Public health concern behind the exposure to persistent organic pollutants and the risk of metabolic diseases

BMC Public Health

Volumn 12, Issue 1, 2012, Pages

  Ruzzin, Jérôme ^a  

^a UNIVERSITY OF BERGEN   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; ORGANIC COMPOUND; PESTICIDE; POLYCHLORINATED BIPHENYL;

ANIMAL; ARTICLE; BLOOD; CATERING SERVICE; CATTLE; ENVIRONMENTAL EXPOSURE; EUROPEAN UNION; FEMALE; FOOD ANALYSIS; FOOD CONTAMINATION; GOVERNMENT REGULATION; HUMAN; ISOLATION AND PURIFICATION; LEGAL ASPECT; METABOLISM; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; POLLUTANT; RISK ASSESSMENT; SEA FOOD; STANDARD;

ANIMALS; CATTLE; DIABETES MELLITUS, TYPE 2; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL POLLUTANTS; EUROPEAN UNION; FEMALE; FOOD ANALYSIS; FOOD CONTAMINATION; FOOD SUPPLY; GLUCOSE; GOVERNMENT REGULATION; HUMANS; OBESITY; ORGANIC CHEMICALS; PESTICIDES; POLYCHLORINATED BIPHENYLS; RISK ASSESSMENT; SEAFOOD;

EID: 84862206428     PISSN: None     EISSN: 14712458     Source Type: Journal    
DOI: 10.1186/1471-2458-12-298     Document Type: Review

References (100)

1. National, regional, and global trends in body-mass index since 1980: systematic analysis of health examination surveys and epidemiological studies with 960 country-years and 9.1 million participants. Finucane MM, Stevens GA, Cowan MJ, Danaei G, Lin JK, Paciorek CJ, Singh GM, Gutierrez HR, Lu Y, Bahalim AN, et al. Lancet 2011 377 557 567 10.1016/S0140-6736(10)62037-5 21295846
2. National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2.7 million participants. Danaei G, Finucane MM, Lu Y, Singh GM, Cowan MJ, Paciorek CJ, Lin JK, Farzadfar F, Khang YH, Stevens GA, et al. Lancet 2011 378 31 40 10.1016/S0140-6736(11)60679-X 21705069
3. Economic Cooperation and Development, Health at a glance OECD Publishing, Europe 2010
4. Prevalence of overweight and obesity in the United States, 1999-2004. Ogden CL, Carroll MD, Curtin LR, McDowell MA, Tabak CJ, Flegal KM, JAMA 2006 295 1549 1555 10.1001/jama.295.13.1549 16595758
5. Prevalence of obesity and trends in body mass index among US children and adolescents, 1999-2010. Ogden CL, Carroll MD, Kit BK, Flegal KM, JAMA 2012 307 483 490 10.1001/jama.2012.40 22253364
6. American Diabetes Association, Diabetes Statistics. http://www.diabetes. org/diabetes-basics/diabetes-statistics
7. Center for Disease Control and Prevention, National Diabetes Fact Sheet, Data and Trends 2011
8. Health-economic burden of obesity in Europe. Muller-Riemenschneider F, Reinhold T, Berghofer A, Willich SN, Eur J Epidemiol 2008 23 499 509 10.1007/s10654-008-9239-1 18509729
9. Reconsidering metabolic diseases: the impacts of persistent organic pollutants. Ruzzin J, Lee DH, Carpenter DO, Jacobs DR, Atherosclerosis in press
10. Chemical toxins: a hypothesis to explain the global obesity epidemic. Baillie-Hamilton PF, J Alt Comp Med 2002 8 185 192 10.1089/107555302317371479 (Pubitemid 34438491)
11. Role of Environmental Chemicals in Diabetes and Obesity: A National Toxicology Program Workshop Report. Thayer KA, Heindel JJ, Bucher JR, Gallo MA, Environ Health Perspect in press
12. Obesogens: an environmental link to obesity. Holtcamp W, Environ Health Perspect 2012 120 62 A68 10.1289/ehp.120-a62 22296745
13. Most unwanted. Fisher BE, Environ Health Perspect 1999 107 18 A23 9872725
14. Global transport of organic pollutants-ambient concentrations in the remote marine atmosphere. Atlas E, Giam CS, Science 1981 211 163 165 10.1126/science.211.4478.163 17757266
15. Exposure to dioxin-like pollutants via different food commodities in Swedish children and young adults. Bergkvist C, Oberg M, Appelgren M, Becker W, Aune M, Ankarberg EH, Berglund M, Hakansson H, Food Chem Toxicol 2008 46 3360 3367 10.1016/j.fct.2008.07.029 18789370
16. Estimation of 1999-2004 dietary daily intake of PCDDs, PCDFs and dioxin-like PCBs by a total diet study in metropolitan Tokyo, Japan. Sasamoto T, Ushio F, Kikutani N, Saitoh Y, Yamaki Y, Hashimoto T, Horii S, Nakagawa JI, Ibe A, Chemosphere 2006 64 634 641 10.1016/j.chemosphere.2005.10.057 16376969 (Pubitemid 43929062)
17. Daily intake of polychlorinated dibenzo-p-dioxins/polychlorinated dibenzofurans (PCDD/PCDFs) in foodstuffs consumed in Tarragona, Spain: a review of recent studies (2001-2003) on human PCDD/PCDF exposure through the diet. Bocio A, Domingo JL, Environ Res 2005 97 1 9 10.1016/j.envres.2004.01.012 15476728 (Pubitemid 39336385)
18. Dietary exposures to food contaminants across the United States. Dougherty CP, Holtz SH, Reinert JC, Panyacosit L, Axelrad DA, Woodruff TJ, Environ Res 2000 84 170 185 10.1006/enrs.2000.4027 11068931
19. Perfluorinated compounds, polychlorinated biphenyls, and organochlorine pesticide contamination in composite food samples from Dallas, Texas, USA. Schecter A, Colacino J, Haffner D, Patel K, Opel M, Papke O, Birnbaum L, Environ Health Perspect 2010 118 796 802 10.1289/ehp.0901347 20146964
20. Dietary intake estimations of organohalogen contaminants (dioxins, PCB, PBDE and chlorinated pesticides, e.g. DDT) based on Swedish market basket data. Darnerud PO, Atuma S, Aune M, Bjerselius R, Glynn A, Grawe KP, Becker W, Food Chem Toxicol 2006 44 1597 1606 10.1016/j.fct.2006.03.011 16730400 (Pubitemid 43994268)
21. Dioxins, furans and dioxin-like PCBs: occurrence in food and dietary intake in France. Tard A, Gallotti S, Leblanc JC, Volatier JL, Food Addit Contam 2007 24 1007 1017 10.1080/02652030701317293 17691015 (Pubitemid 47263920)
22. Market basket study on dietary intake of PCDD/Fs, PCBs, and PBDEs in Finland. Kiviranta H, Ovaskainen MAL, Vartiainen T, Environ Int 2004 30 923 932 10.1016/j.envint.2004.03.002 15196840 (Pubitemid 38771989)
23. Current dietary exposure to polychlorodibenzo-p-dioxins, polychlorodibenzofurans, and dioxin-like polychlorobiphenyls in Italy. Fattore E, Fanelli R, Turrini A, di Domenico A, Mol Nutr Food Res 2006 50 915 921 10.1002/mnfr.200500212 17009212 (Pubitemid 44621796)
24. Intake of dioxins and related compounds from food in the US population. Schecter A, Cramer P, Boggess K, Stanley J, Papke O, Olson J, Silver A, Schmitz M, J Toxicol Env Health Pt A 2001 63 1 18 10.1080/152873901750128326 (Pubitemid 32391854)
25. Persistent toxic chemicals in the US food supply. Schafer KS, Kegley SE, J Epidemiol Comm Health 2002 56 813 817 10.1136/jech.56.11.813 (Pubitemid 35178136)
26. Estimation of dietary intake of PCB and organochlorine pesticides for children and adults. Fromberg A, Granby K, Hojgard A, Fagt S, Larsen JC, Food Chem 2011 125 1179 1187 10.1016/j.foodchem.2010.10.025
27. Increased risk of diabetes and polychlorinated biphenyls and dioxins-A 24-year follow-up study of the Yucheng cohort. Wang SL, Tsai PC, Yang CY, Guo YL, Diabetes Care 2008 31 1574 1579 10.2337/dc07-2449 18487481
28. Serum dioxin and diabetes mellitus in veterans of Operation Ranch Hand. Henriksen GL, Ketchum NS, Michalek JE, Swaby JA, Epidemiology 1997 8 252 258 10.1097/00001648-199705000-00005 9115019 (Pubitemid 27183689)
29. A strong dose-response relation between serum concentrations of persistent organic pollutants and diabetes: results from the National Health and Examination Survey 1999-2002. Lee DH, Lee IK, Song K, Steffes M, Toscano W, Baker BA, Jacobs DR, Diabetes Care 2006 29 1638 1644 10.2337/dc06-0543 16801591 (Pubitemid 44127593)
30. Exposure to persistent organochlorine pollutants and type 2 diabetes mellitus. Rignell-Hydbom A, Rylander L, Hagmar L, Hum Exp Toxicol 2007 26 447 452 10.1177/0960327107076886 17623770 (Pubitemid 47057004)
31. Dioxin/polychlorinated biphenyl body burden, diabetes and endometriosis: findings in a population-based study in Belgium. Fierens S, Mairesse H, Heilier JF, De Burbure C, Focant JF, Eppe G, De Pauw E, Bernard A, Biomarkers 2003 8 529 534 10.1080/1354750032000158420 15195683 (Pubitemid 38418283)
32. Prevalence of diabetes and body burdens of polychlorinated biphenyls, polybrominated diphenyl ethers, and p, p'-diphenyldichloroethene in Great Lakes sport fish consumers. Turyk M, Anderson HA, Knobeloch L, Imm P, Persky VW, Chemosphere 2009 75 674 679 10.1016/j.chemosphere.2008.12.035 19157498
33. Exposure to p, p '-DDE: A Risk Factor for Type 2 Diabetes. Rignell-Hydbom A, Lidfeldt J, Kiviranta H, Rantakokko P, Samsioe G, Agardh CD, Rylander L, PLoS One 2009 4 10 7503 10.1371/journal.pone.0007503 19838294
34. High prevalence of prediabetes and diabetes in a population exposed to high levels of an organochlorine cocktail. Ukropec J, Radikova Z, Huckova M, Koska J, Kocan A, Sebokova E, Drobna B, Trnovec T, Susienkova K, Labudova V, et al. Diabetologia 2010 53 899 906 10.1007/s00125-010-1683-2 20182860
35. Diabetes an relation to serum levels of polychlorinated biphenyls and chlorinated pesticides an adult native Americans. Codru N, Schymura MJ, Negoita S, Rej R, Carpenter DO, Environ Health Perspect 2007 115 1442 1447 17938733 (Pubitemid 47618086)
36. Strong associations between low-dose organochlorine pesticides and type 2 diabetes in Korea. Son HK, Kim SA, Kang JH, Chang YS, Park SK, Lee SK, Jacobs DR, Lee DH, Environ Int 2010 36 410 414 10.1016/j.envint.2010.02.012 20381150
37. Association Between Type 2 Diabetes and Exposure to Persistent Organic Pollutants. Airaksinen R, Rantakokko P, Eriksson JG, Blomstedt P, Kajantie E, Kiviranta H, Diabetes Care 2011 34 1972 1979 10.2337/dc10-2303 21816981
38. Polychlorinated Biphenyl (PCB) Exposure and Diabetes: Results from the Anniston Community Health Survey. Silverstone AE, Rosenbaum PF, Weinstock RS, Bartell SM, Foushee HR, Shelton C, Pavuk M, Environ Health Perspect in press
39. Polychlorinated biphenyls and organochlorine pesticides in plasma predict development of type 2 diabetes in the elderly: the prospective investigation of the vasculature in uppsala seniors (PIVUS) study. Lee DH, Lind M, Jacobs DR, Sahlihovic S, van Bavel B, Lind L, Diabetes Care 2011 34 1 7 10.2337/dc10-1990
40. Polychlorinated biphenyls, lead, and mercury are associated with liver disease in American adults: NHANES 2003-2004. Cave M, Appana S, Patel M, Falkner KC, McClain CJ, Brock G, Environ Health Perspect 2010 118 1735 1742 10.1289/ehp.1002720 21126940
41. Blood pressure in relation to concentrations of PCB congeners and chlorinated pesticides. Goncharov A, Pavuk M, Foushee HR, Carpenter DO, Environ Health Perspect 2011 119 319 325 21362590
42. Low dose of some persistent organic pollutants predicts type 2 diabetes: a nested case-control study. Lee DH, Steffes MW, Sjodin A, Jones RS, Needham LL, Jacobs DR, Environ Health Perspect 2010 118 1235 1242 10.1289/ehp.0901480 20444671
43. Organochlorine exposure and incidence of diabetes in a cohort of Great Lakes sport fish consumers. Turyk M, Anderson H, Knobeloch L, Imm P, Persky V, Environ Health Perspect 2009 117 1076 1082 19654916
44. Persistent organic pollutant exposure leads to insulin resistance syndrome. Ruzzin J, Petersen R, Meugnier E, Madsen L, Lock EJ, Lillefosse H, Ma T, Pesenti S, Du ZY, Chavey C, et al. Environ Health Perspect 2010 118 465 471 20064776
45. Chronic consumption of farmed salmon containing persistent organic pollutants causes insulin resistance and obesity in mice. Ibrahim MM, Fjaere E, Lock EJ, Naville D, Amlund H, Meugnier E, Le Magueresse Battistoni B, Froyland L, Madsen L, Jessen N, et al. PLoS One 2011 6 9 25170 10.1371/journal.pone. 0025170 21966444
46. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and 1,2,3,4,7,8- hexachlorodibenzo-p-dioxin (HxCDD) alter body weight by decreasing insulin-like growth factor I (IGF-I) signaling. Croutch CR, Lebofsky M, Schramm KW, Terranova PF, Rozman KK, Toxicol Sci 2005 85 560 571 10.1093/toxsci/kfi106 15703265 (Pubitemid 40614285)
47. NTP Toxicology and Carcinogenesis Studies of a Binary Mixture of 3,3',4,4',5-Pentachlorobiphenyl (PCB 126) (CAS No. 57465-28-8) and 2,2',4,4',5,5'-Hexachlorobiphenyl (PCB 153) (CAS No. 35065-27-1) in Female Harlan Sprague-Dawley Rats (Gavage Studies). National Toxicology Program, Natl Toxicol Program Tech Rep Ser 2006 1 258 22692228
48. Polychlorinated biphenyl-77 induces adipocyte differentiation and proinflammatory adipokines and promotes obesity and atherosclerosis. Arsenescu V, Arsenescu RI, King V, Swanson H, Cassis LA, Environ Health Perspect 2008 116 761 768 10.1289/ehp.10554 18560532 (Pubitemid 351943932)
49. Endocrine disrupters as obesogens. Grun F, Blumberg B, Mol Cell Endo 2009 304 19 29 10.1016/j.mce.2009.02.018
50. Stockholm Convention, http://chm.pops.int
51. Aldrin and Dieldrin: a review of research on their production, environmental deposition and fate, bioaccumulation, toxicology and epidemiology in the United States. Jorgenson JL, Environ Health Perspect 2001 109 113 139 11250811 (Pubitemid 32327907)
52. WHO, The use of DDT in malaria vector control, 2007
53. Malaria control insecticide residues in breast milk: the need to consider infant health risks. Bouwman H, Kylin H, Environ Health Perspect 2009 117 1477 1480 20019894
54. DDT and malaria prevention: addressing the paradox. Bouwman H, van den Berg H, Kylin H, Environ Health Perspect 2011 119 744 747 10.1289/ehp.1002127 21245017
55. DDT Paradox. Tren R, Roberts D, Environ Health Perspect 2011 119 423 A424 21968389
56. Global status of DDT and its alternatives for use in vector control to prevent disease. van den Berg H, Environ Health Perspect 2009 117 1656 1663 10.1289/ehp.0900785 20049114
57. Toxic equivalency factors (TEFs) for PCBs, PCDDs, PCDFs for humans and wildlife. Van Den Berg M, Birnbaum L, Bosveld ATC, Brunstrom B, Cook P, Feeley M, Giesy JP, Hanberg A, Hasegawa R, Kennedy SW, et al. Environ Health Perspect 1998 106 775 792 10.1289/ehp.98106775 9831538 (Pubitemid 29073822)
58. The 2005 World Health Organization reevaluation of human and Mammalian toxic equivalency factors for dioxins and dioxin-like compounds. Van Den Berg M, Birnbaum LS, Denison M, De Vito M, Farland W, Feeley M, Fiedler H, Hakansson H, Hanberg A, Haws L, et al. Toxicol Sci 2006 93 223 241 10.1093/toxsci/kfl055 16829543 (Pubitemid 44400442)
59. Dioxins, dioxin-like PCBs and non-dioxin-like PCBs in foodstuffs: occurrence and dietary intake in The Netherlands. Baars AJ, Bakker MI, Baumann RA, Boon PE, Freijer JI, Hoogenboom LAP, Hoogerbrugge R, van Klaveren JD, Liem AKD, Traag WA, et al. Toxicol Lett 2004 151 51 61 10.1016/j.toxlet.2004.01.028 15177640 (Pubitemid 38739027)
60. Significant decreasing trend in human dietary exposure to PCDD/PCDFs and PCBs in Catalonia, Spain. Llobet JM, Marti-Cid R, Castell V, Domingo JL, Toxicol Lett 2008 178 117 126 10.1016/j.toxlet.2008.02.012 18406548
61. Temporal trends in serum concentrations of polychlorinated dioxins, furans, and PCBs among adult women living in Chapaevsk, Russia: a longitudinal study from 2000 to 2009. Humblet O, Sergeyev O, Altshul L, Korrick SA, Williams PL, Emond C, Birnbaum LS, Burns JS, Lee MM, Revich B, et al. Environ Health 2011 10 62 10.1186/1476-069X-10-62 21696632
62. The environmental specimen bank for human tissues as part of the German environmental specimen bank. Wiesmuller GA, Eckard R, Dobler L, Gunsel A, Oganowski M, Schroter-Kermani C, Schluter C, Gies A, Kemper FH, Int J Hyg Environ Health 2007 210 299 305 10.1016/j.ijheh.2007.01.036 17369091 (Pubitemid 46618120)
63. Perspective on serum dioxin levels in the United States: an evaluation of the NHANES data. LaKind JS, Hays SM, Aylward LL, Naiman DQ, J Expo Sci Environ Epidemiol 2009 19 435 441 10.1038/jes.2008.63 18854873
64. A longitudinal study of trends in blood dioxins and dioxin-like compounds levels in residents from two locations in Japan during 2002-2006. Furuya H, Kayama F, Hasegawa M, Nagai M, Suzuki T, Arch Environ Contam Toxicol 2010 58 892 900 10.1007/s00244-009-9437-1 20035326
65. Polybrominated diphenyl ethers (PBDE) in blood of children in Baden-Wurttemberg between 2002/03 and 2008/09. Link B, Gabrio T, Mann V, Schilling B, Maisner V, Konig M, Flicker-Klein A, Zollner I, Fischer G, Int J Hyg Environ Health 2012 215 224 228 10.1016/j.ijheh.2011.10.018 22192581
66. Temporal changes in the levels of perfluorinated compounds in California women's serum over the past 50 years. Wang M, Park JS, Petreas M, Environ Sci Technol 2011 45 7510 7516 21732675
67. Trends in exposure to polyfluoroalkyl chemicals in the U.S. Population: 1999-2008. Kato K, Wong LY, Jia LT, Kuklenyik Z, Calafat AM, Environ Sci Technol 2011 45 8037 8045 10.1021/es1043613 21469664
68. European Commission, Opinion of the SCF on the risk assessment of dioxins and dioxin-like PCBs in food, 2000
69. Risk assessment of dioxins and dioxin-like PCBs in food-Comments by the German Federal Environmental Agency. Gies A, Neumeier G, Rappolder M, Konietzka R, Chemosphere 2007 67 344 S349 10.1016/j.chemosphere.2006.05.128 17223171 (Pubitemid 46367169)
70. European Commission, Opinion of the SCF on the risk assessment of dioxins and dioxin-like PCBs in food. Up-date based on new scientific information, 2001
71. Concentrations of PCDD/PCDFs and PCBs in fish and seafood from the Catalan (Spain) market: Estimated human intake. Bocio A, Domingo JL, Falco G, Llobet JM, Environ Int 2007 33 170 175 10.1016/j.envint.2006.09.005 17049987 (Pubitemid 44960464)
72. Exposure of populations to dioxins and related compounds. Liem AKD, Furst P, Rappe C, Food Add Cont 2000 17 241 259 10.1080/026520300283324 (Pubitemid 30410583)
73. Large effects from small exposures. I. Mechanisms for endocrine-disrupting chemicals with estrogenic activity. Welshons WV, Thayer KA, Judy BM, Taylor JA, Curran EM, Vom Saal FS, Environ Health Perspect 2003 111 994 1006 10.1289/ehp.5494 12826473 (Pubitemid 36826881)
74. Nonmonotonic dose-response relationships: mechanistic basis, kinetic modeling, and implications for risk assessment. Conolly RB, Lutz WK, Toxicol Sci 2004 77 151 157 14600281 (Pubitemid 38128655)
75. Could low-level background exposure to persistent organic pollutants contribute to the social burden of type 2 diabetes? Lee DH, Jacobs DR, Porta M, J Epi Com Health 2006 60 1006 1008 10.1136/jech.2006.053389 (Pubitemid 44861851)
76. Associations of persistent organic pollutants with abdominal obesity in the elderly: The Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS) study. Lee DH, Lind L, Jacobs DR, Salihovic S, van Bavel B, Lind PM, Environ Int 2011 40 170 178 21835469
77. Low dose organochlorine pesticides and polychlorinated biphenyls predict obesity, dyslipidemia, and insulin resistance among people free of diabetes. Lee DH, Steffes MW, Sjodin A, Jones RS, Needham LL, Jacobs DR, PLoS One 2011 6 1 15977 10.1371/journal.pone.0015977 21298090
78. Polychlorinated Biphenyls and Organochlorine Pesticides in Plasma Predict Development of Type 2 Diabetes in the Elderly: The Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS) Study. Lee DH, Lind PM, Jacobs DR, Salihovic S, van Bavel B, Lind L, Diabetes Care 2011 34 1778 1784 10.2337/dc10-2116 21700918
79. Mechanistic basis for elevation in risk of diabetes caused by persistent organic pollutants. Ruzzin J, Effects of persistent and bioactive organic pollutants on human health John Wiley & Sons, Inc, Carpenter DO, in press
80. Endocrine disruptors: from endocrine to metabolic disruption. Casals-Casas C, Desvergne B, Annu Rev Physiol 2011 73 135 162 10.1146/annurev-physiol-012110-142200 21054169
81. Exposure of breast-fed children in the Czech Republic to PCDDs, PCDFs, and dioxin-like PCBs. Bencko V, Cerna M, Jech L, Smid J, Environ Toxicol Pharmacol 2004 18 83 90 10.1016/j.etap.2004.01.009 21782737 (Pubitemid 39471609)
82. Levels and profiles of PCDDs, PCDFs and cPCBs in Belgian breast milk. Focant JF, Pirard C, Thielen C, De Pauw E, Estimation of infant intake. Chemosphere 2002 48 763 770 (Pubitemid 34857471)
83. Dioxins, polychlorinated biphenyls and other organohalogen compounds in human milk-Levels, correlations, trends and exposure through breastfeeding. Furst P, Mol Nutr Food Res 2006 50 922 933 10.1002/mnfr.200600008 17009213 (Pubitemid 44621797)
84. A comparison of PCDD/PCDFs exposure in infants via formula milk or breast milk feeding. Hsu JF, Guo YL, Liu CH, Hu SC, Wang JN, Liao PC, Chemosphere 2007 66 311 319 10.1016/j.chemosphere.2006.04.089 16777183 (Pubitemid 44791400)
85. Dietary exposure to polychlorinated biphenyls and dioxins from infancy until adulthood: A comparison between breast-feeding, toddler, and longterm exposure. Patandin S, Dagnelie PC, Mulder PGH, de Coul EO, van der Veen JE, Weisglas-Kuperus N, Sauer PJJ, Environ Health Perspect 1999 107 45 51 10.1289/ehp.9910745 9872716 (Pubitemid 29095084)
86. Dietary intake of PCDD/F by small children with different food consumption measured by the duplicate method. Wittsiepe J, Schrey P, Wilhelm M, Chemosphere 2001 43 881 887 10.1016/S0045-6535(00)00448-3 11372880 (Pubitemid 32405544)
87. Dioxin and dioxin-like PCB exposure of non-breastfed Dutch infants. Weijs PJM, Bakker MI, Korver KR, Ghanaviztchi KV, van Wijnen JH, Chemosphere 2006 64 1521 1525 10.1016/j.chemosphere.2005.12.022 16442144 (Pubitemid 44066512)
88. How are children different from adults. Bearer CF, Environ Health Perspect 1995 103 7 12 8635442
89. Epigenetic transgenerational actions of endocrine disruptors and mate fertility. Anway MD, Cupp AS, Uzumcu M, Skinner MK, Science 2005 308 1466 1469 10.1126/science.1108190 15933200 (Pubitemid 40791300)
90. Global assessment of organic contaminants in farmed salmon. Hites RA, Foran JA, Carpenter DO, Hamilton MC, Knuth BA, Schwager SJ, Science 2004 303 226 229 10.1126/science.1091447 14716013 (Pubitemid 38057571)
91. Separation of risks and benefits of seafood intake. Budtz-Jorgensen E, Grandjean P, Weihe P, Environ Health Perspect 2007 115 323 327 17431478 (Pubitemid 46554428)
92. Benefits versus risks associated with consumption of fish and other seafood. Bushkin-Bedient S, Carpenter DO, Rev Environ Health 2010 25 161 191 21038755
93. Amending regulation (EC) No 466/2001 setting maximum levels for certain contaminants in foodstuffs as regards dioxins and dioxin-like PCBs. Commission Regulation, Official Journal of the European Union 2006 No 199/2006
94. Associations of serum concentrations of organochlorine pesticides with breast cancer and prostate cancer in US adults. Xu XH, Dailey AB, Talbott EO, Ilacqua VA, Kearney G, Asal NR, Environ Health Perspect 2010 118 60 66 20056587
95. Elevated serum pesticide levels and risk of Parkinson disease. Richardson JR, Shalat SL, Buckley B, Winnik B, O'Suilleabhain P, Diaz-Arrastia R, Reisch J, German DC, Arch Neurol 2009 66 870 875 10.1001/archneurol.2009.89 19597089
96. Amending regulation (EC) No 396/2005 on maximum residue levels of pesticides in or on food and feed of plant and animal origin, as regards the implementing powers conferred on the commission. Commission Regulation, Official Journal of the European Union 2008 No 299/2008
97. Dietary omega-3 fatty acids and fish consumption and risk of type 2 diabetes. Djousse L, Gaziano JM, Buring JE, Lee IM, Am J Clin Nutr 2011 93 143 150 10.3945/ajcn.110.005603 20980491
98. Long-chain omega-3 fatty acids, fish intake, and the risk of type 2 diabetes mellitus. Kaushik M, Mozaffarian D, Spiegelman D, Manson JE, Willett WC, Hu FB, Am J Clin Nutr 2009 90 613 620 10.3945/ajcn.2008.27424 19625683
99. Association between type of dietary fish and seafood intake and the risk of incident type 2 diabetes the European prospective investigation of cancer (EPIC)-Norfolk cohort study. Patel PS, Bingham SA, Sharp SJ, Wareham NJ, Luben RN, Forouhi NG, Khaw KT, Diabetes Care 2009 32 1857 1863 10.2337/dc09-0116 19592633
100. The Role of persistent organic pollutants in the worldwide epidemic of type 2 diabetes mellitus and the possible connection to farmed Atlantic Salmon (Salmo salar). Crinnion WJ, Alter Med Review 2012 16 301 313