-
1
-
-
43049177976
-
Triple play: Promoting neurovascular longevity with nicotinamide, WNT, and erythropoietin in diabetes mellitus
-
Maiese, K. (2008) Triple play: promoting neurovascular longevity with nicotinamide, WNT, and erythropoietin in diabetes mellitus. Biomed. Pharmacother. 62, 218-232
-
(2008)
Biomed. Pharmacother
, vol.62
, pp. 218-232
-
-
Maiese, K.1
-
2
-
-
0024973841
-
The homeotic gene fork head encodes a nuclear protein and is expressed in the terminal regions of the Drosophila embryo
-
Weigel, D., Jurgens, G., Kuttner, F., Seifert, E. and Jackle, H. (1989) The homeotic gene fork head encodes a nuclear protein and is expressed in the terminal regions of the Drosophila embryo. Cell 57, 645-658
-
(1989)
Cell
, vol.57
, pp. 645-658
-
-
Weigel, D.1
Jurgens, G.2
Kuttner, F.3
Seifert, E.4
Jackle, H.5
-
3
-
-
0342614209
-
Unified nomenclature for the winged helix/forkhead transcription factors
-
Kaestner, K. H., Knochel, W. and Martinez, D. E. (2000) Unified nomenclature for the winged helix/forkhead transcription factors. Genes Dev. 14, 142-146
-
(2000)
Genes Dev
, vol.14
, pp. 142-146
-
-
Kaestner, K.H.1
Knochel, W.2
Martinez, D.E.3
-
4
-
-
0027270989
-
Co-crystal structure of the HNF-3/fork head DNA-recognition motif resembles histone H5
-
Clark, K. L., Halay, E. D., Lai, E. and Burley, S. K. (1993) Co-crystal structure of the HNF-3/fork head DNA-recognition motif resembles histone H5. Nature 364, 412-420
-
(1993)
Nature
, vol.364
, pp. 412-420
-
-
Clark, K.L.1
Halay, E.D.2
Lai, E.3
Burley, S.K.4
-
5
-
-
35548988777
-
A winged-helix protein from Sulfolobus turreted icosahedral virus points toward stabilizing disulfide bonds in the intracellular proteins of a hyperthermophilic virus
-
Larson, E. T., Eilers, B., Menon, S. et al. (2007) A winged-helix protein from Sulfolobus turreted icosahedral virus points toward stabilizing disulfide bonds in the intracellular proteins of a hyperthermophilic virus. Virology 368, 249-261
-
(2007)
Virology
, vol.368
, pp. 249-261
-
-
Larson, E.T.1
Eilers, B.2
Menon, S.3
-
7
-
-
42749086593
-
OutFOXOing disease and disability: The therapeutic potential of targeting FoxO proteins
-
Maiese, K., Chong, Z. Z. and Shang, Y. C. (2008) OutFOXOing disease and disability: the therapeutic potential of targeting FoxO proteins. Trends Mol. Med. 14, 219-227
-
(2008)
Trends Mol. Med
, vol.14
, pp. 219-227
-
-
Maiese, K.1
Chong, Z.Z.2
Shang, Y.C.3
-
8
-
-
33746069404
-
In control of biology: Of mice, men and Foxes
-
Wijchers, P. J., Burbach, J. P. and Smidt, M. P. (2006) In control of biology: of mice, men and Foxes. Biochem. J. 397, 233-246
-
(2006)
Biochem. J
, vol.397
, pp. 233-246
-
-
Wijchers, P.J.1
Burbach, J.P.2
Smidt, M.P.3
-
9
-
-
0030657540
-
Daf-16: An HNF-3/ forkhead family member that can function to double the life-span of Caenorhabditis elegans
-
Lin, K., Dorman, J. B., Rodan, A. and Kenyon, C. (1997) Daf-16: an HNF-3/ forkhead family member that can function to double the life-span of Caenorhabditis elegans. Science 278, 1319-1322
-
(1997)
Science
, vol.278
, pp. 1319-1322
-
-
Lin, K.1
Dorman, J.B.2
Rodan, A.3
Kenyon, C.4
-
10
-
-
0030659557
-
The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans
-
Ogg, S., Paradis, S., Gottlieb, S. et al. (1997) The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans. Nature 389, 994-999
-
(1997)
Nature
, vol.389
, pp. 994-999
-
-
Ogg, S.1
Paradis, S.2
Gottlieb, S.3
-
11
-
-
36448967502
-
Sly as a FOXO': New paths with Forkhead signaling in the brain
-
Maiese, K., Chong, Z. Z. and Shang, Y. C. (2007) 'Sly as a FOXO': new paths with Forkhead signaling in the brain. Curr. Neurovasc. Res. 4, 295-302
-
(2007)
Curr. Neurovasc. Res
, vol.4
, pp. 295-302
-
-
Maiese, K.1
Chong, Z.Z.2
Shang, Y.C.3
-
12
-
-
0034661826
-
Identification of the differential distribution patterns of mRNAs and consensus binding sequences for mouse DAF-16 homologues
-
Furuyama, T., Nakazawa, T., Nakano, I. and Mori, N. (2000) Identification of the differential distribution patterns of mRNAs and consensus binding sequences for mouse DAF-16 homologues. Biochem. J. 349, 629-634
-
(2000)
Biochem. J
, vol.349
, pp. 629-634
-
-
Furuyama, T.1
Nakazawa, T.2
Nakano, I.3
Mori, N.4
-
13
-
-
0035019007
-
Identification and characterization of members of the FKHR (FOX O) subclass of winged-helix transcription factors in the mouse
-
Biggs, III, W. H., Cavenee, W. K. and Arden, K. C. (2001) Identification and characterization of members of the FKHR (FOX O) subclass of winged-helix transcription factors in the mouse. Mamm. Genome 12, 416-425
-
(2001)
Mamm. Genome
, vol.12
, pp. 416-425
-
-
Biggs III, W.H.1
Cavenee, W.K.2
Arden, K.C.3
-
14
-
-
30444442827
-
Spatial and temporal expression of FoxO transcription factors in the developing and adult murine brain
-
Hoekman, M. F., Jacobs, F. M., Smidt, M. P. and Burbach, J. P. (2006) Spatial and temporal expression of FoxO transcription factors in the developing and adult murine brain. Gene Expr. Patterns 6, 134-140
-
(2006)
Gene Expr. Patterns
, vol.6
, pp. 134-140
-
-
Hoekman, M.F.1
Jacobs, F.M.2
Smidt, M.P.3
Burbach, J.P.4
-
15
-
-
36549065662
-
FoxO tumor suppressors and BCR-ABL-induced leukemia: A matter of evasion of apoptosis
-
Jagani, Z., Singh, A. and Khosravi-Far, R. (2008) FoxO tumor suppressors and BCR-ABL-induced leukemia: a matter of evasion of apoptosis. Biochim. Biophys. Acta 1785, 63-84
-
(2008)
Biochim. Biophys. Acta
, vol.1785
, pp. 63-84
-
-
Jagani, Z.1
Singh, A.2
Khosravi-Far, R.3
-
16
-
-
35548930209
-
The emerging roles of forkhead box (Fox) proteins in cancer
-
Myatt, S. S. and Lam, E. W. (2007) The emerging roles of forkhead box (Fox) proteins in cancer. Nat. Rev. Cancer. 7, 847-859
-
(2007)
Nat. Rev. Cancer
, vol.7
, pp. 847-859
-
-
Myatt, S.S.1
Lam, E.W.2
-
17
-
-
34249281690
-
Stressing the role of FoxO proteins in lifespan and disease
-
van der Horst, A. and Burgering, B. M. (2007) Stressing the role of FoxO proteins in lifespan and disease. Nat. Rev. Mol. Cell. Biol. 8, 440-450
-
(2007)
Nat. Rev. Mol. Cell. Biol
, vol.8
, pp. 440-450
-
-
van der Horst, A.1
Burgering, B.M.2
-
18
-
-
0037016065
-
Erythropoietin is a novel vascular protectant through activation of Akt1 and mitochondrial modulation of cysteine proteases
-
Chong, Z. Z., Kang, J. Q. and Maiese, K. (2002) Erythropoietin is a novel vascular protectant through activation of Akt1 and mitochondrial modulation of cysteine proteases. Circulation 106, 2973-2979
-
(2002)
Circulation
, vol.106
, pp. 2973-2979
-
-
Chong, Z.Z.1
Kang, J.Q.2
Maiese, K.3
-
19
-
-
29044433048
-
Erythropoietin requires NF-κB and its nuclear translocation to prevent early and late apoptotic neuronal injury during β-amyloid toxicity
-
Chong, Z. Z., Li, F. and Maiese, K. (2005) Erythropoietin requires NF-κB and its nuclear translocation to prevent early and late apoptotic neuronal injury during β-amyloid toxicity. Curr. Neurovasc. Res. 2, 387-399
-
(2005)
Curr. Neurovasc. Res
, vol.2
, pp. 387-399
-
-
Chong, Z.Z.1
Li, F.2
Maiese, K.3
-
20
-
-
34147100616
-
Cellular demise and inflammatory microglial activation during β-amyloid toxicity are governed by Wnt1 and canonical signaling pathways
-
Chong, Z. Z., Li, F. and Maiese, K. (2007) Cellular demise and inflammatory microglial activation during β-amyloid toxicity are governed by Wnt1 and canonical signaling pathways. Cell. Signalling 19, 1150-1162
-
(2007)
Cell. Signalling
, vol.19
, pp. 1150-1162
-
-
Chong, Z.Z.1
Li, F.2
Maiese, K.3
-
21
-
-
37349123107
-
Erythropoietin protects against doxorubicin-induced cardiomyopathy via a phosphatidylinositol 3-kinase-dependent pathway
-
Kim, K. H., Oudit, G. Y. and Backx, P. H. (2008) Erythropoietin protects against doxorubicin-induced cardiomyopathy via a phosphatidylinositol 3-kinase-dependent pathway. J. Pharmacol. Exp. Ther. 324, 160-169
-
(2008)
J. Pharmacol. Exp. Ther
, vol.324
, pp. 160-169
-
-
Kim, K.H.1
Oudit, G.Y.2
Backx, P.H.3
-
22
-
-
0033560896
-
Direct control of the Forkhead transcription factor AFX by protein kinase B
-
Kops, G. J., de Ruiter, N. D., De Vries-Smits, A. M., Powell, D. R., Bos, J. L. and Burgering, B. M. (1999) Direct control of the Forkhead transcription factor AFX by protein kinase B. Nature 398, 630-634
-
(1999)
Nature
, vol.398
, pp. 630-634
-
-
Kops, G.J.1
de Ruiter, N.D.2
De Vries-Smits, A.M.3
Powell, D.R.4
Bos, J.L.5
Burgering, B.M.6
-
23
-
-
0039425278
-
Negative regulation of the forkhead transcription factor FKHR by Akt
-
Tang, E. D., Nunez, G., Barr, F. G. and Guan, K. L. (1999) Negative regulation of the forkhead transcription factor FKHR by Akt. J. Biol. Chem. 274, 16741-16746
-
(1999)
J. Biol. Chem
, vol.274
, pp. 16741-16746
-
-
Tang, E.D.1
Nunez, G.2
Barr, F.G.3
Guan, K.L.4
-
24
-
-
0033595011
-
Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1
-
Biggs, III, W. H., Meisenhelder, J., Hunter, T., Cavenee, W. K. and Arden, K. C. (1999) Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1. Proc. Natl. Acad. Sci. U.S.A. 96, 7421-7426
-
(1999)
Proc. Natl. Acad. Sci. U.S.A
, vol.96
, pp. 7421-7426
-
-
Biggs III, W.H.1
Meisenhelder, J.2
Hunter, T.3
Cavenee, W.K.4
Arden, K.C.5
-
25
-
-
34047234725
-
Erythropoietin involves the phosphatidylinositol 3-kinase pathway, 14-13-3 protein and FOXO3a nuclear trafficking to preserve endothelial cell integrity
-
Chong, Z. Z. and Maiese, K. (2007) Erythropoietin involves the phosphatidylinositol 3-kinase pathway, 14-13-3 protein and FOXO3a nuclear trafficking to preserve endothelial cell integrity. Br. J. Pharmacol. 150, 839-850
-
(2007)
Br. J. Pharmacol
, vol.150
, pp. 839-850
-
-
Chong, Z.Z.1
Maiese, K.2
-
26
-
-
11244333356
-
New avenues of exploration for erythropoietin
-
Maiese, K., Li, F. and Chong, Z. Z. (2005) New avenues of exploration for erythropoietin. JAMA, J. Am. Med. Assoc. 293, 90-95
-
(2005)
JAMA, J. Am. Med. Assoc
, vol.293
, pp. 90-95
-
-
Maiese, K.1
Li, F.2
Chong, Z.Z.3
-
27
-
-
2442461973
-
L and caspase 1, 3, and 9
-
L and caspase 1, 3, and 9. Exp. Cell Res. 296, 196-207
-
(2004)
Exp. Cell Res
, vol.296
, pp. 196-207
-
-
Chong, Z.Z.1
Kang, J.Q.2
Maiese, K.3
-
28
-
-
34748831102
-
The Src homology 2 domain tyrosine phosphatases SHP-1 and SHP-2: Diversified control of cell growth, inflammation, and injury
-
Chong, Z. Z. and Maiese, K. (2007) The Src homology 2 domain tyrosine phosphatases SHP-1 and SHP-2: diversified control of cell growth, inflammation, and injury. Histol. Histopathol. 22, 1251-1267
-
(2007)
Histol. Histopathol
, vol.22
, pp. 1251-1267
-
-
Chong, Z.Z.1
Maiese, K.2
-
29
-
-
0037338625
-
L, cytochrome c, and caspase-9 form the critical elements for cerebral vascular protection by erythropoietin
-
L, cytochrome c, and caspase-9 form the critical elements for cerebral vascular protection by erythropoietin. J. Cereb. Blood Flow Metab. 23, 320-330
-
(2003)
J. Cereb. Blood Flow Metab
, vol.23
, pp. 320-330
-
-
Chong, Z.Z.1
Kang, J.Q.2
Maiese, K.3
-
30
-
-
0037365196
-
Erythropoietin fosters both intrinsic and extrinsic neuronal protection through modulation of microglia, Akt1, Bad, and caspase-mediated pathways
-
Chong, Z. Z., Kang, J. Q. and Maiese, K. (2003) Erythropoietin fosters both intrinsic and extrinsic neuronal protection through modulation of microglia, Akt1, Bad, and caspase-mediated pathways. Br. J. Pharmacol. 138, 1107-1118
-
(2003)
Br. J. Pharmacol
, vol.138
, pp. 1107-1118
-
-
Chong, Z.Z.1
Kang, J.Q.2
Maiese, K.3
-
31
-
-
1542409923
-
Essential cellular regulatory elements of oxidative stress in early and late phases of apoptosis in the central nervous system
-
Chong, Z. Z., Kang, J. Q. and Maiese, K. (2004) Essential cellular regulatory elements of oxidative stress in early and late phases of apoptosis in the central nervous system. Antioxid. Redox Signaling 6, 277-287
-
(2004)
Antioxid. Redox Signaling
, vol.6
, pp. 277-287
-
-
Chong, Z.Z.1
Kang, J.Q.2
Maiese, K.3
-
32
-
-
33646775275
-
Group I metabotropic receptor neuroprotection requires Akt and its substrates that govern FOXO3a, Bim, and β-catenin during oxidative stress
-
Chong, Z. Z., Li, F. and Maiese, K. (2006) Group I metabotropic receptor neuroprotection requires Akt and its substrates that govern FOXO3a, Bim, and β-catenin during oxidative stress. Curr. Neurovasc. Res. 3, 107-117
-
(2006)
Curr. Neurovasc. Res
, vol.3
, pp. 107-117
-
-
Chong, Z.Z.1
Li, F.2
Maiese, K.3
-
33
-
-
3042730681
-
+ precursor nicotinamide governs neuronal survival during oxidative stress through protein kinase B coupled to FOXO3a and mitochondrial membrane potential
-
+ precursor nicotinamide governs neuronal survival during oxidative stress through protein kinase B coupled to FOXO3a and mitochondrial membrane potential. J. Cereb. Blood Flow Metab. 24, 728-743
-
(2004)
J. Cereb. Blood Flow Metab
, vol.24
, pp. 728-743
-
-
Chong, Z.Z.1
Lin, S.H.2
Maiese, K.3
-
34
-
-
33847077943
-
FKHRL1-mediated expression of Noxa and Bim induces apoptosis via the mitochondria in neuroblastoma cells
-
Obexer, P., Geiger, K., Ambros, P. F., Meister, B. and Ausserlechner, M. J. (2007) FKHRL1-mediated expression of Noxa and Bim induces apoptosis via the mitochondria in neuroblastoma cells. Cell Death Differ. 14, 534-547
-
(2007)
Cell Death Differ
, vol.14
, pp. 534-547
-
-
Obexer, P.1
Geiger, K.2
Ambros, P.F.3
Meister, B.4
Ausserlechner, M.J.5
-
35
-
-
0038362751
-
Akt activation promotes degradation of tuberin and FOXO3a via the proteasome
-
Plas, D. R. and Thompson, C. B. (2003) Akt activation promotes degradation of tuberin and FOXO3a via the proteasome. J. Biol. Chem. 278, 12361-12366
-
(2003)
J. Biol. Chem
, vol.278
, pp. 12361-12366
-
-
Plas, D.R.1
Thompson, C.B.2
-
36
-
-
33646934067
-
A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life span
-
Lehtinen, M. K., Yuan, Z., Boag, P. R. et al. (2006) A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life span. Cell 125, 987-1001
-
(2006)
Cell
, vol.125
, pp. 987-1001
-
-
Lehtinen, M.K.1
Yuan, Z.2
Boag, P.R.3
-
37
-
-
39849092395
-
Differential cleavage of Mst1 by caspase-7/-3 is responsible for TRAIL-induced activation of the MAPK superfamily
-
Song, J. J. and Lee, Y. J. (2008) Differential cleavage of Mst1 by caspase-7/-3 is responsible for TRAIL-induced activation of the MAPK superfamily. Cell. Signalling 20, 892-906
-
(2008)
Cell. Signalling
, vol.20
, pp. 892-906
-
-
Song, J.J.1
Lee, Y.J.2
-
38
-
-
18844434370
-
Oxidative stress in the brain: Novel cellular targets that govern survival during neurodegenerative disease
-
Chong, Z. Z., Li, F. and Maiese, K. (2005) Oxidative stress in the brain: novel cellular targets that govern survival during neurodegenerative disease. Prog. Neurobiol. 75, 207-246
-
(2005)
Prog. Neurobiol
, vol.75
, pp. 207-246
-
-
Chong, Z.Z.1
Li, F.2
Maiese, K.3
-
39
-
-
41449110023
-
Diabetic stress: New triumphs and challenges to maintain vascular longevity
-
Maiese, K. (2008) Diabetic stress: new triumphs and challenges to maintain vascular longevity. Expert Rev. Cardiovasc. Ther. 6, 281-284
-
(2008)
Expert Rev. Cardiovasc. Ther
, vol.6
, pp. 281-284
-
-
Maiese, K.1
-
40
-
-
0038061606
-
Nicotinamide: Necessary nutrient emerges as a novel cytoprotectant for the brain
-
Maiese, K. and Chong, Z. Z. (2003) Nicotinamide: necessary nutrient emerges as a novel cytoprotectant for the brain. Trends Pharmacol. Sci. 24, 228-232
-
(2003)
Trends Pharmacol. Sci
, vol.24
, pp. 228-232
-
-
Maiese, K.1
Chong, Z.Z.2
-
41
-
-
41749101585
-
Nicotinamide and 1-methylnicotinamide reduce homocysteine neurotoxicity in primary cultures of rat cerebellar granule cells
-
Slomka, M., Zieminska, E. and Lazarewicz, J. (2008) Nicotinamide and 1-methylnicotinamide reduce homocysteine neurotoxicity in primary cultures of rat cerebellar granule cells. Acta Neurobiol. Exp. 68, 1-9
-
(2008)
Acta Neurobiol. Exp
, vol.68
, pp. 1-9
-
-
Slomka, M.1
Zieminska, E.2
Lazarewicz, J.3
-
42
-
-
45249120614
-
Erythropoietin and oxidative stress
-
Maiese, K., Chong, Z. Z., Hou, J. and Shang, Y. C. (2008) Erythropoietin and oxidative stress. Curr. Neurovasc. Res. 5, 125-142
-
(2008)
Curr. Neurovasc. Res
, vol.5
, pp. 125-142
-
-
Maiese, K.1
Chong, Z.Z.2
Hou, J.3
Shang, Y.C.4
-
43
-
-
37349057933
-
Forkhead transcription factor FOXO subfamily is essential for reactive oxygen species-induced apoptosis
-
Nakamura, T. and Sakamoto, K. (2007) Forkhead transcription factor FOXO subfamily is essential for reactive oxygen species-induced apoptosis. Mol. Cell. Endocrinol. 281, 47-55
-
(2007)
Mol. Cell. Endocrinol
, vol.281
, pp. 47-55
-
-
Nakamura, T.1
Sakamoto, K.2
-
44
-
-
12944294341
-
Foxo3a induces motoneuron death through the Fas pathway in cooperation with JNK
-
Barthelemy, C., Henderson, C. E. and Pettmann, B. (2004) Foxo3a induces motoneuron death through the Fas pathway in cooperation with JNK. BMC Neurosci. 5, 48
-
(2004)
BMC Neurosci
, vol.5
, pp. 48
-
-
Barthelemy, C.1
Henderson, C.E.2
Pettmann, B.3
-
45
-
-
33745163907
-
Regulation of transactivation-independent proapoptotic activity of p53 by FOXO3a
-
You, H., Yamamoto, K. and Mak, T. W. (2006) Regulation of transactivation-independent proapoptotic activity of p53 by FOXO3a. Proc. Natl. Acad. Sci. U.S.A. 103, 9051-9056
-
(2006)
Proc. Natl. Acad. Sci. U.S.A
, vol.103
, pp. 9051-9056
-
-
You, H.1
Yamamoto, K.2
Mak, T.W.3
-
46
-
-
33645993568
-
Estradiol prevents the focal cerebral ischemic injury-induced decrease of forkhead transcription factors phosphorylation
-
Won, C. K., Ji, H. H. and Koh, P. O. (2006) Estradiol prevents the focal cerebral ischemic injury-induced decrease of forkhead transcription factors phosphorylation. Neurosci. Lett. 398, 39-43
-
(2006)
Neurosci. Lett
, vol.398
, pp. 39-43
-
-
Won, C.K.1
Ji, H.H.2
Koh, P.O.3
-
47
-
-
38049134474
-
Identification of the prosurvival activity of nerve growth factor on cardiac myocytes
-
Caporali, A., Sala-Newby, G. B., Meloni, M. et al. (2008) Identification of the prosurvival activity of nerve growth factor on cardiac myocytes. Cell Death Differ. 15, 299-311
-
(2008)
Cell Death Differ
, vol.15
, pp. 299-311
-
-
Caporali, A.1
Sala-Newby, G.B.2
Meloni, M.3
-
48
-
-
26944461217
-
Transcriptional feedback control of insulin receptor by dFOXO/FOXO1
-
Puig, O. and Tjian, R. (2005) Transcriptional feedback control of insulin receptor by dFOXO/FOXO1. Genes Dev. 19, 2435-2446
-
(2005)
Genes Dev
, vol.19
, pp. 2435-2446
-
-
Puig, O.1
Tjian, R.2
-
49
-
-
33846419112
-
FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress
-
Tothova, Z., Kollipara, R., Huntly, B. J. et al. (2007) FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress. Cell 128, 325-339
-
(2007)
Cell
, vol.128
, pp. 325-339
-
-
Tothova, Z.1
Kollipara, R.2
Huntly, B.J.3
-
50
-
-
39449118273
-
Exercise training promotes SIRT1 activity in aged rats
-
Ferrara, N., Rinaldi, B., Corbi, G. et al. (2007) Exercise training promotes SIRT1 activity in aged rats. Rejuvenation Res. 11, 139-150
-
(2007)
Rejuvenation Res
, vol.11
, pp. 139-150
-
-
Ferrara, N.1
Rinaldi, B.2
Corbi, G.3
-
51
-
-
29844447503
-
Winding through the WNT pathway during cellular development and demise
-
Li, F., Chong, Z. Z. and Maiese, K. (2006) Winding through the WNT pathway during cellular development and demise. Histol. Histopathol. 21, 103-124
-
(2006)
Histol. Histopathol
, vol.21
, pp. 103-124
-
-
Li, F.1
Chong, Z.Z.2
Maiese, K.3
-
52
-
-
42649140551
-
The Wnt signaling pathway: Aging gracefully as a protectionist?
-
Maiese, K., Li, F., Chong, Z. Z. and Shang, Y. C. (2008) The Wnt signaling pathway: aging gracefully as a protectionist? Pharmacol. Ther. 118, 58-81
-
(2008)
Pharmacol. Ther
, vol.118
, pp. 58-81
-
-
Maiese, K.1
Li, F.2
Chong, Z.Z.3
Shang, Y.C.4
-
53
-
-
18544372447
-
Phosphorylation of p66Shc and forkhead proteins mediates Aβ toxicity
-
Smith, W. W., Norton, D. D., Gorospe, M. et al. (2005) Phosphorylation of p66Shc and forkhead proteins mediates Aβ toxicity. J. Cell Biol. 169, 331-339
-
(2005)
J. Cell Biol
, vol.169
, pp. 331-339
-
-
Smith, W.W.1
Norton, D.D.2
Gorospe, M.3
-
54
-
-
44049092138
-
Interaction of FOXO with β-catenin inhibits β-catenin/t cell factor activity
-
Hoogeboom, D., Essers, M. A., Polderman, P. E., Voets, E., Smits, L. M. and Burgering, B. M. (2008) Interaction of FOXO with β-catenin inhibits β-catenin/t cell factor activity. J. Biol. Chem. 283, 9224-9230
-
(2008)
J. Biol. Chem
, vol.283
, pp. 9224-9230
-
-
Hoogeboom, D.1
Essers, M.A.2
Polderman, P.E.3
Voets, E.4
Smits, L.M.5
Burgering, B.M.6
-
55
-
-
22744440212
-
Phosphatidylinositol 3-kinase-Akt pathway plays a critical role in early cardiomyogenesis by regulating canonical Wnt signaling
-
Naito, A. T., Akazawa, H., Takano, H. et al. (2005) Phosphatidylinositol 3-kinase-Akt pathway plays a critical role in early cardiomyogenesis by regulating canonical Wnt signaling. Circ. Res. 97, 144-151
-
(2005)
Circ. Res
, vol.97
, pp. 144-151
-
-
Naito, A.T.1
Akazawa, H.2
Takano, H.3
-
56
-
-
40849086204
-
Raves and risks for erythropoietin
-
Maiese, K., Chong, Z. Z. and Shang, Y. C. (2008) Raves and risks for erythropoietin. Cytokine Growth Factor Rev. 19, 145-155
-
(2008)
Cytokine Growth Factor Rev
, vol.19
, pp. 145-155
-
-
Maiese, K.1
Chong, Z.Z.2
Shang, Y.C.3
-
57
-
-
1542267804
-
Disruption of forkhead transcription factor (FOXO) family members in mice reveals their functional diversification
-
Hosaka, T., Biggs, III, W. H., Tieu, D. et al. (2004) Disruption of forkhead transcription factor (FOXO) family members in mice reveals their functional diversification. Proc. Natl. Acad. Sci. U.S.A. 101, 2975-2980
-
(2004)
Proc. Natl. Acad. Sci. U.S.A
, vol.101
, pp. 2975-2980
-
-
Hosaka, T.1
Biggs III, W.H.2
Tieu, D.3
-
58
-
-
4544227785
-
Abnormal angiogenesis in Foxo1 (Fkhr)-deficient mice
-
Furuyama, T., Kitayama, K., Shimoda, Y. et al. (2004) Abnormal angiogenesis in Foxo1 (Fkhr)-deficient mice. J. Biol. Chem. 279, 34741-34749
-
(2004)
J. Biol. Chem
, vol.279
, pp. 34741-34749
-
-
Furuyama, T.1
Kitayama, K.2
Shimoda, Y.3
-
59
-
-
41449088342
-
Regulation of cardiomyocyte proliferation and myocardial growth during development by FOXO transcription factors
-
Evans-Anderson, H. J., Alfieri, C. M. and Yutzey, K. E. (2008) Regulation of cardiomyocyte proliferation and myocardial growth during development by FOXO transcription factors. Circ. Res. 102, 686-694
-
(2008)
Circ. Res
, vol.102
, pp. 686-694
-
-
Evans-Anderson, H.J.1
Alfieri, C.M.2
Yutzey, K.E.3
-
60
-
-
36049026136
-
Atrogin-1 inhibits Akt-dependent cardiac hypertrophy in mice via ubiquitin-dependent coactivation of Forkhead proteins
-
Li, H. H., Willis, M. S., Lockyer, P. et al. (2007) Atrogin-1 inhibits Akt-dependent cardiac hypertrophy in mice via ubiquitin-dependent coactivation of Forkhead proteins. J. Clin. Invest. 117, 3211-3223
-
(2007)
J. Clin. Invest
, vol.117
, pp. 3211-3223
-
-
Li, H.H.1
Willis, M.S.2
Lockyer, P.3
-
61
-
-
23844491841
-
Forkhead transcription factors inhibit vascular smooth muscle cell proliferation and neointimal hyperplasia
-
Abid, M. R., Yano, K., Guo, S. et al. (2005) Forkhead transcription factors inhibit vascular smooth muscle cell proliferation and neointimal hyperplasia. J. Biol. Chem. 280, 29864-29873
-
(2005)
J. Biol. Chem
, vol.280
, pp. 29864-29873
-
-
Abid, M.R.1
Yano, K.2
Guo, S.3
-
62
-
-
22944451474
-
Phenotypic modulation of smooth muscle cells through interaction of Foxo4 and myocardin
-
Liu, Z. P., Wang, Z., Yanagisawa, H. and Olson, E. N. (2005) Phenotypic modulation of smooth muscle cells through interaction of Foxo4 and myocardin. Dev. Cell 9, 261-270
-
(2005)
Dev. Cell
, vol.9
, pp. 261-270
-
-
Liu, Z.P.1
Wang, Z.2
Yanagisawa, H.3
Olson, E.N.4
-
63
-
-
34147195312
-
FoxO4 regulates tumor necrosis factor α-directed smooth muscle cell migration by activating matrix metalloproteinase 9 gene transcription
-
Li, H., Liang, J., Castrillon, D. H., DePinho, R. A., Olson, E. N. and Liu, Z. P. (2007) FoxO4 regulates tumor necrosis factor α-directed smooth muscle cell migration by activating matrix metalloproteinase 9 gene transcription. Mol. Cell. Biol. 27, 2676-2686
-
(2007)
Mol. Cell. Biol
, vol.27
, pp. 2676-2686
-
-
Li, H.1
Liang, J.2
Castrillon, D.H.3
DePinho, R.A.4
Olson, E.N.5
Liu, Z.P.6
-
64
-
-
37349130603
-
Flow-dependent regulation of angiopoietin-2
-
Goettsch, W., Gryczka, C., Korff, T. et al. (2008) Flow-dependent regulation of angiopoietin-2. J. Cell. Physiol. 214, 491-503
-
(2008)
J. Cell. Physiol
, vol.214
, pp. 491-503
-
-
Goettsch, W.1
Gryczka, C.2
Korff, T.3
-
66
-
-
0042413919
-
Mechanosensitive p27Kip1 regulation and cell cycle entry in vascular smooth muscle cells
-
Sedding, D. G., Seay, U., Fink, L. et al. (2003) Mechanosensitive p27Kip1 regulation and cell cycle entry in vascular smooth muscle cells. Circulation 108, 616-622
-
(2003)
Circulation
, vol.108
, pp. 616-622
-
-
Sedding, D.G.1
Seay, U.2
Fink, L.3
-
67
-
-
33748745399
-
Transcriptional genomics associates FOX transcription factors with human heart failure
-
Hannenhalli, S., Putt, M. E., Gilmore, J. M. et al. (2006) Transcriptional genomics associates FOX transcription factors with human heart failure. Circulation 114, 1269-1276
-
(2006)
Circulation
, vol.114
, pp. 1269-1276
-
-
Hannenhalli, S.1
Putt, M.E.2
Gilmore, J.M.3
-
68
-
-
43449127489
-
Erythropoietin: Elucidating new cellular targets that broaden therapeutic strategies
-
Maiese, K., Chong, Z. Z., Li, F. and Shang, Y. C. (2008) Erythropoietin: elucidating new cellular targets that broaden therapeutic strategies. Prog. Neurobiol. 85, 194-213
-
(2008)
Prog. Neurobiol
, vol.85
, pp. 194-213
-
-
Maiese, K.1
Chong, Z.Z.2
Li, F.3
Shang, Y.C.4
-
69
-
-
35548932785
-
Active FKHRL1 overcomes imatinib resistance in chronic myelogenous leukemia-derived cell lines via the production of tumor necrosis factor-related apoptosis-inducing ligand
-
Kikuchi, S., Nagai, T., Kunitama, M., Kirito, K., Ozawa, K. and Komatsu, N. (2007) Active FKHRL1 overcomes imatinib resistance in chronic myelogenous leukemia-derived cell lines via the production of tumor necrosis factor-related apoptosis-inducing ligand. Cancer Sci. 98, 1949-1958
-
(2007)
Cancer Sci
, vol.98
, pp. 1949-1958
-
-
Kikuchi, S.1
Nagai, T.2
Kunitama, M.3
Kirito, K.4
Ozawa, K.5
Komatsu, N.6
-
70
-
-
34247898772
-
E2F-1 regulates expression of FOXO1 and FOXO3a
-
Nowak, K., Killmer, K., Gessner, C. and Lutz, W. (2007) E2F-1 regulates expression of FOXO1 and FOXO3a. Biochim. Biophys. Acta 1769, 244-252
-
(2007)
Biochim. Biophys. Acta
, vol.1769
, pp. 244-252
-
-
Nowak, K.1
Killmer, K.2
Gessner, C.3
Lutz, W.4
-
71
-
-
12144290563
-
Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase
-
Brunet, A., Sweeney, L. B., Sturgill, J. F. et al. (2004) Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase. Science 303, 2011-2015
-
(2004)
Science
, vol.303
, pp. 2011-2015
-
-
Brunet, A.1
Sweeney, L.B.2
Sturgill, J.F.3
-
72
-
-
33846295218
-
FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis
-
Paik, J. H., Kollipara, R., Chu, G. et al. (2007) FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis. Cell 128, 309-323
-
(2007)
Cell
, vol.128
, pp. 309-323
-
-
Paik, J.H.1
Kollipara, R.2
Chu, G.3
-
74
-
-
35148859334
-
Trastuzumab-resistant HER2-driven breast cancer cells are sensitive to epigallocatechin-3 gallate
-
Eddy, S. F., Kane, S. E. and Sonenshein, G. E. (2007) Trastuzumab-resistant HER2-driven breast cancer cells are sensitive to epigallocatechin-3 gallate. Cancer Res. 67, 9018-9023
-
(2007)
Cancer Res
, vol.67
, pp. 9018-9023
-
-
Eddy, S.F.1
Kane, S.E.2
Sonenshein, G.E.3
-
75
-
-
34547135737
-
Regulation of FOXO3a /β-catenin/GSK-3β signaling by 3,3′-diindolylmethane contributes to inhibition of cell proliferation and induction of apoptosis in prostate cancer cells
-
Li, Y., Wang, Z., Kong, D. et al. (2007) Regulation of FOXO3a /β-catenin/GSK-3β signaling by 3,3′-diindolylmethane contributes to inhibition of cell proliferation and induction of apoptosis in prostate cancer cells. J. Biol. Chem. 282, 21542-21550
-
(2007)
J. Biol. Chem
, vol.282
, pp. 21542-21550
-
-
Li, Y.1
Wang, Z.2
Kong, D.3
-
76
-
-
34347357584
-
Induction of Mxi1-SRα by FOXO3a contributes to repression of Myc-dependent gene expression
-
Delpuech, O., Griffiths, B., East, P. et al. (2007) Induction of Mxi1-SRα by FOXO3a contributes to repression of Myc-dependent gene expression. Mol. Cell. Biol. 27, 4917-4930
-
(2007)
Mol. Cell. Biol
, vol.27
, pp. 4917-4930
-
-
Delpuech, O.1
Griffiths, B.2
East, P.3
-
77
-
-
35948946952
-
Homeostatic chemokines increase survival of B-chronic lymphocytic leukemia cells through inactivation of transcription factor FOXO3a
-
Ticchioni, M., Essafi, M., Jeandel, P. Y. et al. (2007) Homeostatic chemokines increase survival of B-chronic lymphocytic leukemia cells through inactivation of transcription factor FOXO3a. Oncogene 26, 7081-7091
-
(2007)
Oncogene
, vol.26
, pp. 7081-7091
-
-
Ticchioni, M.1
Essafi, M.2
Jeandel, P.Y.3
-
78
-
-
25844486505
-
Induction of androgen receptor expression by phosphatidylinositol 3-kinase/Akt downstream substrate, FOXO3a, and their roles in apoptosis of LNCaP prostate cancer cells
-
Yang, L., Xie, S., Jamaluddin, M. S. et al. (2005) Induction of androgen receptor expression by phosphatidylinositol 3-kinase/Akt downstream substrate, FOXO3a, and their roles in apoptosis of LNCaP prostate cancer cells. J. Biol. Chem. 280, 33558-33565
-
(2005)
J. Biol. Chem
, vol.280
, pp. 33558-33565
-
-
Yang, L.1
Xie, S.2
Jamaluddin, M.S.3
-
79
-
-
12144290140
-
Inhibition of phosphorylation of a forkhead transcription factor sensitizes human ovarian cancer cells to cisplatin
-
Arimoto-Ishida, E., Ohmichi, M., Mabuchi, S. et al. (2004) Inhibition of phosphorylation of a forkhead transcription factor sensitizes human ovarian cancer cells to cisplatin. Endocrinology 145, 2014-2022
-
(2004)
Endocrinology
, vol.145
, pp. 2014-2022
-
-
Arimoto-Ishida, E.1
Ohmichi, M.2
Mabuchi, S.3
-
80
-
-
35348976537
-
Molecular pathogenesis of adult brain tumors and the role of stem cells
-
Sauvageot, C. M., Kesari, S. and Stiles, C. D. (2007) Molecular pathogenesis of adult brain tumors and the role of stem cells. Neurol. Clin. 25, 891-924
-
(2007)
Neurol. Clin
, vol.25
, pp. 891-924
-
-
Sauvageot, C.M.1
Kesari, S.2
Stiles, C.D.3
-
81
-
-
34249882777
-
Foxo3a is essential for maintenance of the hematopoietic stem cell pool
-
Miyamoto, K., Araki, K. Y., Naka, K. et al. (2007) Foxo3a is essential for maintenance of the hematopoietic stem cell pool. Cell Stem Cells 1, 101-112
-
(2007)
Cell Stem Cells
, vol.1
, pp. 101-112
-
-
Miyamoto, K.1
Araki, K.Y.2
Naka, K.3
-
82
-
-
40449087690
-
The non-haematopoietic biological effects of erythropoietin
-
Arcasoy, M. O. (2008) The non-haematopoietic biological effects of erythropoietin. Br. J. Haematol. 141, 14-31
-
(2008)
Br. J. Haematol
, vol.141
, pp. 14-31
-
-
Arcasoy, M.O.1
-
83
-
-
38849150980
-
Early high-dose erythropoietin therapy and hypothermia after out-of-hospital cardiac arrest: A matched control study
-
Cariou, A., Claessens, Y. E., Pene, F. et al. (2008) Early high-dose erythropoietin therapy and hypothermia after out-of-hospital cardiac arrest: a matched control study. Resuscitation 76, 397-404
-
(2008)
Resuscitation
, vol.76
, pp. 397-404
-
-
Cariou, A.1
Claessens, Y.E.2
Pene, F.3
-
84
-
-
34547797469
-
Vascular injury during elevated glucose can be mitigated by erythropoietin and Wnt signaling
-
Chong, Z. Z., Shang, Y. C. and Maiese, K. (2007) Vascular injury during elevated glucose can be mitigated by erythropoietin and Wnt signaling. Curr. Neurovasc. Res. 4, 194-204
-
(2007)
Curr. Neurovasc. Res
, vol.4
, pp. 194-204
-
-
Chong, Z.Z.1
Shang, Y.C.2
Maiese, K.3
-
85
-
-
34248230733
-
Differential regulation of Foxo3a target genes in erythropoiesis
-
Bakker, W. J., van Dijk, T. B., Parren-van Amelsvoort, M. et al. (2007) Differential regulation of Foxo3a target genes in erythropoiesis. Mol. Cell. Biol. 27, 3839-3854
-
(2007)
Mol. Cell. Biol
, vol.27
, pp. 3839-3854
-
-
Bakker, W.J.1
van Dijk, T.B.2
Parren-van Amelsvoort, M.3
-
86
-
-
0037178789
-
FOXO forkhead transcription factors induce G-M checkpoint in response to oxidative stress
-
Furukawa-Hibi, Y., Yoshida-Araki, K., Ohta, T., Ikeda, K. and Motoyama, N. (2002) FOXO forkhead transcription factors induce G-M checkpoint in response to oxidative stress. J. Biol. Chem. 277, 26729-26732
-
(2002)
J. Biol. Chem
, vol.277
, pp. 26729-26732
-
-
Furukawa-Hibi, Y.1
Yoshida-Araki, K.2
Ohta, T.3
Ikeda, K.4
Motoyama, N.5
-
87
-
-
33846538095
-
Infertility caused by retardation of follicular development in mice with oocyte-specific expression of Foxo3a
-
Liu, L., Rajareddy, S., Reddy, P. et al. (2007) Infertility caused by retardation of follicular development in mice with oocyte-specific expression of Foxo3a. Development 134, 199-209
-
(2007)
Development
, vol.134
, pp. 199-209
-
-
Liu, L.1
Rajareddy, S.2
Reddy, P.3
-
88
-
-
33750152602
-
Mutational screening of FOXO3A and FOXO1A in women with premature ovarian failure
-
Watkins, W. J., Umbers, A. J., Woad, K. J. et al. (2006) Mutational screening of FOXO3A and FOXO1A in women with premature ovarian failure. Fertil. Steril. 86, 1518-1521
-
(2006)
Fertil. Steril
, vol.86
, pp. 1518-1521
-
-
Watkins, W.J.1
Umbers, A.J.2
Woad, K.J.3
-
89
-
-
34547444891
-
Mechanistic insights into diabetes mellitus and oxidative stress
-
Maiese, K., Chong, Z. Z. and Shang, Y. C. (2007) Mechanistic insights into diabetes mellitus and oxidative stress. Curr. Med. Chem. 14, 1729-1738
-
(2007)
Curr. Med. Chem
, vol.14
, pp. 1729-1738
-
-
Maiese, K.1
Chong, Z.Z.2
Shang, Y.C.3
-
90
-
-
33847146814
-
Oxidative stress biology and cell injury during type 1 and type 2 diabetes mellitus
-
Maiese, K., Morhan, S. D. and Chong, Z. Z. (2007) Oxidative stress biology and cell injury during type 1 and type 2 diabetes mellitus. Curr. Neurovasc. Res. 4, 63-71
-
(2007)
Curr. Neurovasc. Res
, vol.4
, pp. 63-71
-
-
Maiese, K.1
Morhan, S.D.2
Chong, Z.Z.3
-
91
-
-
34547906405
-
Diabetes and mortality following acute coronary syndromes
-
Donahoe, S. M., Stewart, G. C., McCabe, C. H. et al. (2007) Diabetes and mortality following acute coronary syndromes. JAMA, J. Am. Med. Assoc. 298, 765-775
-
(2007)
JAMA, J. Am. Med. Assoc
, vol.298
, pp. 765-775
-
-
Donahoe, S.M.1
Stewart, G.C.2
McCabe, C.H.3
-
92
-
-
0033546192
-
Phosphorylation of serine 256 by protein kinase B disrupts transactivation by FKHR and mediates effects of insulin on insulin-like growth factor-binding protein-1 promoter activity through a conserved insulin response sequence
-
Guo, S., Rena, G., Cichy, S., He, X., Cohen, P. and Unterman, T. (1999) Phosphorylation of serine 256 by protein kinase B disrupts transactivation by FKHR and mediates effects of insulin on insulin-like growth factor-binding protein-1 promoter activity through a conserved insulin response sequence. J. Biol. Chem. 274, 17184-17192
-
(1999)
J. Biol. Chem
, vol.274
, pp. 17184-17192
-
-
Guo, S.1
Rena, G.2
Cichy, S.3
He, X.4
Cohen, P.5
Unterman, T.6
-
93
-
-
0033522897
-
Insulin stimulates phosphorylation of the forkhead transcription factor FKHR on serine 253 through a wortmannin-sensitive pathway
-
Nakae, J., Park, B. C. and Accili, D. (1999) Insulin stimulates phosphorylation of the forkhead transcription factor FKHR on serine 253 through a wortmannin-sensitive pathway. J. Biol. Chem. 274, 15982-15985
-
(1999)
J. Biol. Chem
, vol.274
, pp. 15982-15985
-
-
Nakae, J.1
Park, B.C.2
Accili, D.3
-
94
-
-
33748130877
-
Polymorphisms in FOXO gene family and association analysis with BMI
-
Kim, J. R., Jung, H. S., Bae, S. W. et al. (2006) Polymorphisms in FOXO gene family and association analysis with BMI. Obesity 14, 188-193
-
(2006)
Obesity
, vol.14
, pp. 188-193
-
-
Kim, J.R.1
Jung, H.S.2
Bae, S.W.3
-
95
-
-
33847182471
-
Haplotypes in the human Foxo1a and Foxo3a genes; impact on disease and mortality at old age
-
Kuningas, M., Magi, R., Westendorp, R. G., Slagboom, P. E., Remm, M. and van Heemst, D. (2007) Haplotypes in the human Foxo1a and Foxo3a genes; impact on disease and mortality at old age. Eur. J. Hum. Genet. 15, 294-301
-
(2007)
Eur. J. Hum. Genet
, vol.15
, pp. 294-301
-
-
Kuningas, M.1
Magi, R.2
Westendorp, R.G.3
Slagboom, P.E.4
Remm, M.5
van Heemst, D.6
-
96
-
-
33749350412
-
Benfotiamine counteracts glucose toxicity effects on endothelial progenitor cell differentiation via Akt/FoxO signaling
-
Marchetti, V., Menghini, R., Rizza, S. et al. (2006) Benfotiamine counteracts glucose toxicity effects on endothelial progenitor cell differentiation via Akt/FoxO signaling. Diabetes 55, 2231-2237
-
(2006)
Diabetes
, vol.55
, pp. 2231-2237
-
-
Marchetti, V.1
Menghini, R.2
Rizza, S.3
-
97
-
-
7244231007
-
CTLA-4-Ig activates forkhead transcription factors and protects dendritic cells from oxidative stress in nonobese diabetic mice
-
Fallarino, F., Bianchi, R., Orabona, C. et al. (2004) CTLA-4-Ig activates forkhead transcription factors and protects dendritic cells from oxidative stress in nonobese diabetic mice. J. Exp. Med. 200, 1051-1062
-
(2004)
J. Exp. Med
, vol.200
, pp. 1051-1062
-
-
Fallarino, F.1
Bianchi, R.2
Orabona, C.3
-
98
-
-
33845262863
-
1-mediated mesangial cell dysfunction: A novel mechanism related to diabetic kidney disease
-
1-mediated mesangial cell dysfunction: A novel mechanism related to diabetic kidney disease. J. Am. Soc. Nephrol. 17, 3325-3335
-
(2006)
J. Am. Soc. Nephrol
, vol.17
, pp. 3325-3335
-
-
Kato, M.1
Yuan, H.2
Xu, Z.G.3
-
99
-
-
40949164735
-
Forkhead transcription factor FoxO1 in adipose tissue regulates energy storage and expenditure
-
Nakae, J., Cao, Y., Oki, M. et al. (2008) Forkhead transcription factor FoxO1 in adipose tissue regulates energy storage and expenditure. Diabetes 57, 563-576
-
(2008)
Diabetes
, vol.57
, pp. 563-576
-
-
Nakae, J.1
Cao, Y.2
Oki, M.3
-
100
-
-
0037112090
-
Effects of aging and caloric restriction on the gene expression of Foxo1, 3, and 4 (FKHR, FKHRL1, and AFX) in the rat skeletal muscles
-
Furuyama, T., Yamashita, H., Kitayama, K., Higami, Y., Shimokawa, I. and Mori, N. (2002) Effects of aging and caloric restriction on the gene expression of Foxo1, 3, and 4 (FKHR, FKHRL1, and AFX) in the rat skeletal muscles. Microsc. Res. Tech. 59, 331-334
-
(2002)
Microsc. Res. Tech
, vol.59
, pp. 331-334
-
-
Furuyama, T.1
Yamashita, H.2
Kitayama, K.3
Higami, Y.4
Shimokawa, I.5
Mori, N.6
-
101
-
-
38049148308
-
FoxO transcription factors activate Akt and attenuate insulin signaling in heart by inhibiting protein phosphatases
-
Ni, Y. G., Wang, N., Cao, D. J. et al. (2007) FoxO transcription factors activate Akt and attenuate insulin signaling in heart by inhibiting protein phosphatases. Proc. Natl. Acad. Sci. U.S.A. 104, 20517-20522
-
(2007)
Proc. Natl. Acad. Sci. U.S.A
, vol.104
, pp. 20517-20522
-
-
Ni, Y.G.1
Wang, N.2
Cao, D.J.3
-
102
-
-
4544358547
-
Skeletal muscle FOXO1 (FKHR) transgenic mice have less skeletal muscle mass, down-regulated Type I (slow twitch/red muscle) fiber genes, and impaired glycemic control
-
Kamei, Y., Miura, S., Suzuki, M. et al. (2004) Skeletal muscle FOXO1 (FKHR) transgenic mice have less skeletal muscle mass, down-regulated Type I (slow twitch/red muscle) fiber genes, and impaired glycemic control. J. Biol. Chem. 279, 41114-41123
-
(2004)
J. Biol. Chem
, vol.279
, pp. 41114-41123
-
-
Kamei, Y.1
Miura, S.2
Suzuki, M.3
-
104
-
-
10844236451
-
Nutrient availability regulates SIRT1 through a forkhead-dependent pathway
-
Nemoto, S., Fergusson, M. M. and Finkel, T. (2004) Nutrient availability regulates SIRT1 through a forkhead-dependent pathway. Science 306, 2105-2108
-
(2004)
Science
, vol.306
, pp. 2105-2108
-
-
Nemoto, S.1
Fergusson, M.M.2
Finkel, T.3
-
105
-
-
1342264308
-
Mammalian SIRT1 represses forkhead transcription factors
-
Motta, M. C., Divecha, N., Lemieux, M. et al. (2004) Mammalian SIRT1 represses forkhead transcription factors. Cell 116, 551-563
-
(2004)
Cell
, vol.116
, pp. 551-563
-
-
Motta, M.C.1
Divecha, N.2
Lemieux, M.3
-
106
-
-
14644409780
-
Down-regulation of a forkhead transcription factor, FOXO3a, accelerates cellular senescence in human dermal fibroblasts
-
Kyoung Kim, H., Kyoung Kim, Y., Song, I. H. et al. (2005) Down-regulation of a forkhead transcription factor, FOXO3a, accelerates cellular senescence in human dermal fibroblasts. J. Gerontol. A. Biol. Sci. Med. Sci. 60, 4-9
-
(2005)
J. Gerontol. A. Biol. Sci. Med. Sci
, vol.60
, pp. 4-9
-
-
Kyoung Kim, H.1
Kyoung Kim, Y.2
Song, I.H.3
-
107
-
-
34249669270
-
Sirt1 regulates aging and resistance to oxidative stress in the heart
-
Alcendor, R. R., Gao, S., Zhai, P. et al. (2007) Sirt1 regulates aging and resistance to oxidative stress in the heart. Circ. Res. 100, 1512-1521
-
(2007)
Circ. Res
, vol.100
, pp. 1512-1521
-
-
Alcendor, R.R.1
Gao, S.2
Zhai, P.3
-
108
-
-
33845967865
-
Down-regulation of manganese-superoxide dismutase through phosphorylation of FOXO3a by Akt in explanted vascular smooth muscle cells from old rats
-
Li, M., Chiu, J. F., Mossman, B. T. and Fukagawa, N. K. (2006) Down-regulation of manganese-superoxide dismutase through phosphorylation of FOXO3a by Akt in explanted vascular smooth muscle cells from old rats. J. Biol. Chem. 281, 40429-40439
-
(2006)
J. Biol. Chem
, vol.281
, pp. 40429-40439
-
-
Li, M.1
Chiu, J.F.2
Mossman, B.T.3
Fukagawa, N.K.4
-
109
-
-
0842263745
-
Akt negatively regulates the in vitro lifespan of human endothelial cells via a p53/p21-dependent pathway
-
Miyauchi, H., Minamino, T., Tateno, K., Kunieda, T., Toko, H. and Komuro, I. (2004) Akt negatively regulates the in vitro lifespan of human endothelial cells via a p53/p21-dependent pathway. EMBO J. 23, 212-220
-
(2004)
EMBO J
, vol.23
, pp. 212-220
-
-
Miyauchi, H.1
Minamino, T.2
Tateno, K.3
Kunieda, T.4
Toko, H.5
Komuro, I.6
-
110
-
-
0042355359
-
Critical role for Akt1 in the modulation of apoptotic phosphatidylserine exposure and microglial activation
-
Kang, J. Q., Chong, Z. Z. and Maiese, K. (2003) Critical role for Akt1 in the modulation of apoptotic phosphatidylserine exposure and microglial activation. Mol. Pharmacol. 64, 557-569
-
(2003)
Mol. Pharmacol
, vol.64
, pp. 557-569
-
-
Kang, J.Q.1
Chong, Z.Z.2
Maiese, K.3
-
111
-
-
22144441636
-
mGluRI targets microglial activation and selectively prevents neuronal cell engulfment through Akt and caspase dependent pathways
-
Chong, Z. Z., Kang, J., Li, F. and Maiese, K. (2005) mGluRI targets microglial activation and selectively prevents neuronal cell engulfment through Akt and caspase dependent pathways. Curr. Neurovasc. Res. 2, 197-211
-
(2005)
Curr. Neurovasc. Res
, vol.2
, pp. 197-211
-
-
Chong, Z.Z.1
Kang, J.2
Li, F.3
Maiese, K.4
-
112
-
-
33847797307
-
The pro-survival pathways of mTOR and protein kinase B target glycogen synthase kinase-3β and nuclear factor-κB to foster endogenous microglial cell protection
-
Chong, Z. Z., Li, F. and Maiese, K. (2007) The pro-survival pathways of mTOR and protein kinase B target glycogen synthase kinase-3β and nuclear factor-κB to foster endogenous microglial cell protection. Int. J. Mol. Med. 19, 263-272
-
(2007)
Int. J. Mol. Med
, vol.19
, pp. 263-272
-
-
Chong, Z.Z.1
Li, F.2
Maiese, K.3
-
113
-
-
33746910279
-
-
Li, F., Chong, Z. Z. and Maiese, K. (2006) Microglial integrity is maintained by erythropoietin through integration of Akt and its substrates of glycogen synthase kinase-3β, β-catenin, and nuclear factor-κB. Curr. Neurovasc. Res. 3, 187-201
-
Li, F., Chong, Z. Z. and Maiese, K. (2006) Microglial integrity is maintained by erythropoietin through integration of Akt and its substrates of glycogen synthase kinase-3β, β-catenin, and nuclear factor-κB. Curr. Neurovasc. Res. 3, 187-201
-
-
-
-
114
-
-
34547408400
-
Inhibition of forkhead box class O family member transcription factors in rheumatoid synovial tissue
-
Ludikhuize, J., de Launay, D., Groot, D. et al. (2007) Inhibition of forkhead box class O family member transcription factors in rheumatoid synovial tissue. Arthritis Rheum. 56, 2180-2191
-
(2007)
Arthritis Rheum
, vol.56
, pp. 2180-2191
-
-
Ludikhuize, J.1
de Launay, D.2
Groot, D.3
-
115
-
-
36849073263
-
Altered FOXO1 transcript levels in peripheral blood mononuclear cells of systemic lupus erythematosus and rheumatoid arthritis patients
-
Kuo, C. C. and Lin, S. C. (2007) Altered FOXO1 transcript levels in peripheral blood mononuclear cells of systemic lupus erythematosus and rheumatoid arthritis patients. Mol. Med. 13, 561-566
-
(2007)
Mol. Med
, vol.13
, pp. 561-566
-
-
Kuo, C.C.1
Lin, S.C.2
-
116
-
-
4143129696
-
Regulation of NF-κB, Th activation, and autoinflammation by the forkhead transcription factor Foxo3a
-
Lin, L., Hron, J. D. and Peng, S. L. (2004) Regulation of NF-κB, Th activation, and autoinflammation by the forkhead transcription factor Foxo3a. Immunity 21, 203-213
-
(2004)
Immunity
, vol.21
, pp. 203-213
-
-
Lin, L.1
Hron, J.D.2
Peng, S.L.3
-
117
-
-
20944443597
-
Inflammatory arthritis requires Foxo3a to prevent Fas ligand-induced neutrophil apoptosis
-
Jonsson, H., Allen, P. and Peng, S. L. (2005) Inflammatory arthritis requires Foxo3a to prevent Fas ligand-induced neutrophil apoptosis. Nat. Med. 11, 666-671
-
(2005)
Nat. Med
, vol.11
, pp. 666-671
-
-
Jonsson, H.1
Allen, P.2
Peng, S.L.3
-
118
-
-
33751206845
-
The negative regulators Foxj1 and Foxo3a are up-regulated by a peptide that inhibits systemic lupus erythematosus-associated T cell responses
-
Sela, U., Dayan, M., Hershkoviz, R., Cahalon, L., Lider, O. and Mozes, E. (2006) The negative regulators Foxj1 and Foxo3a are up-regulated by a peptide that inhibits systemic lupus erythematosus-associated T cell responses. Eur. J. Immunol. 36, 2971-2980
-
(2006)
Eur. J. Immunol
, vol.36
, pp. 2971-2980
-
-
Sela, U.1
Dayan, M.2
Hershkoviz, R.3
Cahalon, L.4
Lider, O.5
Mozes, E.6
-
119
-
-
33846998653
-
Osteopontin-induced relapse and progression of autoimmune brain disease through enhanced survival of activated T cells
-
Hur, E. M., Youssef, S., Haws, M. E., Zhang, S. Y., Sobel, R. A. and Steinman, L. (2007) Osteopontin-induced relapse and progression of autoimmune brain disease through enhanced survival of activated T cells. Nat. Immunol. 8, 74-83
-
(2007)
Nat. Immunol
, vol.8
, pp. 74-83
-
-
Hur, E.M.1
Youssef, S.2
Haws, M.E.3
Zhang, S.Y.4
Sobel, R.A.5
Steinman, L.6
-
120
-
-
33751165468
-
Adenovirus-mediated gene transfer of FKHRL1 triple mutant efficiently induces apoptosis in melanoma cells
-
Gomez-Gutierrez, J. G., Souza, V., Hao, H. Y. et al. (2006) Adenovirus-mediated gene transfer of FKHRL1 triple mutant efficiently induces apoptosis in melanoma cells. Cancer Biol. Ther. 5, 875-883
-
(2006)
Cancer Biol. Ther
, vol.5
, pp. 875-883
-
-
Gomez-Gutierrez, J.G.1
Souza, V.2
Hao, H.Y.3
-
121
-
-
43549117072
-
Use of multiple biomarkers to improve the prediction of death from cardiovascular causes
-
Zethelius, B., Berglund, L., Sundstrom, J. et al. (2008) Use of multiple biomarkers to improve the prediction of death from cardiovascular causes. N. Engl. J. Med. 358, 2107-2116
-
(2008)
N. Engl. J. Med
, vol.358
, pp. 2107-2116
-
-
Zethelius, B.1
Berglund, L.2
Sundstrom, J.3
|