Betulin induces mitochondrial cytochrome c release associated apoptosis in human cancer cells

Molecular Carcinogenesis

Volumn 49, Issue 7, 2010, Pages 630-640

  Li, Yang ^a,b   He, Kan ^a,b   Huang, Yinghui ^a   Zheng, Daxin ^a   Gao, Chang ^a,b   Cui, Lin ^a,b   Jin, Ying Hua ^a,b  

^a JILIN UNIVERSITY   (China)

^b Jilin University   (China)

Author keywords

Apoptosis; Bak; Bax; Betulin; Cytochrome c; Smac

Indexed keywords

BETULIC ACID; BETULIN; CASPASE 3; CASPASE 7; CASPASE 9; CYTOCHROME C; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAK; PROTEIN BAX; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; SMALL INTERFERING RNA;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BREAST CANCER; CANCER CELL; CELL STRAIN A549; CELL STRAIN HEPG2; CELL STRAIN K 562; CELL STRAIN NCI H460; CELL STRAIN PC 3; CELL VIABILITY; CONTROLLED STUDY; DRUG CYTOTOXICITY; ENZYME RELEASE; HELA CELL; HUMAN; HUMAN CELL; IC 50; IMMUNOBLOTTING; MITOCHONDRIAL MEMBRANE POTENTIAL; PRIORITY JOURNAL; RNA INTERFERENCE;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BCL-2 HOMOLOGOUS ANTAGONIST-KILLER PROTEIN; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; CASPASE 7; CASPASE 9; CELL LINE, TUMOR; CELL SURVIVAL; CYTOCHROMES C; HELA CELLS; HEP G2 CELLS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; K562 CELLS; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; NEOPLASMS; TRITERPENES;

EID: 77954488236     PISSN: 08991987     EISSN: 10982744     Source Type: Journal    
DOI: 10.1002/mc.20638     Document Type: Article

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