Identification of a novel family of cell-surface proteins expressed in human vascular endothelium

Journal of Biological Chemistry

Volumn 277, Issue 48, 2002, Pages 46364-46373

  Yang, Ruey Bing ^a   Ng, Chi Kin Domingos ^a   Wasserman, Scott M ^a   Colman, Steven D ^b   Shenoy, Suresh ^b   Mehraban, Fuad ^b   Kömüves, László G ^a   Tomlinson, James E ^a   Topper, James N ^a  

^a MILLENNIUM PHARMACEUTICALS INC   (United States)

^b CURAGEN CORPORATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; DISEASES; DNA; OLIGOMERS; PROTEINS; TUMORS;

INFLAMMATION;

BIOCHEMISTRY;

ANTICOAGULANT PROTEIN; CELL SURFACE PROTEIN; COMPLEMENTARY DNA; EPIDERMAL GROWTH FACTOR; FIBRILLIN; GLYCOPROTEIN; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; MESSENGER RNA; NOTCH RECEPTOR; PROTEIN C; PROTEIN SCUBE1; PROTEIN SCUBE2; THROMBOMODULIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANGIOGENESIS; ARTICLE; BRAIN; CANCER; CARBOXY TERMINAL SEQUENCE; CELL SURFACE; GENE ISOLATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN SITU HYBRIDIZATION; INFLAMMATION; KIDNEY; LIVER; LUNG; METASTASIS; NUCLEOTIDE SEQUENCE; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN SECRETION; SCUBE1 GENE; SCUBE2 GENE; SEQUENCE HOMOLOGY; SPLEEN; VASCULAR DISEASE; VASCULAR ENDOTHELIUM;

AMINO ACID SEQUENCE; BASE SEQUENCE; BLOTTING, NORTHERN; CELL LINE; DNA PRIMERS; DNA, COMPLEMENTARY; ENDOTHELIUM, VASCULAR; GLYCOSYLATION; HUMANS; IN SITU HYBRIDIZATION; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; RNA, MESSENGER;

EID: 0037195861     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M207410200     Document Type: Article

References (57)

1. Topper, J. N., and Gimbrone, M. A., Jr. (1999) Mol. Med. Today 5, 40-46
2. Topper, J. N., Cai, J., Falb, D., and Gimbrone, M. A., Jr. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 10417-10422
3. Rapaport, S. I., and Rao, L. V. (1992) Arterioscler. Thromb. 12, 1111-1121
4. Thompson, E. A., and Salem, H. H. (1986) J. Clin. Invest. 78, 13-17
5. Esmon, C. T. (1995) FASEB J. 9, 946-955
6. Rosen, S. D., and Bertozzi, C. R. (1994) Curr. Opin. Cell Biol. 6, 663-673
7. Johnson, R. C., Zhu, D., Augustin-Voss, H. G., and Pauli, B. U. (1993) J. Cell Biol. 121, 1423-1432
8. Arap, W., Kolonin, M. G., Trepel, M., Lahdenranta, J., Cardo-Vila, M., Giordano, R. J., Mintz, P. J., Ardelt, P. U., Yao, V. J., Vidal, C. I., Chen, L., Flamm, A., Valtanen, H., Weavind, L. M., Hicks, M. E., Pollock, R. E., Botz, G. H., Bucana, C. D., Koivunen, E., Cahill, D., Troncoso, P., Baggerly, K. A., Pentz, R. D., Do, K. A., Logothetis, C. J., and Pasqualini, R. (2002) Nat. Med. 8, 121-127
9. Pasqualini, R., and Ruoslahti, E. (1996) Nature 380, 364-366
10. Rajotte, D., Arap, W., Hagedorn, M., Koivunen, E., Pasqualini, R., and Ruoslahti, E. (1998) J. Clin. Invest. 102, 430-437
11. Yang, R. B., Tomlinson, J. E., Conley, P. B., Hart, M. J., Komuves, L. G., Ziman, M., Lum, P. Y., Roberts, C., and Topper, J. N. (2002) Physiologist 45, 76
12. Hughes, T. R., Mao, M., Jones, A. R., Burchard, J., Marton, M. J., Shannon, K. W., Lefkowitz, S. M., Ziman, M., Schelter, J. M., Meyer, M. R., Kobayashi, S., Davis, C., Dai, H., He, Y. D., Stephaniants, S. B., Cavet, G., Walker, W. L., West, A., Coffey, E., Shoemaker, D. D., Stoughton, R., Blanchard, A. P., Friend, S. H., and Linsley, P. S. (2001) Nat. Biotechnol. 19, 342-347
13. Grimmond, S., Larder, R., Van Hateren, N., Siggers, P., Hulsebos, T. J., Arkell, R., and Greenfield, A. (2000) Genomics 70, 74-81
14. Grimmond, S., Larder, R., Van Hateren, N., Siggers, P., Morse, S., Hacker, T., Arkell, R., and Greenfield, A. (2001) Mech. Dev. 102, 209-211
15. Komuves, L. G., Hanley, K., Lefebvre, A. M., Man, M. Q., Ng, D. C., Bikle, D. D., Williams, M. L., Elias, P. M., Auwerx, J., and Feingold, K. R. (2000) J. Invest. Dermatol. 115, 353-360
16. Komuves, L. G., Feren, A., Jones, A. L., and Fodor, E. (2000) J. Histochem. Cytochem. 48, 821-830
17. Stelnicki, E. J., Komuves, L. G., Kwong, A. O., Holmes, D., Klein, P., Rozenfeld, S., Lawrence, H. J., Adzick, N. S., Harrison, M., and Largman, C. (1998) J. Invest. Dermatol. 110, 110-115
18. Shimkets, R. A., Lowe, D. G., Tai, J. T., Sehl, P., Jin, H., Yang, R., Predki, P. F., Rothberg, B. E., Murtha, M. T., Roth, M. E., Shenoy, S. G., Windemuth, A., Simpson, J. W., Simons, J. F., Daley, M. P., Gold, S. A., McKenna, M. P., Hillan, K., Went, G. T., and Rothberg, J. M. (1999) Nat. Biotechnol. 17, 798-803
19. DiChiara, M. R., Kiely, J. M., Gimbrone, M. A., Lee, M. E., Perrella, M. A., and Topper, J. N. (2000) J. Exp. Med. 192, 695-704
20. Kyte, J., and Doolittle, R. F. (1982) J. Mol. Biol. 157, 105-132
21. Sonnhammer, E. L., Eddy, S. R., and Durbin, R. (1997) Proteins 28, 405-420
22. Prigent, S. A., and Lemoine, N. R. (1992) Prog. Growth Factor Res. 4, 1-24
23. Davis, C. G. (1990) New Biol. 2, 410-419
24. Li, X., Ponten, A., Aase, K., Karlsson, L., Abramsson, A., Uutela, M., Backstrom, G., Hellstrom, M., Bostrom, H., Li, H., Soriano, P., Betsholtz, C., Heldin, C. H., Alitalo, K., Ostman, A., and Eriksson, U. (2000) Nat. Cell Biol. 2, 302-309
25. Gilbertson, D. G., Duff, M. E., West, J. W., Kelly, J. D., Sheppard, P. O., Hofstrand, P. D., Gao, Z., Shoemaker, K., Bukowski, T. R., Moore, M., Feldhaus, A. L., Humes, J. M., Palmer, T. E., and Hart, C. E. (2001) J. Biol. Chem. 276, 27406-27414
26. Bergsten, E., Uutela, M., Li, X., Pietras, K., Ostman, A., Heldin, C. H., Alitalo, K., and Eriksson, U. (2001) Nat. Cell Biol. 3, 512-516
27. LaRochelle, W. J., Jeffers, M., McDonald, W. F., Chillakuru, R. A., Giese, N. A., Lokker, N. A., Sullivan, C., Boldog, F. L., Yang, M., Vernet, C., Burgess, C. E., Fernandes, E., Deegler, L. L., Rittman, B., Shimkets, J., Shimkets, R. A., Rothberg, J. M., and Lichenstein, H. S. (2001) Nat. Cell Biol. 3, 517-521
28. Davies, D. R., and Wlodawer, A. (1995) FASEB J. 9, 50-56
29. Sun, P. D., and Davies, D. R. (1995) Annu. Rev. Biophys. Biomol. Struct. 24, 269-291
30. Yang, R. B., Mark, M. R., Gray, A., Huang, A., Xie, M. H., Zhang, M., Goddard, A., Wood, W. I., Gurney, A. L., and Godowski, P. J. (1998) Nature 395, 284-288
31. Mantovani, A., Bussolino, F., and Dejana, E. (1992) FASEB J. 6, 2591-2599
32. Bork, P., and Beckmann, G. (1993) J. Mol. Biol. 231, 539-545
33. Finelli, A. L., Bossie, C. A., Xie, T., and Padgett, R. W. (1994) Development 120, 861-870
34. Li, S. W., Sieron, A. L., Fertala, A., Hojima, Y., Arnold, W. V., and Prockop, D. J. (1996) Proc. Nat. Acad. Sci. U. S. A. 93, 5127-5130
35. Clark, T. G., Conway, S. J., Scott, I. C., Labosky, P. A., Winnier, G., Bundy, J., Hogan, B. L., and Greenspan, D. S. (1999) Development 126, 2631-2642
36. Delgadillo-Reynoso, M. G., Rollo, D. R., Hursh, D. A., and Raff, R. A. (1989) J. Mol. Evol. 29, 314-327
37. Leytus, S. P., Kurachi, K., Sakariassen, K. S., and Davie, E. W. (1986) Biochemistry 25, 4855-4863
38. Duke-Cohan, J. S., Tang, W., and Schlossman, S. F. (2000) Adv. Exp. Med. Biol. 477, 173-185
39. Duke-Cohan, J. S., Gu, J., McLaughlin, D. F., Xu, Y., Freeman, G. J., and Schlossman, S. F. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 11336-11341
40. Rebay, I., Fleming, R. J., Fehon, R. G., Cherbas, L., Cherbas, P., and Artavanis-Tsakonas, S. (1991) Cell 67, 687-699
41. Dietz, H. C, Cutting, G. R., Pyeritz, R. E, Maslen, C. L., Sakai, L. Y., Corson, G. M., Puffenberger, E. G., Hamosh, A., Nanthakumar, E. J., Curristin, S. M., Stetten, G., Meyers, D. A., and Francomano, C. A. (1991) Nature 352, 337-339
42. Taipale, J., and Keski-Oja, J. (1997) FASEB J. 11, 51-59
43. Saharinen, J., Taipale, J., Monni, O., and Keski-Oja, J. (1998) J. Biol. Chem. 273, 18459-18469
44. Munger, J. S., Harpel, J. G., Gleizes, P. E., Mazzieri, R., Nunes, I., and Rifkin, D. B. (1997) Kidney Int. 51, 1376-1382
45. Gleizes, P. E., Munger, J. S., Nunes, I., Harpel, J. G., Mazzieri, R., Noguera, I., and Rifkin, D. B. (1997) Stem Cells 15, 190-197
46. Starnes, T., Robertson, M. J., Sledge, G., Kelich, S., Nakshatri, H., Broxmeyer, H. E., and Hromas, R. (2001) J. Immunol. 167, 4137-4140
47. Smith, C. W. (1993) Semin. Hematol. 30, 45-53
48. Handford, P. A., Mayhew, M., Baron, M., Winship, P. R., Campbell, I. D., and Brownlee, G. G. (1991) Nature 351, 164-167
49. Rao, Z., Handford, P., R, Mayhew, M., Knott, V., Brownlee, G. G., and Stuart, D. (1995) Cell 82, 131-141
50. Persson, E., and Nielsen, L. S. (1998) Blood Coagul. Fibrinolysis 9, S79-S81
51. Zushi, M., Gomi, K., Honda, G., Kondo, S., Yamamoto, S., Hayashi, T., and Suzuki, K. (1991) J. Biol. Chem. 266, 19886-19889
52. Yu, S., Zhang, L., Jhingan, A., Christiansen, W. T., and Castellino, F. J. (1994) Biochemistry 33, 823-831
53. Boehme, M. W., Deng, Y., Raeth, U., Bierhaus, A., Ziegler, R., Stremmel, W., and Nawroth, P. P. (1996) Immunology 87, 134-140
54. Nawroth, P. P., and Stern, D. M. (1986) J. Exp. Med. 163, 740-745
55. Kapiotis, S., Besemer, J., Bevec, D., Valent, P., Bettelheim, P., Lechner, K., and Speiser, W. (1991) Blood 78, 410-415
56. Moore, K. L, Andreoli, S. P., Esmon, N. L., Esmon, C. T., and Bang, N. U. (1987) J. Clin. Invest. 79, 124-130
57. Moore, K. L., Esmon, C. T., and Esmon, N. L. (1989) Blood 73, 159-165