Eugenol but not isoeugenol induces CYPIA1 mRNA in human keratinocytes

International Archives of Allergy and Immunology

Volumn 124, Issue 1-3, 2001, Pages 309-311

  Al Masaoudi, Tlaytmas ^a   Sieben, Sonja ^a   Callahan, Christina P ^a   Merk, Hans F ^a   Blömeke, Brunhilde ^a  

^a UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

Author keywords

CYPIA1, mRNA induction; Eugenol; Fragrances; Keratinocytes; Metabolism

Indexed keywords

CYTOCHROME P450 1A1; EUGENOL; FRAGRANCE; ISOEUGENOL;

ARTICLE; CELL CULTURE; CONCENTRATION RESPONSE; CONTACT DERMATITIS; CONTROLLED STUDY; CULTURE MEDIUM; ENZYME INDUCTION; HUMAN; HUMAN CELL; KERATINOCYTE; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 0035051568     PISSN: 10182438     EISSN: None     Source Type: Journal    
DOI: 10.1159/000053742     Document Type: Article

References (9)

1. The frequency of fragrance allergy in a patch-test population over a 17-year period
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4. Cytochrome P450 1B1: A major P450 isoenzyme in human blood monocytes and macrophage subsets
5. Characterization of xenobiotic-metabolizing enzyme expression in human bronchial mucosa and peripheral lung tissues
6. Multiple cytochrome P450-isoenzymes mRNA are expressed in dendritic cells
7. Possible origin of the skin sensitization potential of isoeugenol and related compounds. 1 Preliminary studies of potential mechanisms
8. Evaluation of the sensitizing potential of eugenol and isoeugenol in mice and guinea pigs
9. Skin sensitization to eugenol and isoeugenol in mice: Possible metabolic pathways involving ortho-quinone and quinone methide intermediates