The use of 13C solid state NMR to elucidate physico-chemical association in Eudragit® RS100 microencapsulated acyl esters of salicylic acid

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 45, Issue 1, 1998, Pages 9-21

  Vachon, Michael G ^a   Graham Nairn, J ^b  

^a UNIVERSITY OF LIMOGES   (France)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

13C solid state nuclear magnetic resonance; Electrostatic association; Esterified drug; Eudragit RS100; Hydrolysis; Microsphere

Indexed keywords

ACETYLSALICYLIC ACID; CAPRYLSALICYCLIC ACID; EUDRAGIT RS; MICROSPHERE; SALICYLIC ACID; UNCLASSIFIED DRUG; VALERYLSALICYCLIC ACID; ACRYLIC ACID RESIN; CARBON; DRUG CARRIER; METHYLMETHACRYLATE METHACRYLIC ACID COPOLYMER; METHYLMETHACRYLATE-METHACRYLIC ACID COPOLYMER; POLYMETHACRYLIC ACID DERIVATIVE; SALICYLIC ACID DERIVATIVE;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; DRUG DELIVERY SYSTEM; ENCAPSULATION; ESTERIFICATION; HYDROLYSIS; MICROENCAPSULATION; CHEMISTRY; DRUG FORMULATION; ELECTRICITY; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

ACRYLIC RESINS; CARBON ISOTOPES; DRUG CARRIERS; DRUG COMPOUNDING; ELECTROSTATICS; HYDROLYSIS; MAGNETIC RESONANCE SPECTROSCOPY; MICROSPHERES; POLYMETHACRYLIC ACIDS; SALICYLIC ACID; SALICYLIC ACIDS;

EID: 0031595654     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0939-6411(97)00118-5     Document Type: Article

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