Effect of rapamycin therapy on coronary artery physiology early after cardiac transplantation

American Heart Journal

Volumn 155, Issue 5, 2008, Pages 889.e1-889.e6

  Sinha, Seema S ^a   Pham, Michael X ^a   Vagelos, Randall H ^a   Perlroth, Mark G ^a   Hunt, Sharon A ^a   Lee, David P ^a   Valantine, Hannah A ^a   Yeung, Alan C ^a   Fearon, William F ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOSPORIN; DACLIZUMAB; METHYLPREDNISOLONE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISONE; RAPAMYCIN; TACROLIMUS;

ADULT; ARTICLE; CARDIAC ALLOGRAFT VASCULOPATHY; CLINICAL ARTICLE; CONTROLLED STUDY; CORONARY ARTERY; CORONARY ARTERY DISEASE; CORONARY FLOW RESERVE; FEMALE; FRACTIONAL FLOW RESERVE; GUIDE WIRE; HEART TRANSPLANTATION; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; MALE; MICROCIRCULATION; MICROVASCULATURE; MULTIPLE REGRESSION; PREDICTOR VARIABLE; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE; THERMISTOR;

EID: 42649083704     PISSN: 00028703     EISSN: 10976744     Source Type: Journal    
DOI: 10.1016/j.ahj.2008.02.004     Document Type: Article

References (29)

1. D.O. Taylor L.B. Edwards M.M. Boucek Registry of the International Society for Heart and Lung Transplantation: twenty-second official adult heart transplant report–2005 J Heart Lung Transplant 24 2005 945
2. B.K. Julius J.C.H. Attenhofer G. Sutsch Incidence, progression, and functional significance of cardiac allograft vasculopathy after heart transplantation Transplantation 69 2000 847 854
3. H. Valantine Cardiac allograft vasculopathy: central role of endothelial injury leading to transplant “atheroma” Transplantation 76 2003 891 899
4. M. Kass H. Haddad Cardiac allograft vasculopathy: pathology, prevention, and treatment Curr Opin Cardiol 21 2006 132 137
5. R. Avery Viral triggers of cardiac-allograft dysfunction N Engl J Med 344 2001 1545
6. H. Valantine Role of CMV in transplant coronary artery disease and survival after heart transplantation Transpl Infect Dis 1 Suppl 1 1999 25 30
7. R.K. Avery Cardiac allograft vasculopathy N Engl J Med 349 2003 829 830
8. M. Rahmani R.P. Cruz D.J. Granville Allograft vasculopathy versus atherosclerosis Circ Res 99 2006 801 815
9. F.G. St. Goar F.J. Pinto E.L. Aldermann Intracoronary ultrasound in cardiac transplant recipients. In vivo evidence of angiographically silent intimal thickening Circulation 85 1992 979 987
10. W.F. Fearon M. Nakamura D.P. Lee Simultaneous assessment of fractional and coronary flow reserves in cardiac transplant recipients: Physiologic Investigation for Transplant Arteriopathy (PITA Study) Circulation 108 2003 1605 1610
11. W.F. Fearon A. Hirohata M. Nakamura Discordant changes in epicardial and microvascular coronary physiology after cardiac transplantation: Physiologic Investigation for Transplant Arteriopathy II (PITA II) study J Heart Lung Transplant 25 2006 765 771
12. F. Tona A.L. Caforio R. Montisci Coronary flow velocity pattern and coronary flow reserve by contrast-enhanced transthoracic echocardiography predict long-term outcome in heart transplantation Circulation 114 1 Suppl 2006 I49 I55
13. A.C. Rodrigues C. Frimm Cde F. Bacal Coronary flow reserve impairment predicts cardiac events in heart transplant patients with preserved left ventricular function Int J Cardiol 103 2005 201 206
14. D. Mancini S. Pinney D. Burkhoff Use of rapamycin slows progression of cardiac transplant vasculopathy Circulation 108 2003 48 53
15. A. Keogh M. Richardson P. Ruygrok Sirolimus in de novo heart transplant recipients reduces acute rejection and prevents coronary artery disease at two years: a randomized clinical trial Circulation 110 2004 2694 2700
16. H. Eisen E.M. Tuzcu R. Dorent Everolimus for the prevention of allograft rejection and vasculopathy in cardiac transplant recipients N Engl J Med 349 2003 847 858
17. S. Kuppahally A. Al-Khaldi D. Weisshaar Wound healing complications with de novo sirolimus versus mycophenolate mofetil-based regimen in cardiac transplant recipients Am J Transplant 6 5 Pt 1 2006 986 992
18. N. Pijls B. De Bruyne K. Peels Measurement of fractional flow reserve to assess the functional severity of coronary artery stenosis N Engl J Med 334 1996 1703 1708
19. B. De Bruyne N.H. Pijls L. Smith Coronary thermodilution to assess flow reserve: experimental validation Circulation 104 2001 2003 2006
20. N.H. Pijls B. DeBruyne L. Smith Coronary thermodilution to assess flow reserve: validation in humans Circulation 105 2002 2480 2484
21. W.F. Fearon H.M. Farouque L.B. Balsam Comparison of coronary thermodilution and Doppler velocity for assessing coronary flow reserve Circulation 108 2003 2198 2201
22. W.F. Fearon L.B. Balsam H.M. Farouque Novel index for invasively assessing the coronary microcirculation Circulation 107 2003 3129 3132
23. B. De Bruyne J. Bartunek S.U. Sys Simultaneous coronary pressure and flow velocity measurements in humans. Feasibility, reproducibility, and hemodynamic dependence of coronary flow velocity reserve, hyperemic flow versus pressure slope index, and fractional flow reserve Circulation 94 1996 1842 1849
24. M. Kern Coronary physiology revisited—practical insights from the cardiac catheterization laboratory Circulation 101 2000 1344 1351
25. K.L. Gould K. Lipscomb G.W. Hamilton Physiologic basis for assessing critical coronary stenosis. Instantaneous flow response and regional distribution during coronary hyperemia as measures of coronary flow reserve Am J Cardiol 33 1974 87 94
26. M.K. Ng A.C. Yeung W.F. Fearon Invasive assessment of the coronary microcirculation: superior reproducibility and less hemodynamic dependence of index of microcirculatory resistance compared with coronary flow reserve Circulation 113 2006 2054 2061
27. W.F. Fearon W. Aarnoudse N.H. Pijls Microvascular resistance is not influenced by epicardial coronary artery stenosis severity: experimental validation Circulation 109 2004 2269 2272
28. W. Aarnoudse W.F. Fearon G. Manoharan Epicardial stenosis severity does not affect minimal microcirculatory resistance Circulation 110 2004 2137 2142
29. K. Erinc M.H. Yamani R.C. Starling The influence of donor gender on allograft vasculopathy: evidence from intravascular ultrasound Transplant Proc 36 2004 3129 3131