Eugenol inhibits cell proliferation via NF-κB suppression in a rat model of gastric carcinogenesis induced by MNNG

Investigational New Drugs

Volumn 29, Issue 1, 2011, Pages 110-117

  Manikandan, P ^a   Vinothini, G ^a   Vidya Priyadarsini, R ^a   Prathiba, D ^b   Nagini, S ^a  

^a ANNAMALAI UNIVERSITY   (India)

^b SRI RAMACHANDRA UNIVERSITY   (India)

Author keywords

Cell proliferation; Chemoprevention; Eugenol; Gastric carcinogenesis; MNNG

Indexed keywords

CYCLIN B; CYCLIN D1; CYCLINE; EUGENOL; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 45; I KAPPA B ALPHA; I KAPPA B KINASE BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; METHYLNITRONITROSOGUANIDINE; PROTEIN P21; PROTEIN P50; PROTEIN P53; SYNAPTOTAGMIN I;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CHEMOTHERAPY; CANCER INHIBITION; CANCER PREVENTION; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; HISTOPATHOLOGY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; RAT; SIGNAL TRANSDUCTION; STOMACH CARCINOGENESIS; STOMACH CARCINOMA; STOMACH PROTECTION; UPREGULATION; WESTERN BLOTTING;

ANIMALS; BODY WEIGHT; CELL PROLIFERATION; DISEASE MODELS, ANIMAL; DRUG SCREENING ASSAYS, ANTITUMOR; EUGENOL; GENE EXPRESSION REGULATION, NEOPLASTIC; IMMUNOHISTOCHEMISTRY; MALE; METHYLNITRONITROSOGUANIDINE; NF-KAPPA B; RATS; RATS, WISTAR; RNA, MESSENGER; SIGNAL TRANSDUCTION; STOMACH; STOMACH NEOPLASMS;

EID: 79151472984     PISSN: 01676997     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10637-009-9345-2     Document Type: Article

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