Facilitative glucose transporter gene expression in human lymphocytes, monocytes, and macrophages: A role for GLUT isoforms 1, 3, and 5 in the immune response and foam cell formation

Blood Cells, Molecules, and Diseases

Volumn 32, Issue 1, 2004, Pages 182-190

  Fu, Yuchang ^a   Maianu, Lidia ^a   Melbert, Barry R ^a   Garvey, W Timothy ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

Cellular function; GLUT; Leukocytes

Indexed keywords

FRUCTOSE; GLUCOSE TRANSPORTER 1; GLUCOSE TRANSPORTER 3; GLUCOSE TRANSPORTER 5; MESSENGER RNA; PHYTOHEMAGGLUTININ;

ARTICLE; BINDING AFFINITY; CELL ACTIVATION; CELL ACTIVITY; CELL FUNCTION; CELL ISOLATION; CELL MATURATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; FOAM CELL; GENE EXPRESSION; GLUCOSE TRANSPORT SYSTEM; HUMAN; HUMAN CELL; IMMUNE RESPONSE; LYMPHOCYTE; MACROPHAGE; MONOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; REGULATORY MECHANISM;

EID: 0742289564     PISSN: 10799796     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcmd.2003.09.002     Document Type: Article

References (33)

1. Burant C.F., Sivitz W.I., Fukumoto H.et al. Mammalian glucose transporters: structure and molecular regulation. Recent Prog. Horm. Res. 47:1991;349-388.
2. Brant A.M., Gibbs E.M., Gould G.W., Thomas H.M. Immunological identification of five members of the human facilitative glucose transporter family. Biochem. Soc. Trans. 20:1992;236S.
3. Mueckler M. Facilitative glucose transporters. Eur. J. Biochem. 219:1994;713-725.
4. Garvey W.T., Birnbarm M.J. Cellular insulin action and insulin resistance. Baillière's Clin. Endocrinol. Metab. 7:1993;785-873.
5. Seatter M.J., Gould G.W. The mammalian facilitative glucose transporter (GLUT) family. Pharm. Biotechnol. 12:1999;201-228.
6. Hunter S.J., Garvey W.T. Insulin action and insulin resistance: diseases involving defects in insulin receptors, signal transduction, and the glucose transport effector system. Am. J. Med. 105:1998;331-345.
7. Ginsberg H.N. Insulin resistance and cardiovascular disease. J. Clin. Invest. 106:2000;453-458.
8. Liu Y.J., Saini A., Cohen D.J., Ooi B.S. Modulation of macrophage proliferation by hyperglycemia. Mol. Cell. Endocrinol. 114:1995;187-192.
9. Moser B., Loetscher P. Lymphocyte traffic control by chemokines. Nat. Immunol. 2:2001;123-128.
10. Luther S.A., Cyster J.G. Chemokines as regulators of T cell differentiation. Nat. Immunol. 2:2001;102-107.
11. Burger D. Cell contact-mediated signaling of monocytes by stimulated T cells: a major pathway for cytokine induction. Eur. Cytokine Network. 113:2000;346-353.
12. Auwerx J. The human leukemia cell line, THP-1: a multifaceted model for the study of monocyte-macrophage differentiation. Experientia. 47:1991;22-31.
13. Nagy L., Tontonoz P., Alvarez J.G.A., Chen H., Evans R.M. Oxidized LDL regulates macrophage gene expression through ligand activation of PPARγ Cell. 93:1998;229-240.
14. Tontonoz P., Nagy L., Alvarez J.G.A., Thomazy V.A., Evans R.M. PPARγ promotes monocyte/macrophage differentiation and uptake of oxidized LDL. Cell. 93:1998;241-252.
15. Steinberg D. Low density lipoprotein oxidation and its pathobiological significance. J. Biol. Chem. 272:1997;20963-20966.
16. Fu Y., Luo N., Lopes-Virella M.F. Oxidized LDL induces the expression of Adipocyte Lipid Binding Protein (ALBP/aP2) mRNA and protein in human THP-1 macrophages. J. Lipid Res. 41:2000;2017-2023.
17. Fu Y., Luo N., Lopes-Virella M.F. Upregulation of interleukin-8 expression by prostaglandin D2 metabolite 15-deoxy-delta12, 14 prostaglandin J2 (15d-PGJ2) in human THP-1 macrophages. Atherosclerosis. 160:2001;11-20.
18. Ross R. The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature. 362:1993;801-809.
19. Olson A.L., Pessin J.E. Structure, function, and regulation of the mammalian facilitative glucose transporter gene family. Annu. Rev. Nutr. 16:1996;235-256.
20. Palfreyman R.W., Clark A.E., Denton R.M., Holman G.D., Kozka I.J. Kinetic resolution of the separate GLUT1 and GLUT4 glucose transport activities in 3T3-L1 cells. Biochem. J. 284:1992;275-282.
21. Maher F., Davies-Hill T.M., Simpson I.A. Substrate specificity and kinetic parameters of GLUT3 in rat cerebellar granule neurons. Biochem. J. 315:1996;827-831.
22. Shepherd P.R., Gould G.W., Colville C.A., McCoid S.C., Gibbs E.M., Kahn B.B. Distribution of GLUT3 glucose transporter protein in human tissues. Biochem. Biophys. Res. Commun. 188:1992;149-154.
23. Maher F., Simpson I.A. The GLUT3 glucose transporter is the predominant isoform in primary cultured neurons: assessment by biosynthetic and photoaffinity labelling. Biochem. J. 301:1994;379-384.
24. Magnani P., Cherian P.V., Gould G.W., Greene D.A., Sima A.A., Brosius F.C. Glucose transporters in rat peripheral nerve: paranodal expression of GLUT1 and GLUT3. Metab., Clin. Exp. 45:1996;1466-1473.
25. Rumsey S.C., Kwon O., Xu G.W., Burant C.F., Simpson I., Levine M. Glucose transporter isoforms GLUT1 and GLUT3 transport dehydroascorbic acid. J. Biol. Chem. 272:1997;18982-18989.
26. Hiraki Y., Garcia de Herreros A., Birnbaum M.J. Transformation stimulates glucose transporter gene expression in the absence of protein kinase C. Proc. Natl. Acad. Sci. U. S. A. 86:1989;8252-8256.
27. Asano T., Shibasaki Y., Lin J.L.et al. Expression of the GLUT1 glucose transporter increases thymidine uptake in Chinese hamster ovary cells at low glucose concentrations. Cancer Res. 51:1991;4450-4454.
28. Farrell C.R., Boado R.J., Pardridge W.M. Enhanced GLUT1 glucose transporter and cytoskeleton gene expression in cultured bovine brain capillary endothelial cells after treatment with phorbol esters and serum. Brain Res. Mol. Brain Res. 15:1992;221-226.
29. Burant C.F., Takeda J., Brot-Laroche E., Bell G.I., Davidson N.O. Fructose transporter in human spermatozoa and small intestine is GLUT5. J. Biol. Chem. 267:1992;14523-14526.
30. Inukai K., Katagiri H., Takata K.et al. Characterization of rat GLUT5 and functional analysis of chimeric proteins of GLUT1 glucose transporter and GLUT5 fructose transporter. Endocrinology. 136:1995;4850-4857.
31. Kane S., Seatter M.J., Gould G.W. Functional studies of human GLUT5: effect of pH on substrate selection and an analysis of substrate interactions. Biochem. Biophys. Res. Commun. 238:1997;503-505.
32. Story J.A. Dietary carbohydrate and atherosclerosis. Fed. Proc. 41:1982;2797-2800.
33. Malide D., Devies-Hill T.M., Levine M., Simpson I.A. Distinct localization of GLUT-1, -3, and -5 in human monocyte-derived macrophages: effects of cell activation. Endocrinol. Metab. 274:1998;516-526.