Carnosol and carnosic acids from Salvia officinalis inhibit microsomal prostaglandin E2 synthase-1

Journal of Pharmacology and Experimental Therapeutics

Volumn 342, Issue 1, 2012, Pages 169-176

  Bauer, Julia ^a   Kuehnl, Susanne ^b   Rollinger, Judith M ^b   Scherer, Olga ^d   Northoff, Hinnak ^c   Stuppner, Hermann ^b   Werz, Oliver ^d   Koeberle, Andreas ^d  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b UNIVERSITY OF INNSBRUCK   (Austria)

^c UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

^d FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

12 HYDROXY 5 CIS 8,10 TRANS HEPTADECATRIENOIC ACID; 6 KETO PROSTAGLANDIN F1 ALPHA; ACETIC ACID ETHYL ESTER; CARNOSIC ACID; CARNOSOL; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; LIPOPOLYSACCHARIDE; PROSTAGLANDIN E2 SYNTHASE 1; PROSTAGLANDIN SYNTHASE; PROSTANOID; SALVIA OFFICINALIS EXTRACT; THROMBOXANE B2; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; BLOOD ANALYSIS; CELL FREE SYSTEM; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG POTENCY; DRUG SELECTIVITY; DRUG TARGETING; ENZYME ACTIVITY; ENZYME INHIBITION; FRACTIONATION; HUMAN; HUMAN CELL; IC 50; MICROSOME; PHYTOCHEMISTRY; PLANT LEAF; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS INHIBITION;

CELL LINE, TUMOR; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; DINOPROSTONE; DITERPENES, ABIETANE; HUMANS; INTRAMOLECULAR OXIDOREDUCTASES; MICROSOMES; PLANT EXTRACTS; PLANT LEAVES; PROSTAGLANDINS; SALVIA OFFICINALIS;

EID: 84862489794     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.112.193847     Document Type: Article

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