-
1
-
-
82855181165
-
Erythropoietin protects against doxorubicin-induced heart failure
-
Ammar H.I., Saba S., Ammar R.I., et al. Erythropoietin protects against doxorubicin-induced heart failure. Am J Physiol Heart Circ Physiol 2011, 301:H2413-H2421.
-
(2011)
Am J Physiol Heart Circ Physiol
, vol.301
-
-
Ammar, H.I.1
Saba, S.2
Ammar, R.I.3
-
2
-
-
75549090275
-
MTOR regulation and therapeutic rejuvenation of aging hematopoietic stem cells
-
Chen C., Liu Y., Zheng P. mTOR regulation and therapeutic rejuvenation of aging hematopoietic stem cells. Sci Signal 2009, 2:ra75.
-
(2009)
Sci Signal
, vol.2
-
-
Chen, C.1
Liu, Y.2
Zheng, P.3
-
3
-
-
79955731167
-
EPO relies upon novel signaling of Wnt1 that requires Akt1, FoxO3a, GSK-3β, and β-catenin to foster vascular integrity during experimental diabetes
-
Chong Z.Z., Hou J., Shang Y.C., et al. EPO relies upon novel signaling of Wnt1 that requires Akt1, FoxO3a, GSK-3β, and β-catenin to foster vascular integrity during experimental diabetes. Curr Neurovasc Res 2011, 8:103-120.
-
(2011)
Curr Neurovasc Res
, vol.8
, pp. 103-120
-
-
Chong, Z.Z.1
Hou, J.2
Shang, Y.C.3
-
4
-
-
18844434370
-
Oxidative stress in the brain: Novel cellular targets that govern survival during neurodegenerative disease
-
Chong Z.Z., Li F., Maiese K. Oxidative stress in the brain: Novel cellular targets that govern survival during neurodegenerative disease. Prog Neurobiol 2005, 75:207-246.
-
(2005)
Prog Neurobiol
, vol.75
, pp. 207-246
-
-
Chong, Z.Z.1
Li, F.2
Maiese, K.3
-
5
-
-
79951529849
-
Mammalian target of rapamycin: Hitting the bull's-eye for neurological disorders
-
Chong Z.Z., Shang Y.C., Zhang L., et al. Mammalian target of rapamycin: Hitting the bull's-eye for neurological disorders. Oxid Med Cell Longev 2010, 3:374-391.
-
(2010)
Oxid Med Cell Longev
, vol.3
, pp. 374-391
-
-
Chong, Z.Z.1
Shang, Y.C.2
Zhang, L.3
-
6
-
-
79952575620
-
Taurine suppresses doxorubicin-triggered oxidative stress and cardiac apoptosis in rat via up-regulation of PI3-K/Akt and inhibition of p53, p38-JNK
-
Das J., Ghosh J., Manna P., Sil P.C. Taurine suppresses doxorubicin-triggered oxidative stress and cardiac apoptosis in rat via up-regulation of PI3-K/Akt and inhibition of p53, p38-JNK. Biochem Pharmacol 2011, 81:891-909.
-
(2011)
Biochem Pharmacol
, vol.81
, pp. 891-909
-
-
Das, J.1
Ghosh, J.2
Manna, P.3
Sil, P.C.4
-
7
-
-
34548178582
-
The effects of mTOR-Akt interactions on anti-apoptotic signaling in vascular endothelial cells
-
Dormond O., Madsen J.C., Briscoe D.M. The effects of mTOR-Akt interactions on anti-apoptotic signaling in vascular endothelial cells. J Biol Chem 2007, 282:23679-23686.
-
(2007)
J Biol Chem
, vol.282
, pp. 23679-23686
-
-
Dormond, O.1
Madsen, J.C.2
Briscoe, D.M.3
-
8
-
-
77954945936
-
MTOR-mediated activation of p70 S6K induces differentiation of pluripotent human embryonic stem cells
-
Easley C.A., Ben-Yehudah A., Redinger C.J., et al. mTOR-mediated activation of p70 S6K induces differentiation of pluripotent human embryonic stem cells. Cell Reprogram 2010, 12:263-273.
-
(2010)
Cell Reprogram
, vol.12
, pp. 263-273
-
-
Easley, C.A.1
Ben-Yehudah, A.2
Redinger, C.J.3
-
9
-
-
79151484284
-
Modulation of human embryonic stem cell-derived cardiomyocyte growth: A testbed for studying human cardiac hypertrophy?
-
Földes G., Mioulane M., Wright J.S., et al. Modulation of human embryonic stem cell-derived cardiomyocyte growth: A testbed for studying human cardiac hypertrophy?. J Mol Cell Cardiol 2011, 50:367-376.
-
(2011)
J Mol Cell Cardiol
, vol.50
, pp. 367-376
-
-
Földes, G.1
Mioulane, M.2
Wright, J.S.3
-
10
-
-
6344245674
-
Disruption of the mouse mTOR gene leads to early postimplantation lethality and prohibits embryonic stem cell development
-
Gangloff Y.G., Mueller M., Dann S.G., et al. Disruption of the mouse mTOR gene leads to early postimplantation lethality and prohibits embryonic stem cell development. Mol Cell Biol 2004, 24:9508-9516.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 9508-9516
-
-
Gangloff, Y.G.1
Mueller, M.2
Dann, S.G.3
-
11
-
-
82555187786
-
A novel cardioprotective p38-MAPK/mTOR pathway
-
Hernández G., Lal H., Fidalgo M., et al. A novel cardioprotective p38-MAPK/mTOR pathway. Exp Cell Res 2011, 317:2938-2949.
-
(2011)
Exp Cell Res
, vol.317
, pp. 2938-2949
-
-
Hernández, G.1
Lal, H.2
Fidalgo, M.3
-
12
-
-
72849126360
-
Pivotal role for glycogen synthase kinase-3 in hematopoietic stem cell homeostasis in mice
-
Huang J., Zhang Y., Bersenev A., et al. Pivotal role for glycogen synthase kinase-3 in hematopoietic stem cell homeostasis in mice. J Clin Invest 2009, 119:3519-3529.
-
(2009)
J Clin Invest
, vol.119
, pp. 3519-3529
-
-
Huang, J.1
Zhang, Y.2
Bersenev, A.3
-
13
-
-
0036275356
-
Hypoxia enhances vascular cell proliferation and angiogenesis in vitro via rapamycin (mTOR)-dependent signaling
-
Humar R., Kiefer F.N., Berns H., et al. Hypoxia enhances vascular cell proliferation and angiogenesis in vitro via rapamycin (mTOR)-dependent signaling. FASEB J 2002, 16:771-780.
-
(2002)
FASEB J
, vol.16
, pp. 771-780
-
-
Humar, R.1
Kiefer, F.N.2
Berns, H.3
-
14
-
-
80052873360
-
The functions of mTOR in ischemic diseases
-
Hwang S.K., Kim H.H. The functions of mTOR in ischemic diseases. BMB Rep 2011, 44:506-511.
-
(2011)
BMB Rep
, vol.44
, pp. 506-511
-
-
Hwang, S.K.1
Kim, H.H.2
-
15
-
-
84863116629
-
Class III PI3K Vps34 plays an essential role in autophagy and in heart and liver function
-
Jaber N., Dou Z., Chen J.S., et al. Class III PI3K Vps34 plays an essential role in autophagy and in heart and liver function. Proc Natl Acad Sci USA 2012, 109:2003-2008.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 2003-2008
-
-
Jaber, N.1
Dou, Z.2
Chen, J.S.3
-
16
-
-
84055212618
-
Erythropoietin mediated bone formation is regulated by mTOR signaling
-
Kim J., Jung Y., Sun H., et al. Erythropoietin mediated bone formation is regulated by mTOR signaling. J Cell Biochem 2012, 113:220-228.
-
(2012)
J Cell Biochem
, vol.113
, pp. 220-228
-
-
Kim, J.1
Jung, Y.2
Sun, H.3
-
17
-
-
67449124604
-
Infarct size is increased in female post-MI rats treated with rapamycin
-
Lajoie C., El-Helou V., Proulx C., et al. Infarct size is increased in female post-MI rats treated with rapamycin. Can J Physiol Pharmacol 2009, 87:460-470.
-
(2009)
Can J Physiol Pharmacol
, vol.87
, pp. 460-470
-
-
Lajoie, C.1
El-Helou, V.2
Proulx, C.3
-
18
-
-
80053443687
-
Cigarette smoke components induce matrix metalloproteinase-1 in aortic endothelial cells through inhibition of mTOR signaling
-
Lemaître V., Dabo A.J., D'Armiento J. Cigarette smoke components induce matrix metalloproteinase-1 in aortic endothelial cells through inhibition of mTOR signaling. Toxicol Sci 2011, 123:542-549.
-
(2011)
Toxicol Sci
, vol.123
, pp. 542-549
-
-
Lemaître, V.1
Dabo, A.J.2
D'Armiento, J.3
-
19
-
-
76749148999
-
Oxidative stress: Biomarkers and novel therapeutic pathways
-
Maiese K., Chong Z.Z., Hou J., Shang Y.C. Oxidative stress: Biomarkers and novel therapeutic pathways. Exp Gerontol 2010, 45:217-234.
-
(2010)
Exp Gerontol
, vol.45
, pp. 217-234
-
-
Maiese, K.1
Chong, Z.Z.2
Hou, J.3
Shang, Y.C.4
-
20
-
-
60549094617
-
FoxO proteins: Cunning concepts and considerations for the cardiovascular system
-
Maiese K., Chong Z.Z., Shang Y.C., Hou J. FoxO proteins: Cunning concepts and considerations for the cardiovascular system. Clin Sci (London) 2009, 116:191-203.
-
(2009)
Clin Sci (London)
, vol.116
, pp. 191-203
-
-
Maiese, K.1
Chong, Z.Z.2
Shang, Y.C.3
Hou, J.4
-
21
-
-
11244333356
-
New avenues of exploration for erythropoietin
-
Maiese K., Li F., Chong Z.Z. New avenues of exploration for erythropoietin. JAMA 2005, 293:90-95.
-
(2005)
JAMA
, vol.293
, pp. 90-95
-
-
Maiese, K.1
Li, F.2
Chong, Z.Z.3
-
22
-
-
42649140551
-
The Wnt signaling pathway: Aging gracefully as a protectionist?
-
Maiese K., Li F., Chong Z.Z., Shang Y.C. The Wnt signaling pathway: Aging gracefully as a protectionist?. Pharmacol Ther 2008, 118:58-81.
-
(2008)
Pharmacol Ther
, vol.118
, pp. 58-81
-
-
Maiese, K.1
Li, F.2
Chong, Z.Z.3
Shang, Y.C.4
-
23
-
-
0038300674
-
Use of rapamycin slows progression of cardiac transplantation vasculopathy
-
Mancini D., Pinney S., Burkhoff D., et al. Use of rapamycin slows progression of cardiac transplantation vasculopathy. Circulation 2003, 108:48-53.
-
(2003)
Circulation
, vol.108
, pp. 48-53
-
-
Mancini, D.1
Pinney, S.2
Burkhoff, D.3
-
24
-
-
33746929488
-
MTOR inhibition induces endothelial progenitor cell death
-
Miriuka S.G., Rao V., Peterson M., et al. mTOR inhibition induces endothelial progenitor cell death. Am J Transplant 2006, 6:2069-2079.
-
(2006)
Am J Transplant
, vol.6
, pp. 2069-2079
-
-
Miriuka, S.G.1
Rao, V.2
Peterson, M.3
-
25
-
-
3242721268
-
MTOR is essential for growth and proliferation in early mouse embryos and embryonic stem cells
-
Murakami M., Ichisaka T., Maeda M., et al. mTOR is essential for growth and proliferation in early mouse embryos and embryonic stem cells. Mol Cell Biol 2004, 24:6710-6718.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 6710-6718
-
-
Murakami, M.1
Ichisaka, T.2
Maeda, M.3
-
26
-
-
77949912176
-
Phosphorylation of PRAS40 on Thr246 by PKB/AKT facilitates efficient phosphorylation of Ser183 by mTORC1
-
Nascimento E.B., Snel M., Guigas B., et al. Phosphorylation of PRAS40 on Thr246 by PKB/AKT facilitates efficient phosphorylation of Ser183 by mTORC1. Cell Signal 2010, 22:961-967.
-
(2010)
Cell Signal
, vol.22
, pp. 961-967
-
-
Nascimento, E.B.1
Snel, M.2
Guigas, B.3
-
27
-
-
80555130931
-
Single bout of running exercise changes LC3-II expression in rat cardiac muscle
-
Ogura Y., Iemitsu M., Naito H., et al. Single bout of running exercise changes LC3-II expression in rat cardiac muscle. Biochem Biophys Res Commun 2011, 414:756-760.
-
(2011)
Biochem Biophys Res Commun
, vol.414
, pp. 756-760
-
-
Ogura, Y.1
Iemitsu, M.2
Naito, H.3
-
28
-
-
69249146951
-
MTOR/S6 kinase pathway contributes to astrocyte survival during ischemia
-
Pastor M.D., García-Yébenes I., Fradejas N., et al. mTOR/S6 kinase pathway contributes to astrocyte survival during ischemia. J Biol Chem 2009, 284:22067-22078.
-
(2009)
J Biol Chem
, vol.284
, pp. 22067-22078
-
-
Pastor, M.D.1
García-Yébenes, I.2
Fradejas, N.3
-
29
-
-
77956533379
-
Extracellular protein disulfide isomerase regulates coagulation on endothelial cells through modulation of phosphatidylserine exposure
-
Popescu N.I., Lupu C., Lupu F. Extracellular protein disulfide isomerase regulates coagulation on endothelial cells through modulation of phosphatidylserine exposure. Blood 2010, 116:993-1001.
-
(2010)
Blood
, vol.116
, pp. 993-1001
-
-
Popescu, N.I.1
Lupu, C.2
Lupu, F.3
-
30
-
-
80051970950
-
FoxO3 induces reversible cardiac atrophy and autophagy in a transgenic mouse model
-
Schips T.G., Wietelmann A., Höhn K., et al. FoxO3 induces reversible cardiac atrophy and autophagy in a transgenic mouse model. Cardiovasc Res 2011, 91:587-597.
-
(2011)
Cardiovasc Res
, vol.91
, pp. 587-597
-
-
Schips, T.G.1
Wietelmann, A.2
Höhn, K.3
-
31
-
-
82155166743
-
Erythropoietin and Wnt1 govern pathways of mTOR, Apaf-1, and XIAP in inflammatory microglia
-
Shang Y.C., Chong Z.Z., Wang S., Maiese K. Erythropoietin and Wnt1 govern pathways of mTOR, Apaf-1, and XIAP in inflammatory microglia. Curr Neurovasc Res 2011, 8:270-285.
-
(2011)
Curr Neurovasc Res
, vol.8
, pp. 270-285
-
-
Shang, Y.C.1
Chong, Z.Z.2
Wang, S.3
Maiese, K.4
-
32
-
-
84860704035
-
Prevention of beta-amyloid degeneration of microglia by erythropoietin depends on Wnt1, the PI 3-K/mTOR pathway, Bad, and Bcl-xL
-
Shang Y.C., Chong Z.Z., Wang S., Maiese K. Prevention of beta-amyloid degeneration of microglia by erythropoietin depends on Wnt1, the PI 3-K/mTOR pathway, Bad, and Bcl-xL. Aging (Albany) 2012, 4:187-201.
-
(2012)
Aging (Albany)
, vol.4
, pp. 187-201
-
-
Shang, Y.C.1
Chong, Z.Z.2
Wang, S.3
Maiese, K.4
-
33
-
-
42649083704
-
Effect of rapamycin therapy on coronary artery physiology early after cardiac transplantation
-
e1-e6
-
Sinha S.S., Pham M.X., Vagelos R.H., et al. Effect of rapamycin therapy on coronary artery physiology early after cardiac transplantation. Am Heart J 2008, 155:889. e1-e6.
-
(2008)
Am Heart J
, vol.155
, pp. 889
-
-
Sinha, S.S.1
Pham, M.X.2
Vagelos, R.H.3
-
34
-
-
43249124698
-
PRAS40 and PRR5-like protein are new mTOR interactors that regulate apoptosis
-
Thedieck K., Polak P., Kim M.L., et al. PRAS40 and PRR5-like protein are new mTOR interactors that regulate apoptosis. PLoS One 2007, 2:e1217.
-
(2007)
PLoS One
, vol.2
-
-
Thedieck, K.1
Polak, P.2
Kim, M.L.3
-
35
-
-
79952843143
-
GSK-3β at the crossroads in the signalling of heart preconditioning: Implication of mTOR and Wnt pathways
-
Vigneron F., Dos Santos P., Lemoine S., et al. GSK-3β at the crossroads in the signalling of heart preconditioning: Implication of mTOR and Wnt pathways. Cardiovasc Res 2011, 90:49-56.
-
(2011)
Cardiovasc Res
, vol.90
, pp. 49-56
-
-
Vigneron, F.1
Dos Santos, P.2
Lemoine, S.3
-
36
-
-
77952289056
-
Ischemic post-conditioning reduces infarct size of the in vivo rat heart: Role of PI3-K, mTOR, GSK-3beta, and apoptosis
-
Wagner C., Tillack D., Simonis G., et al. Ischemic post-conditioning reduces infarct size of the in vivo rat heart: Role of PI3-K, mTOR, GSK-3beta, and apoptosis. Mol Cell Biochem 2010, 339:135-147.
-
(2010)
Mol Cell Biochem
, vol.339
, pp. 135-147
-
-
Wagner, C.1
Tillack, D.2
Simonis, G.3
-
37
-
-
80053330248
-
2-Methoxyestradiol attenuates autophagy activation after global ischemia
-
Xin X.Y., Pan J., Wang X.Q., et al. 2-Methoxyestradiol attenuates autophagy activation after global ischemia. Can J Neurol Sci 2011, 38:631-638.
-
(2011)
Can J Neurol Sci
, vol.38
, pp. 631-638
-
-
Xin, X.Y.1
Pan, J.2
Wang, X.Q.3
-
38
-
-
77955290360
-
MTORC1 regulates cardiac function and myocyte survival through 4E-BP1 inhibition in mice
-
Zhang D., Contu R., Latronico M.V., et al. MTORC1 regulates cardiac function and myocyte survival through 4E-BP1 inhibition in mice. J Clin Invest 2010, 120:2805-2816.
-
(2010)
J Clin Invest
, vol.120
, pp. 2805-2816
-
-
Zhang, D.1
Contu, R.2
Latronico, M.V.3
-
39
-
-
77956396096
-
Autophagy plays an important role in Sunitinib-mediated cell death in H9c2 cardiac muscle cells
-
Zhao Y., Xue T., Yang X., et al. Autophagy plays an important role in Sunitinib-mediated cell death in H9c2 cardiac muscle cells. Toxicol Appl Pharmacol 2010, 248:20-27.
-
(2010)
Toxicol Appl Pharmacol
, vol.248
, pp. 20-27
-
-
Zhao, Y.1
Xue, T.2
Yang, X.3
-
40
-
-
66049149059
-
MTOR supports long-term self-renewal and suppresses mesoderm and endoderm activities of human embryonic stem cells
-
Zhou J., Su P., Wang L., et al. mTOR supports long-term self-renewal and suppresses mesoderm and endoderm activities of human embryonic stem cells. Proc Natl Acad Sci USA 2009, 106:7840-7845.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 7840-7845
-
-
Zhou, J.1
Su, P.2
Wang, L.3
|