메뉴 건너뛰기




Volumn 75, Issue 8-10, 2012, Pages 478-491

Impact of eugenol and isoeugenol on AhR translocation, target gene expression, and proliferation in human HaCaT keratinocytes

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIC HYDROCARBON RECEPTOR; CELL CYCLE PROTEIN; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE 6; CYCLIN DEPENDENT KINASE INHIBITOR 1B; CYTOCHROME P450 1A1; EUGENOL; ISOEUGENOL; RETINOBLASTOMA PROTEIN;

EID: 84862564299     PISSN: 15287394     EISSN: 10872620     Source Type: Journal    
DOI: 10.1080/15287394.2012.674916     Document Type: Article
Times cited : (20)

References (50)
  • 1
    • 33947319795 scopus 로고    scopus 로고
    • 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) exposure of normal human dermal fibroblasts results in AhR-dependent and -independent changes in gene expression
    • Akintobi, A. M., Villano, C. M., and White, L. A. 2007. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) exposure of normal human dermal fibroblasts results in AhR-dependent and -independent changes in gene expression. Toxicol. Appl. Pharmacol. 220: 9-17.
    • (2007) Toxicol. Appl. Pharmacol. , vol.220 , pp. 9-17
    • Akintobi, A.M.1    Villano, C.M.2    White, L.A.3
  • 3
    • 77953763391 scopus 로고    scopus 로고
    • Characterization of N-acetyltransferase 1 activity in human keratinocytes and modulation by paraphenylenediamine
    • Bonifas, J., Scheitza, S., Clemens, J., and Blomeke, B. 2010. Characterization of N-acetyltransferase 1 activity in human keratinocytes and modulation by paraphenylenediamine. J. Pharmacol. Exp. Ther. 334: 318-26.
    • (2010) J. Pharmacol. Exp. Ther. , vol.334 , pp. 318-326
    • Bonifas, J.1    Scheitza, S.2    Clemens, J.3    Blomeke, B.4
  • 4
    • 0032861582 scopus 로고    scopus 로고
    • Resveratrol has antagonist activity on the aryl hydrocarbon receptor: Implications for prevention of dioxin toxicity
    • Casper, R. F., Quesne, M., Rogers, I. M., Shirota, T., Jolivet, A., Milgrom, E., and Savouret, J. F. 1999. Resveratrol has antagonist activity on the aryl hydrocarbon receptor: Implications for prevention of dioxin toxicity. Mol. Pharmacol. 56: 784-90.
    • (1999) Mol. Pharmacol. , vol.56 , pp. 784-790
    • Casper, R.F.1    Quesne, M.2    Rogers, I.M.3    Shirota, T.4    Jolivet, A.5    Milgrom, E.6    Savouret, J.F.7
  • 5
    • 0036176605 scopus 로고    scopus 로고
    • Inducing the cell cycle arrest and apoptosis of oral KB carcinoma cells by hydroxychavicol: Roles of glutathione and reactive oxygen species
    • Chang, M. C., Uang, B. J., Wu, H. L., Lee, J. J., Hahn, L. J., and Jeng, J. H. 2002. Inducing the cell cycle arrest and apoptosis of oral KB carcinoma cells by hydroxychavicol: roles of glutathione and reactive oxygen species. Br. J. Pharmacol. 135: 619-30.
    • (2002) Br. J. Pharmacol. , vol.135 , pp. 619-630
    • Chang, M.C.1    Uang, B.J.2    Wu, H.L.3    Lee, J.J.4    Hahn, L.J.5    Jeng, J.H.6
  • 6
    • 0032406634 scopus 로고    scopus 로고
    • The Ah receptor: A regulator of the biochemical and toxicological actions of structurally diverse chemicals
    • Denison, M. S., and Heath-Pagliuso, S. 1998. The Ah receptor: a regulator of the biochemical and toxicological actions of structurally diverse chemicals. Bull. Environ. Contam. Toxicol. 61: 557-68.
    • (1998) Bull. Environ. Contam. Toxicol. , vol.61 , pp. 557-568
    • Denison, M.S.1    Heath-Pagliuso, S.2
  • 7
    • 0038768712 scopus 로고    scopus 로고
    • Activation of the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous chemicals
    • Denison, M. S., and Nagy, S. R. 2003. Activation of the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous chemicals. Annu. Rev. Pharmacol. Toxicol. 43: 309-34.
    • (2003) Annu. Rev. Pharmacol. Toxicol. , vol.43 , pp. 309-334
    • Denison, M.S.1    Nagy, S.R.2
  • 8
    • 0035985190 scopus 로고    scopus 로고
    • Recruitment of dioxin receptor to active transcription sites
    • Elbi, C., Misteli, T., and Hager, G. L. 2002. Recruitment of dioxin receptor to active transcription sites. Mol. Biol. Cell 13: 2001-15.
    • (2002) Mol. Biol. Cell , vol.13 , pp. 2001-2015
    • Elbi, C.1    Misteli, T.2    Hager, G.L.3
  • 9
    • 0642286536 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor-mediated cell cycle control
    • Elferink, C. J. 2003. Aryl hydrocarbon receptor-mediated cell cycle control. Prog. Cell Cycle Res. 5: 261-67.
    • (2003) Prog. Cell Cycle Res. , vol.5 , pp. 261-267
    • Elferink, C.J.1
  • 10
    • 0035065262 scopus 로고    scopus 로고
    • Maximal aryl hydrocarbon receptor activity depends on an interaction with the retinoblastoma protein
    • Elferink, C. J., Ge, N. L., and Levine A. 2001. Maximal aryl hydrocarbon receptor activity depends on an interaction with the retinoblastoma protein. Mol. Pharmacol. 59: 664-73.
    • (2001) Mol. Pharmacol. , vol.59 , pp. 664-673
    • Elferink, C.J.1    Ge, N.L.2    Levine, A.3
  • 11
    • 0032575589 scopus 로고    scopus 로고
    • A direct interaction between the aryl hydrocarbon receptor and retinoblastoma protein. Linking dioxin signaling to the cell cycle
    • Ge, N. L., and Elferink, C. J. 1998. A direct interaction between the aryl hydrocarbon receptor and retinoblastoma protein. Linking dioxin signaling to the cell cycle. J. Biol. Chem. 273: 22708-13.
    • (1998) J. Biol. Chem. , vol.273 , pp. 22708-22713
    • Ge, N.L.1    Elferink, C.J.2
  • 12
    • 14044263057 scopus 로고    scopus 로고
    • Eugenol causes melanoma growth suppression through inhibition of E2F1 transcriptional activity
    • Ghosh, R., Nadiminty, N., Fitzpatrick, J. E., Alworth, W. L., Slaga, T. J., and Kumar, A. P. 2005. Eugenol causes melanoma growth suppression through inhibition of E2F1 transcriptional activity. J. Biol. Chem. 280: 5812-19.
    • (2005) J. Biol. Chem. , vol.280 , pp. 5812-5819
    • Ghosh, R.1    Nadiminty, N.2    Fitzpatrick, J.E.3    Alworth, W.L.4    Slaga, T.J.5    Kumar, A.P.6
  • 13
    • 33846893672 scopus 로고    scopus 로고
    • Eugenol inhibit 7,12-dimethylbenz[a]anthracene-induced genotoxicity in MCF-7 cells: Bifunctional effects on CYP1 and NAD(P)H:quinone oxidoreductase
    • Han, E. H., Hwang, Y. P., Jeong, T. C., Lee, S. S., Shin, J. G., and Jeong, H. G. 2007. Eugenol inhibit 7,12-dimethylbenz[a]anthracene-induced genotoxicity in MCF-7 cells: Bifunctional effects on CYP1 and NAD(P)H:quinone oxidoreductase. FEBS Lett. 581: 749-56.
    • (2007) FEBS Lett. , vol.581 , pp. 749-756
    • Han, E.H.1    Hwang, Y.P.2    Jeong, T.C.3    Lee, S.S.4    Shin, J.G.5    Jeong, H.G.6
  • 14
    • 0028987872 scopus 로고
    • The aryl hydrocarbon receptor complex
    • Hankinson, O. 1995. The aryl hydrocarbon receptor complex. Annu. Rev. Pharmacol. Toxicol. 35: 307-40.
    • (1995) Annu. Rev. Pharmacol. Toxicol. , vol.35 , pp. 307-340
    • Hankinson, O.1
  • 15
    • 80053459335 scopus 로고    scopus 로고
    • Cross talk between keratinocytes and dendritic cells: Impact on the prediction of sensitization
    • Hennen, J., Aeby, P, Goebel, C., Schettgen, T., Oberli, O., Kalmes, M., and Blömeke, B. 2011. Cross talk between keratinocytes and dendritic cells: Impact on the prediction of sensitization. Toxicol. Sci. 123: 501-10.
    • (2011) Toxicol. Sci. , vol.123 , pp. 501-510
    • Hennen, J.1    Aeby, P.2    Goebel, C.3    Schettgen, T.4    Oberli, O.5    Kalmes, M.6    Blömeke, B.7
  • 16
    • 11244353490 scopus 로고    scopus 로고
    • Multiple mechanisms are involved in Ah receptor-mediated cell cycle arrest
    • Huang, G., and Elferink, C. J. 2005. Multiple mechanisms are involved in Ah receptor-mediated cell cycle arrest. Mol. Pharmacol. 67: 88-96.
    • (2005) Mol. Pharmacol. , vol.67 , pp. 88-96
    • Huang, G.1    Elferink, C.J.2
  • 17
    • 1842418966 scopus 로고    scopus 로고
    • Cell density regulates intracellular localization of aryl hydrocarbon receptor
    • Ikuta, T., Kobayashi, Y., and Kawajiri, K. 2004. Cell density regulates intracellular localization of aryl hydrocarbon receptor. J. Biol. Chem. 279: 19209-16.
    • (2004) J. Biol. Chem. , vol.279 , pp. 19209-19216
    • Ikuta, T.1    Kobayashi, Y.2    Kawajiri, K.3
  • 19
    • 33748744452 scopus 로고    scopus 로고
    • Impact of the arylhydrocarbon receptor on eugenol- And isoeugenol-induced cell cycle arrest in human immortalized keratinocytes (HaCaT)
    • Kalmes, M., Neumeyer, A., Rio, P., Hanenberg, H., Fritsche, E., and Blömeke, B. 2006. Impact of the arylhydrocarbon receptor on eugenol- and isoeugenol-induced cell cycle arrest in human immortalized keratinocytes (HaCaT). Biol. Chem. 387: 1201-7.
    • (2006) Biol. Chem. , vol.387 , pp. 1201-1207
    • Kalmes, M.1    Neumeyer, A.2    Rio, P.3    Hanenberg, H.4    Fritsche, E.5    Blömeke, B.6
  • 20
    • 77949907273 scopus 로고    scopus 로고
    • Eugenol precludes cutaneous chemicalcarcinogenesis in mouse by preventing oxidative stress and inflammation and by inducing apoptosis
    • Kaur, G., Athar, M., and Alam, M. S. 2010. Eugenol precludes cutaneous chemicalcarcinogenesis in mouse by preventing oxidative stress and inflammation and by inducing apoptosis. Mol. Carcinogen. 49: 290-301.
    • (2010) Mol. Carcinogen. , vol.49 , pp. 290-301
    • Kaur, G.1    Athar, M.2    Alam, M.S.3
  • 22
    • 0033166447 scopus 로고    scopus 로고
    • p27(Kip1) induction and inhibition of proliferation by the intracellular Ah receptor in developing thymus and hepatoma cells
    • Kolluri, S. K.,Weiss, C., Koff, A., and Göttlicher, M. 1999. p27(Kip1) induction and inhibition of proliferation by the intracellular Ah receptor in developing thymus and hepatoma cells. Genes Dev 13: 1742-53.
    • (1999) Genes Dev , vol.13 , pp. 1742-1753
    • Kolluri, S.K.1    Weiss, C.2    Koff, A.3    Göttlicher, M.4
  • 23
    • 33748889106 scopus 로고    scopus 로고
    • Towards the development of a pragmatic technique for isolating and differentiating nestin-positive cells from human scalp skin into neuronal and glial cell populations: Generating neurons from human skin?
    • Kruse, C., Bodo, E., Petschnik, A. E., Danner, S., Tiede, S., and Paus, R. 2006. Towards the development of a pragmatic technique for isolating and differentiating nestin-positive cells from human scalp skin into neuronal and glial cell populations: Generating neurons from human skin? Exp. Dermatol. 15: 794-800.
    • (2006) Exp. Dermatol. , vol.15 , pp. 794-800
    • Kruse, C.1    Bodo, E.2    Petschnik, A.E.3    Danner, S.4    Tiede, S.5    Paus, R.6
  • 25
    • 0034969560 scopus 로고    scopus 로고
    • Induction of CYP1A1. The AhR/DRE paradigm: Transcription, receptor regulation, and expanding biological roles
    • Ma, Q. 2001. Induction of CYP1A1. The AhR/DRE paradigm: Transcription, receptor regulation, and expanding biological roles. Curr. Drug Metab. 2: 149-64.
    • (2001) Curr. Drug Metab. , vol.2 , pp. 149-164
    • Ma, Q.1
  • 26
    • 0032077398 scopus 로고    scopus 로고
    • Characterisation of xenobiotic-metabolising enzyme expression in human bronchial mucosa and peripheral lung tissues
    • Mace, K., Bowman, E. D., Vautravers, P., Shields, P. G., Harris, C. C., and Pfeifer, A. M. 1998. Characterisation of xenobiotic-metabolising enzyme expression in human bronchial mucosa and peripheral lung tissues. Eur. J. Cancer 34: 914-20.
    • (1998) Eur. J. Cancer , vol.34 , pp. 914-920
    • Mace, K.1    Bowman, E.D.2    Vautravers, P.3    Shields, P.G.4    Harris, C.C.5    Pfeifer, A.M.6
  • 27
    • 79151472984 scopus 로고    scopus 로고
    • Eugenol inhibits cell proliferation via NF-kappaB suppression in a rat model of gastric carcinogenesis induced by MNNG
    • Manikandan, P., Vinothini, G., Vidya Priyadarsini, R., Prathiba, D., and Nagini, S. 2011. Eugenol inhibits cell proliferation via NF-kappaB suppression in a rat model of gastric carcinogenesis induced by MNNG. Invest. New Drugs 29: 110-17.
    • (2011) Invest. New Drugs , vol.29 , pp. 110-117
    • Manikandan, P.1    Vinothini, G.2    Vidya Priyadarsini, R.3    Prathiba, D.4    Nagini, S.5
  • 28
    • 54249157595 scopus 로고    scopus 로고
    • The aryl hydrocarbon receptor binds to E2F1 and inhibits E2F1-induced apoptosis
    • Marlowe, J. L., Fan, Y., Chang, X., Peng, L., Knudsen, E. S., Xia, Y., and Puga A. 2008. The aryl hydrocarbon receptor binds to E2F1 and inhibits E2F1-induced apoptosis. Mol. Biol. Cell 19: 3263-71.
    • (2008) Mol. Biol. Cell , vol.19 , pp. 3263-3271
    • Marlowe, J.L.1    Fan, Y.2    Chang, X.3    Peng, L.4    Knudsen, E.S.5    Xia, Y.6    Puga, A.7
  • 29
    • 3142747089 scopus 로고    scopus 로고
    • The aryl hydrocarbon receptor displaces p300 from E2F-dependent promoters and represses S phasespecific gene expression
    • Marlowe, J. L., Knudsen, E. S., Schwemberger, S., and Puga, A. 2004. The aryl hydrocarbon receptor displaces p300 from E2F-dependent promoters and represses S phasespecific gene expression. J. Biol. Chem. 279: 29013-22.
    • (2004) J. Biol. Chem. , vol.279 , pp. 29013-29022
    • Marlowe, J.L.1    Knudsen, E.S.2    Schwemberger, S.3    Puga, A.4
  • 30
    • 38649111292 scopus 로고    scopus 로고
    • Red clover isoflavones biochanin A and formononetin are potent ligands of the human aryl hydrocarbon receptor
    • Medjakovic, S., and Jungbauer, A. 2008. Red clover isoflavones biochanin A and formononetin are potent ligands of the human aryl hydrocarbon receptor. J. Steroid Biochem. Mol. Biol. 108: 171-77.
    • (2008) J. Steroid Biochem. Mol. Biol. , vol.108 , pp. 171-177
    • Medjakovic, S.1    Jungbauer, A.2
  • 31
    • 60649095638 scopus 로고    scopus 로고
    • Timing is everything: Consequences of transient and sustained AhR activity
    • Mitchell, K. A., and Elferink, C. J. 2008. Timing is everything: Consequences of transient and sustained AhR activity. Biochem. Pharmacol. 77: 947-56.
    • (2008) Biochem. Pharmacol. , vol.77 , pp. 947-956
    • Mitchell, K.A.1    Elferink, C.J.2
  • 32
    • 38949097735 scopus 로고    scopus 로고
    • The search for endogenous activators of the aryl hydrocarbon receptor
    • Nguyen, L. P., and Bradfield, C. A. 2008. The search for endogenous activators of the aryl hydrocarbon receptor. Chem. Res. Toxicol. 21: 102-16.
    • (2008) Chem. Res. Toxicol. , vol.21 , pp. 102-116
    • Nguyen, L.P.1    Bradfield, C.A.2
  • 33
    • 23344447557 scopus 로고    scopus 로고
    • Induction of cytotoxicity and apoptosis and inhibition of cyclooxygenase-2 gene expression by eugenol-related compounds
    • Okada, N., Hirata, A., Murakami, Y., Shoji, M., Sakagami, H., and Fujisawa, S. 2005. Induction of cytotoxicity and apoptosis and inhibition of cyclooxygenase-2 gene expression by eugenol-related compounds. Anticancer Res. 25: 3263-69.
    • (2005) Anticancer Res. , vol.25 , pp. 3263-3269
    • Okada, N.1    Hirata, A.2    Murakami, Y.3    Shoji, M.4    Sakagami, H.5    Fujisawa, S.6
  • 34
    • 17644407682 scopus 로고    scopus 로고
    • Phospho-ser 15-p53 translocates into mitochondria and interacts with Bcl-2 and Bcl-xL in eugenol-induced apoptosis
    • Park, B. S., Song, Y. S., Yee, S. B., Lee, B. G., Seo, S. Y., Park, Y. C., Kim, J. M., Kim, H. M., and Yoo, Y. H. 2005. Phospho-ser 15-p53 translocates into mitochondria and interacts with Bcl-2 and Bcl-xL in eugenol-induced apoptosis. Apoptosis 10: 193-200.
    • (2005) Apoptosis , vol.10 , pp. 193-200
    • Park, B.S.1    Song, Y.S.2    Yee, S.B.3    Lee, B.G.4    Seo, S.Y.5    Park, Y.C.6    Kim, J.M.7    Kim, H.M.8    Yoo, Y.H.9
  • 36
    • 0034723264 scopus 로고    scopus 로고
    • Aromatic hydrocarbon receptor interaction with the retinoblastoma protein potentiates repression of E2F-dependent transcriptionand cell cycle arrest
    • Puga, A., Barnes, S. J., Dalton, T. P., Chang, C., Knudsen, E. S., and Maier M. A. 2000. Aromatic hydrocarbon receptor interaction with the retinoblastoma protein potentiates repression of E2F-dependent transcriptionand cell cycle arrest. J. Biol. Chem. 275: 2943-50.
    • (2000) J. Biol. Chem. , vol.275 , pp. 2943-2950
    • Puga, A.1    Barnes, S.J.2    Dalton, T.P.3    Chang, C.4    Knudsen, E.S.5    Maier, M.A.6
  • 37
    • 0037145022 scopus 로고    scopus 로고
    • Role of the aryl hydrocarbon receptor in cell cycle regulation
    • Puga, A., Xia, Y., and Elferink, C. 2002. Role of the aryl hydrocarbon receptor in cell cycle regulation. Chem. Biol. Interact. 141: 117-30.
    • (2002) Chem. Biol. Interact. , vol.141 , pp. 117-130
    • Puga, A.1    Xia, Y.2    Elferink, C.3
  • 38
    • 0141682540 scopus 로고    scopus 로고
    • Alteration of keratinocyte differentiation and senescence by the tumor promoter dioxin
    • Ray, S. S., and Swanson, H. I. 2003. Alteration of keratinocyte differentiation and senescence by the tumor promoter dioxin. Toxicol. Appl. Pharmacol. 192: 131-45.
    • (2003) Toxicol. Appl. Pharmacol. , vol.192 , pp. 131-145
    • Ray, S.S.1    Swanson, H.I.2
  • 39
    • 3042695024 scopus 로고    scopus 로고
    • Dioxin-induced immortalization of normal human keratinocytes and silencing of p53 and p16INK4a
    • Ray, S. S., and Swanson, H. I. 2004. Dioxin-induced immortalization of normal human keratinocytes and silencing of p53 and p16INK4a. J. Biol. Chem. 279: 27187-93.
    • (2004) J. Biol. Chem. , vol.279 , pp. 27187-27193
    • Ray, S.S.1    Swanson, H.I.2
  • 40
    • 0036791156 scopus 로고    scopus 로고
    • Curcumin activates the aryl hydrocarbon receptor yet significantly inhibits (-)-benzo(a)pyrene-7Rtrans-7,8-dihydrodiol bioactivation in oral squamous cell carcinoma cells and oral mucosa
    • Rinaldi, A. L., Morse, M. A., Fields, H. W., Rothas, D. A., Pei, P., Rodrigo, K. A., Renner, R. J., and Mallery, S. R. 2002. Curcumin activates the aryl hydrocarbon receptor yet significantly inhibits (-)-benzo(a)pyrene-7Rtrans- 7,8-dihydrodiol bioactivation in oral squamous cell carcinoma cells and oral mucosa. Cancer Res. 62: 5451-56.
    • (2002) Cancer Res. , vol.62 , pp. 5451-5456
    • Rinaldi, A.L.1    Morse, M.A.2    Fields, H.W.3    Rothas, D.A.4    Pei, P.5    Rodrigo, K.A.6    Renner, R.J.7    Mallery, S.R.8
  • 41
    • 0034769011 scopus 로고    scopus 로고
    • Regulation of Cyp1a1 induction by dioxin as a function of cell cycle phase
    • Santini, R. P., Myrand, S., Elferink, C., and Reiners, J. J., Jr. 2001. Regulation of Cyp1a1 induction by dioxin as a function of cell cycle phase. J. Pharmacol. Exp. Ther. 299: 718-28.
    • (2001) J. Pharmacol. Exp. Ther. , vol.299 , pp. 718-728
    • Santini, R.P.1    Myrand, S.2    Elferink, C.3    Reiners Jr., J.J.4
  • 43
    • 0034611601 scopus 로고    scopus 로고
    • Restoration of retinoblastoma mediated signaling to Cdk2 results in cell cycle arrest
    • Strobeck, M. W., Fribourg, A. F. Puga, A. and Knudsen, E. S. 2000. Restoration of retinoblastoma mediated signaling to Cdk2 results in cell cycle arrest. Oncogene 19: 1857-67.
    • (2000) Oncogene , vol.19 , pp. 1857-1867
    • Strobeck, M.W.1    Fribourg, A.F.2    Puga, A.3    Knudsen, E.S.4
  • 44
    • 0037463319 scopus 로고    scopus 로고
    • DNA damage and cell cycle arrest induced by 2-(4-amino-3-methylphenyl)-5- fluorobenzothiazole (5F 203, NSC 703786) is attenuated in aryl hydrocarbon receptor deficient MCF-7 cells
    • Trapani, V., Patel, V., Leong, C. O., Ciolino, H. P., Yeh, G. C., Hose, C., Trepel, J. B., Stevens, M. F., Sausville, E. A., and Loaiza-Perez, A. I. 2003. DNA damage and cell cycle arrest induced by 2-(4-amino-3-methylphenyl)-5- fluorobenzothiazole (5F 203, NSC 703786) is attenuated in aryl hydrocarbon receptor deficient MCF-7 cells. Br. J. Cancer 88: 599-605.
    • (2003) Br. J. Cancer , vol.88 , pp. 599-605
    • Trapani, V.1    Patel, V.2    Leong, C.O.3    Ciolino, H.P.4    Yeh, G.C.5    Hose, C.6    Trepel, J.B.7    Stevens, M.F.8    Sausville, E.A.9    Loaiza-Perez, A.I.10
  • 46
    • 0034819385 scopus 로고    scopus 로고
    • Langerhans cells and immature dendritic cells as model systems for screening of skin sensitizers
    • Tuschl, H., and Kovac J. A. 2001. Langerhans cells and immature dendritic cells as model systems for screening of skin sensitizers. Toxicol. In Vitro 15: 327-31.
    • (2001) Toxicol. In Vitro , vol.15 , pp. 327-331
    • Tuschl, H.1    Kovac, J.A.2
  • 47
    • 17144373652 scopus 로고    scopus 로고
    • Assessment of potency of allergenic activity of low molecular weight compounds based on IL-1 alpha and IL-18 production by a murine and human keratinocyte cell line
    • Van Och, F. M., Van Loveren, H., Van Wolfswinkel, J. C., Machielsen, A. J., and Vandebriel, R. J. 2005. Assessment of potency of allergenic activity of low molecular weight compounds based on IL-1 alpha and IL-18 production by a murine and human keratinocyte cell line. Toxicology 210: 95-109.
    • (2005) Toxicology , vol.210 , pp. 95-109
    • Van Och, F.M.1    Van Loveren, H.2    Van Wolfswinkel, J.C.3    Machielsen, A.J.4    Vandebriel, R.J.5
  • 48
    • 0028012079 scopus 로고
    • Dioxin-responsive genes: Examination of dose-response relationships using quantitative reverse transcriptase-polymerase chain reaction
    • Vanden Heuvel, J. P., Clark, G. C., Kohn, M. C., Tritscher, A. M., Greenlee, W. F., Lucier, G. W., and Bell D. A. 1994. Dioxin-responsive genes: Examination of dose-response relationships using quantitative reverse transcriptase-polymerase chain reaction. Cancer Res. 54: 62-68.
    • (1994) Cancer Res. , vol.54 , pp. 62-68
    • Vanden Heuvel, J.P.1    Clark, G.C.2    Kohn, M.C.3    Tritscher, A.M.4    Greenlee, W.F.5    Lucier, G.W.6    Bell, D.A.7
  • 49
    • 0032849820 scopus 로고    scopus 로고
    • Fragrance and contact allergens in vitro modulate the HLA-DR and E- Cadherin expression on human epidermal Langerhans cells
    • Verrier, A. C., Schmitt, D., and Staquet, M. J. 1999. Fragrance and contact allergens in vitro modulate the HLA-DR and E- cadherin expression on human epidermal Langerhans cells. Int. Arch. Allergy Immunol. 120: 56-62.
    • (1999) Int. Arch. Allergy Immunol. , vol.120 , pp. 56-62
    • Verrier, A.C.1    Schmitt, D.2    Staquet, M.J.3
  • 50
    • 0347481466 scopus 로고    scopus 로고
    • Characteristic expression of aryl hydrocarbon receptor repressor gene in human tissues: Organ-specific distribution and variable induction patterns in mononuclear cells
    • Yamamoto, J., Ihara, K., Nakayama, H., Hikino, S., Satoh, K., Kubo, N., Iida, T., Fujii, Y., and Hara T. 2004. Characteristic expression of aryl hydrocarbon receptor repressor gene in human tissues: Organ-specific distribution and variable induction patterns in mononuclear cells. Life Sci. 74: 1039-49.
    • (2004) Life Sci. , vol.74 , pp. 1039-1049
    • Yamamoto, J.1    Ihara, K.2    Nakayama, H.3    Hikino, S.4    Satoh, K.5    Kubo, N.6    Iida, T.7    Fujii, Y.8    Hara, T.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.