Improvement in solubility and dissolution rate of flavonoids by complexation with β-cyclodextrin

Journal of Pharmaceutical and Biomedical Analysis

Volumn 35, Issue 2, 2004, Pages 379-387

  Tommasini, Silvana ^a   Raneri, Daniela ^a   Ficarra, Rita ^a   Calabrò, Maria Luisa ^a   Stancanelli, Rosanna ^a   Ficarra, Paola ^a  

^a UNIVERSITY OF MESSINA   (Italy)

Author keywords

Cyclodextrin; Dissolution; Hesperetin; Naringenin; Phase solubility studies

Indexed keywords

BETA CYCLODEXTRIN; FLAVONOID; HESPERETIN; NARINGENIN;

AQUEOUS SOLUTION; COMPLEX FORMATION; CONFERENCE PAPER; DISSOLUTION; DRUG SOLUBILITY; DRUG STABILITY; PH; PRIORITY JOURNAL; TEMPERATURE DEPENDENCE; THERMODYNAMICS;

BETA-CYCLODEXTRINS; FLAVONOIDS; SOLUBILITY; SOLUTIONS;

EID: 1942504011     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0731-7085(03)00647-2     Document Type: Conference Paper

References (21)

1. J.B. Harborne, The Flavonoids - Advances in Research since 1986, first ed., Chapman and Hall, London, 1994.
2. P. Pietta, in: C.A. Rice-Evans, L. Packer (Eds.), Flavonoids in Health and Disease, Marcel Dekker Inc., New York, 1998, pp. 61-110.
3. R. Salvayre, A. Nègre, A. Affany, M. Lenoble, L. Douste-Blazy, in: V. Cody, E. Middleton, J.B. Harborne, A. Beretz (Eds.), Plant Flavonoids in Biology and Medicine II. Biochemical, Cellular and Medicinal Properties, A.R. Liss, Inc., New York, 1988, pp. 313-316.
4. Rice-Evans C.A., Miller N.J., Paganga G. Free Radic. Biol. Med. 20:1996;933-956.
5. Cao G., Sofic E., Prior R.L. Free Radic. Biol. Med. 22:1997;749-760.
6. Yutzing C., Rongliang Z., Zhonghan J., Yong J. Free Radic. Biol. Med. 9:1990;19-21.
7. P.C.H. Hollman, M.B. Katan, in: C.A. Rice-Evans, L. Packer (Eds.), Flavonoids in Health and Disease, Marcel Dekker Inc., New York, 1998, pp. 483-522.
8. Loftsson T., Brewster M.E. J. Pharm. Sci. 85:1996;1017-1025.
9. Miyake K., Hirayama F., Uekama K. J. Pharm. Sci. 88:1999;39-45.
10. Frijlink H.W., Schoonen A.J.M., Lerk C.F. Int. J. Pharm. 49:1989;91-102.
11. Zarzycki P.K., Lamparczyk H. J. Pharm. Biomed. Anal. 18:1998;165-170.
12. Loukas Y.L., Vraka V., Gregoridias G. J. Pharm. Biomed. Anal. 16:1997;263-268.
13. Bernar Bernad M.J., Gracia-Mora J., Diaz D., Mendoza Diaz G. J. Incl. Phenom. Macro. Chem. 34:1999;1-18.
14. Hoshino T., Uekama K., Pitha J. Int. J. Pharm. 98:1993;239-242.
15. Higuchi T., Connors K.A. Adv. Anal. Chem. Instr. 4:1965;117-212.
16. H.M. Abdou, in: Dissolution Bioavailability & Bioequivalence, Mack Publishing Company, Easton, Pennsylvania, 1989.
17. Ficarra R., Tommasini S., Raneri D., Calabrò M.L., Di Bella M.R., Rustichelli C., Gamberini M.C., Ficarra P. J. Pharm. Biomed. Anal. 29:2002;1005-1014.
18. T.S. Wiedman, Remington's Pharmaceutical Sciences, 18th ed., Mack Publishing Company, Pennsylvania, 1990, pp. 197-206.
19. Farmacopea Ufficiale della Repubblica Italiana X edizione, Istituto Poligrafico e Zecca dello Stato, Roma, 1998.
20. Jovanovic S.V., Steenken S., Tosic M., Marjanovic B., Simic M.G. J. Am. Chem. Soc. 116:1994;4846-4852.
21. Li P., Tabibi S.E., Yalkowsky S.H. J. Pharm. Sci. 87:1998;1535-1537.