Reactive oxygen species are required for maintenance and differentiation of primary lung fibroblasts in idiopathic pulmonary fibrosis

PLoS ONE

Volumn 5, Issue 11, 2010, Pages

  Bocchino, Marialuisa ^a   Agnese, Savina ^a   Fagone, Evelina ^b   Svegliati, Silvia ^c   Grieco, Domenico ^a   Vancheri, Carlo ^b   Gabrielli, Armando ^c   Sanduzzi, Alessandro ^a   Avvedimento, Enrico V ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b UNIVERSITY OF CATANIA   (Italy)

^c UNIVERSITÀ POLITECNICA DELLE MARCHE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN TYPE 1; PHOSPHOPROTEIN; PROTEIN TYROSINE KINASE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; ACETYLCYSTEINE; ACTIN; HYDROGEN PEROXIDE; MITOGEN ACTIVATED PROTEIN KINASE; OXIDIZING AGENT; SCAVENGER; TRANSFORMING GROWTH FACTOR BETA1;

ARTICLE; BIOLOGICAL TRAIT; CELL DEATH; CELL DIFFERENTIATION; CELL GROWTH; CELL LEVEL; CELL PROLIFERATION; CELL TYPE; CONTROLLED STUDY; ENZYME ACTIVATION; FIBROBLAST; FIBROBLAST CULTURE; FIBROSING ALVEOLITIS; HUMAN; HUMAN CELL; MOLECULAR DYNAMICS; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; PATHOGENESIS; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; CELL CULTURE; CELL SURVIVAL; CHEMISTRY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; METABOLISM; MIDDLE AGED; PATHOLOGY; PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SMOOTH MUSCLE; WESTERN BLOTTING;

ANIMALIA;

ACETYLCYSTEINE; ACTINS; BLOTTING, WESTERN; CELL DIFFERENTIATION; CELL SURVIVAL; CELLS, CULTURED; COLLAGEN TYPE I; DOSE-RESPONSE RELATIONSHIP, DRUG; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FIBROBLASTS; FREE RADICAL SCAVENGERS; HUMANS; HYDROGEN PEROXIDE; IDIOPATHIC PULMONARY FIBROSIS; MIDDLE AGED; MUSCLE, SMOOTH; OXIDANTS; PHOSPHORYLATION; PROTEIN-TYROSINE KINASES; REACTIVE OXYGEN SPECIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSFORMING GROWTH FACTOR BETA1;

EID: 78649502848     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0014003     Document Type: Article

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