Improvement of water solubility and in vitro dissolution rate of gliclazide by complexation with β-cyclodextrin

Pharmaceutica Acta Helvetiae

Volumn 74, Issue 4, 2000, Pages 365-370

  Özkan, Yalçn ^a   Atay, Tamer ^a   Dikmen, Necati ^a   Işimer, Aşkn ^a   Aboul Enein, Hassan Y ^b  

^a GULHANE SCHOOL OF MEDICINE   (Turkey)

^b KING FAISAL SPECIALIST HOSPITAL AND RESEARCH CENTER   (Saudi Arabia)

Author keywords

Cyclodextrin; Dissolution rate; Gliclazide; Neutralization; Recrysstalization; Solubility

Indexed keywords

BETA CYCLODEXTRIN; GLICLAZIDE;

ARTICLE; COMPLEX FORMATION; CRYSTALLIZATION; DISSOLUTION; DRUG SOLUBILITY; INFRARED SPECTROSCOPY; X RAY DIFFRACTION;

BETA-CYCLODEXTRINS; CYCLODEXTRINS; EXCIPIENTS; GLICLAZIDE; HYPOGLYCEMIC AGENTS; KINETICS; SOLUBILITY; SPECTROPHOTOMETRY, INFRARED; X-RAY DIFFRACTION;

EID: 0033996850     PISSN: 00316865     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0031-6865(99)00063-1     Document Type: Article

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