Facilitated cellular uptake and suppression of inducible nitric oxide synthase by a metabolite of maritime pine bark extract (Pycnogenol)

Free Radical Biology and Medicine

Volumn 53, Issue 2, 2012, Pages 305-313

  Uhlenhut, Klaus ^a   Högger, Petra ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

EA.hy 926; Free radicals; Human monocytes; Inducible nitric oxide synthase; Nitric oxide; Phloretin; RAW 264.7 macrophages

Indexed keywords

DELTA (3,4 DIHYDROXYPHENYL) GAMMA VALEROLACTONE; DRUG METABOLITE; INDUCIBLE NITRIC OXIDE SYNTHASE; NITRIC OXIDE; NITRITE; PYCNOGENOL; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BLOOD SAMPLING; CELL TRANSPORT; CELL VIABILITY; CONTROLLED STUDY; DRUG UPTAKE; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MACROPHAGE; MONOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; BIOTRANSFORMATION; CATECHIN; CATECHOLS; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL CELLS; FACILITATED DIFFUSION; FLAVONOIDS; GENE EXPRESSION; HUMANS; MACROPHAGES; MICE; MONOCYTES; NITRIC OXIDE SYNTHASE TYPE II; NITRITES; PHLORETIN; PINUS; PLANT BARK; PLANT EXTRACTS;

PINUS PINASTER;

EID: 84862287505     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2012.04.013     Document Type: Article

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