In vitro cytotoxicity of cyclodextrin-bonded birch bark extract

Planta Medica

Volumn 78, Issue 9, 2012, Pages 881-889

  Hertrampf, Anke ^a   Gründemann, Carsten ^a   Jäger, Sebastian ^b,d   Laszczyk, Melanie ^b,d   Giesemann, Torsten ^c   Huber, Roman ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

^b Birken AG   (Germany)

^c CHARLES RIVER LABORATORIES   (United States)

^d Betulin Institute   (Germany)

Author keywords

anthroposophical medicine; Betula alba; Betulaceae; betulin; cyclodextrin; hepatocytes; triterpenoids

Indexed keywords

APOPTOSIS INDUCING FACTOR; BETULIC ACID; BETULIN; BIRCH BARK EXTRACT; CASPASE 3; CASPASE 7; CYCLODEXTRIN; ERYTHRODIOL; LUPEOL; MASLINIC ACID; PLANT EXTRACT; PROPIDIUM IODIDE; PROTEIN P53; TRITERPENOID; TRITON X 100; TYLOXAPOL; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BARK; BIRCH; CANCER CELL; CANCER CELL CULTURE; CELL ASSAY; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG SELECTIVITY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; HUMAN TISSUE; IC 50; IMMUNOBLOTTING; IN VITRO STUDY; LIVER CANCER; MONOLAYER CULTURE; NONHUMAN; PRIMARY TUMOR; TUMOR XENOGRAFT;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; APOPTOSIS INDUCING FACTOR; BETULA; CASPASE 3; CASPASE 7; CELL LINE, TUMOR; CELL PROLIFERATION; CYCLODEXTRINS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; FEMALE; HEPATOCYTES; HUMANS; INHIBITORY CONCENTRATION 50; LIVER NEOPLASMS; MALE; MICE; PLANT BARK; PLANT EXTRACTS; TUMOR SUPPRESSOR PROTEIN P53; XENOGRAFT MODEL ANTITUMOR ASSAYS;

ANIMALIA; BETULA PUBESCENS; BETULACEAE;

EID: 84862538244     PISSN: 00320943     EISSN: 14390221     Source Type: Journal    
DOI: 10.1055/s-0031-1298473     Document Type: Article

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