heusden GPH, Souren J, Geelen MJH, Wirtz KWA. 1985. The synthesis and esterification of cholesterol by hepatocytes and H35 hepatoma cells are independent of the level of nonspecific lipid transfer protein. Biochim Biophys Acta 846:21-25.
33. Wiegant FAC, van Rijn J, van Wijk R. 1997. Enhancement of the stress response by minute amounts of cadmium in sensitized Reuber H35 hepatoma cells. Toxicology 116:27-37.