-
1
-
-
51549087131
-
Multitargeted therapy of cancer by green tea polyphenols
-
Khan N., and Mukhtar H. Multitargeted therapy of cancer by green tea polyphenols. Cancer Lett. 269 (2008) 269-280
-
(2008)
Cancer Lett.
, vol.269
, pp. 269-280
-
-
Khan, N.1
Mukhtar, H.2
-
2
-
-
0033213758
-
Inhibition of cyclin-dependent kinases 2 and 4 activities as well as induction of Cdk inhibitors p21 and p27 during growth arrest of human breast carcinoma cells by (-)-epigallocatechin-3-gallate
-
Liang Y.C., Lin-Shiau S.Y., Chen C.F., and Lin J.K. Inhibition of cyclin-dependent kinases 2 and 4 activities as well as induction of Cdk inhibitors p21 and p27 during growth arrest of human breast carcinoma cells by (-)-epigallocatechin-3-gallate. J. Cell. Biochem. 75 (1999) 1-12
-
(1999)
J. Cell. Biochem.
, vol.75
, pp. 1-12
-
-
Liang, Y.C.1
Lin-Shiau, S.Y.2
Chen, C.F.3
Lin, J.K.4
-
3
-
-
0030799810
-
(-)-Epigallocatechin-3-gallate blocks the induction of nitric oxide synthase by down-regulating lipopolysaccharide-induced activity of transcription factor nuclear factor-kappaB
-
Lin Y.L., and Lin J.K. (-)-Epigallocatechin-3-gallate blocks the induction of nitric oxide synthase by down-regulating lipopolysaccharide-induced activity of transcription factor nuclear factor-kappaB. Mol. Pharmacol. 52 (1997) 465-472
-
(1997)
Mol. Pharmacol.
, vol.52
, pp. 465-472
-
-
Lin, Y.L.1
Lin, J.K.2
-
4
-
-
0030799429
-
Inhibition of tumor promoter-induced activator protein 1 activation and cell transformation by tea polyphenols, (-)-epigallocatechin gallate, and theaflavins
-
Dong Z., Ma W., Huang C., and Yang C.S. Inhibition of tumor promoter-induced activator protein 1 activation and cell transformation by tea polyphenols, (-)-epigallocatechin gallate, and theaflavins. Cancer Res. 57 (1997) 4414-4419
-
(1997)
Cancer Res.
, vol.57
, pp. 4414-4419
-
-
Dong, Z.1
Ma, W.2
Huang, C.3
Yang, C.S.4
-
5
-
-
0035918278
-
Ester bond-containing tea polyphenols potently inhibit proteasome activity in vitro and in vivo
-
Nam S., Smith D.M., and Dou Q.P. Ester bond-containing tea polyphenols potently inhibit proteasome activity in vitro and in vivo. J. Biol. Chem. 276 (2001) 13322-13330
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 13322-13330
-
-
Nam, S.1
Smith, D.M.2
Dou, Q.P.3
-
6
-
-
33645094927
-
Targeting multiple signaling pathways by green tea polyphenol (-)-epigallocatechin-3-gallate
-
Khan N., Afaq F., Saleem M., Ahmad N., and Mukhtar H. Targeting multiple signaling pathways by green tea polyphenol (-)-epigallocatechin-3-gallate. Cancer Res. 66 (2006) 2500-2505
-
(2006)
Cancer Res.
, vol.66
, pp. 2500-2505
-
-
Khan, N.1
Afaq, F.2
Saleem, M.3
Ahmad, N.4
Mukhtar, H.5
-
7
-
-
0035503939
-
Effects of purified green and black tea polyphenols on cyclooxygenase- and lipoxygenase-dependent metabolism of arachidonic acid in human colon mucosa and colon tumor tissues
-
Hong J., Smith T.J., Ho C.T., August D.A., and Yang C.S. Effects of purified green and black tea polyphenols on cyclooxygenase- and lipoxygenase-dependent metabolism of arachidonic acid in human colon mucosa and colon tumor tissues. Biochem. Pharmacol. 62 (2001) 1175-1183
-
(2001)
Biochem. Pharmacol.
, vol.62
, pp. 1175-1183
-
-
Hong, J.1
Smith, T.J.2
Ho, C.T.3
August, D.A.4
Yang, C.S.5
-
8
-
-
56949101468
-
PCR differential display-based identification of regulator of G protein signaling 10 as the target gene in human colon cancer cells induced by black tea polyphenol theaflavin monogallate
-
Lu J., Gosslau A., Liu A.Y., and Chen K.Y. PCR differential display-based identification of regulator of G protein signaling 10 as the target gene in human colon cancer cells induced by black tea polyphenol theaflavin monogallate. Eur. J. Pharmacol. 601 (2008) 66-72
-
(2008)
Eur. J. Pharmacol.
, vol.601
, pp. 66-72
-
-
Lu, J.1
Gosslau, A.2
Liu, A.Y.3
Chen, K.Y.4
-
9
-
-
0037108115
-
Green tea polyphenol epigallocatechin-3-gallate inhibits the IL-1 beta-induced activity and expression of cyclooxygenase-2 and nitric oxide synthase-2 in human chondrocytes
-
Ahmed S., Rahman A., Hasnain A., Lalonde M., Goldberg V.M., and Haqqi T.M. Green tea polyphenol epigallocatechin-3-gallate inhibits the IL-1 beta-induced activity and expression of cyclooxygenase-2 and nitric oxide synthase-2 in human chondrocytes. Free Radic. Biol. Med. 33 (2002) 1097-1105
-
(2002)
Free Radic. Biol. Med.
, vol.33
, pp. 1097-1105
-
-
Ahmed, S.1
Rahman, A.2
Hasnain, A.3
Lalonde, M.4
Goldberg, V.M.5
Haqqi, T.M.6
-
10
-
-
11144333537
-
Green tea constituent epigallocatechin-3-gallate selectively inhibits COX-2 without affecting COX-1 expression in human prostate carcinoma cells
-
Hussain T., Gupta S., Adhami V.M., and Mukhtar H. Green tea constituent epigallocatechin-3-gallate selectively inhibits COX-2 without affecting COX-1 expression in human prostate carcinoma cells. Int. J. Cancer 113 (2005) 660-669
-
(2005)
Int. J. Cancer
, vol.113
, pp. 660-669
-
-
Hussain, T.1
Gupta, S.2
Adhami, V.M.3
Mukhtar, H.4
-
11
-
-
27744566477
-
Epigallocatechin-3-gallate impairs chemokine production in human colon epithelial cell lines
-
Porath D., Riegger C., Drewe J., and Schwager J. Epigallocatechin-3-gallate impairs chemokine production in human colon epithelial cell lines. J. Pharmacol. Exp. Ther. 315 (2005) 1172-1180
-
(2005)
J. Pharmacol. Exp. Ther.
, vol.315
, pp. 1172-1180
-
-
Porath, D.1
Riegger, C.2
Drewe, J.3
Schwager, J.4
-
12
-
-
33646719549
-
Green tea polyphenol (-)-epigallocatechin-3-gallate inhibits cyclooxygenase-2 expression in colon carcinogenesis
-
Peng G., Dixon D.A., Muga S.J., Smith T.J., and Wargovich M.J. Green tea polyphenol (-)-epigallocatechin-3-gallate inhibits cyclooxygenase-2 expression in colon carcinogenesis. Mol. Carcinog. 45 (2006) 309-319
-
(2006)
Mol. Carcinog.
, vol.45
, pp. 309-319
-
-
Peng, G.1
Dixon, D.A.2
Muga, S.J.3
Smith, T.J.4
Wargovich, M.J.5
-
13
-
-
0034692689
-
Regulation of prostaglandin E2 biosynthesis by inducible membrane-associated prostaglandin E2 synthase that acts in concert with cyclooxygenase-2
-
Murakami M., Naraba H., Tanioka T., Semmyo N., Nakatani Y., Kojima F., Ikeda T., Fueki M., Ueno A., Oh S., and Kudo I. Regulation of prostaglandin E2 biosynthesis by inducible membrane-associated prostaglandin E2 synthase that acts in concert with cyclooxygenase-2. J. Biol. Chem. 275 (2000) 32783-32792
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 32783-32792
-
-
Murakami, M.1
Naraba, H.2
Tanioka, T.3
Semmyo, N.4
Nakatani, Y.5
Kojima, F.6
Ikeda, T.7
Fueki, M.8
Ueno, A.9
Oh, S.10
Kudo, I.11
-
14
-
-
0033755897
-
Coordinate up- and down-regulation of glutathione-dependent prostaglandin E synthase and cyclooxygenase-2 in A549 cells. Inhibition by NS-398 and leukotriene C4
-
Thoren S., and Jakobsson P.J. Coordinate up- and down-regulation of glutathione-dependent prostaglandin E synthase and cyclooxygenase-2 in A549 cells. Inhibition by NS-398 and leukotriene C4. Eur. J. Biochem. 267 (2000) 6428-6434
-
(2000)
Eur. J. Biochem.
, vol.267
, pp. 6428-6434
-
-
Thoren, S.1
Jakobsson, P.J.2
-
15
-
-
33745266737
-
Prostaglandin E2 synthesis and secretion: the role of PGE2 synthases
-
Park J.Y., Pillinger M.H., and Abramson S.B. Prostaglandin E2 synthesis and secretion: the role of PGE2 synthases. Clin. Immunol. 119 (2006) 229-240
-
(2006)
Clin. Immunol.
, vol.119
, pp. 229-240
-
-
Park, J.Y.1
Pillinger, M.H.2
Abramson, S.B.3
-
16
-
-
0034693050
-
Molecular identification of cytosolic prostaglandin E2 synthase that is functionally coupled with cyclooxygenase-1 in immediate prostaglandin E2 biosynthesis
-
Tanioka T., Nakatani Y., Semmyo N., Murakami M., and Kudo I. Molecular identification of cytosolic prostaglandin E2 synthase that is functionally coupled with cyclooxygenase-1 in immediate prostaglandin E2 biosynthesis. J. Biol. Chem. 275 (2000) 32775-32782
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 32775-32782
-
-
Tanioka, T.1
Nakatani, Y.2
Semmyo, N.3
Murakami, M.4
Kudo, I.5
-
17
-
-
62849092994
-
Microsomal prostaglandin E synthase-2 is not essential for in vivo prostaglandin E2 biosynthesis
-
Jania L.A., Chandrasekharan S., Backlund M.G., Foley N.A., Snouwaert J., Wang I.M., Clark P., Audoly L.P., and Koller B.H. Microsomal prostaglandin E synthase-2 is not essential for in vivo prostaglandin E2 biosynthesis. Prostaglandins Other Lipid Mediat. 88 (2009) 73-81
-
(2009)
Prostaglandins Other Lipid Mediat.
, vol.88
, pp. 73-81
-
-
Jania, L.A.1
Chandrasekharan, S.2
Backlund, M.G.3
Foley, N.A.4
Snouwaert, J.5
Wang, I.M.6
Clark, P.7
Audoly, L.P.8
Koller, B.H.9
-
18
-
-
34249729416
-
Prostaglandin E receptors
-
Sugimoto Y., and Narumiya S. Prostaglandin E receptors. J. Biol. Chem. 282 (2007) 11613-11617
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 11613-11617
-
-
Sugimoto, Y.1
Narumiya, S.2
-
19
-
-
29244449354
-
Prostaglandins and cancer
-
Wang D., and Dubois R.N. Prostaglandins and cancer. Gut 55 (2006) 115-122
-
(2006)
Gut
, vol.55
, pp. 115-122
-
-
Wang, D.1
Dubois, R.N.2
-
20
-
-
0027482237
-
The 85-kDa, arachidonic acid-specific phospholipase A2 is expressed as an activated phosphoprotein in Sf9 cells
-
de Carvalho M.S., McCormack F.X., and Leslie C.C. The 85-kDa, arachidonic acid-specific phospholipase A2 is expressed as an activated phosphoprotein in Sf9 cells. Arch. Biochem. Biophys. 306 (1993) 534-540
-
(1993)
Arch. Biochem. Biophys.
, vol.306
, pp. 534-540
-
-
de Carvalho, M.S.1
McCormack, F.X.2
Leslie, C.C.3
-
21
-
-
0023904857
-
Picomole determination of 2,4-dimethoxyanilides of prostaglandins by high-performance liquid chromatography with electrochemical detection
-
Knospe J., Steinhilber D., Herrmann T., and Roth H.J. Picomole determination of 2,4-dimethoxyanilides of prostaglandins by high-performance liquid chromatography with electrochemical detection. J. Chromatogr. 442 (1988) 444-450
-
(1988)
J. Chromatogr.
, vol.442
, pp. 444-450
-
-
Knospe, J.1
Steinhilber, D.2
Herrmann, T.3
Roth, H.J.4
-
22
-
-
52649119793
-
Licofelone suppresses prostaglandin E2 formation by interference with the inducible microsomal prostaglandin E2 synthase-1
-
Koeberle A., Siemoneit U., Buehring U., Northoff H., Laufer S., Albrecht W., and Werz O. Licofelone suppresses prostaglandin E2 formation by interference with the inducible microsomal prostaglandin E2 synthase-1. J. Pharmacol. Exp. Ther. 326 (2008) 975-982
-
(2008)
J. Pharmacol. Exp. Ther.
, vol.326
, pp. 975-982
-
-
Koeberle, A.1
Siemoneit, U.2
Buehring, U.3
Northoff, H.4
Laufer, S.5
Albrecht, W.6
Werz, O.7
-
23
-
-
67650628023
-
Myrtucommulone, a natural acylphloroglucinol, inhibits microsomal prostaglandin E2 synthase-1
-
Koeberle A., Pollastro F., Northoff H., and Werz O. Myrtucommulone, a natural acylphloroglucinol, inhibits microsomal prostaglandin E2 synthase-1. Br. J. Pharmacol. 156 (2009) 952-961
-
(2009)
Br. J. Pharmacol.
, vol.156
, pp. 952-961
-
-
Koeberle, A.1
Pollastro, F.2
Northoff, H.3
Werz, O.4
-
24
-
-
34748817976
-
Membrane prostaglandin E synthase-1: a novel therapeutic target
-
Samuelsson B., Morgenstern R., and Jakobsson P.J. Membrane prostaglandin E synthase-1: a novel therapeutic target. Pharmacol. Rev. 59 (2007) 207-224
-
(2007)
Pharmacol. Rev.
, vol.59
, pp. 207-224
-
-
Samuelsson, B.1
Morgenstern, R.2
Jakobsson, P.J.3
-
25
-
-
0032491210
-
Membrane penetration of cytosolic phospholipase A2 is necessary for its interfacial catalysis and arachidonate specificity
-
Lichtenbergova L., Yoon E.T., and Cho W. Membrane penetration of cytosolic phospholipase A2 is necessary for its interfacial catalysis and arachidonate specificity. Biochemistry 37 (1998) 14128-14136
-
(1998)
Biochemistry
, vol.37
, pp. 14128-14136
-
-
Lichtenbergova, L.1
Yoon, E.T.2
Cho, W.3
-
26
-
-
0033594963
-
Identification of human prostaglandin E synthase: a microsomal, glutathione-dependent, inducible enzyme, constituting a potential novel drug target
-
Jakobsson P.J., Thoren S., Morgenstern R., and Samuelsson B. Identification of human prostaglandin E synthase: a microsomal, glutathione-dependent, inducible enzyme, constituting a potential novel drug target. Proc. Natl. Acad. Sci. USA 96 (1999) 7220-7225
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 7220-7225
-
-
Jakobsson, P.J.1
Thoren, S.2
Morgenstern, R.3
Samuelsson, B.4
-
27
-
-
0035817264
-
A pyrrolidine-based specific inhibitor of cytosolic phospholipase A(2)alpha blocks arachidonic acid release in a variety of mammalian cells
-
Ghomashchi F., Stewart A., Hefner Y., Ramanadham S., Turk J., Leslie C.C., and Gelb M.H. A pyrrolidine-based specific inhibitor of cytosolic phospholipase A(2)alpha blocks arachidonic acid release in a variety of mammalian cells. Biochim. Biophys. Acta 1513 (2001) 160-166
-
(2001)
Biochim. Biophys. Acta
, vol.1513
, pp. 160-166
-
-
Ghomashchi, F.1
Stewart, A.2
Hefner, Y.3
Ramanadham, S.4
Turk, J.5
Leslie, C.C.6
Gelb, M.H.7
-
28
-
-
0141513666
-
Inhibition of proliferation of human cancer cells and cyclooxygenase enzymes by anthocyanidins and catechins
-
Seeram N.P., Zhang Y., and Nair M.G. Inhibition of proliferation of human cancer cells and cyclooxygenase enzymes by anthocyanidins and catechins. Nutr. Cancer 46 (2003) 101-106
-
(2003)
Nutr. Cancer
, vol.46
, pp. 101-106
-
-
Seeram, N.P.1
Zhang, Y.2
Nair, M.G.3
-
29
-
-
35848954713
-
Substituted phenanthrene imidazoles as potent, selective, and orally active mPGES-1 inhibitors
-
Cote B., Boulet L., Brideau C., Claveau D., Ethier D., Frenette R., Gagnon M., Giroux A., Guay J., Guiral S., Mancini J., Martins E., Masse F., Methot N., Riendeau D., Rubin J., Xu D., Yu H., Ducharme Y., and Friesen R.W. Substituted phenanthrene imidazoles as potent, selective, and orally active mPGES-1 inhibitors. Bioorg. Med. Chem. Lett. 17 (2007) 6816-6820
-
(2007)
Bioorg. Med. Chem. Lett.
, vol.17
, pp. 6816-6820
-
-
Cote, B.1
Boulet, L.2
Brideau, C.3
Claveau, D.4
Ethier, D.5
Frenette, R.6
Gagnon, M.7
Giroux, A.8
Guay, J.9
Guiral, S.10
Mancini, J.11
Martins, E.12
Masse, F.13
Methot, N.14
Riendeau, D.15
Rubin, J.16
Xu, D.17
Yu, H.18
Ducharme, Y.19
Friesen, R.W.20
more..
-
30
-
-
44849085464
-
Genetic deletion of mPGES-1 suppresses intestinal tumorigenesis
-
Nakanishi M., Montrose D.C., Clark P., Nambiar P.R., Belinsky G.S., Claffey K.P., Xu D., and Rosenberg D.W. Genetic deletion of mPGES-1 suppresses intestinal tumorigenesis. Cancer Res. 68 (2008) 3251-3259
-
(2008)
Cancer Res.
, vol.68
, pp. 3251-3259
-
-
Nakanishi, M.1
Montrose, D.C.2
Clark, P.3
Nambiar, P.R.4
Belinsky, G.S.5
Claffey, K.P.6
Xu, D.7
Rosenberg, D.W.8
-
31
-
-
42149154618
-
Microsomal prostaglandin E synthase-1 inhibition in cardiovascular inflammatory disease
-
Wang M., Song W.L., Cheng Y., and Fitzgerald G.A. Microsomal prostaglandin E synthase-1 inhibition in cardiovascular inflammatory disease. J. Intern. Med. 263 (2008) 500-505
-
(2008)
J. Intern. Med.
, vol.263
, pp. 500-505
-
-
Wang, M.1
Song, W.L.2
Cheng, Y.3
Fitzgerald, G.A.4
-
32
-
-
20444480574
-
Effects of dosing condition on the oral bioavailability of green tea catechins after single-dose administration of Polyphenon E in healthy individuals
-
Chow H.H., Hakim I.A., Vining D.R., Crowell J.A., Ranger-Moore J., Chew W.M., Celaya C.A., Rodney S.R., Hara Y., and Alberts D.S. Effects of dosing condition on the oral bioavailability of green tea catechins after single-dose administration of Polyphenon E in healthy individuals. Clin. Cancer Res. 11 (2005) 4627-4633
-
(2005)
Clin. Cancer Res.
, vol.11
, pp. 4627-4633
-
-
Chow, H.H.1
Hakim, I.A.2
Vining, D.R.3
Crowell, J.A.4
Ranger-Moore, J.5
Chew, W.M.6
Celaya, C.A.7
Rodney, S.R.8
Hara, Y.9
Alberts, D.S.10
-
33
-
-
0033693115
-
Differential effects of theaflavin monogallates on cell growth, apoptosis, and Cox-2 gene expression in cancerous versus normal cells
-
Lu J., Ho C.T., Ghai G., and Chen K.Y. Differential effects of theaflavin monogallates on cell growth, apoptosis, and Cox-2 gene expression in cancerous versus normal cells. Cancer Res. 60 (2000) 6465-6471
-
(2000)
Cancer Res.
, vol.60
, pp. 6465-6471
-
-
Lu, J.1
Ho, C.T.2
Ghai, G.3
Chen, K.Y.4
-
34
-
-
0242694875
-
Inhibition of phorbol ester-induced COX-2 expression by epigallocatechin gallate in mouse skin and cultured human mammary epithelial cells
-
Kundu J.K., Na H.K., Chun K.S., Kim Y.K., Lee S.J., Lee S.S., Lee O.S., Sim Y.C., and Surh Y.J. Inhibition of phorbol ester-induced COX-2 expression by epigallocatechin gallate in mouse skin and cultured human mammary epithelial cells. J. Nutr. 133 (2003) 3805S-3810S
-
(2003)
J. Nutr.
, vol.133
-
-
Kundu, J.K.1
Na, H.K.2
Chun, K.S.3
Kim, Y.K.4
Lee, S.J.5
Lee, S.S.6
Lee, O.S.7
Sim, Y.C.8
Surh, Y.J.9
-
35
-
-
22744459749
-
EGCG inhibits activation of HER3 and expression of cyclooxygenase-2 in human colon cancer cells
-
Shimizu M., Deguchi A., Joe A.K., McKoy J.F., Moriwaki H., and Weinstein I.B. EGCG inhibits activation of HER3 and expression of cyclooxygenase-2 in human colon cancer cells. J. Exp. Ther. Oncol. 5 (2005) 69-78
-
(2005)
J. Exp. Ther. Oncol.
, vol.5
, pp. 69-78
-
-
Shimizu, M.1
Deguchi, A.2
Joe, A.K.3
McKoy, J.F.4
Moriwaki, H.5
Weinstein, I.B.6
-
36
-
-
0033070601
-
Polyphenolic antioxidant (-)-epigallocatechin-3-gallate from green tea reduces UVB-induced inflammatory responses and infiltration of leukocytes in human skin
-
Katiyar S.K., Matsui M.S., Elmets C.A., and Mukhtar H. Polyphenolic antioxidant (-)-epigallocatechin-3-gallate from green tea reduces UVB-induced inflammatory responses and infiltration of leukocytes in human skin. Photochem. Photobiol. 69 (1999) 148-153
-
(1999)
Photochem. Photobiol.
, vol.69
, pp. 148-153
-
-
Katiyar, S.K.1
Matsui, M.S.2
Elmets, C.A.3
Mukhtar, H.4
-
37
-
-
0034600758
-
Epigallocatechin gallate increase the prostacyclin production of bovine aortic endothelial cells
-
Mizugaki M., Ishizawa F., Yamazaki T., and Hishinuma T. Epigallocatechin gallate increase the prostacyclin production of bovine aortic endothelial cells. Prostaglandins Other Lipid Mediat. 62 (2000) 157-164
-
(2000)
Prostaglandins Other Lipid Mediat.
, vol.62
, pp. 157-164
-
-
Mizugaki, M.1
Ishizawa, F.2
Yamazaki, T.3
Hishinuma, T.4
|