-
1
-
-
0037239541
-
Peptide-polymer bioconjugates: hybrid block copolymers generated via living radical polymerizations from resin-supported peptides
-
M.L. Becker, and K.L. Wooley Peptide-polymer bioconjugates: hybrid block copolymers generated via living radical polymerizations from resin-supported peptides Chem Commun (Camb) 2003 180 181
-
(2003)
Chem Commun (Camb)
, pp. 180-181
-
-
Becker, M.L.1
Wooley, K.L.2
-
2
-
-
0038387390
-
The dawning era of polymer therapeutics
-
R. Duncan The dawning era of polymer therapeutics Nat Rev Drug Discov 2 2003 347 360 A comprehensive review of polymer-based delivery system, with insights into future potential breakthrough approaches.
-
(2003)
Nat Rev Drug Discov
, vol.2
, pp. 347-360
-
-
Duncan, R.1
-
3
-
-
0141765877
-
Small-scale systems for in-vivo drug delivery
-
La Van DA, McGuire T, Langer R: Small-scale systems for in-vivo drug delivery. Nat Biotechnol 21, 10:184-1191, 2003.
-
(2003)
Nat Biotechnol
, vol.21
, Issue.10
, pp. 184-1191
-
-
La Van, D.A.1
McGuire, T.2
Langer, R.3
-
4
-
-
0035816145
-
Development of the polymer micelle carrier system for doxorubicin
-
T. Nakanishi, S. Fukushima, K. Okamoto, M. Suzuki, Y. Matsumura, M. Yokoyama, T. Okano, Y. Sakurai, and K. Kataoka Development of the polymer micelle carrier system for doxorubicin J Control Release 74 2001 295 302
-
(2001)
J Control Release
, vol.74
, pp. 295-302
-
-
Nakanishi, T.1
Fukushima, S.2
Okamoto, K.3
Suzuki, M.4
Matsumura, Y.5
Yokoyama, M.6
Okano, T.7
Sakurai, Y.8
Kataoka, K.9
-
5
-
-
0035966497
-
Biodegradable polymeric nanoparticles as drug delivery devices
-
K.S. Soppimath, and W.E. Rudzinski Biodegradable polymeric nanoparticles as drug delivery devices J Control Release 70 2001 1 20
-
(2001)
J Control Release
, vol.70
, pp. 1-20
-
-
Soppimath, K.S.1
Rudzinski, W.E.2
-
6
-
-
0036899037
-
Biological applications of dendrimers
-
M.J. Cloninger Biological applications of dendrimers Curr Opin Chem Biol 6 2002 742 748
-
(2002)
Curr Opin Chem Biol
, vol.6
, pp. 742-748
-
-
Cloninger, M.J.1
-
7
-
-
0037184446
-
Designing macromolecules for therapeutic applications: Polyester dendrimer-polyethylene oxide 'bow-tie' hybrids with tunable molecular weights and architecture
-
E.R. Gilles, and J.M.J. Frechet Designing macromolecules for therapeutic applications: Polyester dendrimer-polyethylene oxide 'bow-tie' hybrids with tunable molecular weights and architecture J Am Chem Soc 124 2002 14137 14146
-
(2002)
J Am Chem Soc
, vol.124
, pp. 14137-14146
-
-
Gilles, E.R.1
Frechet, J.M.J.2
-
8
-
-
0036744856
-
Design and function of a dendrimer-based therapeutic nanodevice targeted to tumor cells through the folate receptor
-
A. Quintana, and J.N. Baker Jr. Design and function of a dendrimer-based therapeutic nanodevice targeted to tumor cells through the folate receptor Pharm Res 19 2002 1310 1316
-
(2002)
Pharm Res
, vol.19
, pp. 1310-1316
-
-
Quintana, A.1
Baker Jr., J.N.2
-
9
-
-
0042698669
-
Reduced symmetry metallodielectric nanoparticles: chemical synthesis and plasmonic properties
-
C. Charnay, and N.J. Halas Reduced symmetry metallodielectric nanoparticles: chemical synthesis and plasmonic properties J Phys Chem B 107 2003 7327 7333 Insight into the fabrication of gold nanoshells may yield inspiration for the mathematical modeling of their plasmonic response, towards tunability of the system.
-
(2003)
J Phys Chem B
, vol.107
, pp. 7327-7333
-
-
Charnay, C.1
Halas, N.J.2
-
10
-
-
0345686712
-
Nanoshell-mediated near-infrared thermal therapy of tumors under magnetic resonance guidance
-
L.R. Hirsch, N.J. Halas, and J.L. West Nanoshell-mediated near-infrared thermal therapy of tumors under magnetic resonance guidance Proc Natl Acad Sci USA 100 2003 13549 13554
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 13549-13554
-
-
Hirsch, L.R.1
Halas, N.J.2
West, J.L.3
-
12
-
-
2442692534
-
Photo-thermal tumor ablation in mice using near infrared-absorbing nanoparticles
-
D.P. O'Neal, N.J. Halas, and J.L. West Photo-thermal tumor ablation in mice using near infrared-absorbing nanoparticles Cancer Lett 209 2004 171 176
-
(2004)
Cancer Lett
, vol.209
, pp. 171-176
-
-
O'Neal, D.P.1
Halas, N.J.2
West, J.L.3
-
13
-
-
0036792082
-
Nanocrystal targeting in vivo
-
M.E. Akerman, W.C.W. Chan, P. Laakkonen, S.N. Bhatia, and E. Ruoslahti Nanocrystal targeting in vivo Proc Natl Acad Sci USA 99 2002 12617 12621
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 12617-12621
-
-
Akerman, M.E.1
Chan, W.C.W.2
Laakkonen, P.3
Bhatia, S.N.4
Ruoslahti, E.5
-
14
-
-
0842287342
-
Probing the cytotoxicity of semiconductor quantum dots
-
A.M. Derfus, W.C.W. Chan, and S.N. Bhatia Probing the cytotoxicity of semiconductor quantum dots Nano Lett 4 2004 11 18 Nanoparticle biocompatibility is a fundamental concern. The methods displayed in this paper may guide researchers working with different nanoparticle formulations, as well.
-
(2004)
Nano Lett
, vol.4
, pp. 11-18
-
-
Derfus, A.M.1
Chan, W.C.W.2
Bhatia, S.N.3
-
15
-
-
0037497251
-
Chaperonin-mediated stabilization and ATP-triggered release of semiconductor nanoparticles
-
D. Ishii, and T. Aida Chaperonin-mediated stabilization and ATP-triggered release of semiconductor nanoparticles Nature 423 2003 628 632 Adapting nanovector design to attain preferential, locally triggered activation offers potential advantages in therapeutic index.
-
(2003)
Nature
, vol.423
, pp. 628-632
-
-
Ishii, D.1
Aida, T.2
-
16
-
-
0037503818
-
Hybrid virus-polymer materials. 1. Synthesis and properties of PEG-decorated cowpea mosaic virus
-
K.S. Raja, M. Manchester, and M.G. Finn Hybrid virus-polymer materials. 1. Synthesis and properties of PEG-decorated cowpea mosaic virus Biomacromolecules 4 2003 472 476
-
(2003)
Biomacromolecules
, vol.4
, pp. 472-476
-
-
Raja, K.S.1
Manchester, M.2
Finn, M.G.3
-
17
-
-
0038451393
-
Bioconjugated nanoparticles for DNA protection from cleavage
-
X.X. He, and J. Li Bioconjugated nanoparticles for DNA protection from cleavage J Am Chem Soc 125 2003 7168 7169
-
(2003)
J Am Chem Soc
, vol.125
, pp. 7168-7169
-
-
He, X.X.1
Li, J.2
-
18
-
-
0037015983
-
DNA nanoparticles and development of DNA delivery vehicles for gene therapy
-
V. Vijayanathan, and T.J. Thomas DNA nanoparticles and development of DNA delivery vehicles for gene therapy Biochemistry 41 2002 14085 14094
-
(2002)
Biochemistry
, vol.41
, pp. 14085-14094
-
-
Vijayanathan, V.1
Thomas, T.J.2
-
19
-
-
0142062528
-
Microfabrication of silicon-based nanoporous particulates for medical applications
-
M.H. Cohen, K. Melnik, A. Boiarski, M. Ferrari, and F.J. Martin Microfabrication of silicon-based nanoporous particulates for medical applications Biomedical Microdevices 5 2003 253 259
-
(2003)
Biomedical Microdevices
, vol.5
, pp. 253-259
-
-
Cohen, M.H.1
Melnik, K.2
Boiarski, A.3
Ferrari, M.4
Martin, F.J.5
-
20
-
-
33044501306
-
-
Therapeutic Microdevices and Methods of Making and Using Same. US Patent No. 6,107,102, August 22, 2000.
-
Ferrari M: Therapeutic Microdevices and Methods of Making and Using Same. US Patent No. 6,107,102, August 22, 2000. Multiple concepts and designs for injected delivery systems are presented.
-
-
-
Ferrari, M.1
-
21
-
-
0347761656
-
The embedding of meta-tetra(hydroxyphenyl)-chlorin into silica nanoparticle platforms for photodynamic therapy and their singlet oxygen production and pH-dependent optical properties
-
F. Yan, and R. Kopelman The embedding of meta-tetra(hydroxyphenyl)- chlorin into silica nanoparticle platforms for photodynamic therapy and their singlet oxygen production and pH-dependent optical properties Photoch Photobiol 78 2003 587 591
-
(2003)
Photoch Photobiol
, vol.78
, pp. 587-591
-
-
Yan, F.1
Kopelman, R.2
-
22
-
-
2342555661
-
Synthesis and characterization of silica-embedded iron oxide nanoparticles for magnetic resonance imaging
-
F. Yan, R. Kopelman, and R. Reddy Synthesis and characterization of silica-embedded iron oxide nanoparticles for magnetic resonance imaging J Nanosci Nanotechnol 4 2004 72 76
-
(2004)
J Nanosci Nanotechnol
, vol.4
, pp. 72-76
-
-
Yan, F.1
Kopelman, R.2
Reddy, R.3
-
23
-
-
0036861756
-
Engineering tumor-targeted gadolinium hexanedione nanoparticles for potential application in neutron capture therapy
-
M.O. Oyewumi, and R.J. Mumper Engineering tumor-targeted gadolinium hexanedione nanoparticles for potential application in neutron capture therapy Bioconjug Chem 13 2002 1328 1335
-
(2002)
Bioconjug Chem
, vol.13
, pp. 1328-1335
-
-
Oyewumi, M.O.1
Mumper, R.J.2
-
24
-
-
12144288759
-
A novel antiangiogenesis therapy using an integrin antagonist or anti-Flk-1 antibody coated 90Y-labeled nanoparticles
-
L. Li, C.A. Wartchow, S.N. Danthi, Z. Shen, N. Dechene, J. Pease, H.S. Choi, T. Doede, P. Chu, and S. Ning A novel antiangiogenesis therapy using an integrin antagonist or anti-Flk-1 antibody coated 90Y-labeled nanoparticles Int J Radiat Oncol Biol Phys 58 2004 1215 1227 Nanoparticles are generally excluded from extravasation through healthy vasculature, because of their 'large' size. This actually presents an opportunity: improved conditions for the localization on neoplastic endothelium, and the delivery of antiangiogenesis therapy thereon (see also [ 20,27 ]).
-
(2004)
Int J Radiat Oncol Biol Phys
, vol.58
, pp. 1215-1227
-
-
Li, L.1
Wartchow, C.A.2
Danthi, S.N.3
Shen, Z.4
Dechene, N.5
Pease, J.6
Choi, H.S.7
Doede, T.8
Chu, P.9
Ning, S.10
-
25
-
-
0142074730
-
Folic acid-conjugated nanostructured materials designed for cancer cell targeting
-
D. Pan, and K.L. Wooley Folic acid-conjugated nanostructured materials designed for cancer cell targeting Chem Commun (Camb) 2003 2400 2401
-
(2003)
Chem Commun (Camb)
, pp. 2400-2401
-
-
Pan, D.1
Wooley, K.L.2
-
27
-
-
0141731298
-
Molecular imaging of angiogenesis in nascent Vx-2 rabbit tumors using a novel alpha(nu)beta3-targeted nanoparticle and 1.5 Tesla magnetic resonance imaging
-
P.M. Winter, S.A. Wickline, and G.M. Lanza Molecular imaging of angiogenesis in nascent Vx-2 rabbit tumors using a novel alpha(nu)beta3-targeted nanoparticle and 1.5 Tesla magnetic resonance imaging Cancer Res 63 2003 5838 5843
-
(2003)
Cancer Res
, vol.63
, pp. 5838-5843
-
-
Winter, P.M.1
Wickline, S.A.2
Lanza, G.M.3
-
28
-
-
3242715145
-
Adhesion of micro-fabricated particles on vascular endothelium: a parametric analysis
-
P.S. Decuzzi, L.M. Decuzzi, and M. Ferrari Adhesion of micro-fabricated particles on vascular endothelium: a parametric analysis Annals Biomed Eng 32 2004 793 802
-
(2004)
Annals Biomed Eng
, vol.32
, pp. 793-802
-
-
Decuzzi, P.S.1
Decuzzi, L.M.2
Ferrari, M.3
-
29
-
-
33044494863
-
Non-specific interaction of nanoparticles as drug delivery and nanoharvesting agents within the vasculature
-
in press.
-
Decuzzi P, Lee S, Bhushan B, Ferrari M: Non-specific interaction of nanoparticles as drug delivery and nanoharvesting agents within the vasculature. Annals Biomed Eng 2005, in press. Mathematics will be increasingly important for bringing nanotechnology to full fruition in medicine.
-
(2005)
Annals Biomed Eng
-
-
Decuzzi, P.1
Lee, S.2
Bhushan, B.3
Ferrari, M.4
-
30
-
-
0016612425
-
Effect of particle size and charge on the clearance rates of liposomes and liposome-encapsulated drugs
-
R.L. Juliano, and D. Stamp Effect of particle size and charge on the clearance rates of liposomes and liposome-encapsulated drugs Biochem Biophys Res Commun 63 1975 651 658
-
(1975)
Biochem Biophys Res Commun
, vol.63
, pp. 651-658
-
-
Juliano, R.L.1
Stamp, D.2
-
31
-
-
0034114282
-
Vascular permeability in a human tumor xenograft: molecular charge dependence
-
M. Dellian, F. Yuan, V.S. Trubetskoy, V.P. Torchilin, and R.K. Jain Vascular permeability in a human tumor xenograft: molecular charge dependence Br J Cancer 82 2000 1513 1518
-
(2000)
Br J Cancer
, vol.82
, pp. 1513-1518
-
-
Dellian, M.1
Yuan, F.2
Trubetskoy, V.S.3
Torchilin, V.P.4
Jain, R.K.5
-
32
-
-
0038202316
-
Ceramic-based nanoparticles entrapping water-insoluble photosensitizing anticancer drugs: a novel drug-carrier system for photodynamic therapy
-
I. Roy, E.J. Bergey, and P.N. Prasad Ceramic-based nanoparticles entrapping water-insoluble photosensitizing anticancer drugs: a novel drug-carrier system for photodynamic therapy J Am Chem Soc 125 2003 7860 7865
-
(2003)
J Am Chem Soc
, vol.125
, pp. 7860-7865
-
-
Roy, I.1
Bergey, E.J.2
Prasad, P.N.3
-
34
-
-
0036917032
-
DC magnetic field induced magnetocytolysis of cancer cells targeted by LH-RH magnetic nanoparticles in vitro
-
E.J. Bergey, and P.N. Prasad DC magnetic field induced magnetocytolysis of cancer cells targeted by LH-RH magnetic nanoparticles in vitro Biomedical Microdevices 4 2002 293 299
-
(2002)
Biomedical Microdevices
, vol.4
, pp. 293-299
-
-
Bergey, E.J.1
Prasad, P.N.2
-
35
-
-
12244283699
-
Poly(ethylene oxide)-modified poly(beta-amino ester) nanoparticles as a pH-sensitive biodegradable system for paclitaxel delivery
-
A. Potineni, R. Langer, and M.M. Amiji Poly(ethylene oxide)-modified poly(beta-amino ester) nanoparticles as a pH-sensitive biodegradable system for paclitaxel delivery J Control Release 86 2003 223 234
-
(2003)
J Control Release
, vol.86
, pp. 223-234
-
-
Potineni, A.1
Langer, R.2
Amiji, M.M.3
-
36
-
-
0344185347
-
In situ blood-brain barrier transport of nanoparticles
-
J.M. Koziara, D.D. Allen, and R.J. Mumper In situ blood-brain barrier transport of nanoparticles Pharm Res 20 2003 1772 1778
-
(2003)
Pharm Res
, vol.20
, pp. 1772-1778
-
-
Koziara, J.M.1
Allen, D.D.2
Mumper, R.J.3
-
37
-
-
0036205158
-
Nanoparticle technology for drug deliver across the blood-brain barrier
-
P.R. Lockman, and D.D. Allen Nanoparticle technology for drug deliver across the blood-brain barrier Drug Dev Ind Pharm 28 2002 1 13
-
(2002)
Drug Dev Ind Pharm
, vol.28
, pp. 1-13
-
-
Lockman, P.R.1
Allen, D.D.2
-
38
-
-
0344009673
-
Brain uptake of thiamine-coated nanoparticles
-
P.R. Lockman, and D.D. Allen Brain uptake of thiamine-coated nanoparticles J Control Release 93 2003 271 282
-
(2003)
J Control Release
, vol.93
, pp. 271-282
-
-
Lockman, P.R.1
Allen, D.D.2
-
39
-
-
0347626110
-
A multimodal nanoparticle for preoperative magnetic resonance imaging and intraoperative optical brain tumor delineation
-
M.F. Kircher, U. Mahmood, R.S. King, R. Weissleder, and L. Josephson A multimodal nanoparticle for preoperative magnetic resonance imaging and intraoperative optical brain tumor delineation Cancer Res 63 2003 8122 8125
-
(2003)
Cancer Res
, vol.63
, pp. 8122-8125
-
-
Kircher, M.F.1
Mahmood, U.2
King, R.S.3
Weissleder, R.4
Josephson, L.5
-
40
-
-
7044253728
-
Imaging of iron oxide nanoparticles with MR and light microscopy in patients with malignant brain tumors
-
E.A. Neuwelt, P. Varallyay, A.G. Bago, L.L. Muldoon, G. Nesbit, and R. Nixon Imaging of iron oxide nanoparticles with MR and light microscopy in patients with malignant brain tumors Neuropathol Appl Neurobiol 30 2004 456 471
-
(2004)
Neuropathol Appl Neurobiol
, vol.30
, pp. 456-471
-
-
Neuwelt, E.A.1
Varallyay, P.2
Bago, A.G.3
Muldoon, L.L.4
Nesbit, G.5
Nixon, R.6
-
41
-
-
12144288634
-
Chemotherapy of glioblastoma in rats using doxorubicin-loaded nanoparticles
-
S.C. Steiniger, and S.E. Gelperina Chemotherapy of glioblastoma in rats using doxorubicin-loaded nanoparticles Int J Cancer 109 2004 759 767
-
(2004)
Int J Cancer
, vol.109
, pp. 759-767
-
-
Steiniger, S.C.1
Gelperina, S.E.2
-
42
-
-
33044500306
-
-
Particles for Oral Delivery of Peptides and Proteins. US Patent No. 6,355,270, March 12, 2002.
-
Ferrari M, Martin F, Grove C: Particles for Oral Delivery of Peptides and Proteins. US Patent No. 6,355,270, March 12, 2002.
-
-
-
Ferrari, M.1
Martin, F.2
Grove, C.3
-
43
-
-
0036096806
-
Liposome-based drug delivery in breast cancer treatment
-
J.W. Park Liposome-based drug delivery in breast cancer treatment Breast Cancer Res 4 2002 95 99
-
(2002)
Breast Cancer Res
, vol.4
, pp. 95-99
-
-
Park, J.W.1
-
44
-
-
14644439267
-
Cancer nanotechnology: opportunities and challenges
-
M. Ferrari Cancer nanotechnology: opportunities and challenges Nat Rev Cancer 5 2005 161 171
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 161-171
-
-
Ferrari, M.1
|