메뉴 건너뛰기




Volumn 59, Issue 5, 1998, Pages 1037-1046

Relative impact of oxidative stress on the functional competence and genomic integrity of human spermatozoa

Author keywords

[No Author keywords available]

Indexed keywords

CELL DNA; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;

EID: 0031768343     PISSN: 00063363     EISSN: None     Source Type: Journal    
DOI: 10.1095/biolreprod59.5.1037     Document Type: Article
Times cited : (676)

References (58)
  • 1
    • 0001387519 scopus 로고
    • The role of oxygen in the metabolism and motility of human spermatozoa
    • MacLeod J. The role of oxygen in the metabolism and motility of human spermatozoa. Am J Physiol 1943; 138:512-518.
    • (1943) Am J Physiol , vol.138 , pp. 512-518
    • MacLeod, J.1
  • 2
    • 0024267840 scopus 로고
    • Significance of reactive oxygen species and anti-oxidants in defining the efficacy of sperm preparation techniques
    • Aitken RJ, Clarkson JS. Significance of reactive oxygen species and anti-oxidants in defining the efficacy of sperm preparation techniques. J Androl 1988; 9:367-376.
    • (1988) J Androl , vol.9 , pp. 367-376
    • Aitken, R.J.1    Clarkson, J.S.2
  • 3
    • 0023412036 scopus 로고
    • Spontaneous lipid peroxidation and production of hydrogen peroxide and superoxide in human spermatozoa
    • Alvarez JG, Touchstone JC, Blasco L, Storey BT. Spontaneous lipid peroxidation and production of hydrogen peroxide and superoxide in human spermatozoa. J Androl 1987; 8:338-348.
    • (1987) J Androl , vol.8 , pp. 338-348
    • Alvarez, J.G.1    Touchstone, J.C.2    Blasco, L.3    Storey, B.T.4
  • 4
    • 0026540891 scopus 로고
    • Formation of reactive oxygen species in spermatozoa of infertile patients
    • Iwasaki A, Gagnon C. Formation of reactive oxygen species in spermatozoa of infertile patients. Fertil Steril 1992; 57:409-416.
    • (1992) Fertil Steril , vol.57 , pp. 409-416
    • Iwasaki, A.1    Gagnon, C.2
  • 5
    • 0024365662 scopus 로고
    • Analysis of the relationship between defective sperm function and the generation of reactive oxygen species in cases of oligozoospermia
    • Aitken RJ, Clarkson JS, Hargreave TB, Irvine DS, Wu FCW. Analysis of the relationship between defective sperm function and the generation of reactive oxygen species in cases of oligozoospermia. J Androl 1989; 10:214-220.
    • (1989) J Androl , vol.10 , pp. 214-220
    • Aitken, R.J.1    Clarkson, J.S.2    Hargreave, T.B.3    Irvine, D.S.4    Wu, F.C.W.5
  • 6
    • 0026533564 scopus 로고
    • Differential contribution of leucocytes and spermatozoa to the high levels of reactive oxygen species recorded in the ejaculates of oligozoospermic patients
    • Aitken RJ, Buckingham D, West K, Wu FC, Zikopoulos K, Richardson DW. Differential contribution of leucocytes and spermatozoa to the high levels of reactive oxygen species recorded in the ejaculates of oligozoospermic patients. J Reprod Fertil 1992; 94:451-462.
    • (1992) J Reprod Fertil , vol.94 , pp. 451-462
    • Aitken, R.J.1    Buckingham, D.2    West, K.3    Wu, F.C.4    Zikopoulos, K.5    Richardson, D.W.6
  • 7
    • 0030464440 scopus 로고    scopus 로고
    • Role of reactive oxygen species in male infertility
    • Sharma RK, Agarwal A. Role of reactive oxygen species in male infertility. Urology 1996; 48:835-850.
    • (1996) Urology , vol.48 , pp. 835-850
    • Sharma, R.K.1    Agarwal, A.2
  • 8
    • 0027952740 scopus 로고
    • Correlation between the rate of lipid peroxidation and cellular maturity as measured by creatine kinase activity in human spermatozoa
    • Huszar G, Vigue L. Correlation between the rate of lipid peroxidation and cellular maturity as measured by creatine kinase activity in human spermatozoa. J Androl 1994; 15:71-77.
    • (1994) J Androl , vol.15 , pp. 71-77
    • Huszar, G.1    Vigue, L.2
  • 9
    • 0029896377 scopus 로고    scopus 로고
    • Development of an image analysis system to monitor the retention of residual cytoplasm by human spermatozoa: Correlation with biochemical markers of the cytoplasmic space, oxidative stress and sperm function
    • Gomez E, Buckingham D, Brindle J, Lanzafame F, Irvine DS, Aitken RJ. Development of an image analysis system to monitor the retention of residual cytoplasm by human spermatozoa: correlation with biochemical markers of the cytoplasmic space, oxidative stress and sperm function. J Androl 1996; 17:276-287.
    • (1996) J Androl , vol.17 , pp. 276-287
    • Gomez, E.1    Buckingham, D.2    Brindle, J.3    Lanzafame, F.4    Irvine, D.S.5    Aitken, R.J.6
  • 10
    • 0028042392 scopus 로고
    • Relationships between biochemical markers for residual sperm cytoplasm, reactive oxygen species generation, and the presence of leukocytes and precursor germ cells in human sperm suspensions
    • Aitken RJ, Krausz C, Buckingham D. Relationships between biochemical markers for residual sperm cytoplasm, reactive oxygen species generation, and the presence of leukocytes and precursor germ cells in human sperm suspensions. Mol Reprod Dev 1994; 39:268-279.
    • (1994) Mol Reprod Dev , vol.39 , pp. 268-279
    • Aitken, R.J.1    Krausz, C.2    Buckingham, D.3
  • 11
    • 0031007755 scopus 로고    scopus 로고
    • Reactive oxygen species generation by human spermatozoa is induced by exogenous NADPH and inhibited by the flavoprotein inhibitors diphenylene iodonium and quinacrine
    • Aitken RJ, Fisher HM, Fulton N, Gomez E, Knox W, Lewis B, Irvine S. Reactive oxygen species generation by human spermatozoa is induced by exogenous NADPH and inhibited by the flavoprotein inhibitors diphenylene iodonium and quinacrine. Mol Reprod Dev 1997; 47:468-482.
    • (1997) Mol Reprod Dev , vol.47 , pp. 468-482
    • Aitken, R.J.1    Fisher, H.M.2    Fulton, N.3    Gomez, E.4    Knox, W.5    Lewis, B.6    Irvine, S.7
  • 12
    • 0029046131 scopus 로고
    • Redox regulation of tyrosine phosphorylation in human spermatozoa and its role in the control of human sperm function
    • Aitken RJ, Paterson M, Fisher H, Buckingham DW, van Duin M. Redox regulation of tyrosine phosphorylation in human spermatozoa and its role in the control of human sperm function. J Cell Sci 1995; 108:2017-2025.
    • (1995) J Cell Sci , vol.108 , pp. 2017-2025
    • Aitken, R.J.1    Paterson, M.2    Fisher, H.3    Buckingham, D.W.4    Van Duin, M.5
  • 13
    • 0029919631 scopus 로고    scopus 로고
    • The extragenomic action of progesterone on human spermatozoa is influenced by redox regulated changes in tyrosine phosphorylation during capacitation
    • Aitken RJ, Buckingham DW, Harkiss D, Paterson M, Fisher H, Irvine DS. The extragenomic action of progesterone on human spermatozoa is influenced by redox regulated changes in tyrosine phosphorylation during capacitation. Mol Cell Endocrinol 1996; 117:83-93.
    • (1996) Mol Cell Endocrinol , vol.117 , pp. 83-93
    • Aitken, R.J.1    Buckingham, D.W.2    Harkiss, D.3    Paterson, M.4    Fisher, H.5    Irvine, D.S.6
  • 14
    • 0031036435 scopus 로고    scopus 로고
    • Regulation of protein-tyrosine phosphorylation and human sperm capacitation by reactive oxygen derivatives
    • Leclerc P, de Lamirande E, Gagnon C. Regulation of protein-tyrosine phosphorylation and human sperm capacitation by reactive oxygen derivatives. Free Radical Biol Med 1997; 22:643-656.
    • (1997) Free Radical Biol Med , vol.22 , pp. 643-656
    • Leclerc, P.1    De Lamirande, E.2    Gagnon, C.3
  • 15
    • 0027207259 scopus 로고
    • Use of a xanthine oxidase oxidant generating system to investigate the cytotoxic effects of reactive oxygen species on human spermatozoa
    • Aitken RJ, Buckingham D, Harkiss D. Use of a xanthine oxidase oxidant generating system to investigate the cytotoxic effects of reactive oxygen species on human spermatozoa. J Reprod Fertil 1992; 97:441-450.
    • (1992) J Reprod Fertil , vol.97 , pp. 441-450
    • Aitken, R.J.1    Buckingham, D.2    Harkiss, D.3
  • 16
    • 0026688587 scopus 로고
    • Reactive oxygen species and human spermatozoa. I. Effects on the motility of intact spermatozoa and on sperm axonemes
    • De Lamirande E, Gagnon C. Reactive oxygen species and human spermatozoa. I. Effects on the motility of intact spermatozoa and on sperm axonemes. J Androl 1992; 13:368-378.
    • (1992) J Androl , vol.13 , pp. 368-378
    • De Lamirande, E.1    Gagnon, C.2
  • 17
    • 0028965632 scopus 로고
    • Reactive oxygen species, lipid peroxidation and enzymatic defence systems in human spermatozoa
    • Griveau JF, Dumont E, Renard P, Callegari JP, Le Lannou D. Reactive oxygen species, lipid peroxidation and enzymatic defence systems in human spermatozoa. J Reprod Fertil 1995; 103:17-26.
    • (1995) J Reprod Fertil , vol.103 , pp. 17-26
    • Griveau, J.F.1    Dumont, E.2    Renard, P.3    Callegari, J.P.4    Le Lannou, D.5
  • 18
    • 0018341406 scopus 로고
    • Peroxidative breakdown of phospholipids in human spermatozoa: Spermicidal effects of fatty acid peroxides and protective action of seminal plasma
    • Jones R, Mann T, Sherins RJ. Peroxidative breakdown of phospholipids in human spermatozoa: spermicidal effects of fatty acid peroxides and protective action of seminal plasma. Fertil Steril 1979; 31:531-537.
    • (1979) Fertil Steril , vol.31 , pp. 531-537
    • Jones, R.1    Mann, T.2    Sherins, R.J.3
  • 19
    • 0031090459 scopus 로고    scopus 로고
    • Biochemistry of the induction and prevention of lipoperoxidative damage in human spermatozoa
    • Storey BT. Biochemistry of the induction and prevention of lipoperoxidative damage in human spermatozoa. Mol Hum Reprod 1997; 3: 203-214.
    • (1997) Mol Hum Reprod , vol.3 , pp. 203-214
    • Storey, B.T.1
  • 20
    • 0028409709 scopus 로고
    • Reactive oxygen species generation and human spermatozoa: The balance of benefit and risk
    • Aitken RJ, Fisher H. Reactive oxygen species generation and human spermatozoa: the balance of benefit and risk. Bioessays 1994; 16:259-267.
    • (1994) Bioessays , vol.16 , pp. 259-267
    • Aitken, R.J.1    Fisher, H.2
  • 21
    • 0028891932 scopus 로고
    • Differential incorporation of fatty acids into and peroxidative loss of fatty acids from phospholipids of human spermatozoa
    • Alvarez JG, Storey BT. Differential incorporation of fatty acids into and peroxidative loss of fatty acids from phospholipids of human spermatozoa. Mol Reprod Dev 1995; 42:334-336.
    • (1995) Mol Reprod Dev , vol.42 , pp. 334-336
    • Alvarez, J.G.1    Storey, B.T.2
  • 22
    • 0027992084 scopus 로고
    • Stimulation of oxidant generation by human sperm suspensions using phorbol esters and formyl peptides: Relationship with motility and fertilization in vitro
    • Krausz C, Mills C, Rogers S, Tan SL, Aitken RJ. Stimulation of oxidant generation by human sperm suspensions using phorbol esters and formyl peptides: relationship with motility and fertilization in vitro. Fertil Steril 1994; 62:599-605.
    • (1994) Fertil Steril , vol.62 , pp. 599-605
    • Krausz, C.1    Mills, C.2    Rogers, S.3    Tan, S.L.4    Aitken, R.J.5
  • 23
    • 0029072124 scopus 로고
    • Predicting the fertilizing potential of human sperm suspensions in vitro: Importance of sperm morphology and leukocyte contamination
    • Sukcharoen N, Keith J, Irvine DS, Aitken RJ. Predicting the fertilizing potential of human sperm suspensions in vitro: importance of sperm morphology and leukocyte contamination. Fertil Steril 1995; 63:1293-1300.
    • (1995) Fertil Steril , vol.63 , pp. 1293-1300
    • Sukcharoen, N.1    Keith, J.2    Irvine, D.S.3    Aitken, R.J.4
  • 24
    • 0030202411 scopus 로고    scopus 로고
    • A comparison of baseline and induced DNA damage in human spermatozoa from fertile and infertile men using a modified comet assay
    • Hughes CM, Lewis SEM, McKelvey-Martin VJ, Thompson W. A comparison of baseline and induced DNA damage in human spermatozoa from fertile and infertile men using a modified comet assay. Mol Hum Reprod 1996; 2:613-620.
    • (1996) Mol Hum Reprod , vol.2 , pp. 613-620
    • Hughes, C.M.1    Lewis, S.E.M.2    McKelvey-Martin, V.J.3    Thompson, W.4
  • 25
    • 0343907222 scopus 로고    scopus 로고
    • Increased oxidative deoxyribonucleic acid damage in the spermatozoa of infertile male patients
    • Kodoma H, Yamaguchi R, Fukuda J, Kasai H, Tanaka T. Increased oxidative deoxyribonucleic acid damage in the spermatozoa of infertile male patients. Fertil Steril 1997; 68:519-524.
    • (1997) Fertil Steril , vol.68 , pp. 519-524
    • Kodoma, H.1    Yamaguchi, R.2    Fukuda, J.3    Kasai, H.4    Tanaka, T.5
  • 26
    • 0031045420 scopus 로고    scopus 로고
    • Detection of deoxyribonucleic acid fragmentation in human sperm: Correlation with fertilization in vitro
    • Sun JG, Jurisicova A, Casper RF. Detection of deoxyribonucleic acid fragmentation in human sperm: correlation with fertilization in vitro. Biol Reprod 1997; 56:602-607.
    • (1997) Biol Reprod , vol.56 , pp. 602-607
    • Sun, J.G.1    Jurisicova, A.2    Casper, R.F.3
  • 27
    • 0031563793 scopus 로고    scopus 로고
    • Susceptibility of human sperm to in situ DNA denaturation is strongly correlated with DNA strand breaks identified by single-cell electrophoresis
    • Aravindan GR, Bjordahl J, Jost LK, Evenson DP. Susceptibility of human sperm to in situ DNA denaturation is strongly correlated with DNA strand breaks identified by single-cell electrophoresis. Exp Cell Res 1997; 236:231-237.
    • (1997) Exp Cell Res , vol.236 , pp. 231-237
    • Aravindan, G.R.1    Bjordahl, J.2    Jost, L.K.3    Evenson, D.P.4
  • 28
    • 0019296108 scopus 로고
    • Relation of mammalian sperm chromatin heterogeneity to fertility
    • Evenson DP, Darzynkiewicz Z, Malamed MR. Relation of mammalian sperm chromatin heterogeneity to fertility. Science 1980; 240:1131-1133.
    • (1980) Science , vol.240 , pp. 1131-1133
    • Evenson, D.P.1    Darzynkiewicz, Z.2    Malamed, M.R.3
  • 29
    • 0024427034 scopus 로고
    • Generation of reactive oxygen species, lipid peroxidation and human sperm function
    • Aitken RJ, Clarkson JS, Fishel S. Generation of reactive oxygen species, lipid peroxidation and human sperm function. Biol Reprod 1989; 41:183-187.
    • (1989) Biol Reprod , vol.41 , pp. 183-187
    • Aitken, R.J.1    Clarkson, J.S.2    Fishel, S.3
  • 30
    • 0029917272 scopus 로고    scopus 로고
    • Smoking and low antioxidant levels increase oxidative damage to sperm DNA
    • Fraga CG, Motchnik PA, Wyrobek AJ, Rempel DM, Ames BN. Smoking and low antioxidant levels increase oxidative damage to sperm DNA. Mutat Res 1996; 351:199-203.
    • (1996) Mutat Res , vol.351 , pp. 199-203
    • Fraga, C.G.1    Motchnik, P.A.2    Wyrobek, A.J.3    Rempel, D.M.4    Ames, B.N.5
  • 32
    • 0017140969 scopus 로고
    • The use of zona free animal ova as a test system for the assessment of the fertilizing capacity of human spermatozoa
    • Yanagimachi R, Yanagimachi H, Rogers BJ. The use of zona free animal ova as a test system for the assessment of the fertilizing capacity of human spermatozoa. Biol Reprod 1976; 15:471-476.
    • (1976) Biol Reprod , vol.15 , pp. 471-476
    • Yanagimachi, R.1    Yanagimachi, H.2    Rogers, B.J.3
  • 34
    • 0028856250 scopus 로고
    • Definition of the optimal criteria for identifying hyperactivated spermatozoa at 25 Hz using in vitro fertilization as a functional end-point
    • Sukcharoen N, Keith J, Irvine DS, Aitken RJ. Definition of the optimal criteria for identifying hyperactivated spermatozoa at 25 Hz using in vitro fertilization as a functional end-point. Hum Reprod 1995; 10: 2928-2937.
    • (1995) Hum Reprod , vol.10 , pp. 2928-2937
    • Sukcharoen, N.1    Keith, J.2    Irvine, D.S.3    Aitken, R.J.4
  • 37
    • 0002597916 scopus 로고    scopus 로고
    • The extragenomic action of progesterone on human spermatozoa
    • Aitken RJ. The extragenomic action of progesterone on human spermatozoa. Hum Reprod 1997; 12:38-42.
    • (1997) Hum Reprod , vol.12 , pp. 38-42
    • Aitken, R.J.1
  • 38
    • 0031090408 scopus 로고    scopus 로고
    • Molecular mechanisms regulating human sperm function
    • Aitken RJ. Molecular mechanisms regulating human sperm function. Mol Hum Reprod 1997; 3:169-173.
    • (1997) Mol Hum Reprod , vol.3 , pp. 169-173
    • Aitken, R.J.1
  • 39
    • 0030820190 scopus 로고    scopus 로고
    • Reactive oxygen species and human spermatozoa: Physiology and pathology
    • Griveau JF, Le Lannou D. Reactive oxygen species and human spermatozoa: physiology and pathology. Int J Androl 1997; 20:61-69.
    • (1997) Int J Androl , vol.20 , pp. 61-69
    • Griveau, J.F.1    Le Lannou, D.2
  • 40
    • 0027396562 scopus 로고
    • Human sperm hyperactivation as part of an oxidative process
    • de Lamirande E, Gagnon C. Human sperm hyperactivation as part of an oxidative process. Free Radical Biol Med 1993; 314:157-166.
    • (1993) Free Radical Biol Med , vol.314 , pp. 157-166
    • De Lamirande, E.1    Gagnon, C.2
  • 41
    • 0031091039 scopus 로고    scopus 로고
    • Capacitation as a regulatory event that primes spermatozoa for the acrosome reaction and fertilization
    • de Lamirande E, Leclerc P, Gagnon C. Capacitation as a regulatory event that primes spermatozoa for the acrosome reaction and fertilization. Mol Hum Reprod 1997; 3:175-194.
    • (1997) Mol Hum Reprod , vol.3 , pp. 175-194
    • De Lamirande, E.1    Leclerc, P.2    Gagnon, C.3
  • 42
    • 0025095406 scopus 로고
    • Progesterone and 17α-hydroxy-progesterone. Novel stimulators of calcium influx in human spermatozoa
    • Blackmore PF, Beebe SJ, Danforth DR, Alexander N. Progesterone and 17α-hydroxy-progesterone. Novel stimulators of calcium influx in human spermatozoa. J Biol Chem 1990; 265:1376-1380.
    • (1990) J Biol Chem , vol.265 , pp. 1376-1380
    • Blackmore, P.F.1    Beebe, S.J.2    Danforth, D.R.3    Alexander, N.4
  • 44
    • 0031890532 scopus 로고    scopus 로고
    • A novel signal transduction cascade in capacitating human spermatozoa characterised by a redox regulated, cAMP-mediated induction of tyrosine phosphorylation
    • Aitken RJ, Harkiss D, Knox W, Paterson M, Irvine DS. A novel signal transduction cascade in capacitating human spermatozoa characterised by a redox regulated, cAMP-mediated induction of tyrosine phosphorylation. J Cell Sci 1998; 111:645-656.
    • (1998) J Cell Sci , vol.111 , pp. 645-656
    • Aitken, R.J.1    Harkiss, D.2    Knox, W.3    Paterson, M.4    Irvine, D.S.5
  • 45
    • 0026032205 scopus 로고
    • Hydrogen peroxide is involved in hamster sperm capacitation in vitro
    • Bize I, Santander G, Cabello P, Driscoll D, Sharpe C. Hydrogen peroxide is involved in hamster sperm capacitation in vitro. Biol Reprod 1991; 44:389-403.
    • (1991) Biol Reprod , vol.44 , pp. 389-403
    • Bize, I.1    Santander, G.2    Cabello, P.3    Driscoll, D.4    Sharpe, C.5
  • 46
    • 0028957362 scopus 로고
    • Capacitation of mouse spermatozoa, 1. Correlation between the capacitation state and protein tyrosine phosphorylation
    • Visconti PE, Bailey JL, Moore GD, Pan D, Olds-Clarke P, Kopf GS. Capacitation of mouse spermatozoa, 1. Correlation between the capacitation state and protein tyrosine phosphorylation. Development 1995; 121:1129-1137.
    • (1995) Development , vol.121 , pp. 1129-1137
    • Visconti, P.E.1    Bailey, J.L.2    Moore, G.D.3    Pan, D.4    Olds-Clarke, P.5    Kopf, G.S.6
  • 47
    • 0030667302 scopus 로고    scopus 로고
    • Distribution and possible novel role of phospholipid hydroperoxide glutathione peroxidase in rat epididymal spermatozoa
    • Godeas C, Tramer F, Micali F, Soranzo M, Sandri G, Panfili E. Distribution and possible novel role of phospholipid hydroperoxide glutathione peroxidase in rat epididymal spermatozoa. Biol Reprod 1997; 57:1502-1508.
    • (1997) Biol Reprod , vol.57 , pp. 1502-1508
    • Godeas, C.1    Tramer, F.2    Micali, F.3    Soranzo, M.4    Sandri, G.5    Panfili, E.6
  • 48
    • 0027430736 scopus 로고
    • Effect of deoxyribonucleic acid protamination on fluorochrome staining and in situ nick-translation of murine and human mature spermatozoa
    • Bianchi PG, Manicardi GC, Bizzaro D, Bianchi U, Sakkas D. Effect of deoxyribonucleic acid protamination on fluorochrome staining and in situ nick-translation of murine and human mature spermatozoa. Biol Reprod 1993; 49:1083-1088.
    • (1993) Biol Reprod , vol.49 , pp. 1083-1088
    • Bianchi, P.G.1    Manicardi, G.C.2    Bizzaro, D.3    Bianchi, U.4    Sakkas, D.5
  • 49
    • 0031969435 scopus 로고    scopus 로고
    • DNA strand breaks in ejaculated human spermatozoa: Comparison of susceptibility to the nick translation and terminal transferase assays
    • Manicardi GC, Tombacco A, Bizzaro D, Bianchi U, Bianchi PG, Sakkas D. DNA strand breaks in ejaculated human spermatozoa: comparison of susceptibility to the nick translation and terminal transferase assays. Histochem J 1998; 30:33-39.
    • (1998) Histochem J , vol.30 , pp. 33-39
    • Manicardi, G.C.1    Tombacco, A.2    Bizzaro, D.3    Bianchi, U.4    Bianchi, P.G.5    Sakkas, D.6
  • 50
    • 0031127073 scopus 로고    scopus 로고
    • Comparative analysis of the ability of precursor germ cells and epididymal spermatozoa to generate reactive oxygen metabolites
    • Fisher HM, Aitken RJ. Comparative analysis of the ability of precursor germ cells and epididymal spermatozoa to generate reactive oxygen metabolites. J Exp Zool 1997; 277:390-400.
    • (1997) J Exp Zool , vol.277 , pp. 390-400
    • Fisher, H.M.1    Aitken, R.J.2
  • 51
    • 0032227033 scopus 로고    scopus 로고
    • Maturation of redox regulatory mechanisms in the epididymis
    • in press
    • Aitken RJ, Vernet P. Maturation of redox regulatory mechanisms in the epididymis. J Reprod Fertil Suppl 1998; 53:(in press).
    • (1998) J Reprod Fertil Suppl , vol.53
    • Aitken, R.J.1    Vernet, P.2
  • 53
    • 0024337024 scopus 로고
    • Role of glutathione peroxidase in protecting mammalian spermatozoa from loss of motility caused by spontaneous lipid peroxidation
    • Alvarez JG, Storey BT. Role of glutathione peroxidase in protecting mammalian spermatozoa from loss of motility caused by spontaneous lipid peroxidation. Gamete Res 1989: 23:77-90.
    • (1989) Gamete Res , vol.23 , pp. 77-90
    • Alvarez, J.G.1    Storey, B.T.2
  • 57
    • 0031822760 scopus 로고    scopus 로고
    • Oxidative damage to DNA in human spermatozoa does not preclude pronucleus formation at ICSI
    • in press
    • Twigg J, Irvine DS, Aitken RJ. Oxidative damage to DNA in human spermatozoa does not preclude pronucleus formation at ICSI. Hum Reprod 1998; (in press).
    • (1998) Hum Reprod
    • Twigg, J.1    Irvine, D.S.2    Aitken, R.J.3
  • 58
    • 0026533564 scopus 로고
    • Differential contribution of leucocytes and spermatozoa to the high levels of reactive oxygen species recorded in the ejaculates of oligozoospermic patients
    • Aitken RJ, Buckingham D, West K, Wu FC, Zikopoulos K, Richardson DW. Differential contribution of leucocytes and spermatozoa to the high levels of reactive oxygen species recorded in the ejaculates of oligozoospermic patients. J Reprod Fertil 1992; 94:451-462.
    • (1992) J Reprod Fertil , vol.94 , pp. 451-462
    • Aitken, R.J.1    Buckingham, D.2    West, K.3    Wu, F.C.4    Zikopoulos, K.5    Richardson, D.W.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.