Pathways involved in testicular germ cell apoptosis in immature rats after FSH suppression

Journal of Endocrinology

Volumn 197, Issue 1, 2008, Pages 35-43

  Ruwanpura, Saleela M ^a,b   McLachlan, Robert I ^a,b   Stanton, Peter G ^a   Loveland, Kate L ^c   Meachem, Sarah J ^a  

^a HUDSON INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b MONASH UNIVERSITY   (Australia)

^c Australian Government Australian Research Council   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 8; CASPASE 9; FOLLITROPIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL COUNT; CELL SURVIVAL; CONTROLLED STUDY; GENE EXPRESSION; GENETIC TRANSCRIPTION; GERM CELL; IMMATURITY; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; IN VIVO STUDY; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SPERMATOCYTE; SPERMATOGENESIS; SPERMATOGONIUM; STEREOLOGY;

ANIMALS; APOPTOSIS; CASPASE 8; CASPASE 9; FOLLICLE STIMULATING HORMONE; IN SITU NICK-END LABELING; MALE; RATS; RATS, SPRAGUE-DAWLEY; SPERMATOCYTES;

EID: 42449088583     PISSN: 00220795     EISSN: 14796805     Source Type: Journal    
DOI: 10.1677/JOE-07-0637     Document Type: Article

References (33)

1. Adams JM & Cory S 1998 The Bcl-2 protein family: arbiters of cell survival. Science 281 1322-1326.
2. Boitani C, Stefanini M, Fragale A & Morena AR 1995 Activin stimulates Sertoli cell proliferation in a defined period of rat testis development. Endocrinology 136 5438-5444.
3. Chausiaux OE, Abel MH, Baxter FO, Khaled WT, Ellis PJ, Charlton HM & Affara NA 2008 Hypogonadal mouse, a model to study the efects ofthe endogenous lack of gonadotropins on apoptosis. Biolqqy of Reproduction 78 77-90.
4. Codelia VA, Cisternas P & Moreno RD 2007 Relevance of caspase activity during apoptosis in pubertal rat spermatogenesis. Molecular Reproduction and Development In press.
5. D'Alessio A, Riccioli A, Lauretti P, Padula F, Muciaccia B, De Cesaris P, Filippini A, Nagata S & Ziparo E 2001 Testiculor FasL is expressed by sperm cells. PNAS 98 3316-3321.
6. Erkkila K, Pentikainen V, Wilostrom M, Parvinen M & Dunkel L 1999 Partial oxygen pressure and mitochondrial permeability transition affect germ cell apoptosis in the human testis. Journal of Clinical Endocrinology and Metabolism 84 4253-4259.
7. Green DR 2000 Apoptotic pathways: paper wraps stone blunts scissors. Cell 102 l-4.
8. Hengartner MO 2000 The biochemistry of apoptosis. Nature 407 770-776.
9. Huang W, Dobberfuhl A, Filippopoulos T, Ingelsson M, Fileta JB, Poulin AR & Grosskreutz CL 2005 Transcriptional up regulation and activation of initiating caspases in experimental glaucoma. American Journal of Pathologgy 167 673-681.
10. Knudson CM, Tung KS, Tourtellotte WG, Brown GA & Korsmeyer SJ 1995 Bax-deficient mice with lymphoid hyperplasia and male germ cell death. Science 270 96-99.
11. Koji T 2001 Male germ cell death in mouse testes: possible involvement of Fas and Fas ligand. Medical Electron Microscopy 34 213-222.
12. Lee J, Richburg JH, Younkin SC & Boekelheide K 1997 The Fas system is a key regulator of germ cell apoptosis in the testis. Endocrinology 138 2081-2088.
13. Lin Y, Kokontis J, Tang F, Godfrey B, Liao S, Lin A, Chen Y & Xiang J 2006 Androgen and its receptor promote Bax-mediated apoptosas. Molecular and Cellular Biology 26 1908-1916.
14. Lizama C, Alfaro I, Reyes JG & Moreno RD 2007 Up-regulation of CD95 (Apo-1/Fas) is associated with spermatocyte ipoptosis during the first round of spermatogenesis in the rat. Apoptosis 12 499-512.
15. Meachem SJ, Wreford NG, Stanton PG, Robertson DM & McLachlan RI 1998 Follicle-stimulating hormone is required for the initial phase of spermatogenic restoration in adult rats following gonadotropin suppression. Journal of Andrology 19 725-735.
16. Meachem SJ, Ruwanpura SM, Ziolkowski J, Ague JM, Skinner MK & Loveland KL 2005 Developmentally distinct in vivo effects of FSH on proliferation and apoplosis during testis maturation. Journal of Endocrinology 186 429-446.
17. Moreno RD, Lizama C, Urzua N, Vergara SP & Reyes JG 2006 Caspase activation throughout the first wave of spermatogenesis in the rat. Cell and Tissue Research 325 533-540.
18. Nagata S & Golstein P 1995 The Fas death factor. Science 267 1449-1456.
19. Nandi S, Banerjee PP & Zirkin BR 1999 Germ cell apoptosis in the testes of Sprague Dawley rats following testosterone withdrawal by ethane 1,2-dimethanesulfonate administration relationship to Fas? Biology of Reproduction 61 70-75.
20. Orth JM 1984 The role of follicle-stimulating hormone in controlling Sertoli cell proliferation in testes of fetal rats. Endocrinology 115 1248-1255.
21. Orth JM, Gunsalus GL & Lamperti AA 1988 Evidence from Sertoli cell-depleted rats indicates that spermatid number in adults depends on numbers of Sertoli cells produced during perinatal development. Endocrinology 122 787-794.
22. Orth JM, McGuinness MP, Qiu J, Jester WF, Jr & Li LH 1998 Use of in vitro systems to study male germ cell development in neonatal rats. Theriogenology 49 431-439.
23. Rodriguez I, Ody C, Araki K, Garcia I & Vassalli P 1997 An early and massive wave of germinal cell apoptosis is required for the development of functional spermatogenesis. EMBO Journal 16 2262-2270.
24. de Rooij DG 1998 Stem cells in the testis. International Journal of Experimental Pathology 79 67-80.
25. Russell LD, Ettlin RA, Sinha-Hikim AP & Clegg ED 1990 In Histological and Histopathological Evaluation of the Testis, Ed. LD Russell. Clearwater, Florida: Cache River Press.
26. Ruwanpura SM, McLachlan RI, Stanton PG & Meachem SJ 2007 FSH affects spermatogonial survival by regulating the intrinsic pathway in adult rats. Biology of Reproduction In press.
27. Ruwanpura SM, McLachlan RI, Matthiesson KL & Meachem SJ 2008 Gonadotropins regulate germ cell survival, not proliferation, in normal adult men. Human Reproduction 23 403-411.
28. Said TM, Paasch U, Glander HJ & Agarwal A 2004 Role of caspases in male infertility. Human Reproduction Update 10 39-51.
29. Scaffidi C, Schmitz I, Zha J, Korsmeyer SJ, Krammer PH & Peter ME 1999 Differential modulation of apoptosis sensitivity in CD95 type I and type II cells. Journal of Biological Chemistry 274 22532-22538.
30. Sinha-Hikim AP, Lue Y, Diaz-Romero M, Yen PH, Wang C & Swerdloff RS 2003a Deciphering the pathways of germ cell apoptosis in the testis. Journal of Steroid Biochemistry and Molecular Biology 85 175-182.
31. Sinha-Hikim AP, Lue Y, Yamamoto CM, Vera Y, Rodriguez S, Yen PH, Soeng K, Wang C & Swerdloff RS 2003b Key apoptotic pathways for heat-induced programmed germ cell death in the testis. Endocrinology 144 3167-3175.
32. Tolba RH, Schildberg FA, Schnurr C, Glatzel U, Decker D & Minor T 2006 Reduced liver apoptosis after venous systemic oxygen persufflation in non-heart-beating donors. Journal of Investigative Surgery 19 219-227.
33. Woolveridge I, de Boer-Brouwer M, Taylor MF, Teerds KJ, Wu FC & Morris ID 1999 Apoptosis in the rat spermatogenic epithelium following androgen withdrawal: changes in apoptosis-related genes. Biology of Reproduction 60 461-470.