-
1
-
-
0037764668
-
Aryl hydrocarbon receptor gene silencing with small inhibitory RNA differentially modulates Ah-responsiveness in MCF-7 and HepG2 cancer cells
-
Abdelrahim, M., Smith, R. 3rd, and Safe, S. (2003). Aryl hydrocarbon receptor gene silencing with small inhibitory RNA differentially modulates Ah-responsiveness in MCF-7 and HepG2 cancer cells. Mol. Pharmacol. 63, 1373-1381.
-
(2003)
Mol. Pharmacol.
, vol.63
, pp. 1373-1381
-
-
Abdelrahim, M.1
Smith III, R.2
Safe, S.3
-
2
-
-
0029052683
-
Inhibitory effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on rat hepatocyte proliferation induced by 2/3 partial hepatectomy
-
Bauman, J.W., Goldsworthy, T.L., Dunn, C.S., and Fox, T.R. (1995). Inhibitory effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on rat hepatocyte proliferation induced by 2/3 partial hepatectomy. Cell Prolif. 28, 437-451.
-
(1995)
Cell Prolif.
, vol.28
, pp. 437-451
-
-
Bauman, J.W.1
Goldsworthy, T.L.2
Dunn, C.S.3
Fox, T.R.4
-
3
-
-
0030897705
-
Ligand-dependent interaction of the aryl hydrocarbon receptor with a novel immunophilin homolog in vivo
-
Carver, L.A. and Bradfield, C.A. (1997). Ligand-dependent interaction of the aryl hydrocarbon receptor with a novel immunophilin homolog in vivo. J. Biol. Chem. 272, 11452-11456.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 11452-11456
-
-
Carver, L.A.1
Bradfield, C.A.2
-
4
-
-
0642286536
-
Aryl hydrocarbon receptor-mediated cell cycle control
-
Elferink, C.J. (2003). Aryl hydrocarbon receptor-mediated cell cycle control. Prog. Cell Cycle Res. 5, 261-267.
-
(2003)
Prog. Cell Cycle Res.
, vol.5
, pp. 261-267
-
-
Elferink, C.J.1
-
5
-
-
0035065262
-
Maximal aryl hydrocarbon receptor activity depends on an interaction with the retinoblastoma protein
-
Elferink, C.J., Ge, N.L., and Levine, A. (2001). Maximal aryl hydrocarbon receptor activity depends on an interaction with the retinoblastoma protein. Mol. Pharmacol. 59, 664-673.
-
(2001)
Mol. Pharmacol.
, vol.59
, pp. 664-673
-
-
Elferink, C.J.1
Ge, N.L.2
Levine, A.3
-
6
-
-
0034099303
-
2/M phases in aryl hydrocarbon receptor-null embryo fibroblasts
-
2/M phases in aryl hydrocarbon receptor-null embryo fibroblasts. Mol. Pharmacol. 57, 1056-1063.
-
(2000)
Mol. Pharmacol.
, vol.57
, pp. 1056-1063
-
-
Elizondo, G.1
Fernandez-Salguero, P.2
Sheikh, M.S.3
Kim, G.Y.4
Fornace, A.J.5
Lee, K.S.6
Gonzalez, F.J.7
-
7
-
-
0030582844
-
Analysis of structural requirements for Ah receptor antagonist activity: Ellipticines, flavones, and related compounds
-
Gasiewicz, T.A., Kende, A.S., Rucci, G., Whitney, B., and Willey, J.J. (1996). Analysis of structural requirements for Ah receptor antagonist activity: ellipticines, flavones, and related compounds. Biochem. Pharmacol. 52, 1787-1803.
-
(1996)
Biochem. Pharmacol.
, vol.52
, pp. 1787-1803
-
-
Gasiewicz, T.A.1
Kende, A.S.2
Rucci, G.3
Whitney, B.4
Willey, J.J.5
-
8
-
-
0032575589
-
A direct interaction between the aryl hydrocarbon receptor and retinoblastoma protein. Linking dioxin signaling to the cell cycle
-
Ge, N.L. and Elferink, C.J. (1998). A direct interaction between the aryl hydrocarbon receptor and retinoblastoma protein. Linking dioxin signaling to the cell cycle. J. Biol. Chem. 273, 22708-22713.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 22708-22713
-
-
Ge, N.L.1
Elferink, C.J.2
-
9
-
-
14044263057
-
Eugenol causes melanoma growth suppression through inhibition of E2F1 transcriptional activity
-
Ghosh, R., Nadiminty, N., Fitzpatrick, J.E., Alworth, W.L., Slaga, T.J., and Kumar, A.P. (2005). Eugenol causes melanoma growth suppression through inhibition of E2F1 transcriptional activity. J. Biol. Chem. 280, 5812-5819.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 5812-5819
-
-
Ghosh, R.1
Nadiminty, N.2
Fitzpatrick, J.E.3
Alworth, W.L.4
Slaga, T.J.5
Kumar, A.P.6
-
10
-
-
0021266601
-
Reversible inhibition of in vitro epithelial cell proliferation by 2,3,7,8-tetrachlorodibenzo-p-dioxin
-
Gierthy, J.F. and Crane, D. (1984). Reversible inhibition of in vitro epithelial cell proliferation by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicol. Appl. Pharmacol. 74, 91-98.
-
(1984)
Toxicol. Appl. Pharmacol.
, vol.74
, pp. 91-98
-
-
Gierthy, J.F.1
Crane, D.2
-
11
-
-
0032447116
-
The aryl hydrocarbon receptor: Studies using the AHR-null mice
-
Gonzalez, F.J. and Fernandez-Salguero, P. (1998). The aryl hydrocarbon receptor: studies using the AHR-null mice. Drug Metab. Dispos. 26, 1194-1198.
-
(1998)
Drug Metab. Dispos.
, vol.26
, pp. 1194-1198
-
-
Gonzalez, F.J.1
Fernandez-Salguero, P.2
-
12
-
-
0028987872
-
The aryl hydrocarbon receptor complex
-
Hankinson, O. (1995). The aryl hydrocarbon receptor complex. Annu. Rev. Pharmacol. Toxicol. 35, 307-340.
-
(1995)
Annu. Rev. Pharmacol. Toxicol.
, vol.35
, pp. 307-340
-
-
Hankinson, O.1
-
13
-
-
11244353490
-
Multiple mechanisms are involved in Ah receptor-mediated cell cycle arrest
-
Huang, G. and Elferink, C.J. (2005). Multiple mechanisms are involved in Ah receptor-mediated cell cycle arrest. Mol. Pharmacol. 67, 88-96.
-
(2005)
Mol. Pharmacol.
, vol.67
, pp. 88-96
-
-
Huang, G.1
Elferink, C.J.2
-
14
-
-
0029611136
-
2,3,7,8-Tetrachlorodibenzo-p-dioxin inhibits DNA synthesis in rat primary hepatocytes
-
Hushka, D.R. and Greenlee, W.F. (1995). 2,3,7,8-Tetrachlorodibenzo-p- dioxin inhibits DNA synthesis in rat primary hepatocytes. Mutat. Res. 333, 89-99.
-
(1995)
Mutat. Res.
, vol.333
, pp. 89-99
-
-
Hushka, D.R.1
Greenlee, W.F.2
-
15
-
-
1842418966
-
Cell density regulates intracellular localization of aryl hydrocarbon receptor
-
Ikuta, T., Kobayashi, Y., and Kawajiri, K. (2004). Cell density regulates intracellular localization of aryl hydrocarbon receptor. J. Biol. Chem. 279, 19209-19216.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 19209-19216
-
-
Ikuta, T.1
Kobayashi, Y.2
Kawajiri, K.3
-
16
-
-
2942616516
-
A constitutively active arylhydrocarbon receptor induces growth inhibition of jurkat T cells through changes in the expression of genes related to apoptosis and cell cycle arrest
-
Ito, T., Tsukumo, S., Suzuki, N., Motohashi, H., Yamamoto, M., Fujii-Kuriyama, Y., Mimura, J., Lin, T.M., Peterson, R.E., Tohyama, C., and Nohara, K. (2004). A constitutively active arylhydrocarbon receptor induces growth inhibition of jurkat T cells through changes in the expression of genes related to apoptosis and cell cycle arrest. J. Biol. Chem. 279, 25204-25210.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 25204-25210
-
-
Ito, T.1
Tsukumo, S.2
Suzuki, N.3
Motohashi, H.4
Yamamoto, M.5
Fujii-Kuriyama, Y.6
Mimura, J.7
Lin, T.M.8
Peterson, R.E.9
Tohyama, C.10
Nohara, K.11
-
17
-
-
2442531799
-
2,3,7,8-Tetrachlorodibenzo-p-dioxin inhibits cell proliferation through arylhydrocarbon receptor-mediated G1 arrest in SK-N-SH human neuronal cells
-
Jin, D.Q., Jung, J.W., Lee, Y.S., and Kim, J.A. (2004). 2,3,7,8-Tetrachlorodibenzo-p-dioxin inhibits cell proliferation through arylhydrocarbon receptor-mediated G1 arrest in SK-N-SH human neuronal cells. Neurosci. Lett. 363, 69-72.
-
(2004)
Neurosci. Lett.
, vol.363
, pp. 69-72
-
-
Jin, D.Q.1
Jung, J.W.2
Lee, Y.S.3
Kim, J.A.4
-
18
-
-
0033531928
-
Evidence that the co-chaperone p23 regulates ligand responsiveness of the dioxin (aryl hydrocarbon) receptor
-
Kazlauskas, A., Poellinger, L., and Pongratz, I. (1999). Evidence that the co-chaperone p23 regulates ligand responsiveness of the dioxin (aryl hydrocarbon) receptor. J. Biol. Chem. 274, 13519-13524.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 13519-13524
-
-
Kazlauskas, A.1
Poellinger, L.2
Pongratz, I.3
-
19
-
-
0033166447
-
p27(Kip1) induction and inhibition of proliferation by the intracellular Ah receptor in developing thymus and hepatoma cells
-
Kolluri, S.K., Weiss, C., Koff, A., and Gottlicher, M. (1999). p27(Kip1) induction and inhibition of proliferation by the intracellular Ah receptor in developing thymus and hepatoma cells. Genes Dev. 13, 1742-1753.
-
(1999)
Genes Dev.
, vol.13
, pp. 1742-1753
-
-
Kolluri, S.K.1
Weiss, C.2
Koff, A.3
Gottlicher, M.4
-
20
-
-
0344089002
-
+ cord blood cells
-
+ cord blood cells. Hum. Gene Ther. 14, 509-519.
-
(2003)
Hum. Gene Ther.
, vol.14
, pp. 509-519
-
-
Leurs, C.1
Jansen, M.2
Pollok, K.E.3
Heinkelein, M.4
Schmidt, M.5
Wissler, M.6
Lindemann, D.7
Von Kalle, C.8
Rethwilm, A.9
Williams, D.A.10
Hanenberg, H.11
-
21
-
-
24344483878
-
Smad4 dependency defines two classes of transforming growth factor β (TGF-β) target genes and distinguishes TGF-β-induced epithelial-mesenchymal transition from its antiproliferative and migratory responses
-
Levy, L. and Hill, C.S. (2005). Smad4 dependency defines two classes of transforming growth factor β (TGF-β) target genes and distinguishes TGF-β-induced epithelial-mesenchymal transition from its antiproliferative and migratory responses. Mol. Cell. Biol. 25, 8108-8125.
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 8108-8125
-
-
Levy, L.1
Hill, C.S.2
-
22
-
-
0028815347
-
Identification of 3′-methoxy-4′-nitroflavone as a pure aryl hydrocarbon (Ah) receptor antagonist and evidence for more than one form of the nuclear Ah receptor in MCF-7 human breast cancer cells
-
Lu, Y.F., Santostefano, M., Cunningham, B.D., Threadgill, M.D., and Safe, S. (1995). Identification of 3′-methoxy-4′-nitroflavone as a pure aryl hydrocarbon (Ah) receptor antagonist and evidence for more than one form of the nuclear Ah receptor in MCF-7 human breast cancer cells. Arch. Biochem. Biophys. 316, 470-477.
-
(1995)
Arch. Biochem. Biophys.
, vol.316
, pp. 470-477
-
-
Lu, Y.F.1
Santostefano, M.2
Cunningham, B.D.3
Threadgill, M.D.4
Safe, S.5
-
23
-
-
0034969560
-
Induction of CYP1A1. The AhR/DRE paradigm: Transcription, receptor regulation, and expanding biological roles
-
Ma, Q. (2001). Induction of CYP1A1. The AhR/DRE paradigm: transcription, receptor regulation, and expanding biological roles. Curr. Drug Metab. 2, 149-164.
-
(2001)
Curr. Drug Metab.
, vol.2
, pp. 149-164
-
-
Ma, Q.1
-
24
-
-
0029963257
-
The aromatic hydrocarbon receptor modulates the Hepa 1c1c7 cell cycle and differentiated state independently of dioxin
-
Ma, Q. and Whitlock Jr., J.P. (1996). The aromatic hydrocarbon receptor modulates the Hepa 1c1c7 cell cycle and differentiated state independently of dioxin. Mol. Cell Biol. 16, 2144-2150.
-
(1996)
Mol. Cell Biol.
, vol.16
, pp. 2144-2150
-
-
Ma, Q.1
Whitlock Jr., J.P.2
-
25
-
-
0031002895
-
A novel cytoplasmic protein that interacts with the Ah receptor, contains tetratricopeptide repeat motifs, and augments the transcriptional response to 2,3,7,8-tetrachlorodibenzo-p-dioxin
-
Ma, Q. and Whitlock Jr., J.P. (1997). A novel cytoplasmic protein that interacts with the Ah receptor, contains tetratricopeptide repeat motifs, and augments the transcriptional response to 2,3,7,8-tetrachlorodibenzo-p-dioxin. J. Biol. Chem. 272, 8878-8884.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 8878-8884
-
-
Ma, Q.1
Whitlock Jr., J.P.2
-
26
-
-
0032077398
-
Characterization of xenobiotic-metabolizing enzyme expression in human bronchial mucosa and peripheral lung tissues
-
Mace, K., Bowman, E., Vautravers, P., Shields, P., Harris, C., and Pfeifer, A. (1998). Characterization of xenobiotic-metabolizing enzyme expression in human bronchial mucosa and peripheral lung tissues. Eur. J. Cancer 34, 914-920.
-
(1998)
Eur. J. Cancer
, vol.34
, pp. 914-920
-
-
Mace, K.1
Bowman, E.2
Vautravers, P.3
Shields, P.4
Harris, C.5
Pfeifer, A.6
-
27
-
-
3142747089
-
The aryl hydrocarbon receptor displaces p300 from E2F-dependent promoters and represses S phase-specific gene expression
-
Marlowe, J.L., Knudsen, E.S., Schwemberger, S., and Puga, A. (2004). The aryl hydrocarbon receptor displaces p300 from E2F-dependent promoters and represses S phase-specific gene expression. J. Biol. Chem. 279, 29013-29022.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 29013-29022
-
-
Marlowe, J.L.1
Knudsen, E.S.2
Schwemberger, S.3
Puga, A.4
-
28
-
-
0031882767
-
Hepatitis B virus X-associated protein 2 is a subunit of the unliganded aryl hydrocarbon receptor core complex and exhibits transcriptional enhancer activity
-
Meyer, B.K., Pray-Grant, M.G., Vanden Heuvel, J.P., and Perdew, G.H. (1998). Hepatitis B virus X-associated protein 2 is a subunit of the unliganded aryl hydrocarbon receptor core complex and exhibits transcriptional enhancer activity. Mol. Cell. Biol. 18, 978-988.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 978-988
-
-
Meyer, B.K.1
Pray-Grant, M.G.2
Vanden Heuvel, J.P.3
Perdew, G.H.4
-
29
-
-
0023742858
-
Association of the Ah receptor with the 90-kDa heat shock protein
-
Perdew, G.H. (1988). Association of the Ah receptor with the 90-kDa heat shock protein. J. Biol. Chem. 263, 13802-13805.
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 13802-13805
-
-
Perdew, G.H.1
-
30
-
-
0034723264
-
Aromatic hydrocarbon receptor interaction with the retinoblastoma protein potentiates repression of E2F-dependent transcription and cell cycle arrest
-
Puga, A., Barnes, S.J., Dalton, T.P., Chang, C., Knudsen, E.S., and Maier, M.A. (2000). Aromatic hydrocarbon receptor interaction with the retinoblastoma protein potentiates repression of E2F-dependent transcription and cell cycle arrest. J. Biol. Chem. 275, 2943-2950.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 2943-2950
-
-
Puga, A.1
Barnes, S.J.2
Dalton, T.P.3
Chang, C.4
Knudsen, E.S.5
Maier, M.A.6
-
31
-
-
0037184810
-
Role of the aryl hydrocarbon receptor in cell cycle regulation
-
Puga, A., Marlowe, J., Barnes, S., Chang, C.Y., Maier, A., Tan, Z., Kerzee, J.K., Chang, X., Strobeck, M., and Knudsen, E.S. (2002a). Role of the aryl hydrocarbon receptor in cell cycle regulation. Toxicology 181-182, 171-177.
-
(2002)
Toxicology
, vol.181-182
, pp. 171-177
-
-
Puga, A.1
Marlowe, J.2
Barnes, S.3
Chang, C.Y.4
Maier, A.5
Tan, Z.6
Kerzee, J.K.7
Chang, X.8
Strobeck, M.9
Knudsen, E.S.10
-
32
-
-
0037145022
-
Role of the aryl hydrocarbon receptor in cell cycle regulation
-
Puga, A., Xia, Y., and Elferink, C. (2002b). Role of the aryl hydrocarbon receptor in cell cycle regulation. Chem. Biol. Interact. 141, 117-130.
-
(2002)
Chem. Biol. Interact.
, vol.141
, pp. 117-130
-
-
Puga, A.1
Xia, Y.2
Elferink, C.3
-
33
-
-
3042695024
-
Dioxin-induced immortalization of normal human keratinocytes and silencing of p53 and p16INK4a
-
Ray, S.S. and Swanson, H.I. (2004). Dioxin-induced immortalization of normal human keratinocytes and silencing of p53 and p16INK4a. J. Biol. Chem. 279, 27187-27193.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 27187-27193
-
-
Ray, S.S.1
Swanson, H.I.2
-
35
-
-
0035341191
-
Characterization of T cell responses to fragrances
-
Sieben, S., Hertl, M., Al Masaoudi, T., Merk, H.F., and Blomeke, B. (2001). Characterization of T cell responses to fragrances. Toxicol. Appl. Pharmacol. 172, 172-178.
-
(2001)
Toxicol. Appl. Pharmacol.
, vol.172
, pp. 172-178
-
-
Sieben, S.1
Hertl, M.2
Al Masaoudi, T.3
Merk, H.F.4
Blomeke, B.5
-
36
-
-
6344254478
-
Cytochrome P450 expression in human keratinocytes: An aryl hydrocarbon receptor perspective
-
Swanson, H.I. (2004). Cytochrome P450 expression in human keratinocytes: an aryl hydrocarbon receptor perspective. Chem. Biol. Interact. 149, 69-79.
-
(2004)
Chem. Biol. Interact.
, vol.149
, pp. 69-79
-
-
Swanson, H.I.1
-
37
-
-
27144441070
-
Constitutive expression of aryl hydrocarbon receptor in keratinocytes causes inflammatory skin lesions
-
Tauchi, M., Hida, A., Negishi, T., Katsuoka, F., Noda, S., Mimura, J., Hosoya, T., Yanaka, A., Aburatani, H., Fujii-Kuriyama, Y., et al. (2005). Constitutive expression of aryl hydrocarbon receptor in keratinocytes causes inflammatory skin lesions. Mol. Cell. Biol. 25, 9360-9368.
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 9360-9368
-
-
Tauchi, M.1
Hida, A.2
Negishi, T.3
Katsuoka, F.4
Noda, S.5
Mimura, J.6
Hosoya, T.7
Yanaka, A.8
Aburatani, H.9
Fujii-Kuriyama, Y.10
-
38
-
-
0028012079
-
Dioxin-responsive genes: Examination of dose-response relationships using quantitative reverse transcriptase-polymerase chain reaction
-
Vanden Heuvel, J.P., Clark, G.C., Kohn, M.C., Tritscher, A.M., Greenlee, W.F., Lucier, G.W., and Bell, D.A. (1994). Dioxin-responsive genes: examination of dose-response relationships using quantitative reverse transcriptase- polymerase chain reaction. Cancer Res. 54, 62-68.
-
(1994)
Cancer Res.
, vol.54
, pp. 62-68
-
-
Vanden Heuvel, J.P.1
Clark, G.C.2
Kohn, M.C.3
Tritscher, A.M.4
Greenlee, W.F.5
Lucier, G.W.6
Bell, D.A.7
-
39
-
-
0031034058
-
A benzo[a]pyrene-induced cell cycle checkpoint resulting in p53-independent G1 arrest in 3T3 fibroblasts
-
Vaziri, C. and Faller, D.V. (1997). A benzo[a]pyrene-induced cell cycle checkpoint resulting in p53-independent G1 arrest in 3T3 fibroblasts. J. Biol. Chem. 272, 2762-2769.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 2762-2769
-
-
Vaziri, C.1
Faller, D.V.2
-
40
-
-
0032529403
-
Aryl hydrocarbon receptor-mediated antiestrogenicity in MCF-7 cells: Modulation of hormone-induced cell cycle enzymes
-
Wang, W., Smith, R. 3rd, and Safe, S. (1998). Aryl hydrocarbon receptor-mediated antiestrogenicity in MCF-7 cells: modulation of hormone-induced cell cycle enzymes. Arch. Biochem. Biophys. 356, 239-248.
-
(1998)
Arch. Biochem. Biophys.
, vol.356
, pp. 239-248
-
-
Wang, W.1
Smith III, R.2
Safe, S.3
-
41
-
-
0001459262
-
Complementation of Ah receptor deficiency in hepatoma cells: Negative feedback regulation and cell cycle control by the Ah receptor
-
Weiss, C., Kolluri, S.K., Kiefer, F., and Gottlicher, M. (1996). Complementation of Ah receptor deficiency in hepatoma cells: negative feedback regulation and cell cycle control by the Ah receptor. Exp. Cell Res. 226, 154-163.
-
(1996)
Exp. Cell Res.
, vol.226
, pp. 154-163
-
-
Weiss, C.1
Kolluri, S.K.2
Kiefer, F.3
Gottlicher, M.4
-
42
-
-
0043210428
-
Conditional suppression of cellsular genes: Lentivirus vector-mediated drug-inducible RNA interference
-
Wiznerowicz, M. and Trono, D. (2003). Conditional suppression of cellsular genes: lentivirus vector-mediated drug-inducible RNA interference. J. Virol. 77, 8957-8961.
-
(2003)
J. Virol.
, vol.77
, pp. 8957-8961
-
-
Wiznerowicz, M.1
Trono, D.2
|