메뉴 건너뛰기




Volumn 7, Issue 12, 1996, Pages 1643-1650

Expression of p53 in Saos-2 osteosarcoma cells induces apoptosis which can be inhibited by Bcl-2 or the adenovirus E1B-55 kDa protein

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN BCL 2; PROTEIN P53; VIRUS PROTEIN;

EID: 0029847416     PISSN: 10449523     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (56)

References (63)
  • 2
    • 0018760324 scopus 로고
    • Characterization of a 54K dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells
    • Linzer, D. I., and Levine, A. J. Characterization of a 54K dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells. Cell, 17: 43-52, 1979.
    • (1979) Cell , vol.17 , pp. 43-52
    • Linzer, D.I.1    Levine, A.J.2
  • 3
    • 0020079972 scopus 로고
    • Adenovirus E1b 58Kd tumor antigen and SV40 large tumor antigen are physically associated with the same 54Kd cellular protein in transformed cells
    • Sarnow, P., Ho, Y. S., Williams, J., and Levine, A. J. Adenovirus E1b 58Kd tumor antigen and SV40 large tumor antigen are physically associated with the same 54Kd cellular protein in transformed cells. Cell, 28: 387-394, 1982.
    • (1982) Cell , vol.28 , pp. 387-394
    • Sarnow, P.1    Ho, Y.S.2    Williams, J.3    Levine, A.J.4
  • 4
    • 0025242481 scopus 로고
    • Dissection of functional domains in the adenovirus 2 early 1B 55K polypeptide by suppressor-linker insertional mutagenesis
    • Yew, P. R., Kao, C. C., and Berk, A. J. Dissection of functional domains in the adenovirus 2 early 1B 55K polypeptide by suppressor-linker insertional mutagenesis. Virology, 179: 795-805, 1990.
    • (1990) Virology , vol.179 , pp. 795-805
    • Yew, P.R.1    Kao, C.C.2    Berk, A.J.3
  • 5
    • 0027358723 scopus 로고
    • The HPV-16 E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53
    • Scheffner, M., Huibregtse, J. M., Vierstra, R. D., and Howley, P. M. The HPV-16 E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53. Cell, 75: 495-505, 1993.
    • (1993) Cell , vol.75 , pp. 495-505
    • Scheffner, M.1    Huibregtse, J.M.2    Vierstra, R.D.3    Howley, P.M.4
  • 6
    • 0027458942 scopus 로고
    • The p53-tumor suppressor gene as a common cellular target in human carcinogenesis
    • Chang, F., Syrjanen, S., Kurvinen, K., and Syrjanen, K. The p53-tumor suppressor gene as a common cellular target in human carcinogenesis. Am. J. Gastroenterol., 88: 174-186, 1993.
    • (1993) Am. J. Gastroenterol. , vol.88 , pp. 174-186
    • Chang, F.1    Syrjanen, S.2    Kurvinen, K.3    Syrjanen, K.4
  • 8
    • 0024382760 scopus 로고
    • The p53 proto-oncogene can act as a suppressor of transformation
    • Finlay, C. A., Hinds, P. W., and Levine, A. J. The p53 proto-oncogene can act as a suppressor of transformation. Cell, 57: 1083-1093, 1989.
    • (1989) Cell , vol.57 , pp. 1083-1093
    • Finlay, C.A.1    Hinds, P.W.2    Levine, A.J.3
  • 10
    • 0025964061 scopus 로고
    • Induction of growth arrest by a temperature-sensitive p53 mutant is correlated with increased nuclear localization and decreased stability of the protein
    • Ginsberg, D., Michael, M. D., Ginsberg, D., and Oren, M. Induction of growth arrest by a temperature-sensitive p53 mutant is correlated with increased nuclear localization and decreased stability of the protein. Mol. Cell. Biol., 11: 582-585, 1991.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 582-585
    • Ginsberg, D.1    Michael, M.D.2    Ginsberg, D.3    Oren, M.4
  • 12
    • 0025784539 scopus 로고
    • Wild-type p53 induces apoptosis of myeloid leukaemia cells that is inhibited by interleukin-6
    • Yonish-Rouach, E., Resnitzky, D., Lotem, J., Sachs, L., Kimchi, A., and Oren, M. Wild-type p53 induces apoptosis of myeloid leukaemia cells that is inhibited by interleukin-6. Nature (Lond.), 352: 345-347, 1991.
    • (1991) Nature (Lond.) , vol.352 , pp. 345-347
    • Yonish-Rouach, E.1    Resnitzky, D.2    Lotem, J.3    Sachs, L.4    Kimchi, A.5    Oren, M.6
  • 13
    • 0025887476 scopus 로고
    • Wild-type p53 can down-modulate the activity of various promoters
    • Ginsberg, D., Mechta, F., Yaniv, M., and Oren, M. Wild-type p53 can down-modulate the activity of various promoters. Proc. Natl. Acad. Sci. USA, 88: 9979-9983, 1991.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 9979-9983
    • Ginsberg, D.1    Mechta, F.2    Yaniv, M.3    Oren, M.4
  • 15
    • 0026642078 scopus 로고
    • Inhibition of viral and cellular promoters by wild-type p53
    • Subler, M. A., Martin, D. W., and Deb, S. Inhibition of viral and cellular promoters by wild-type p53. J. Virol., 66: 4757-4762, 1992.
    • (1992) J. Virol. , vol.66 , pp. 4757-4762
    • Subler, M.A.1    Martin, D.W.2    Deb, S.3
  • 16
    • 0026702212 scopus 로고
    • (1992) Wild-type p53 mediates positive regulation of gene expression through a specific DNA sequence element
    • Zambetti, G. P., Bargonetti, J., Walker, K., Prives, C., and Levine, A. J. (1992) Wild-type p53 mediates positive regulation of gene expression through a specific DNA sequence element. Genes Dev., 6: 1143-1152, 1992.
    • (1992) Genes Dev. , vol.6 , pp. 1143-1152
    • Zambetti, G.P.1    Bargonetti, J.2    Walker, K.3    Prives, C.4    Levine, A.J.5
  • 17
    • 0025024469 scopus 로고
    • Presence of a potent transcription activating sequence in the p53 protein
    • Fields, S., and Jang, S. K. Presence of a potent transcription activating sequence in the p53 protein. Science (Washington DC), 249: 1046- 1049, 1990.
    • (1990) Science (Washington DC) , vol.249 , pp. 1046-1049
    • Fields, S.1    Jang, S.K.2
  • 18
    • 0025775929 scopus 로고
    • Repression of the interleukin 6 gene promoter by p53 and the retinoblastoma susceptibility gene product
    • Santhanam, U., Ray, A., and Sehgal, P. B. Repression of the interleukin 6 gene promoter by p53 and the retinoblastoma susceptibility gene product. Proc. Natl. Acad. Sci. USA, 88: 7605-7609, 1991.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 7605-7609
    • Santhanam, U.1    Ray, A.2    Sehgal, P.B.3
  • 19
    • 0026555717 scopus 로고
    • Modulation of activity of the promoter of the human MDR1 gene by Ras and p53
    • Chin, K. V., Ueda, K., Pastan, I., and Gottesman, M. M. Modulation of activity of the promoter of the human MDR1 gene by Ras and p53. Science (Washington DC), 255: 459-462, 1992.
    • (1992) Science (Washington DC) , vol.255 , pp. 459-462
    • Chin, K.V.1    Ueda, K.2    Pastan, I.3    Gottesman, M.M.4
  • 21
    • 0027251720 scopus 로고
    • Wild-type p53 mediates apoptosis by E1A, which is inhibited by E1B
    • Debbas, M., and White, E. Wild-type p53 mediates apoptosis by E1A, which is inhibited by E1B. Genes Dev., 7: 546-554, 1993.
    • (1993) Genes Dev. , vol.7 , pp. 546-554
    • Debbas, M.1    White, E.2
  • 22
    • 0027319521 scopus 로고
    • P53 is required for radiation-induced apoptosis in mouse thymocytes
    • Lowe, S. W., Schmitt, E. M., Smith, S. W., Osborne, B. A., and Jacks, T. p53 is required for radiation-induced apoptosis in mouse thymocytes. Nature (Lond.), 362: 847-849, 1993.
    • (1993) Nature (Lond.) , vol.362 , pp. 847-849
    • Lowe, S.W.1    Schmitt, E.M.2    Smith, S.W.3    Osborne, B.A.4    Jacks, T.5
  • 23
    • 0028883179 scopus 로고
    • Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
    • Miyashita, T., and Reed, J. C. Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell, 80: 293-299, 1995.
    • (1995) Cell , vol.80 , pp. 293-299
    • Miyashita, T.1    Reed, J.C.2
  • 25
    • 0025251915 scopus 로고
    • Domains required for in vitro association between cellular p53 and the adenovirus 2 E1B 55K protein
    • Kao, C. C., Yew, P. R., and Berk, A. J. Domains required for in vitro association between cellular p53 and the adenovirus 2 E1B 55K protein. Virology, 179: 806-814, 1990.
    • (1990) Virology , vol.179 , pp. 806-814
    • Kao, C.C.1    Yew, P.R.2    Berk, A.J.3
  • 26
    • 0026560315 scopus 로고
    • Inhibition of p53 transactivation required for transformation by adenovirus early region 1B protein
    • Yew, P. R., and Berk, A. J. Inhibition of p53 transactivation required for transformation by adenovirus early region 1B protein. Nature (Lond.), 357: 82-85, 1992.
    • (1992) Nature (Lond.) , vol.357 , pp. 82-85
    • Yew, P.R.1    Berk, A.J.2
  • 27
    • 0028089283 scopus 로고
    • Adenovirus E1A oncogene tethers a transcriptional repression domain to p53
    • Yew, P. R., Liu, X., and Berk, A. J. Adenovirus E1A oncogene tethers a transcriptional repression domain to p53. Genes Dev., 8: 190-202, 1994.
    • (1994) Genes Dev. , vol.8 , pp. 190-202
    • Yew, P.R.1    Liu, X.2    Berk, A.J.3
  • 28
    • 0029147167 scopus 로고
    • Adenovirus E1A proteins induce apoptosis by both p53-dependent and p53-independent mechanisms
    • Teodoro, J. G., Shore, G. C., and Branton, P. E. Adenovirus E1A proteins induce apoptosis by both p53-dependent and p53-independent mechanisms. Oncogene, 11: 467-474, 1995.
    • (1995) Oncogene , vol.11 , pp. 467-474
    • Teodoro, J.G.1    Shore, G.C.2    Branton, P.E.3
  • 29
    • 0027952802 scopus 로고
    • Phosphorylation at the carboxy terminus of the 55-kilodalton adenovirus type 5 E1B protein regulates transforming activity
    • Teodoro, J. G., Halliday, T., Whalen, S. G., Takayesu, D., Graham, F. L., and Branton, P. E. Phosphorylation at the carboxy terminus of the 55-kilodalton adenovirus type 5 E1B protein regulates transforming activity. J. Virol., 58: 776-786, 1994.
    • (1994) J. Virol. , vol.58 , pp. 776-786
    • Teodoro, J.G.1    Halliday, T.2    Whalen, S.G.3    Takayesu, D.4    Graham, F.L.5    Branton, P.E.6
  • 30
    • 0027451668 scopus 로고
    • p53- dependent apoptosis modulates the cytotoxicity of anticancer agents
    • Lowe, S. W., Ruley, H. E., Jacks, T., and Housman, D. E. p53- dependent apoptosis modulates the cytotoxicity of anticancer agents. Cell, 74: 957-967, 1993.
    • (1993) Cell , vol.74 , pp. 957-967
    • Lowe, S.W.1    Ruley, H.E.2    Jacks, T.3    Housman, D.E.4
  • 32
    • 0025611503 scopus 로고
    • Genetic mechanisms of tumor suppression by the human p53 gene
    • Chen, P. L., Chen, Y. M., Bookstein, R., and Lee, W. H. Genetic mechanisms of tumor suppression by the human p53 gene. Science (Washington DC), 250: 1576-1580, 1990.
    • (1990) Science (Washington DC) , vol.250 , pp. 1576-1580
    • Chen, P.L.1    Chen, Y.M.2    Bookstein, R.3    Lee, W.H.4
  • 33
    • 0029261994 scopus 로고
    • Apoptosis induced in human osteosarcoma cells is one of the mechanisms for the cytocidal effect of Ad5CMV-p53
    • Wang, J., Bucana, C. D., Roth, J. A., and Zhang, W. W. Apoptosis induced in human osteosarcoma cells is one of the mechanisms for the cytocidal effect of Ad5CMV-p53. Cancer Gene Therapy, 2: 9-17, 1995.
    • (1995) Cancer Gene Therapy , vol.2 , pp. 9-17
    • Wang, J.1    Bucana, C.D.2    Roth, J.A.3    Zhang, W.W.4
  • 34
    • 0028222955 scopus 로고
    • Bcl-2 blocks p53-dependent apoptosis
    • Chiou, S. K., Rao, L., and White, E. Bcl-2 blocks p53-dependent apoptosis. Mol. Cell. Biol., 14: 2556-2563, 1994.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 2556-2563
    • Chiou, S.K.1    Rao, L.2    White, E.3
  • 36
    • 0015383455 scopus 로고
    • Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
    • Kerr, J. F., Wyllie, A. H., and Currie, A. R. Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br. J. Cancer, 26: 239-257, 1972.
    • (1972) Br. J. Cancer , vol.26 , pp. 239-257
    • Kerr, J.F.1    Wyllie, A.H.2    Currie, A.R.3
  • 37
    • 0016774373 scopus 로고
    • An electron microscopic study of the mode of cell death induced by cancer-chemotherapeutic agents in populations of proliferating normal and neoplastic cells
    • Searle, J., Lawson, T. A., Abbott, P. J., Harmon, B., and Kerr, J. F. An electron microscopic study of the mode of cell death induced by cancer-chemotherapeutic agents in populations of proliferating normal and neoplastic cells. J. Pathol., 116: 129-138, 1975.
    • (1975) J. Pathol. , vol.116 , pp. 129-138
    • Searle, J.1    Lawson, T.A.2    Abbott, P.J.3    Harmon, B.4    Kerr, J.F.5
  • 38
    • 0028873247 scopus 로고
    • P53-independent apoptotic and necrotic cell deaths induced by adenovirus infection: Suppression by E1B 19K and Bcl-2 proteins
    • Subramanian, T., Tarodi, B., and Chinnadurai, G. p53-independent apoptotic and necrotic cell deaths induced by adenovirus infection: suppression by E1B 19K and Bcl-2 proteins. Cell Growth & Differ., 6: 131-137, 1995.
    • (1995) Cell Growth & Differ. , vol.6 , pp. 131-137
    • Subramanian, T.1    Tarodi, B.2    Chinnadurai, G.3
  • 39
  • 40
    • 0026773471 scopus 로고
    • The 19-kilodalton adenovirus E1B transforming protein inhibits programmed cell death and prevents cytolysis by tumor necrosis factor α
    • White, E., Sabbatini, P., Debbas, M., Wold, W. S. M., Kusher, D., and Gooding, L. R. The 19-kilodalton adenovirus E1B transforming protein inhibits programmed cell death and prevents cytolysis by tumor necrosis factor α. Mol. Cell. Biol., 12: 2570-2580, 1992.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 2570-2580
    • White, E.1    Sabbatini, P.2    Debbas, M.3    Wold, W.S.M.4    Kusher, D.5    Gooding, L.R.6
  • 41
    • 0026639932 scopus 로고
    • The adenovirus E1A proteins induce apoptosis, which is inhibited by the E1B 19 kDa and bcl-2 proteins
    • Rao, L., Debbas, M., Sabbatini, P., Hockenbery, D., Korsmeyer, S., and White, E. The adenovirus E1A proteins induce apoptosis, which is inhibited by the E1B 19 kDa and bcl-2 proteins. Proc. Natl. Acad. Sci. USA, 89: 7742-7746, 1992.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 7742-7746
    • Rao, L.1    Debbas, M.2    Sabbatini, P.3    Hockenbery, D.4    Korsmeyer, S.5    White, E.6
  • 43
    • 0028289951 scopus 로고
    • Role of the membrane anchor domain of Bcl-2 in suppression of apoptosis caused by E1B-defective adenovirus
    • Nguyen, M., Branton, P. E., Walton, P. A., Korsmeyer, S. J., and Shore, G. C. Role of the membrane anchor domain of Bcl-2 in suppression of apoptosis caused by E1B-defective adenovirus. J. Biol. Chem., 269: 16521-16524, 1994.
    • (1994) J. Biol. Chem. , vol.269 , pp. 16521-16524
    • Nguyen, M.1    Branton, P.E.2    Walton, P.A.3    Korsmeyer, S.J.4    Shore, G.C.5
  • 44
    • 0027996899 scopus 로고
    • Gene regulation by temperature sensitive p53 mutants: Identification of p53 response
    • Buckbinder, L., Talbott, R., Seizinger, B. R., and Kley, N. Gene regulation by temperature sensitive p53 mutants: identification of p53 response. Proc. Natl. Acad. Sci. USA, 91: 10640-10644, 1994.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 10640-10644
    • Buckbinder, L.1    Talbott, R.2    Seizinger, B.R.3    Kley, N.4
  • 45
    • 0028337504 scopus 로고
    • Terminal differentiation and apoptosis in experimental lung metastases of human osteogenic sarcoma cells by wild type p53
    • Radinsky, R., Fidler, I. J., Price, J. E., Esumi, N., Tsan, R., Petty, C. M., Bucana, C. D., and Bar-Eli, M. Terminal differentiation and apoptosis in experimental lung metastases of human osteogenic sarcoma cells by wild type p53. Oncogene, 9: 1877-1883, 1994.
    • (1994) Oncogene , vol.9 , pp. 1877-1883
    • Radinsky, R.1    Fidler, I.J.2    Price, J.E.3    Esumi, N.4    Tsan, R.5    Petty, C.M.6    Bucana, C.D.7    Bar-Eli, M.8
  • 46
    • 11944252783 scopus 로고
    • A human temperature-sensitive p53 mutant p53Val-138: Modulation of the cell cycle, viability and expression of p53-responsive genes
    • Yamato, K., Yamamoto, M., Hirano, Y., and Tsuchida, N. A human temperature-sensitive p53 mutant p53Val-138: modulation of the cell cycle, viability and expression of p53-responsive genes. Oncogene, 11: 1-6, 1995.
    • (1995) Oncogene , vol.11 , pp. 1-6
    • Yamato, K.1    Yamamoto, M.2    Hirano, Y.3    Tsuchida, N.4
  • 47
    • 0029164446 scopus 로고
    • The WT1 gene product stabilizes p53 and inhibits p53-mediated apoptosis
    • Maheswaran, S., Englert, C., Bennett, P., Heinrich, G., and Haber, D. A. The WT1 gene product stabilizes p53 and inhibits p53-mediated apoptosis. Genes Dev., 9: 2143-2156, 1995.
    • (1995) Genes Dev. , vol.9 , pp. 2143-2156
    • Maheswaran, S.1    Englert, C.2    Bennett, P.3    Heinrich, G.4    Haber, D.A.5
  • 49
    • 0029261994 scopus 로고
    • Apoptosis induced in human osteosarcoma cells is one of the mechanisms for the cytocidal effect of Ad5CMV-p53
    • Wang, J., Bucana, C. D., Roth, J. A., and Zhang, W. W. Apoptosis induced in human osteosarcoma cells is one of the mechanisms for the cytocidal effect of Ad5CMV-p53. Cancer Gene Ther., 2: 9-17, 1995.
    • (1995) Cancer Gene Ther. , vol.2 , pp. 9-17
    • Wang, J.1    Bucana, C.D.2    Roth, J.A.3    Zhang, W.W.4
  • 50
    • 0027934570 scopus 로고
    • P53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens
    • Morgenbesser, S. D., Williams, B. O., Jacks, T., and DePinho, R. A. p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens. Nature (Lond.), 371: 72-74, 1994.
    • (1994) Nature (Lond.) , vol.371 , pp. 72-74
    • Morgenbesser, S.D.1    Williams, B.O.2    Jacks, T.3    Depinho, R.A.4
  • 51
    • 0026004857 scopus 로고
    • Transcriptional activation by viral regulatory proteins
    • Nevins, J. R. Transcriptional activation by viral regulatory proteins. Trends Biochem. Sci., 16: 35-439, 1991.
    • (1991) Trends Biochem. Sci. , vol.16 , pp. 35-439
    • Nevins, J.R.1
  • 52
    • 0028149786 scopus 로고
    • Checkpoints of duelling dimers foil death wishes
    • Oltvai, Z. N., and Korsmeyer, S. J. Checkpoints of duelling dimers foil death wishes. Cell, 79: 189-192, 1994.
    • (1994) Cell , vol.79 , pp. 189-192
    • Oltvai, Z.N.1    Korsmeyer, S.J.2
  • 53
    • 0019817902 scopus 로고
    • Degradation of intracellular DNA in KB cells infected with cyt mutants of human adenovirus type 12
    • Ezoe, H., Lai Fatt, R. B., and Mak, S. Degradation of intracellular DNA in KB cells infected with cyt mutants of human adenovirus type 12. J. Virol., 40: 20-27, 1981.
    • (1981) J. Virol. , vol.40 , pp. 20-27
    • Ezoe, H.1    Lai Fatt, R.B.2    Mak, S.3
  • 54
    • 0021739589 scopus 로고
    • Deletion of the gene encoding the adenovirus 5 early region 1b 21,000-molecular-weight polypeptide leads to degradation of viral and host cell DNA
    • Pilder, S., Logan, J., and Shenk, T. Deletion of the gene encoding the adenovirus 5 early region 1b 21,000-molecular-weight polypeptide leads to degradation of viral and host cell DNA. J. Virol., 52: 664-671, 1984.
    • (1984) J. Virol. , vol.52 , pp. 664-671
    • Pilder, S.1    Logan, J.2    Shenk, T.3
  • 55
    • 0021184793 scopus 로고
    • 19 kDa tumor antigen coded by early region E1b of adenovirus 2 is required for efficient synthesis and for protection of viral DNA
    • Subramanian, T., Kuppuswamy, M., Gysbers, J., Mak, S., and Chinnadurai, G. 19 kDa tumor antigen coded by early region E1b of adenovirus 2 is required for efficient synthesis and for protection of viral DNA. J. Biol. Chem., 259: 11777-11783, 1984.
    • (1984) J. Biol. Chem. , vol.259 , pp. 11777-11783
    • Subramanian, T.1    Kuppuswamy, M.2    Gysbers, J.3    Mak, S.4    Chinnadurai, G.5
  • 56
    • 0026049728 scopus 로고
    • Adenovirus E1B 19-kilodalton protein overcomes the cytotoxicity of E1A proteins
    • White, E., Cipriani, R., Sabbatini, P., and Denton, A. Adenovirus E1B 19-kilodalton protein overcomes the cytotoxicity of E1A proteins. J. Virol., 65: 2968-2978, 1991.
    • (1991) J. Virol. , vol.65 , pp. 2968-2978
    • White, E.1    Cipriani, R.2    Sabbatini, P.3    Denton, A.4
  • 57
    • 0020609657 scopus 로고
    • Intracellular localization of adenovirus type 5 tumor antigens in productively infected cells
    • Rowe, D. T., Graham, F. L., and Branton, P. E. Intracellular localization of adenovirus type 5 tumor antigens in productively infected cells. Virology, 129: 456-468, 1983.
    • (1983) Virology , vol.129 , pp. 456-468
    • Rowe, D.T.1    Graham, F.L.2    Branton, P.E.3
  • 58
    • 0027448548 scopus 로고
    • Inhibition of cell proliferation by an adenovirus vector expressing the human wild type p53 protein
    • Bacchetti, S., and Graham, F. L. Inhibition of cell proliferation by an adenovirus vector expressing the human wild type p53 protein. Int. J. Oncol., 78: 781-788, 1993.
    • (1993) Int. J. Oncol. , vol.78 , pp. 781-788
    • Bacchetti, S.1    Graham, F.L.2
  • 59
    • 0015847039 scopus 로고
    • A new technique for the assay of infectivity of human adenovirus 5 DNA
    • Graham, F. L., and van der Eb, A. J. A new technique for the assay of infectivity of human adenovirus 5 DNA. Virology, 52: 456-467, 1972.
    • (1972) Virology , vol.52 , pp. 456-467
    • Graham, F.L.1    Van der Eb, A.J.2
  • 60
    • 0025204548 scopus 로고
    • Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death
    • Hockenbery, D., Nunez, G., Milliman, C., Schreiber, R. D., and Korsmeyer, S. J. Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature (Lond.), 343: 334-336, 1990.
    • (1990) Nature (Lond.) , vol.343 , pp. 334-336
    • Hockenbery, D.1    Nunez, G.2    Milliman, C.3    Schreiber, R.D.4    Korsmeyer, S.J.5
  • 61
    • 0022483186 scopus 로고
    • Isolation of human- p53-specific monoclonal antibodies and their use in the studies of p53 expression
    • Banks, L., Matlashewski, G., and Crawford, L. Isolation of human- p53-specific monoclonal antibodies and their use in the studies of p53 expression. Eur. J. Biochem., 159: 529-534, 1986.
    • (1986) Eur. J. Biochem. , vol.159 , pp. 529-534
    • Banks, L.1    Matlashewski, G.2    Crawford, L.3
  • 63
    • 0026448672 scopus 로고
    • Regulation of the specific DNA function of p53
    • Hupp, T. R., Meek, D. W., Midgley, C. A., and Lane, D. P. Regulation of the specific DNA function of p53. Cell, 71: 875-86, 1992.
    • (1992) Cell , vol.71 , pp. 875-886
    • Hupp, T.R.1    Meek, D.W.2    Midgley, C.A.3    Lane, D.P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.