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Volumn , Issue , 2012, Pages

Oxidative stress, tumor microenvironment, and metabolic reprogramming: A diabolic liaison

Author keywords

[No Author keywords available]

Indexed keywords

GLUTATHIONE PEROXIDASE 3; INTERLEUKIN 6; REACTIVE OXYGEN METABOLITE; SCATTER FACTOR; SELENIUM TRANSPORTER SELENOPROTEIN P PLASMA 1; SELENOPROTEIN P; THIOREDOXIN REDUCTASE 1; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; VASCULOTROPIN;

EID: 84862292292     PISSN: 16878876     EISSN: 16878884     Source Type: Journal    
DOI: 10.1155/2012/762825     Document Type: Review
Times cited : (252)

References (92)
  • 1
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D., Weinberg R. A., The hallmarks of cancer Cell 2000 100 1 57 70 (Pubitemid 30046295)
    • (2000) Cell , vol.100 , Issue.1 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 2
    • 78649997911 scopus 로고    scopus 로고
    • Jekyll and hyde: The role of the microenvironment on the progression of cancer
    • Allen M., Jones J. L., Jekyll and hyde: the role of the microenvironment on the progression of cancer The Journal of Pathology 2011 223 2 162 176
    • (2011) The Journal of Pathology , vol.223 , Issue.2 , pp. 162-176
    • Allen, M.1    Jones, J.L.2
  • 4
    • 67349267711 scopus 로고    scopus 로고
    • Redox regulation of anoikis resistance of metastatic prostate cancer cells: Key role for Src and EGFR-mediated pro-survival signals
    • Giannoni E., Fiaschi T., Ramponi G., Chiarugi P., Redox regulation of anoikis resistance of metastatic prostate cancer cells: key role for Src and EGFR-mediated pro-survival signals Oncogene 2009 28 20 2074 2086
    • (2009) Oncogene , vol.28 , Issue.20 , pp. 2074-2086
    • Giannoni, E.1    Fiaschi, T.2    Ramponi, G.3    Chiarugi, P.4
  • 5
    • 79954999152 scopus 로고    scopus 로고
    • Signalling pathways involved in endocrine resistance in breast cancer and associations with epithelial to mesenchymal transition (review)
    • Al Saleh S., Sharaf L. H., Luqmani Y. A., Signalling pathways involved in endocrine resistance in breast cancer and associations with epithelial to mesenchymal transition (review) International Journal of Oncology 2011 38 5 1197 1217
    • (2011) International Journal of Oncology , vol.38 , Issue.5 , pp. 1197-1217
    • Al Saleh, S.1    Sharaf, L.H.2    Luqmani, Y.A.3
  • 6
    • 49749097982 scopus 로고    scopus 로고
    • Impact of antioxidant supplementation on chemotherapeutic toxicity: A systematic review of the evidence from randomized controlled trials
    • Block K. I., Koch A. C., Mead M. N., Tothy P. K., Newman R. A., Gyllenhaal C., Impact of antioxidant supplementation on chemotherapeutic toxicity: a systematic review of the evidence from randomized controlled trials International Journal of Cancer 2008 123 6 1227 1239
    • (2008) International Journal of Cancer , vol.123 , Issue.6 , pp. 1227-1239
    • Block, K.I.1    Koch, A.C.2    Mead, M.N.3    Tothy, P.K.4    Newman, R.A.5    Gyllenhaal, C.6
  • 9
    • 81255188940 scopus 로고    scopus 로고
    • Tumor angiogenesis: Molecular pathways and therapeutic targets
    • Weis S. M., Cheresh D. A., Tumor angiogenesis: molecular pathways and therapeutic targets Nature Medicine 2011 17 11 1359 1370
    • (2011) Nature Medicine , vol.17 , Issue.11 , pp. 1359-1370
    • Weis, S.M.1    Cheresh, D.A.2
  • 10
    • 81855169565 scopus 로고    scopus 로고
    • Cancer invasion and the microenvironment: Plasticity and reciprocity
    • Friedl P., Alexander S., Cancer invasion and the microenvironment: plasticity and reciprocity Cell 2011 147 5 992 1009
    • (2011) Cell , vol.147 , Issue.5 , pp. 992-1009
    • Friedl, P.1    Alexander, S.2
  • 11
    • 17244367828 scopus 로고    scopus 로고
    • Reactive oxygen species in tumor progression
    • Storz P., Reactive oxygen species in tumor progression Frontiers in Bioscience 2005 10 2 1881 1896 (Pubitemid 40529044)
    • (2005) Frontiers in Bioscience , vol.10 , Issue.2 , pp. 1881-1896
    • Storz, P.1
  • 12
    • 77954562833 scopus 로고    scopus 로고
    • Metastasis: Cancer cell's escape from oxidative stress
    • Pani G., Galeotti T., Chiarugi P., Metastasis: cancer cell's escape from oxidative stress Cancer and Metastasis Reviews 2010 29 2 351 378
    • (2010) Cancer and Metastasis Reviews , vol.29 , Issue.2 , pp. 351-378
    • Pani, G.1    Galeotti, T.2    Chiarugi, P.3
  • 13
    • 0034623990 scopus 로고    scopus 로고
    • A redox signaling mechanism for density-dependent inhibition of cell growth
    • DOI 10.1074/jbc.M007319200
    • Pani G., Colavitti R., Bedogni B., Anzevino R., Borrello S., Galeotti T., A redox signaling mechanism for density-dependent inhibition of cell growth The Journal of Biological Chemistry 2000 275 49 38891 38899 (Pubitemid 32010745)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.49 , pp. 38891-38899
    • Pani, G.1    Colavitti, R.2    Bedogni, B.3    Anzevino, R.4    Borrello, S.5    Galeotti, T.6
  • 14
    • 0034633602 scopus 로고    scopus 로고
    • Hydrogen peroxide: A key messenger that modulates protein phosphorylation through cysteine oxidation
    • ARTICLE PE1
    • Rhee S. G., Bae Y. S., Lee S. R., Kwon J., Hydrogen peroxide: a key messenger that modulates protein phosphorylation through cysteine oxidation Science Signaling 2000 2000 53, article pe1
    • (2000) Science Signaling , vol.2000 , Issue.53
    • Rhee, S.G.1    Bae, Y.S.2    Lee, S.R.3    Kwon, J.4
  • 15
    • 33745534837 scopus 로고    scopus 로고
    • Pro-metastatic signaling by c-Met through RAC-1 and reactive oxygen species (ROS)
    • DOI 10.1038/sj.onc.1209409, PII 1209409
    • Ferraro D., Corso S., Fasano E., Panieri E., Santangelo R., Borrello S., Giordano S., Pani G., Galeotti T., Pro-metastatic signaling by c-met through RAC-1 and reactive oxygen species (ROS) Oncogene 2006 25 26 3689 3698 (Pubitemid 43980490)
    • (2006) Oncogene , vol.25 , Issue.26 , pp. 3689-3698
    • Ferraro, D.1    Corso, S.2    Fasano, E.3    Panieri, E.4    Santangelo, R.5    Borrello, S.6    Giordano, S.7    Pani, G.8    Galeotti, T.9
  • 16
    • 84859822323 scopus 로고    scopus 로고
    • EMT and oxidative stress: A bidirectional interplay affecting tumor malignancy
    • Giannoni E., Parri M., Chiarugi P., EMT and oxidative stress: a bidirectional interplay affecting tumor malignancy Antioxidants Redox Signaling 2012 16 11 1248 1263
    • (2012) Antioxidants Redox Signaling , vol.16 , Issue.11 , pp. 1248-1263
    • Giannoni, E.1    Parri, M.2    Chiarugi, P.3
  • 17
  • 18
    • 48549089006 scopus 로고    scopus 로고
    • The role of reactive oxygen species in integrin and matrix metalloproteinase expression and function
    • Svineng G., Ravuri C., Rikardsen O., Huseby N. E., Winberg J. O., The role of reactive oxygen species in integrin and matrix metalloproteinase expression and function Connective Tissue Research 2008 49 3-4 197 202
    • (2008) Connective Tissue Research , vol.49 , Issue.34 , pp. 197-202
    • Svineng, G.1    Ravuri, C.2    Rikardsen, O.3    Huseby, N.E.4    Winberg, J.O.5
  • 19
    • 3042822263 scopus 로고    scopus 로고
    • Telomere length mediates the effects of telomerase on the cellular response to genotoxic stress
    • DOI 10.1016/j.yexcr.2004.04.004, PII S0014482704002010
    • Rubio M. A., Davalos A. R., Campisi J., Telomere length mediates the effects of telomerase on the cellular response to genotoxic stress Experimental Cell Research 2004 298 1 17 27 (Pubitemid 38887303)
    • (2004) Experimental Cell Research , vol.298 , Issue.1 , pp. 17-27
    • Rubio, M.A.1    Davalos, A.R.2    Campisi, J.3
  • 20
    • 0036775442 scopus 로고    scopus 로고
    • Redox signaling of angiogenesis
    • Maulik N., Redox signaling of angiogenesis Antioxidants Redox Signaling 2002 4 5 805 815 (Pubitemid 35246944)
    • (2002) Antioxidants and Redox Signaling , vol.4 , Issue.5 , pp. 805-815
    • Maulik, N.1
  • 21
    • 70349368518 scopus 로고    scopus 로고
    • Novel role of NADPH oxidase in angiogenesis and stem/progenitor cell function
    • Ushio-Fukai M., Urao N., Novel role of NADPH oxidase in angiogenesis and stem/progenitor cell function Antioxidants Redox Signaling 2009 11 10 2517 2533
    • (2009) Antioxidants Redox Signaling , vol.11 , Issue.10 , pp. 2517-2533
    • Ushio-Fukai, M.1    Urao, N.2
  • 23
    • 46749127860 scopus 로고    scopus 로고
    • From anchorage dependent proliferation to survival: Lessons from redox signalling
    • Chiarugi P., From anchorage dependent proliferation to survival: lessons from redox signalling International Union of Biochemistry and Molecular Biology 2008 60 5 301 307
    • (2008) International Union of Biochemistry and Molecular Biology , vol.60 , Issue.5 , pp. 301-307
    • Chiarugi, P.1
  • 24
    • 0033517189 scopus 로고    scopus 로고
    • NF- B activation by tumour necrosis factor requires tie akt serine- threonine kinase
    • Ozes O. N., Mayo L. D., Gustin J. A., Pfeffer S. R., Pfeffer L. M., Donner D. B., NF- B activation by tumour necrosis factor requires tie akt serine- threonine kinase Nature 1999 401 6748 82 85
    • (1999) Nature , vol.401 , Issue.6748 , pp. 82-85
    • Ozes, O.N.1    Mayo, L.D.2    Gustin, J.A.3    Pfeffer, S.R.4    Pfeffer, L.M.5    Donner, D.B.6
  • 26
    • 80052751477 scopus 로고    scopus 로고
    • Pyruvate kinase triggers a metabolic feedback loop that controls redox metabolism in respiring cells
    • Gruning N. M., Rinnerthaler M., Bluemlein K., Pyruvate kinase triggers a metabolic feedback loop that controls redox metabolism in respiring cells Cell Metabolism 2011 14 3 415 427
    • (2011) Cell Metabolism , vol.14 , Issue.3 , pp. 415-427
    • Gruning, N.M.1    Rinnerthaler, M.2    Bluemlein, K.3
  • 27
    • 76349095132 scopus 로고    scopus 로고
    • Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics
    • Semenza G. L., Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics Oncogene 2010 29 5 625 634
    • (2010) Oncogene , vol.29 , Issue.5 , pp. 625-634
    • Semenza, G.L.1
  • 29
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • Hanahan D., Weinberg R. A., Hallmarks of cancer: the next generation Cell 2011 144 5 646 674
    • (2011) Cell , vol.144 , Issue.5 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 30
    • 0034011261 scopus 로고    scopus 로고
    • Oxyradicals and DNA damage
    • Marnett L. J., Oxyradicals and DNA damage Carcinogenesis 2000 21 3 361 370 (Pubitemid 30137921)
    • (2000) Carcinogenesis , vol.21 , Issue.3 , pp. 361-370
    • Marnett, L.J.1
  • 31
    • 77950346282 scopus 로고    scopus 로고
    • Immunity, inflammation, and cancer
    • Grivennikov S. I., Greten F. R., Karin M., Immunity, inflammation, and cancer Cell 2010 140 6 883 899
    • (2010) Cell , vol.140 , Issue.6 , pp. 883-899
    • Grivennikov, S.I.1    Greten, F.R.2    Karin, M.3
  • 33
    • 0021964203 scopus 로고
    • Prooxidant states and tumor promotion
    • Cerutti P. A., Prooxidant states and tumor promotion Science 1985 227 4685 375 381 (Pubitemid 15153495)
    • (1985) Science , vol.227 , Issue.4685 , pp. 375-381
    • Cerutti, P.A.1
  • 34
    • 0037780966 scopus 로고    scopus 로고
    • Reactive oxygen species as essential mediators of cell adhesion: The oxidative inhibition of a FAK tyrosine phosphatase is required for cell adhesion
    • DOI 10.1083/jcb.200211118
    • Chiarugi P., Pani G., Giannoni E., Taddei L., Colavitti R., Raugei G., Symons M., Borrello S., Galeotti T., Ramponi G., Reactive oxygen species as essential mediators of cell adhesion: the oxidative inhibition of a FAK tyrosine phosphatase is required for cell adhesion Journal of Cell Biology 2003 161 5 933 944 (Pubitemid 36718426)
    • (2003) Journal of Cell Biology , vol.161 , Issue.5 , pp. 933-944
    • Chiarugi, P.1    Pani, G.2    Giannoni, E.3    Taddei, L.4    Colavitti, R.5    Raugei, G.6    Symons, M.7    Borrello, S.8    Galeotti, T.9    Ramponi, G.10
  • 35
    • 26444449537 scopus 로고    scopus 로고
    • Roles of reactive oxygen species in angiopoietin-1/tie-2 receptor signaling
    • DOI 10.1096/fj.04-3621fje
    • Harfouche R., Malak N. A., Brandes R. P., Karsan A., Irani K., Hussain S. N. A., Roles of reactive oxygen species in angiopoietin-1/tie-2 receptor signaling The FASEB Journal 2005 19 12 1728 1730 (Pubitemid 41429544)
    • (2005) FASEB Journal , vol.19 , Issue.12 , pp. 1728-1730
    • Harfouche, R.1    Malak, N.A.2    Brandes, R.P.3    Karsan, A.4    Irani, K.5    Hussain, S.N.A.6
  • 37
    • 57249103576 scopus 로고    scopus 로고
    • Epigenetic changes induced by reactive oxygen species in hepatocellular carcinoma: Methylation of the E-cadherin promoter
    • Lim S. O., Gu J. M., Kim M. S., Kim H. S., Park Y. N., Park C. K., Cho J. W., Park Y. M., Jung G., Epigenetic changes induced by reactive oxygen species in hepatocellular carcinoma: methylation of the E-cadherin promoter Gastroenterology 2008 135 6 2128 2140
    • (2008) Gastroenterology , vol.135 , Issue.6 , pp. 2128-2140
    • Lim, S.O.1    Gu, J.M.2    Kim, M.S.3    Kim, H.S.4    Park, Y.N.5    Park, C.K.6    Cho, J.W.7    Park, Y.M.8    Jung, G.9
  • 38
    • 0033105874 scopus 로고    scopus 로고
    • NADPH oxidase: An update
    • Babior B. M., NADPH oxidase: an update Blood 1999 93 5 1464 1476 (Pubitemid 29102471)
    • (1999) Blood , vol.93 , Issue.5 , pp. 1464-1476
    • Babior, B.M.1
  • 39
    • 33847063469 scopus 로고    scopus 로고
    • Redox signalling in anchorage-dependent cell growth
    • DOI 10.1016/j.cellsig.2006.11.009, PII S0898656806003056
    • Chiarugi P., Fiaschi T., Redox signalling in anchorage-dependent cell growth Cellular Signalling 2007 19 4 672 682 (Pubitemid 46275378)
    • (2007) Cellular Signalling , vol.19 , Issue.4 , pp. 672-682
    • Chiarugi, P.1    Fiaschi, T.2
  • 42
    • 31044433663 scopus 로고    scopus 로고
    • Macrophages: Obligate partners for tumor cell migration, invasion, and metastasis
    • DOI 10.1016/j.cell.2006.01.007, PII S0092867406000559
    • Condeelis J., Pollard J. W., Macrophages: obligate partners for tumor cell migration, invasion, and metastasis Cell 2006 124 2 263 266 (Pubitemid 43121975)
    • (2006) Cell , vol.124 , Issue.2 , pp. 263-266
    • Condeelis, J.1    Pollard, J.W.2
  • 43
    • 44449125132 scopus 로고    scopus 로고
    • Reactive oxygen species and angiogenesis: NADPH oxidase as target for cancer therapy
    • DOI 10.1016/j.canlet.2008.02.044, PII S0304383508001432
    • Ushio-Fukai M., Nakamura Y., Reactive oxygen species and angiogenesis: NADPH oxidase as target for cancer therapy Cancer Letters 2008 266 1 37 52 (Pubitemid 351753035)
    • (2008) Cancer Letters , vol.266 , Issue.1 , pp. 37-52
    • Ushio-Fukai, M.1    Nakamura, Y.2
  • 44
    • 24144493814 scopus 로고    scopus 로고
    • Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing
    • DOI 10.1016/j.cmet.2005.05.001, PII S1550413105001397
    • Guzy R. D., Hoyos B., Robin E., Chen H., Liu L., Mansfield K. D., Simon M. C., Hammerling U., Schumacker P. T., Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing Cell Metabolism 2005 1 6 401 408 (Pubitemid 43960623)
    • (2005) Cell Metabolism , vol.1 , Issue.6 , pp. 401-408
    • Guzy, R.D.1    Hoyos, B.2    Robin, E.3    Chen, H.4    Liu, L.5    Mansfield, K.D.6    Simon, M.C.7    Hammerling, U.8    Schumacker, P.T.9
  • 45
    • 70549092785 scopus 로고    scopus 로고
    • Mitochondrial reactive oxygen species regulate hypoxic signaling
    • Hamanaka R. B., Chandel N. S., Mitochondrial reactive oxygen species regulate hypoxic signaling Current Opinion in Cell Biology 2009 21 6 894 899
    • (2009) Current Opinion in Cell Biology , vol.21 , Issue.6 , pp. 894-899
    • Hamanaka, R.B.1    Chandel, N.S.2
  • 46
    • 40949126440 scopus 로고    scopus 로고
    • Mitochondrial complex III regulates hypoxic activation of HIF
    • DOI 10.1038/sj.cdd.4402307, PII 4402307, The biology of Hypoxia-inducible factors
    • Klimova T., Chandel N. S., Mitochondrial complex III regulates hypoxic activation of HIF Cell Death Differentiation 2008 15 4 660 666 (Pubitemid 351405069)
    • (2008) Cell Death and Differentiation , vol.15 , Issue.4 , pp. 660-666
    • Klimova, T.1    Chandel, N.S.2
  • 47
    • 33746886564 scopus 로고    scopus 로고
    • Enhancement of tumor invasion depends on transdifferentiation of skin fibroblasts mediated by reactive oxygen species
    • DOI 10.1242/jcs.03011
    • Cat B., Stuhlmann D., Steinbrenner H., Alili L., Holtktter O., Sies H., Brenneisen P., Enhancement of tumor invasion depends on transdifferentiation of skin fibroblasts mediated by reactive oxygen species Journal of Cell Science 2006 119 13 2727 2738 (Pubitemid 44184009)
    • (2006) Journal of Cell Science , vol.119 , Issue.13 , pp. 2727-2738
    • Cat, B.1    Stuhlmann, D.2    Steinbrenner, H.3    Alili, L.4    Holtkotter, O.5    Sies, H.6    Brenneisen, P.7
  • 48
    • 79957532451 scopus 로고    scopus 로고
    • Cancer associated fibroblasts exploit reactive oxygen species through a proinflammatory signature leading to epithelial mesenchymal transition and stemness
    • Giannoni E., Bianchini F., Calorini L., Chiarugi P., Cancer associated fibroblasts exploit reactive oxygen species through a proinflammatory signature leading to epithelial mesenchymal transition and stemness Antioxidants Redox Signaling 2011 14 12 2361 2371
    • (2011) Antioxidants Redox Signaling , vol.14 , Issue.12 , pp. 2361-2371
    • Giannoni, E.1    Bianchini, F.2    Calorini, L.3    Chiarugi, P.4
  • 49
    • 77949881221 scopus 로고    scopus 로고
    • The senescence-associated secretory phenotype: The dark side of tumor suppression
    • Coppé J. P., Desprez P. Y., Krtolica A., Campisi J., The senescence-associated secretory phenotype: the dark side of tumor suppression Annual Review of Pathology 2010 5 99 118
    • (2010) Annual Review of Pathology , vol.5 , pp. 99-118
    • Coppé, J.P.1    Desprez, P.Y.2    Krtolica, A.3    Campisi, J.4
  • 52
    • 70849093542 scopus 로고    scopus 로고
    • Reactive oxygen species-dependent signaling regulates cancer
    • Weinberg F., Chandel N. S., Reactive oxygen species-dependent signaling regulates cancer Cellular and Molecular Life Sciences 2009 66 23 3663 3673
    • (2009) Cellular and Molecular Life Sciences , vol.66 , Issue.23 , pp. 3663-3673
    • Weinberg, F.1    Chandel, N.S.2
  • 55
    • 77952568396 scopus 로고    scopus 로고
    • Hallmarks of cancer: Interactions with the tumor stroma
    • Pietras K., stman A., Hallmarks of cancer: interactions with the tumor stroma Experimental Cell Research 2010 316 8 1324 1331
    • (2010) Experimental Cell Research , vol.316 , Issue.8 , pp. 1324-1331
    • Pietras, K.1    Stman, A.2
  • 57
    • 77956036249 scopus 로고    scopus 로고
    • NOX4/NADPH oxidase expression is increased in pulmonary fibroblasts from patients with idiopathic pulmonary fibrosis and mediates TGF 1-induced fibroblast differentiation into myofibroblasts
    • Amara N., Goven D., Prost F., Muloway R., Crestani B., Boczkowski J., NOX4/NADPH oxidase expression is increased in pulmonary fibroblasts from patients with idiopathic pulmonary fibrosis and mediates TGF 1-induced fibroblast differentiation into myofibroblasts Thorax 2010 65 8 733 738
    • (2010) Thorax , vol.65 , Issue.8 , pp. 733-738
    • Amara, N.1    Goven, D.2    Prost, F.3    Muloway, R.4    Crestani, B.5    Boczkowski, J.6
  • 59
  • 61
    • 0037180757 scopus 로고    scopus 로고
    • Inflammation and cancer
    • DOI 10.1038/nature01322
    • Coussens L. M., Werb Z., Inflammation and cancer Nature 2002 420 6917 860 867 (Pubitemid 36019639)
    • (2002) Nature , vol.420 , Issue.6917 , pp. 860-867
    • Coussens, L.M.1    Werb, Z.2
  • 62
    • 0034663989 scopus 로고    scopus 로고
    • Hif-1 and human disease: One highly involved factor
    • Semenza G. L., Hif-1 and human disease: one highly involved factor Genes Development 2000 14 16 1983 1991 (Pubitemid 30637348)
    • (2000) Genes and Development , vol.14 , Issue.16 , pp. 1983-1991
    • Semenza, G.L.1
  • 63
    • 58249093939 scopus 로고    scopus 로고
    • How mitochondria produce reactive oxygen species
    • Murphy M. P., How mitochondria produce reactive oxygen species Biochemical Journal 2009 417 1 1 13
    • (2009) Biochemical Journal , vol.417 , Issue.1 , pp. 1-13
    • Murphy, M.P.1
  • 65
    • 24144447915 scopus 로고    scopus 로고
    • Mitochondrial dysfunction resulting from loss of cytochrome c impairs cellular oxygen sensing and hypoxic HIF-alpha activation
    • DOI 10.1016/j.cmet.2005.05.003, PII S1550413105001415
    • Mansfield K. D., Guzy R. D., Pan Y., Young R. M., Cash T. P., Schumacker P. T., Simon M. C., Mitochondrial dysfunction resulting from loss of cytochrome c impairs cellular oxygen sensing and hypoxic HIF- activation Cell Metabolism 2005 1 6 393 399 (Pubitemid 43960625)
    • (2005) Cell Metabolism , vol.1 , Issue.6 , pp. 393-399
    • Mansfield, K.D.1    Guzy, R.D.2    Pan, Y.3    Young, R.M.4    Cash, T.P.5    Schumacker, P.T.6    Simon, M.C.7
  • 66
    • 0036359548 scopus 로고    scopus 로고
    • Hypoxia - A key regulatory factor in tumour growth
    • Harris A. L., Hypoxiaa key regulatory factor in tumour growth Nature Reviews Cancer 2002 2 1 38 47 (Pubitemid 37328806)
    • (2002) Nature Reviews Cancer , vol.2 , Issue.1 , pp. 38-47
    • Harris, A.L.1
  • 67
    • 2342661143 scopus 로고    scopus 로고
    • Intratumoral hypoxia, radiation resistance, and HIF-1
    • DOI 10.1016/S1535-6108(04)00118-7, PII S1535610804001187
    • Semenza G. L., Intratumoral hypoxia, radiation resistance, and HIF-1 Cancer Cell 2004 5 5 405 406 (Pubitemid 38610240)
    • (2004) Cancer Cell , vol.5 , Issue.5 , pp. 405-406
    • Semenza, G.L.1
  • 68
    • 33846117134 scopus 로고    scopus 로고
    • The signaling mechanism of ROS in tumor progression
    • Wu W. S., The signaling mechanism of ROS in tumor progression Cancer and Metastasis Reviews 2006 25 4 695 705
    • (2006) Cancer and Metastasis Reviews , vol.25 , Issue.4 , pp. 695-705
    • Wu, W.S.1
  • 71
    • 65349092794 scopus 로고    scopus 로고
    • Stabilization of snail by NF- B is required for inflammation-induced cell migration and invasion
    • Wu Y., Deng J., Rychahou P. G., Qiu S., Evers B. M., Zhou B. P., Stabilization of snail by NF- B is required for inflammation-induced cell migration and invasion Cancer Cell 2009 15 5 416 428
    • (2009) Cancer Cell , vol.15 , Issue.5 , pp. 416-428
    • Wu, Y.1    Deng, J.2    Rychahou, P.G.3    Qiu, S.4    Evers, B.M.5    Zhou, B.P.6
  • 73
    • 47749131186 scopus 로고    scopus 로고
    • TWIST activation by hypoxia inducible factor-1 (HIF-1): Implications in metastasis and development
    • Yang M. H., Wu K. J., TWIST activation by hypoxia inducible factor-1 (HIF-1): implications in metastasis and development Cell Cycle 2008 7 14 2090 2096
    • (2008) Cell Cycle , vol.7 , Issue.14 , pp. 2090-2096
    • Yang, M.H.1    Wu, K.J.2
  • 74
    • 63049123066 scopus 로고    scopus 로고
    • Transitions between epithelial and mesenchymal states: Acquisition of malignant and stem cell traits
    • Polyak K., Weinberg R. A., Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits Nature Reviews Cancer 2009 9 4 265 273
    • (2009) Nature Reviews Cancer , vol.9 , Issue.4 , pp. 265-273
    • Polyak, K.1    Weinberg, R.A.2
  • 75
    • 0036595629 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in tumor progression
    • Theiry J. P., Epithelial-mesenchymal transitions in tumor progression Nature Reviews Cancer 2002 2 6 442 454
    • (2002) Nature Reviews Cancer , vol.2 , Issue.6 , pp. 442-454
    • Theiry, J.P.1
  • 76
    • 33244463813 scopus 로고    scopus 로고
    • Complex networks orchestrate epithelial-mesenchymal transitions
    • DOI 10.1038/nrm1835, PII NRM1835
    • Thiery J. P., Sleeman J. P., Complex networks orchestrate epithelial-mesenchymal transitions Nature Reviews Molecular Cell Biology 2006 7 2 131 142 (Pubitemid 43278296)
    • (2006) Nature Reviews Molecular Cell Biology , vol.7 , Issue.2 , pp. 131-142
    • Thiery, J.P.1    Sleeman, J.P.2
  • 77
    • 22244492306 scopus 로고    scopus 로고
    • Carcinoma invasion and metastasis: A role for epithelial-mesenchymal transition?
    • Thompson E. W., Newgreen D. F., Tarin D., Carcinoma invasion and metastasis: a role for epithelial-mesenchymal transition? Cancer Research 2005 65 14 5991 5995 (Pubitemid 40994377)
    • (2005) Cancer Research , vol.65 , Issue.14 , pp. 5991-5995
    • Thompson, E.W.1    Newgreen, D.F.2
  • 80
    • 77952855239 scopus 로고    scopus 로고
    • Epithelial mesenchymal transition and cancer stem cell-like phenotypes facilitate chemoresistance in recurrent ovarian cancer
    • Ahmed N., Abubaker K., Findlay J., Quinn M., Epithelial mesenchymal transition and cancer stem cell-like phenotypes facilitate chemoresistance in recurrent ovarian cancer Current Cancer Drug Targets 2010 10 3 268 278
    • (2010) Current Cancer Drug Targets , vol.10 , Issue.3 , pp. 268-278
    • Ahmed, N.1    Abubaker, K.2    Findlay, J.3    Quinn, M.4
  • 81
    • 84856751507 scopus 로고    scopus 로고
    • The biphasic nature of hypoxia-induced directional migration of activated human hepatic stellate cells
    • Novo E., Povero D., Busletta C., The biphasic nature of hypoxia-induced directional migration of activated human hepatic stellate cells The Journal of Pathology 2011 226 4 588 597
    • (2011) The Journal of Pathology , vol.226 , Issue.4 , pp. 588-597
    • Novo, E.1    Povero, D.2    Busletta, C.3
  • 82
    • 79955497173 scopus 로고    scopus 로고
    • Phosphoglucose isomerase/autocrine motility factor mediates epithelial-mesenchymal transition regulated by miR-200 in breast cancer cells
    • Ahmad A., Aboukameel A., Kong D., Wang Z., Sethi S., Chen W., Sarkar F. H., Raz A., Phosphoglucose isomerase/autocrine motility factor mediates epithelial-mesenchymal transition regulated by miR-200 in breast cancer cells Cancer Research 2011 71 9 3400 3409
    • (2011) Cancer Research , vol.71 , Issue.9 , pp. 3400-3409
    • Ahmad, A.1    Aboukameel, A.2    Kong, D.3    Wang, Z.4    Sethi, S.5    Chen, W.6    Sarkar, F.H.7    Raz, A.8
  • 84
    • 84856111309 scopus 로고    scopus 로고
    • MiR-141 and miR-200a act on ovarian tumorigenesis by controlling oxidative stress response
    • Mateescu B., Batista L., Cardon M., miR-141 and miR-200a act on ovarian tumorigenesis by controlling oxidative stress response Nature Medicine 2011 17 1627 1635
    • (2011) Nature Medicine , vol.17 , pp. 1627-1635
    • Mateescu, B.1    Batista, L.2    Cardon, M.3
  • 87
    • 77953560003 scopus 로고    scopus 로고
    • Loss of stromal caveolin-1 leads to oxidative stress, mimics hypoxia and drives inflammation in the tumor microenvironment, conferring the reverse warburg effect: A transcriptional informatics analysis with validation
    • Pavlides S., Tsirigos A., Vera I., Flomenberg N., Frank P. G., Casimiro M. C., Wang C., Fortina P., Addya S., Pestell R. G., Martinez-Outschoorn U. E., Sotgia F., Lisanti M. P., Loss of stromal caveolin-1 leads to oxidative stress, mimics hypoxia and drives inflammation in the tumor microenvironment, conferring the reverse warburg effect: a transcriptional informatics analysis with validation Cell Cycle 2010 9 11 2201 2219
    • (2010) Cell Cycle , vol.9 , Issue.11 , pp. 2201-2219
    • Pavlides, S.1    Tsirigos, A.2    Vera, I.3    Flomenberg, N.4    Frank, P.G.5    Casimiro, M.C.6    Wang, C.7    Fortina, P.8    Addya, S.9    Pestell, R.G.10    Martinez-Outschoorn, U.E.11    Sotgia, F.12    Lisanti, M.P.13
  • 88
    • 84055225365 scopus 로고    scopus 로고
    • Warburg meets autophagy: Cancer-associated fibroblasts accelerate tumor growth and metastasis via oxidative stress, mitophagy, and aerobic glycolysis
    • Pavlides S., Vera I., Gandara R., Warburg meets autophagy: cancer-associated fibroblasts accelerate tumor growth and metastasis via oxidative stress, mitophagy, and aerobic glycolysis Antioxidants Redox Signaling 2012 16 11 1264 1284
    • (2012) Antioxidants Redox Signaling , vol.16 , Issue.11 , pp. 1264-1284
    • Pavlides, S.1    Vera, I.2    Gandara, R.3
  • 89
    • 82755166890 scopus 로고    scopus 로고
    • Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to cellular antioxidant responses
    • Anastasiou D., Poulogiannis G., Asara J. M., Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to cellular antioxidant responses Science 2011 334 6060 1278 1283
    • (2011) Science , vol.334 , Issue.6060 , pp. 1278-1283
    • Anastasiou, D.1    Poulogiannis, G.2    Asara, J.M.3
  • 92
    • 79959819034 scopus 로고    scopus 로고
    • SirT3 suppresses hypoxia inducible factor 1 and tumor growth by inhibiting mitochondrial ROS production
    • Bell E. L., Emerling B. M., Ricoult S. J., Guarente L., SirT3 suppresses hypoxia inducible factor 1 and tumor growth by inhibiting mitochondrial ROS production Oncogene 2011 30 26 2986 2996
    • (2011) Oncogene , vol.30 , Issue.26 , pp. 2986-2996
    • Bell, E.L.1    Emerling, B.M.2    Ricoult, S.J.3    Guarente, L.4


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