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Volumn 45, Issue 2, 2012, Pages 176-187

A new development of triterpene acid-containing extracts from Viscum album L. displays synergistic induction of apoptosis in acute lymphoblastic leukaemia

Author keywords

[No Author keywords available]

Indexed keywords

ANTILEUKEMIC AGENT; CASPASE 8; CASPASE 9; CYCLODEXTRIN; LIPOCORTIN 5; TRITERPENE DERIVATIVE; VISCUM ALBUM EXTRACT; VISCUM ALBUM LECTIN;

EID: 84857624883     PISSN: 09607722     EISSN: 13652184     Source Type: Journal    
DOI: 10.1111/j.1365-2184.2011.00801.x     Document Type: Article
Times cited : (39)

References (69)
  • 1
    • 0033877281 scopus 로고    scopus 로고
    • Survival of glioma patients after complementary treatment with galactoside-specific lectin from mistletoe
    • Lenartz D, Dott U, Menzel J, Schierholz JM, Beuth J (2000) Survival of glioma patients after complementary treatment with galactoside-specific lectin from mistletoe. Anticancer Res.20, 2073-2076.
    • (2000) Anticancer Res. , vol.20 , pp. 2073-2076
    • Lenartz, D.1    Dott, U.2    Menzel, J.3    Schierholz, J.M.4    Beuth, J.5
  • 3
    • 0022974278 scopus 로고
    • Immunomodulatory effects of iscador: a Viscum album preparation
    • Hajto T (1986) Immunomodulatory effects of iscador: a Viscum album preparation. Oncology43(Suppl. 1), 51-65.
    • (1986) Oncology , vol.43 , Issue.SUPPL. 1 , pp. 51-65
    • Hajto, T.1
  • 4
    • 38049015487 scopus 로고    scopus 로고
    • Low-dose mistletoe lectin-I reduces melanoma growth and spread in a SCID mouse xenograft model
    • Thies A, Dautel P, Meyer A, Pfuller U, Schumacher U (2008) Low-dose mistletoe lectin-I reduces melanoma growth and spread in a SCID mouse xenograft model. Br. J. Cancer98, 106-112.
    • (2008) Br. J. Cancer , vol.98 , pp. 106-112
    • Thies, A.1    Dautel, P.2    Meyer, A.3    Pfuller, U.4    Schumacher, U.5
  • 5
    • 47349093062 scopus 로고    scopus 로고
    • Induction of maturation and activation of human dendritic cells: a mechanism underlying the beneficial effect of Viscum album as complimentary therapy in cancer
    • Elluru SR, Van Huyen JP, Delignat S, Kazatchkine MD, Friboulet A, Kaveri SVet al. (2008) Induction of maturation and activation of human dendritic cells: a mechanism underlying the beneficial effect of Viscum album as complimentary therapy in cancer. BMC Cancer8, 161.
    • (2008) BMC Cancer , vol.8 , pp. 161
    • Elluru, S.R.1    Van Huyen, J.P.2    Delignat, S.3    Kazatchkine, M.D.4    Friboulet, A.5    Kaveri, S.V.6
  • 6
    • 27744562512 scopus 로고    scopus 로고
    • Mistletoe treatment induces GM-CSF- and IL-5 production by PBMC and increases blood granulocyte- and eosinophil counts: a placebo controlled randomized study in healthy subjects
    • Huber R, Rostock M, Goedl R, Ludtke R, Urech K, Buck Set al. (2005) Mistletoe treatment induces GM-CSF- and IL-5 production by PBMC and increases blood granulocyte- and eosinophil counts: a placebo controlled randomized study in healthy subjects. Eur. J. Med. Res.10, 411-418.
    • (2005) Eur. J. Med. Res. , vol.10 , pp. 411-418
    • Huber, R.1    Rostock, M.2    Goedl, R.3    Ludtke, R.4    Urech, K.5    Buck, S.6
  • 7
    • 0032929044 scopus 로고    scopus 로고
    • Cytotoxic effects of the components in heat-treated mistletoe (Viscum album)
    • Park JH, Hyun CK, Shin HK (1999) Cytotoxic effects of the components in heat-treated mistletoe (Viscum album). Cancer Lett.139, 207-213.
    • (1999) Cancer Lett. , vol.139 , pp. 207-213
    • Park, J.H.1    Hyun, C.K.2    Shin, H.K.3
  • 8
    • 0028150913 scopus 로고
    • Viscum album L. extracts reduce sister chromatid exchanges in cultured peripheral blood mononuclear cells
    • Bussing A, Azhari T, Ostendorp H, Lehnert A, Schweizer K (1994) Viscum album L. extracts reduce sister chromatid exchanges in cultured peripheral blood mononuclear cells. Eur. J. Cancer30A, 1836-1841.
    • (1994) Eur. J. Cancer , vol.30 , pp. 1836-1841
    • Bussing, A.1    Azhari, T.2    Ostendorp, H.3    Lehnert, A.4    Schweizer, K.5
  • 9
  • 10
    • 84857635349 scopus 로고    scopus 로고
    • Biological and pharmacological properties of Viscum album L. Mistletoe-The Genus Viscum Amsterdam: Harwood Academic Publishers.
    • Bussing A (2000) Biological and pharmacological properties of Viscum album L. Mistletoe-The Genus Viscum, p. 123-182. Amsterdam: Harwood Academic Publishers.
    • (2000) , pp. 123-182
    • Bussing, A.1
  • 11
    • 0031726081 scopus 로고    scopus 로고
    • Viscotoxin composition of the three European subspecies of Viscum album
    • Schaller G, Urech K, Grazi G, Giannattasio M (1998) Viscotoxin composition of the three European subspecies of Viscum album. Planta Med.64, 677-678.
    • (1998) Planta Med. , vol.64 , pp. 677-678
    • Schaller, G.1    Urech, K.2    Grazi, G.3    Giannattasio, M.4
  • 12
    • 33748652065 scopus 로고    scopus 로고
    • Viscotoxins, mistletoe lectins and their isoforms in mistletoe (Viscum album L.) extracts Iscador
    • Urech K, Schaller G, Jaggy C (2006) Viscotoxins, mistletoe lectins and their isoforms in mistletoe (Viscum album L.) extracts Iscador. Arzneimittelforschung56, 428-434.
    • (2006) Arzneimittelforschung , vol.56 , pp. 428-434
    • Urech, K.1    Schaller, G.2    Jaggy, C.3
  • 13
    • 0033662221 scopus 로고    scopus 로고
    • Biological effects of natural and recombinant mistletoe lectin and an aqueous mistletoe extract on human monocytes and lymphocytes in vitro
    • Elsasser-Beile U, Voss M, Schuhle R, Wetterauer U (2000) Biological effects of natural and recombinant mistletoe lectin and an aqueous mistletoe extract on human monocytes and lymphocytes in vitro. J. Clin. Lab. Anal.14, 255-259.
    • (2000) J. Clin. Lab. Anal. , vol.14 , pp. 255-259
    • Elsasser-Beile, U.1    Voss, M.2    Schuhle, R.3    Wetterauer, U.4
  • 16
    • 0022974277 scopus 로고
    • Mistletoe lectins and their A and B chains
    • Franz H (1986) Mistletoe lectins and their A and B chains. Oncology43(Suppl. 1), 23-34.
    • (1986) Oncology , vol.43 , Issue.SUPPL. 1 , pp. 23-34
    • Franz, H.1
  • 17
    • 0019566398 scopus 로고
    • Isolation and properties of three lectins from mistletoe (Viscum album L.)
    • Franz H, Ziska P, Kindt A (1981) Isolation and properties of three lectins from mistletoe (Viscum album L.). Biochem. J.195, 481-484.
    • (1981) Biochem. J. , vol.195 , pp. 481-484
    • Franz, H.1    Ziska, P.2    Kindt, A.3
  • 18
    • 0037186350 scopus 로고    scopus 로고
    • The cytotoxic effect of mistletoe lectins I, II and III on sensitive and multidrug resistant human colon cancer cell lines in vitro
    • Valentiner U, Pfuller U, Baum C, Schumacher U (2002) The cytotoxic effect of mistletoe lectins I, II and III on sensitive and multidrug resistant human colon cancer cell lines in vitro. Toxicology171, 187-199.
    • (2002) Toxicology , vol.171 , pp. 187-199
    • Valentiner, U.1    Pfuller, U.2    Baum, C.3    Schumacher, U.4
  • 19
    • 25844444123 scopus 로고    scopus 로고
    • Oncopharmacological perspectives of a Plant Lectin (Viscum album Agglutinin-I): overview of recent results from in vitro experiments and in vivo animal models, and their possible relevance for clinical applications
    • Hajto T, Hostanska K, Berki T, Palinkas L, Boldizsar F, Nemeth P (2005) Oncopharmacological perspectives of a Plant Lectin (Viscum album Agglutinin-I): overview of recent results from in vitro experiments and in vivo animal models, and their possible relevance for clinical applications. Evid. Based. Complement Alternat. Med.2, 59-67.
    • (2005) Evid. Based. Complement Alternat. Med. , vol.2 , pp. 59-67
    • Hajto, T.1    Hostanska, K.2    Berki, T.3    Palinkas, L.4    Boldizsar, F.5    Nemeth, P.6
  • 20
    • 0025297360 scopus 로고
    • Characterization of cytotoxic proteins from mistletoe (Viscum album L.)
    • Jung ML, Baudino S, Ribereau-Gayon G, Beck JP (1990) Characterization of cytotoxic proteins from mistletoe (Viscum album L.). Cancer Lett.51, 103-108.
    • (1990) Cancer Lett. , vol.51 , pp. 103-108
    • Jung, M.L.1    Baudino, S.2    Ribereau-Gayon, G.3    Beck, J.P.4
  • 21
    • 0342978068 scopus 로고    scopus 로고
    • Expression of mitochondrial Apo2.7 molecules and caspase-3 activation in human lymphocytes treated with the ribosome-inhibiting mistletoe lectins and the cell membrane permeabilizing viscotoxins
    • Bussing A, Vervecken W, Wagner M, Wagner B, Pfuller U, Schietzel M (1999) Expression of mitochondrial Apo2.7 molecules and caspase-3 activation in human lymphocytes treated with the ribosome-inhibiting mistletoe lectins and the cell membrane permeabilizing viscotoxins. Cytometry37, 133-139.
    • (1999) Cytometry , vol.37 , pp. 133-139
    • Bussing, A.1    Vervecken, W.2    Wagner, M.3    Wagner, B.4    Pfuller, U.5    Schietzel, M.6
  • 22
    • 0042608534 scopus 로고    scopus 로고
    • Induction of apoptosis in human lymphocytes treated with Viscum album L. is mediated by the mistletoe lectins
    • Bussing A, Suzart K, Bergmann J, Pfuller U, Schietzel M, Schweizer K (1996) Induction of apoptosis in human lymphocytes treated with Viscum album L. is mediated by the mistletoe lectins. Cancer Lett.99, 59-72.
    • (1996) Cancer Lett. , vol.99 , pp. 59-72
    • Bussing, A.1    Suzart, K.2    Bergmann, J.3    Pfuller, U.4    Schietzel, M.5    Schweizer, K.6
  • 23
    • 0035293795 scopus 로고    scopus 로고
    • Involvement of caspase-3 in apoptosis induced by Viscum album var. coloratum agglutinin in HL-60 cells
    • Lyu SY, Park WB, Choi KH, Kim WH (2001) Involvement of caspase-3 in apoptosis induced by Viscum album var. coloratum agglutinin in HL-60 cells. Biosci. Biotechnol. Biochem.65, 534-541.
    • (2001) Biosci. Biotechnol. Biochem. , vol.65 , pp. 534-541
    • Lyu, S.Y.1    Park, W.B.2    Choi, K.H.3    Kim, W.H.4
  • 24
    • 0033135490 scopus 로고    scopus 로고
    • Mistletoe lectin activates caspase-8/FLICE independently of death receptor signaling and enhances anticancer drug-induced apoptosis
    • Bantel H, Engels IH, Voelter W, Schulze-Osthoff K, Wesselborg S (1999) Mistletoe lectin activates caspase-8/FLICE independently of death receptor signaling and enhances anticancer drug-induced apoptosis. Cancer Res.59, 2083-2090.
    • (1999) Cancer Res. , vol.59 , pp. 2083-2090
    • Bantel, H.1    Engels, I.H.2    Voelter, W.3    Schulze-Osthoff, K.4    Wesselborg, S.5
  • 25
    • 43049176801 scopus 로고    scopus 로고
    • Molecular mechanisms of mistletoe plant extract-induced apoptosis in acute lymphoblastic leukemia in vivo and in vitro
    • Seifert G, Jesse P, Laengler A, Reindl T, Luth M, Lobitz Set al. (2008) Molecular mechanisms of mistletoe plant extract-induced apoptosis in acute lymphoblastic leukemia in vivo and in vitro. Cancer Lett.264, 218-228.
    • (2008) Cancer Lett. , vol.264 , pp. 218-228
    • Seifert, G.1    Jesse, P.2    Laengler, A.3    Reindl, T.4    Luth, M.5    Lobitz, S.6
  • 27
    • 74049157757 scopus 로고    scopus 로고
    • Pentacyclic triterpenes of the lupane, oleanane and ursane group as tools in cancer therapy
    • Laszczyk MN (2009) Pentacyclic triterpenes of the lupane, oleanane and ursane group as tools in cancer therapy. Planta Med.75, 1549-1560.
    • (2009) Planta Med. , vol.75 , pp. 1549-1560
    • Laszczyk, M.N.1
  • 28
    • 34250302748 scopus 로고    scopus 로고
    • Solubility studies of oleanolic acid and betulinic acid in aqueous solutions and plant extracts of Viscum album L
    • Jager S, Winkler K, Pfuller U, Scheffler A (2007) Solubility studies of oleanolic acid and betulinic acid in aqueous solutions and plant extracts of Viscum album L. Planta Med.73, 157-162.
    • (2007) Planta Med. , vol.73 , pp. 157-162
    • Jager, S.1    Winkler, K.2    Pfuller, U.3    Scheffler, A.4
  • 29
    • 8444253806 scopus 로고    scopus 로고
    • Pentacyclic triterpenoic acids: new chemoprotective compounds. Minireview
    • Ovesna Z, Vachalkova A, Horvathova K, Tothova D (2004) Pentacyclic triterpenoic acids: new chemoprotective compounds. Minireview. Neoplasma51, 327-333.
    • (2004) Neoplasma , vol.51 , pp. 327-333
    • Ovesna, Z.1    Vachalkova, A.2    Horvathova, K.3    Tothova, D.4
  • 30
    • 0027982986 scopus 로고
    • Inhibition of skin tumorigenesis by rosemary and its constituents carnosol and ursolic acid
    • Huang MT, Ho CT, Wang ZY, Ferraro T, Lou YR, Stauber Ket al. (1994) Inhibition of skin tumorigenesis by rosemary and its constituents carnosol and ursolic acid. Cancer Res.54, 701-708.
    • (1994) Cancer Res. , vol.54 , pp. 701-708
    • Huang, M.T.1    Ho, C.T.2    Wang, Z.Y.3    Ferraro, T.4    Lou, Y.R.5    Stauber, K.6
  • 31
    • 0031440035 scopus 로고    scopus 로고
    • Anti-inflammatory actions of pentacyclic triterpenes
    • Safayhi H, Sailer ER (1997) Anti-inflammatory actions of pentacyclic triterpenes. Planta Med.63, 487-493.
    • (1997) Planta Med. , vol.63 , pp. 487-493
    • Safayhi, H.1    Sailer, E.R.2
  • 32
    • 0033646961 scopus 로고    scopus 로고
    • Betulinic acid induces apoptosis through a direct effect on mitochondria in neuroectodermal tumors
    • Fulda S, Debatin KM (2000) Betulinic acid induces apoptosis through a direct effect on mitochondria in neuroectodermal tumors. Med. Pediatr. Oncol.35, 616-618.
    • (2000) Med. Pediatr. Oncol. , vol.35 , pp. 616-618
    • Fulda, S.1    Debatin, K.M.2
  • 33
    • 0033937785 scopus 로고    scopus 로고
    • Epicuticular waxes and flavonol aglycones of the European mistletoe, Viscum album L
    • Wollenweber E, Wieland A, Haas K (2000) Epicuticular waxes and flavonol aglycones of the European mistletoe, Viscum album L. Z. Naturforsch. C.55, 314-317.
    • (2000) Z. Naturforsch. C. , vol.55 , pp. 314-317
    • Wollenweber, E.1    Wieland, A.2    Haas, K.3
  • 34
    • 0033584217 scopus 로고    scopus 로고
    • Synthesis and evaluation of potential complement inhibitory semisynthetic analogs of oleanolic acid
    • Assefa H, Nimrod A, Walker L, Sindelar R (1999) Synthesis and evaluation of potential complement inhibitory semisynthetic analogs of oleanolic acid. Bioorg. Med. Chem. Lett.9, 1889-1894.
    • (1999) Bioorg. Med. Chem. Lett. , vol.9 , pp. 1889-1894
    • Assefa, H.1    Nimrod, A.2    Walker, L.3    Sindelar, R.4
  • 35
    • 65549127616 scopus 로고    scopus 로고
    • Oleanane triterpenoid CDDO-Me inhibits growth and induces apoptosis in prostate cancer cells by independently targeting pro-survival Akt and mTOR
    • Deeb D, Gao X, Jiang H, Dulchavsky SA, Gautam SC (2009) Oleanane triterpenoid CDDO-Me inhibits growth and induces apoptosis in prostate cancer cells by independently targeting pro-survival Akt and mTOR. Prostate69, 851-860.
    • (2009) Prostate , vol.69 , pp. 851-860
    • Deeb, D.1    Gao, X.2    Jiang, H.3    Dulchavsky, S.A.4    Gautam, S.C.5
  • 36
    • 70449651686 scopus 로고    scopus 로고
    • Oleanane triterpenoid CDDO-Me inhibits growth and induces apoptosis in prostate cancer cells through a ROS-dependent mechanism
    • Deeb D, Gao X, Jiang H, Janic B, Arbab AS, Rojanasakul Yet al. (2010) Oleanane triterpenoid CDDO-Me inhibits growth and induces apoptosis in prostate cancer cells through a ROS-dependent mechanism. Biochem. Pharmacol.79, 350-360.
    • (2010) Biochem. Pharmacol. , vol.79 , pp. 350-360
    • Deeb, D.1    Gao, X.2    Jiang, H.3    Janic, B.4    Arbab, A.S.5    Rojanasakul, Y.6
  • 37
    • 34547621658 scopus 로고    scopus 로고
    • Synthetic triterpenoids inhibit growth and induce apoptosis in human glioblastoma and neuroblastoma cells through inhibition of prosurvival Akt, NF-kappaB and Notch1 signaling
    • Gao X, Deeb D, Jiang H, Liu Y, Dulchavsky SA, Gautam SC (2007) Synthetic triterpenoids inhibit growth and induce apoptosis in human glioblastoma and neuroblastoma cells through inhibition of prosurvival Akt, NF-kappaB and Notch1 signaling. J. Neurooncol.84, 147-157.
    • (2007) J. Neurooncol. , vol.84 , pp. 147-157
    • Gao, X.1    Deeb, D.2    Jiang, H.3    Liu, Y.4    Dulchavsky, S.A.5    Gautam, S.C.6
  • 38
    • 11144352711 scopus 로고    scopus 로고
    • Apoptosis inducing activity of viscin, a lipophilic extract from Viscum album L
    • Urech K, Scher JM, Hostanska K, Becker H (2005) Apoptosis inducing activity of viscin, a lipophilic extract from Viscum album L. J. Pharm. Pharmacol.57, 101-109.
    • (2005) J. Pharm. Pharmacol. , vol.57 , pp. 101-109
    • Urech, K.1    Scher, J.M.2    Hostanska, K.3    Becker, H.4
  • 39
    • 75549090973 scopus 로고    scopus 로고
    • The influence of cosolvent on the complexation of HP-beta-cyclodextrins with oleanolic acid and ursolic acid
    • Li R, Quan P, Liu DF, Wei FD, Zhang Q, Xu QW (2009) The influence of cosolvent on the complexation of HP-beta-cyclodextrins with oleanolic acid and ursolic acid. AAPS PharmSciTech.10, 1137-1144.
    • (2009) AAPS PharmSciTech. , vol.10 , pp. 1137-1144
    • Li, R.1    Quan, P.2    Liu, D.F.3    Wei, F.D.4    Zhang, Q.5    Xu, Q.W.6
  • 40
    • 0043128840 scopus 로고    scopus 로고
    • Studies on the non-covalent complexes between oleanolic acid and cyclodextrins using electrospray ionization tandem mass spectrometry
    • Guo M, Zhang S, Song F, Wang D, Liu Z, Liu S (2003) Studies on the non-covalent complexes between oleanolic acid and cyclodextrins using electrospray ionization tandem mass spectrometry. J. Mass Spectrom.38, 723-731.
    • (2003) J. Mass Spectrom. , vol.38 , pp. 723-731
    • Guo, M.1    Zhang, S.2    Song, F.3    Wang, D.4    Liu, Z.5    Liu, S.6
  • 41
    • 67649836518 scopus 로고    scopus 로고
    • Pentacyclic triterpene distribution in various plants - rich sources for a new group of multi-potent plant extracts
    • Jager S, Trojan H, Kopp T, Laszczyk MN, Scheffler A (2009) Pentacyclic triterpene distribution in various plants - rich sources for a new group of multi-potent plant extracts. Molecules14, 2016-2031.
    • (2009) Molecules , vol.14 , pp. 2016-2031
    • Jager, S.1    Trojan, H.2    Kopp, T.3    Laszczyk, M.N.4    Scheffler, A.5
  • 42
    • 44149104317 scopus 로고    scopus 로고
    • Membrane interactions of ternary phospholipid/cholesterol bilayers and encapsulation efficiencies of a RIP II protein
    • Manojlovic V, Winkler K, Bunjes V, Neub A, Schubert R, Bugarski Bet al. (2008) Membrane interactions of ternary phospholipid/cholesterol bilayers and encapsulation efficiencies of a RIP II protein. Colloids Surf. B Biointerfaces64, 284-296.
    • (2008) Colloids Surf. B Biointerfaces , vol.64 , pp. 284-296
    • Manojlovic, V.1    Winkler, K.2    Bunjes, V.3    Neub, A.4    Schubert, R.5    Bugarski, B.6
  • 43
    • 79952933292 scopus 로고    scopus 로고
    • Preparation of herbal tea as infusion or by maceration at room temperature using mistletoe tea as an example
    • Jager S, Beffert M, Hoppe K, Nadberezny D, Frank B, Scheffler A (2011) Preparation of herbal tea as infusion or by maceration at room temperature using mistletoe tea as an example. Scientia Pharmaceutica79, 145-155.
    • (2011) Scientia Pharmaceutica , vol.79 , pp. 145-155
    • Jager, S.1    Beffert, M.2    Hoppe, K.3    Nadberezny, D.4    Frank, B.5    Scheffler, A.6
  • 44
    • 74549165964 scopus 로고    scopus 로고
    • Compound K, a metabolite of ginseng saponin, induces apoptosis via caspase-8-dependent pathway in HL-60 human leukemia cells
    • Cho SH, Chung KS, Choi JH, Kim DH, Lee KT (2009) Compound K, a metabolite of ginseng saponin, induces apoptosis via caspase-8-dependent pathway in HL-60 human leukemia cells. BMC Cancer9, 449.
    • (2009) BMC Cancer , vol.9 , pp. 449
    • Cho, S.H.1    Chung, K.S.2    Choi, J.H.3    Kim, D.H.4    Lee, K.T.5
  • 45
  • 46
    • 0034442778 scopus 로고    scopus 로고
    • Activation of caspase cascades in Korean mistletoe (Viscum album var. coloratum) lectin-II-induced apoptosis of human myeloleukemic U937 cells
    • Kim MS, So HS, Lee KM, Park JS, Lee JH, Moon SKet al. (2000) Activation of caspase cascades in Korean mistletoe (Viscum album var. coloratum) lectin-II-induced apoptosis of human myeloleukemic U937 cells. Gen. Pharmacol.34, 349-355.
    • (2000) Gen. Pharmacol. , vol.34 , pp. 349-355
    • Kim, M.S.1    So, H.S.2    Lee, K.M.3    Park, J.S.4    Lee, J.H.5    Moon, S.K.6
  • 47
    • 0001458215 scopus 로고
    • Effect of more than one inhibitor
    • 488-512. New York: Academic Press.
    • Webb RJ (1963) Effect of more than one inhibitor. In: Enzyme and Metabolic Inhibitors, Vol. 1, 66-79, 488-512. New York: Academic Press.
    • (1963) Enzyme and Metabolic Inhibitors , vol.1 , pp. 66-79
    • Webb, R.J.1
  • 49
    • 0346753573 scopus 로고    scopus 로고
    • Comparative study of the sensitivity of lymphoblastoid and transformed monocytic cell lines to the cytotoxic effects of Viscum album extracts of different origin
    • Duong Van Huyen JP, Delignat S, Kazatchkine MD, Kaveri SV (2003) Comparative study of the sensitivity of lymphoblastoid and transformed monocytic cell lines to the cytotoxic effects of Viscum album extracts of different origin. Chemotherapy49, 298-302.
    • (2003) Chemotherapy , vol.49 , pp. 298-302
    • Duong Van Huyen, J.P.1    Delignat, S.2    Kazatchkine, M.D.3    Kaveri, S.V.4
  • 50
    • 0038489424 scopus 로고    scopus 로고
    • Involvement of hydrogen peroxide in mistletoe lectin-II-induced apoptosis of myeloleukemic U937 cells
    • Kim MS, Lee J, Lee KM, Yang SH, Choi S, Chung SYet al. (2003) Involvement of hydrogen peroxide in mistletoe lectin-II-induced apoptosis of myeloleukemic U937 cells. Life Sci.73, 1231-1243.
    • (2003) Life Sci. , vol.73 , pp. 1231-1243
    • Kim, M.S.1    Lee, J.2    Lee, K.M.3    Yang, S.H.4    Choi, S.5    Chung, S.Y.6
  • 53
    • 0032545386 scopus 로고    scopus 로고
    • Activation of mitochondria and release of mitochondrial apoptogenic factors by betulinic acid
    • Fulda S, Scaffidi C, Susin SA, Krammer PH, Kroemer G, Peter MEet al. (1998) Activation of mitochondria and release of mitochondrial apoptogenic factors by betulinic acid. J. Biol. Chem.273, 33942-33948.
    • (1998) J. Biol. Chem. , vol.273 , pp. 33942-33948
    • Fulda, S.1    Scaffidi, C.2    Susin, S.A.3    Krammer, P.H.4    Kroemer, G.5    Peter, M.E.6
  • 54
    • 0034641918 scopus 로고    scopus 로고
    • The biochemistry of apoptosis
    • Hengartner MO (2000) The biochemistry of apoptosis. Nature407, 770-776.
    • (2000) Nature , vol.407 , pp. 770-776
    • Hengartner, M.O.1
  • 55
    • 5644258322 scopus 로고    scopus 로고
    • c-Jun NH2-terminal kinase-mediated up-regulation of death receptor 5 contributes to induction of apoptosis by the novel synthetic triterpenoid methyl-2-cyano-3,12-dioxooleana-1, 9-dien-28-oate in human lung cancer cells
    • Zou W, Liu X, Yue P, Zhou Z, Sporn MB, Lotan Ret al. (2004) c-Jun NH2-terminal kinase-mediated up-regulation of death receptor 5 contributes to induction of apoptosis by the novel synthetic triterpenoid methyl-2-cyano-3, 12-dioxooleana-1, 9-dien-28-oate in human lung cancer cells. Cancer Res.64, 7570-7578.
    • (2004) Cancer Res. , vol.64 , pp. 7570-7578
    • Zou, W.1    Liu, X.2    Yue, P.3    Zhou, Z.4    Sporn, M.B.5    Lotan, R.6
  • 56
    • 67649921128 scopus 로고    scopus 로고
    • High sensitivity of ovarian cancer cells to the synthetic triterpenoid CDDO-Imidazolide
    • Petronelli A, Saulle E, Pasquini L, Petrucci E, Mariani G, Biffoni Met al. (2009) High sensitivity of ovarian cancer cells to the synthetic triterpenoid CDDO-Imidazolide. Cancer Lett.282, 214-228.
    • (2009) Cancer Lett. , vol.282 , pp. 214-228
    • Petronelli, A.1    Saulle, E.2    Pasquini, L.3    Petrucci, E.4    Mariani, G.5    Biffoni, M.6
  • 57
    • 41649085883 scopus 로고    scopus 로고
    • c-FLIP downregulation contributes to apoptosis induction by the novel synthetic triterpenoid methyl-2-cyano-3, 12-dioxooleana-1, 9-dien-28-oate (CDDO-Me) in human lung cancer cells
    • Zou W, Chen S, Liu X, Yue P, Sporn MB, Khuri FRet al. (2007) c-FLIP downregulation contributes to apoptosis induction by the novel synthetic triterpenoid methyl-2-cyano-3, 12-dioxooleana-1, 9-dien-28-oate (CDDO-Me) in human lung cancer cells. Cancer Biol. Ther.6, 1614-1620.
    • (2007) Cancer Biol. Ther. , vol.6 , pp. 1614-1620
    • Zou, W.1    Chen, S.2    Liu, X.3    Yue, P.4    Sporn, M.B.5    Khuri, F.R.6
  • 58
    • 33646771034 scopus 로고    scopus 로고
    • Depletion of intracellular glutathione contributes to JNK-mediated death receptor 5 upregulation and apoptosis induction by the novel synthetic triterpenoid methyl-2-cyano-3, 12-dioxooleana-1, 9-dien-28-oate (CDDO-Me)
    • Yue P, Zhou Z, Khuri FR, Sun SY (2006) Depletion of intracellular glutathione contributes to JNK-mediated death receptor 5 upregulation and apoptosis induction by the novel synthetic triterpenoid methyl-2-cyano-3, 12-dioxooleana-1, 9-dien-28-oate (CDDO-Me). Cancer Biol. Ther.5, 492-497.
    • (2006) Cancer Biol. Ther. , vol.5 , pp. 492-497
    • Yue, P.1    Zhou, Z.2    Khuri, F.R.3    Sun, S.Y.4
  • 59
    • 35449005931 scopus 로고    scopus 로고
    • Oleanolic acid induces apoptosis in human leukemia cells through caspase activation and poly(ADP-ribose) polymerase cleavage
    • Zhang P, Li H, Chen D, Ni J, Kang Y, Wang S (2007) Oleanolic acid induces apoptosis in human leukemia cells through caspase activation and poly(ADP-ribose) polymerase cleavage. Acta Biochim. Biophys. Sin. (Shanghai)39, 803-809.
    • (2007) Acta Biochim. Biophys. Sin. (Shanghai) , vol.39 , pp. 803-809
    • Zhang, P.1    Li, H.2    Chen, D.3    Ni, J.4    Kang, Y.5    Wang, S.6
  • 60
    • 4444281592 scopus 로고    scopus 로고
    • Induction of redox imbalance and apoptosis in multiple myeloma cells by the novel triterpenoid 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid
    • Ikeda T, Nakata Y, Kimura F, Sato K, Anderson K, Motoyoshi Ket al. (2004) Induction of redox imbalance and apoptosis in multiple myeloma cells by the novel triterpenoid 2-cyano-3, 12-dioxoolean-1, 9-dien-28-oic acid. Mol. Cancer Ther.3, 39-45.
    • (2004) Mol. Cancer Ther. , vol.3 , pp. 39-45
    • Ikeda, T.1    Nakata, Y.2    Kimura, F.3    Sato, K.4    Anderson, K.5    Motoyoshi, K.6
  • 61
    • 7444241538 scopus 로고    scopus 로고
    • The synthetic triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid induces caspase-dependent and -independent apoptosis in acute myelogenous leukemia
    • Konopleva M, Tsao T, Estrov Z, Lee RM, Wang RY, Jackson CEet al. (2004) The synthetic triterpenoid 2-cyano-3, 12-dioxooleana-1, 9-dien-28-oic acid induces caspase-dependent and -independent apoptosis in acute myelogenous leukemia. Cancer Res.64, 7927-7935.
    • (2004) Cancer Res. , vol.64 , pp. 7927-7935
    • Konopleva, M.1    Tsao, T.2    Estrov, Z.3    Lee, R.M.4    Wang, R.Y.5    Jackson, C.E.6
  • 62
    • 52049089207 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3beta regulates cell death induced by synthetic triterpenoids
    • Vene R, Larghero P, Arena G, Sporn MB, Albini A, Tosetti F (2008) Glycogen synthase kinase 3beta regulates cell death induced by synthetic triterpenoids. Cancer Res.68, 6987-6996.
    • (2008) Cancer Res. , vol.68 , pp. 6987-6996
    • Vene, R.1    Larghero, P.2    Arena, G.3    Sporn, M.B.4    Albini, A.5    Tosetti, F.6
  • 63
    • 49849093594 scopus 로고    scopus 로고
    • Inhibition of mitochondrial metabolism by methyl-2-cyano-3,12-dioxooleana-1,9-diene-28-oate induces apoptotic or autophagic cell death in chronic myeloid leukemia cells
    • Samudio I, Kurinna S, Ruvolo P, Korchin B, Kantarjian H, Beran Met al. (2008) Inhibition of mitochondrial metabolism by methyl-2-cyano-3, 12-dioxooleana-1, 9-diene-28-oate induces apoptotic or autophagic cell death in chronic myeloid leukemia cells. Mol. Cancer Ther.7, 1130-1139.
    • (2008) Mol. Cancer Ther. , vol.7 , pp. 1130-1139
    • Samudio, I.1    Kurinna, S.2    Ruvolo, P.3    Korchin, B.4    Kantarjian, H.5    Beran, M.6
  • 64
    • 0034069995 scopus 로고    scopus 로고
    • Modulation of mistletoe (Viscum album L.) lectins cytotoxicity by carbohydrates and serum glycoproteins
    • Frantz M, Jung ML, Ribereau-Gayon G, Anton R (2000) Modulation of mistletoe (Viscum album L.) lectins cytotoxicity by carbohydrates and serum glycoproteins. Arzneimittelforschung50, 471-478.
    • (2000) Arzneimittelforschung , vol.50 , pp. 471-478
    • Frantz, M.1    Jung, M.L.2    Ribereau-Gayon, G.3    Anton, R.4
  • 65
    • 0031009206 scopus 로고    scopus 로고
    • Modulation of cytotoxicity and enhancement of cytokine release induced by Viscum album L. extracts or mistletoe lectins
    • Ribereau-Gayon G, Jung ML, Frantz M, Anton R (1997) Modulation of cytotoxicity and enhancement of cytokine release induced by Viscum album L. extracts or mistletoe lectins. Anticancer Drugs8(Suppl. 1), S3-S8.
    • (1997) Anticancer Drugs , vol.8 , Issue.SUPPL. 1
    • Ribereau-Gayon, G.1    Jung, M.L.2    Frantz, M.3    Anton, R.4
  • 66
    • 12444337488 scopus 로고    scopus 로고
    • The novel synthetic triterpenoid, CDDO-imidazolide, inhibits inflammatory response and tumor growth in vivo
    • Place AE, Suh N, Williams CR, Risingsong R, Honda T, Honda Yet al. (2003) The novel synthetic triterpenoid, CDDO-imidazolide, inhibits inflammatory response and tumor growth in vivo. Clin. Cancer Res.9, 2798-2806.
    • (2003) Clin. Cancer Res. , vol.9 , pp. 2798-2806
    • Place, A.E.1    Suh, N.2    Williams, C.R.3    Risingsong, R.4    Honda, T.5    Honda, Y.6
  • 67
    • 76549112866 scopus 로고    scopus 로고
    • Triterpenoids CDDO-methyl ester or CDDO-ethyl amide and rexinoids LG100268 or NRX194204 for prevention and treatment of lung cancer in mice
    • Liby K, Risingsong R, Royce DB, Williams CR, Ma T, Yore MMet al. (2009) Triterpenoids CDDO-methyl ester or CDDO-ethyl amide and rexinoids LG100268 or NRX194204 for prevention and treatment of lung cancer in mice. Cancer Prev. Res. (Phila)2, 1050-1058.
    • (2009) Cancer Prev. Res. (Phila) , vol.2 , pp. 1050-1058
    • Liby, K.1    Risingsong, R.2    Royce, D.B.3    Williams, C.R.4    Ma, T.5    Yore, M.M.6
  • 68
    • 67650097012 scopus 로고    scopus 로고
    • Triterpenes augment the inhibitory effects of anticancer drugs on growth of human esophageal carcinoma cells in vitro and suppress experimental metastasis in vivo
    • Yamai H, Sawada N, Yoshida T, Seike J, Takizawa H, Kenzaki Ket al. (2009) Triterpenes augment the inhibitory effects of anticancer drugs on growth of human esophageal carcinoma cells in vitro and suppress experimental metastasis in vivo. Int. J. Cancer125, 952-960.
    • (2009) Int. J. Cancer , vol.125 , pp. 952-960
    • Yamai, H.1    Sawada, N.2    Yoshida, T.3    Seike, J.4    Takizawa, H.5    Kenzaki, K.6
  • 69
    • 79957484238 scopus 로고    scopus 로고
    • Oleanolic acid derivative Dex-OA has potent anti-tumor and anti-metastatic activity on osteosarcoma cells in vitro and in vivo
    • Hua Y, Zhang Z, Li J, Li Q, Hu S, Li Jet al. (2009) Oleanolic acid derivative Dex-OA has potent anti-tumor and anti-metastatic activity on osteosarcoma cells in vitro and in vivo. Invest. New Drugs29, 258-265.
    • (2009) Invest. New Drugs , vol.29 , pp. 258-265
    • Hua, Y.1    Zhang, Z.2    Li, J.3    Li, Q.4    Hu, S.5    Li, J.6


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