The p53 protein influences the sensitivity of testicular germ cells to mono-(2-ethylhexyl) phthalate-induced apoptosis by increasing the membrane levels of Fas and DR5 and decreasing the intracellular amount of c-FLIP

Biology of Reproduction

Volumn 72, Issue 1, 2005, Pages 206-213

  Chandrasekaran, Yamini ^a   Richburg, John H ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

Author keywords

Apoptosis; Sertoli cells; Signal transduction; Testis; Toxicology

Indexed keywords

DEATH RECEPTOR 5; FAS ANTIGEN; FAS ASSOCIATED DEATH DOMAIN PROTEIN; FLICE INHIBITORY PROTEIN; PHTHALIC ACID 2 ETHYLHEXYL MONOESTER; PROTEIN P53;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; EFFECTOR CELL; GERM CELL; MALE; MOUSE; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN LOCALIZATION; PROTEIN PROCESSING; PROTEIN STABILITY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SERTOLI CELL; SIGNAL TRANSDUCTION; TESTIS CELL; TRANSCRIPTION REGULATION;

ANIMALS; ANTIGENS, CD95; APOPTOSIS; CASP8 AND FADD-LIKE APOPTOSIS REGULATING PROTEIN; CASPASE 8; CASPASES; DIETHYLHEXYL PHTHALATE; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; RECEPTORS, TNF-RELATED APOPTOSIS-INDUCING LIGAND; RECEPTORS, TUMOR NECROSIS FACTOR; RNA, MESSENGER; SERTOLI CELLS; SPERMATOZOA; TESTIS; TUMOR SUPPRESSOR PROTEIN P53; UP-REGULATION;

ANIMALIA;

EID: 10944232852     PISSN: 00063363     EISSN: None     Source Type: Journal    
DOI: 10.1095/biolreprod.104.030858     Document Type: Article

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