N-acetyl-L-cysteine modulates multiple signaling pathways to rescue male germ cells from apoptosis induced by chronic hCG administration to rats

Apoptosis

Volumn 17, Issue 6, 2012, Pages 551-565

  Maheshwari, Ankur ^a,b   Misro, M M ^a   Aggarwal, Archana ^a   Sharma, Rajnesh K ^b  

^a NATIONAL INSTITUTE OF HEALTH AND FAMILY WELFARE   (India)

^b KURUKSHETRA UNIVERSITY   (India)

Author keywords

Apoptosis; Chronic hCG treatment; Germ cell survival; NAC co treatment; Oxidative stress; Testis

Indexed keywords

ACETYLCYSTEINE; CASPASE 3; CASPASE 8; CASPASE 9; CHORIONIC GONADOTROPIN; FAS ANTIGEN; FAS LIGAND; GLUTATHIONE; HYDROGEN PEROXIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN C JUN; PROTEIN KINASE B; STRESS ACTIVATED PROTEIN KINASE; TESTOSTERONE;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL PROTECTION; CELL SURVIVAL; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFICACY; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME REGULATION; GERM CELL; HISTOLOGY; INTRACELLULAR SIGNALING; INTRACELLULAR SPACE; LIPID PEROXIDATION; MALE; NICK END LABELING; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; RAT; SPERMATOGENESIS; TESTIS; TESTIS WEIGHT; TESTOSTERONE BLOOD LEVEL; UPREGULATION;

ACETYLCYSTEINE; ANIMALS; APOPTOSIS; CHORIONIC GONADOTROPIN; HUMANS; MALE; RATS; SIGNAL TRANSDUCTION; SPERMATOGENESIS; SPERMATOZOA; TESTIS;

METAZOA; RATTUS;

EID: 84862504568     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-012-0703-8     Document Type: Article

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