Suppression of COX-2, IL-1β and TNF-α expression and leukocyte infiltration in inflamed skin by bioactive compounds from Rosmarinus officinalis L.

Fitoterapia

Volumn 82, Issue 3, 2011, Pages 414-421

  Mengoni, Eleonora S ^a   Vichera, Gabriel ^a   Rigano, Luciano A ^a   Rodriguez Puebla, Marcelo L ^b   Galliano, Silvia R ^c   Cafferata, Eduardo E ^d   Pivetta, Omar H ^e   Moreno, Sivia ^d   Vojnov, Adrián A ^a  

^a Fundacion Pablo Cassara   (Argentina)

^b NORTH CAROLINA STATE UNIVERSITY   (United States)

^c CEMIC   (Argentina)

^d FUNDACIÓN INSTITUTO LELOIR   (Argentina)

^e UNIVERSIDAD AUSTRAL   (Argentina)

Author keywords

Carnosic acid; Carnosol; Cyclooxygenase; Interleukin; Skin inflammation; Tumor necrosis factor

Indexed keywords

ALCOHOL; CARNOSIC ACID; CARNOSOL; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; FIBRONECTIN; INDOMETACIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1BETA; NITRIC OXIDE; NITRITE; PHORBOL 13 ACETATE 12 MYRISTATE; ROSMARINUS OFFICINALIS EXTRACT; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOSE RESPONSE; DRUG MECHANISM; EPIDERMIS; GENE EXPRESSION; HISTOPATHOLOGY; MACROPHAGE; MALE; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; OTITIS; PAW EDEMA; PLANT LEAF; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ROSEMARY; SKIN INFLAMMATION; SKIN ULCER; SOLVENT EXTRACTION;

ANIMALS; CYCLOOXYGENASE 2 INHIBITORS; DITERPENES, ABIETANE; DOSE-RESPONSE RELATIONSHIP, DRUG; FIBRONECTINS; GENE EXPRESSION; INFLAMMATION; INTERCELLULAR ADHESION MOLECULE-1; INTERLEUKIN-1BETA; MACROPHAGES; MALE; MICE; MICE, INBRED BALB C; NEUTROPHIL INFILTRATION; NITRIC OXIDE; PHYTOTHERAPY; PLANT EXTRACTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; ROSMARINUS; SKIN; TETRADECANOYLPHORBOL ACETATE; TUMOR NECROSIS FACTOR-ALPHA;

MURINAE; MUS; ROSMARINUS OFFICINALIS;

EID: 79951672680     PISSN: 0367326X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fitote.2010.11.023     Document Type: Article

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