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Volumn 67, Issue 9, 2007, Pages

Risk assessment of dioxins and dioxin-like PCBs in food - Comments by the German Federal Environmental Agency

Author keywords

Dioxin like PCBs; Polychlorinated dibenzo p dioxins and dibenzofurans; Protection of vulnerable groups; Risk assessment; Tolerable daily intake; Uncertainty

Indexed keywords

ENVIRONMENTAL IMPACT; HEALTH RISKS; POLYCHLORINATED BIPHENYLS; RISK ASSESSMENT;

EID: 33847689009     PISSN: 00456535     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chemosphere.2006.05.128     Document Type: Article
Times cited : (35)

References (45)
  • 1
    • 0029992585 scopus 로고    scopus 로고
    • Intake, fecal excretion and body burden of polychlorinated dibenzo-p-dioxins and dibenzofurans in breast-fed and for-mula-fed infants
    • Abraham K., Knoll A., Ende M., et al. Intake, fecal excretion and body burden of polychlorinated dibenzo-p-dioxins and dibenzofurans in breast-fed and for-mula-fed infants. Pedriatr. Res. 40 5 (1996) 671-679
    • (1996) Pedriatr. Res. , vol.40 , Issue.5 , pp. 671-679
    • Abraham, K.1    Knoll, A.2    Ende, M.3
  • 2
    • 0032190741 scopus 로고    scopus 로고
    • Time course of PCDD/PCDF/PCB concentrations in breast-feeding mothers and their infants
    • Abraham K., Päpke O., Gross A., et al. Time course of PCDD/PCDF/PCB concentrations in breast-feeding mothers and their infants. Chemosphere 37 9-12 (1998) 1731-1741
    • (1998) Chemosphere , vol.37 , Issue.9-12 , pp. 1731-1741
    • Abraham, K.1    Päpke, O.2    Gross, A.3
  • 3
    • 19944434228 scopus 로고    scopus 로고
    • Concentration-dependent TCDD elimination kinetics in humans: toxicokinetic modeling for moderately to highly exposed adults from Seveso, Italy, and Vienna, Austria, and impact on dose estimates for the NIOSH cohort
    • Aylward L.L., Brunet R.C., Carrier G.T., et al. Concentration-dependent TCDD elimination kinetics in humans: toxicokinetic modeling for moderately to highly exposed adults from Seveso, Italy, and Vienna, Austria, and impact on dose estimates for the NIOSH cohort. J. Expos. Anal. Environ. Epidemiol. 15 (2005) 51-65
    • (2005) J. Expos. Anal. Environ. Epidemiol. , vol.15 , pp. 51-65
    • Aylward, L.L.1    Brunet, R.C.2    Carrier, G.T.3
  • 4
    • 0024348209 scopus 로고
    • Behavioral effects in monkeys exposed to 2,3,7,8-TCDD transmitted maternally during gestation and for four months nursing
    • Bowman R.E., Schantz S.L., Gross M.L., et al. Behavioral effects in monkeys exposed to 2,3,7,8-TCDD transmitted maternally during gestation and for four months nursing. Chemosphere 18 (1989) 235-242
    • (1989) Chemosphere , vol.18 , pp. 235-242
    • Bowman, R.E.1    Schantz, S.L.2    Gross, M.L.3
  • 5
    • 32044471070 scopus 로고    scopus 로고
    • Is fish oil good or bad for heart disease? Two trials with apparently conflicting results
    • Burr M.L., Dunstan F.D., and George C.H. Is fish oil good or bad for heart disease? Two trials with apparently conflicting results. J. Membr. Biol. 206 2 (2005) 155-163
    • (2005) J. Membr. Biol. , vol.206 , Issue.2 , pp. 155-163
    • Burr, M.L.1    Dunstan, F.D.2    George, C.H.3
  • 6
    • 33847660491 scopus 로고    scopus 로고
    • Commission of the European Communities 2000. Communication from the Commission on the Precautionary Principle, COM (2000) 1, adapted 2.2.2000 http://europa.eu.int/comm/dgs/health_consumer/library/pub/pub07_en.pdf.
  • 7
    • 33847690268 scopus 로고    scopus 로고
    • Commission of the European Communities 2001. Council Regulation (EC) No 2375/2001 of 29 November 2001.
  • 8
    • 33847649604 scopus 로고    scopus 로고
    • EEC, 1967. Council Directive 1967/548/EEC of 27 June 1967on the approximation of laws, regulations and administrative provisions relating to the classification, packaging and labelling of dangerous substances, Official Journal B 196, 16.08.1967, http://europa.eu.int/scadplus/leg/en/lvb/l21276.htm.
  • 9
    • 33847668847 scopus 로고    scopus 로고
    • EFSA Scientific Colloquium 2004. Dioxins, methodologies and principles for setting tolerable intake levels for dioxins, furans and dioxin-like PCBs. Summary Report, 28.-29. June 2004, Brussels, European Food Safety Authority, December 2004, ISBN 92-9199-000-0, p. 130.
  • 10
    • 33847685901 scopus 로고    scopus 로고
    • EPA, 2000. Exposure and Human Health Reassessment of 2,3,7,8-tetra-chlorodibenzo-p-Dioxin (TCDD) and Related Compounds, Draft Final, US Environmental Protection Agency, Washington, DC, Draft www.epa.gov/ncea.
  • 11
    • 0032103386 scopus 로고    scopus 로고
    • Reproductive toxicity and tissue concentrations of low doses of 2,3,7,8-tetrachlorodibenzo-p-dioxin in male offspring rats exposed throughout pregnancy and lactation
    • Faqi A.S., Dalsenter P.R., Merker H.-J., and Chahoud I. Reproductive toxicity and tissue concentrations of low doses of 2,3,7,8-tetrachlorodibenzo-p-dioxin in male offspring rats exposed throughout pregnancy and lactation. Toxicol. Appl. Pharmacol. 150 (1998) 383-392
    • (1998) Toxicol. Appl. Pharmacol. , vol.150 , pp. 383-392
    • Faqi, A.S.1    Dalsenter, P.R.2    Merker, H.-J.3    Chahoud, I.4
  • 12
    • 0029940875 scopus 로고    scopus 로고
    • Elimination of polychlorinated dibenzo-p-dioxins dibenzofurans on occupationally exposed persons
    • Flesch-Janys D., Belcher H., Gurn P., et al. Elimination of polychlorinated dibenzo-p-dioxins dibenzofurans on occupationally exposed persons. J. Toxicol. Environ. Health 47 (1996) 363-378
    • (1996) J. Toxicol. Environ. Health , vol.47 , pp. 363-378
    • Flesch-Janys, D.1    Belcher, H.2    Gurn, P.3
  • 13
    • 0034956790 scopus 로고    scopus 로고
    • Early indicators of response in biologically based risk assessment for nongenotoxic carcinogens
    • Gastel J.A. Early indicators of response in biologically based risk assessment for nongenotoxic carcinogens. Regul. Toxicol. Pharmacol. 33 (2001) 393-398
    • (2001) Regul. Toxicol. Pharmacol. , vol.33 , pp. 393-398
    • Gastel, J.A.1
  • 14
    • 0033019907 scopus 로고    scopus 로고
    • Persistent suppression of delayed-type hypersensitivity (DTH) in rats perinatally exposed to TCDD
    • Gehrs B.C., and Smialowicz R.J. Persistent suppression of delayed-type hypersensitivity (DTH) in rats perinatally exposed to TCDD. Toxicology 134 (1999) 79-88
    • (1999) Toxicology , vol.134 , pp. 79-88
    • Gehrs, B.C.1    Smialowicz, R.J.2
  • 15
    • 0030847732 scopus 로고    scopus 로고
    • Persistent suppression of delayed-type hypersensitivity (DTH) in rats perinatally exposed to TCDD
    • Gehrs B.C., Riddle M.M., Williams W.C., et al. Persistent suppression of delayed-type hypersensitivity (DTH) in rats perinatally exposed to TCDD. Toxicology 122 (1997) 229-240
    • (1997) Toxicology , vol.122 , pp. 229-240
    • Gehrs, B.C.1    Riddle, M.M.2    Williams, W.C.3
  • 16
    • 0342601484 scopus 로고    scopus 로고
    • A dose-response analysis of the reproductive effects of a single gestational dose of 2,3,7,8-tetrachlorodibenzo-p-dioxin in male Long Evans hooded rat offspring
    • Gray Jr. L.E., Ostby J.S., and Kelce W.R. A dose-response analysis of the reproductive effects of a single gestational dose of 2,3,7,8-tetrachlorodibenzo-p-dioxin in male Long Evans hooded rat offspring. Toxicol. Appl. Pharmacol. 146 (1997) 11-20
    • (1997) Toxicol. Appl. Pharmacol. , vol.146 , pp. 11-20
    • Gray Jr., L.E.1    Ostby, J.S.2    Kelce, W.R.3
  • 17
    • 33847669309 scopus 로고    scopus 로고
    • Health Council of the Netherlands: Dioxins 1996. Advisory report no. 1996/10E, Rijswijk, 6 August 1996.
  • 18
    • 33847670522 scopus 로고    scopus 로고
    • On the role of ex post uncertainty assessment for risk management
    • Heinzl H., Mittlboeck M., and Edler L. On the role of ex post uncertainty assessment for risk management. Int. J. Risk Assess. Manage. 5 (2005) 206-215
    • (2005) Int. J. Risk Assess. Manage. , vol.5 , pp. 206-215
    • Heinzl, H.1    Mittlboeck, M.2    Edler, L.3
  • 19
    • 0028950362 scopus 로고
    • Perinatal exposure to polychlorinated biphenyls and dioxins and its effect on neonatal neurological development
    • Huisman M., Koopman-Esseboom C., Fidler V., et al. Perinatal exposure to polychlorinated biphenyls and dioxins and its effect on neonatal neurological development. Early Hum. Dev. 41 (1995) 111-127
    • (1995) Early Hum. Dev. , vol.41 , pp. 111-127
    • Huisman, M.1    Koopman-Esseboom, C.2    Fidler, V.3
  • 20
    • 0033952518 scopus 로고    scopus 로고
    • Acute administration of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in pregnant Long Evans rats: association of measured tissue concentration with developmental effects
    • Hurst C.H., De Vito M.J., Setzer R.W., et al. Acute administration of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in pregnant Long Evans rats: association of measured tissue concentration with developmental effects. Toxicol. Sci. 53 (2000) 411-420
    • (2000) Toxicol. Sci. , vol.53 , pp. 411-420
    • Hurst, C.H.1    De Vito, M.J.2    Setzer, R.W.3
  • 21
    • 0033794989 scopus 로고    scopus 로고
    • Tissue disposition of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in maternal and developing Long-Evans rats following subchronic exposure
    • Hurst C.H., De Vito M.J., and Birnbaum L.S. Tissue disposition of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in maternal and developing Long-Evans rats following subchronic exposure. Toxicol. Sci. 57 (2000) 275-283
    • (2000) Toxicol. Sci. , vol.57 , pp. 275-283
    • Hurst, C.H.1    De Vito, M.J.2    Birnbaum, L.S.3
  • 22
    • 33847691141 scopus 로고    scopus 로고
    • JECFA, 2001. Summary of the fifty-seventh meeting of the Joint FAO/WHO Expert Committee on Food Additives, Rome, 5-14 June 2001, 24-40 http://www.fao.org/es/ESN/Jecfa/57corr.pdf.
  • 23
    • 0018074887 scopus 로고
    • Results of the two year toxicity and ontogenicity study of 2,3,47,8-tetrachlorodibenzo-p-dioxin
    • Kociba R.J., Keyes D.G., Beyer J., et al. Results of the two year toxicity and ontogenicity study of 2,3,47,8-tetrachlorodibenzo-p-dioxin. Toxicol. Appl. Pharmacol. 46 (1978) 279-303
    • (1978) Toxicol. Appl. Pharmacol. , vol.46 , pp. 279-303
    • Kociba, R.J.1    Keyes, D.G.2    Beyer, J.3
  • 24
    • 0027984801 scopus 로고
    • Effects of dioxins and polychlorinated biphenyls on thyroid hormone status of pregnant women and their infants
    • Koopman-Esseboom C., Morse D.C., Weisglas-Kuperus N., et al. Effects of dioxins and polychlorinated biphenyls on thyroid hormone status of pregnant women and their infants. Pediatr. Res. 36 (1994) 468-473
    • (1994) Pediatr. Res. , vol.36 , pp. 468-473
    • Koopman-Esseboom, C.1    Morse, D.C.2    Weisglas-Kuperus, N.3
  • 25
    • 0030977083 scopus 로고    scopus 로고
    • 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and congeners in infants
    • Kreuzer P.E., Csanady G.A., Baur C., et al. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and congeners in infants. Arch. Toxicol 71 (1997) 383-400
    • (1997) Arch. Toxicol , vol.71 , pp. 383-400
    • Kreuzer, P.E.1    Csanady, G.A.2    Baur, C.3
  • 26
    • 19944433564 scopus 로고    scopus 로고
    • Biomonitoring of persistent organochlorine pestizides, PCDD/PCDFs an dioxin-like PCBs in blood of children from South West Germany (Baden-Wuerttemberg) from 1993 to 2003
    • Link B., Gabrio T., Zoellner I., et al. Biomonitoring of persistent organochlorine pestizides, PCDD/PCDFs an dioxin-like PCBs in blood of children from South West Germany (Baden-Wuerttemberg) from 1993 to 2003. Chemosphere 58 (2005) 1185-1201
    • (2005) Chemosphere , vol.58 , pp. 1185-1201
    • Link, B.1    Gabrio, T.2    Zoellner, I.3
  • 27
    • 0026755842 scopus 로고
    • In utero and lactational exposure of male rats to 2,3,7,8-tetrachlorodibenzo-p-dioxin. 3. Effects on spermatogenesis and reproductive capability
    • Mably T.A., Bjerke D.L., Moore R.W., et al. In utero and lactational exposure of male rats to 2,3,7,8-tetrachlorodibenzo-p-dioxin. 3. Effects on spermatogenesis and reproductive capability. Toxicol. Appl. Pharmacol. 114 (1992) 118-126
    • (1992) Toxicol. Appl. Pharmacol. , vol.114 , pp. 118-126
    • Mably, T.A.1    Bjerke, D.L.2    Moore, R.W.3
  • 28
    • 0026591243 scopus 로고
    • Polyhalogenated dibenzo-p-dioxins and dibenzofurans and the immune system. IV. Effects of multiple-dose treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on peripheral lymphocyte subpopulations of a non-human primate (Callithrix jacchus)
    • Neubert R., Golor G., Stahlmann R., et al. Polyhalogenated dibenzo-p-dioxins and dibenzofurans and the immune system. IV. Effects of multiple-dose treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on peripheral lymphocyte subpopulations of a non-human primate (Callithrix jacchus). Arch. Toxicol. 66 (1992) 250-259
    • (1992) Arch. Toxicol. , vol.66 , pp. 250-259
    • Neubert, R.1    Golor, G.2    Stahlmann, R.3
  • 29
    • 17744400089 scopus 로고    scopus 로고
    • Maternal exposure to a low dose of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) suppressed the development of reproductive organs of male rats: dose-dependant increase of mRNA levels of 5 α-reductase type 2 in contrast to decrease of androgen receptor in the pubertal ventral prostate
    • Ohsako S., Miyabara Y., Nishimura N., et al. Maternal exposure to a low dose of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) suppressed the development of reproductive organs of male rats: dose-dependant increase of mRNA levels of 5 α-reductase type 2 in contrast to decrease of androgen receptor in the pubertal ventral prostate. Toxicol. Sci. 60 (2001) 132-143
    • (2001) Toxicol. Sci. , vol.60 , pp. 132-143
    • Ohsako, S.1    Miyabara, Y.2    Nishimura, N.3
  • 30
    • 2042534631 scopus 로고    scopus 로고
    • PCDD/PCDF: Human background data for Germany, a 10-year experience
    • Päpke O. PCDD/PCDF: Human background data for Germany, a 10-year experience. Environ. Health Perspect. 106 Suppl. 2 (1998) 723-731
    • (1998) Environ. Health Perspect. , vol.106 , Issue.SUPPL. 2 , pp. 723-731
    • Päpke, O.1
  • 31
    • 0033043326 scopus 로고    scopus 로고
    • Dietary exposure to polychlorinated biphenyls and dioxins from infancy until adulthood: a comparison between breast-feeding, toddler, and long term exposure
    • Patandin S., Dagnelie P.C., Mulder P.G.H., et al. Dietary exposure to polychlorinated biphenyls and dioxins from infancy until adulthood: a comparison between breast-feeding, toddler, and long term exposure. Environ. Health Perspect. 107 (1999) 45-51
    • (1999) Environ. Health Perspect. , vol.107 , pp. 45-51
    • Patandin, S.1    Dagnelie, P.C.2    Mulder, P.G.H.3
  • 32
    • 0022871514 scopus 로고
    • Pharmacokinetics of 2,3,7,8-TCDD in man
    • Poiger H., and Schlatter C. Pharmacokinetics of 2,3,7,8-TCDD in man. Chemosphere 15 (1986) 1489-1495
    • (1986) Chemosphere , vol.15 , pp. 1489-1495
    • Poiger, H.1    Schlatter, C.2
  • 33
    • 77957184774 scopus 로고
    • Endometriosis in rhesus monkeys (Macaca mulatta) following chronic exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin
    • Rier S.E., Martin D.C., Bowman R.E., et al. Endometriosis in rhesus monkeys (Macaca mulatta) following chronic exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Fundam. Appl. Toxicol. 21 (1993) 433-441
    • (1993) Fundam. Appl. Toxicol. , vol.21 , pp. 433-441
    • Rier, S.E.1    Martin, D.C.2    Bowman, R.E.3
  • 34
    • 33847650505 scopus 로고    scopus 로고
    • SCF, Scientific Committee on Food 2000. Opinion of the SCF on the risk assessment of dioxins and dioxin-like PCBs in food. European Commission, Brussels, Adopted on November 2000 http://europa.eu.int/comm/food/fs/sc/scf/out78_en.pdf.
  • 35
    • 33847654748 scopus 로고    scopus 로고
    • SCF Scientific Committee on Food 2001. Opinion of the SCF on the risk assessment of dioxins and dioxin-like PCBs in food. European Commission, Brussels, Update based on new scientific information available since the adoption of the SCF opinion of 22. November 2000. Adopted on 30 May 2001 http://europa.eu.int/comm/food/fs/sc/scf/out90_en.pdf.
  • 36
    • 0024594287 scopus 로고
    • Learning in monkeys exposed perinatally to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)
    • Schantz S.L., and Bowman R.E. Learning in monkeys exposed perinatally to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Neurotoxicol. Teratol. 11 (1989) 13-19
    • (1989) Neurotoxicol. Teratol. , vol.11 , pp. 13-19
    • Schantz, S.L.1    Bowman, R.E.2
  • 37
    • 0032191508 scopus 로고    scopus 로고
    • Partitioning of dioxins, dibenzofurans, and coplanar PCBs in blood, milk, adipose tissue, placenta and cord blood from five American women
    • Schecter A., Kassis I., and Päpke O. Partitioning of dioxins, dibenzofurans, and coplanar PCBs in blood, milk, adipose tissue, placenta and cord blood from five American women. Chemosphere 37 9-12 (1998) 1817-1823
    • (1998) Chemosphere , vol.37 , Issue.9-12 , pp. 1817-1823
    • Schecter, A.1    Kassis, I.2    Päpke, O.3
  • 38
    • 33847622532 scopus 로고    scopus 로고
    • UBA, 1985. Federal Environmental Agency Sachstand Dioxine, UBA-Bericht 5/85.
  • 39
    • 33847611559 scopus 로고    scopus 로고
    • UBA, 2002. Comments on the "Opinion of the Scientific Committee on Food on the Risk Assessment of Dioxins and Dioxin-like PCB in Food. Update dated 30 May 2001 of the SCF Opinion of 22 November 2000 CS/CNTM/DIOXIN/20 final" by the German Federal Environmental Agency (UBA) from 20 December 2002. http://www.umweltdaten.de/daten/SCF-comment2002-final.pdf.
  • 40
    • 33847626646 scopus 로고    scopus 로고
    • Umweltbundesamt, 1999. Dietary intake of arsen, lead, cadmium, chromium, nickel, mercury, selen and zinc as well as polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/F) and polychlorinated aromatic hydrocarbons via food by children as measured by the duplicate method, FKZ-No. 29765124 (in German).
  • 41
    • 18844403937 scopus 로고    scopus 로고
    • Body burden of polychlorinated dibenzo-p-dioxins, dibenzofurans and biphenyls in pregnant woman and their infants - correlation between prenatal and postnatal exposure to infants
    • Wang S.J., Guo Y.L., Lin C., et al. Body burden of polychlorinated dibenzo-p-dioxins, dibenzofurans and biphenyls in pregnant woman and their infants - correlation between prenatal and postnatal exposure to infants. Organohalogen Comp. 55 (2002) 255-258
    • (2002) Organohalogen Comp. , vol.55 , pp. 255-258
    • Wang, S.J.1    Guo, Y.L.2    Lin, C.3
  • 42
    • 0034521387 scopus 로고    scopus 로고
    • Immunologic effects of background exposure to polychlorinated biphenyls and dioxins in Dutch preschool children
    • Weisglas-Kuperus N., Pantandin S., Berbers G.A.M., et al. Immunologic effects of background exposure to polychlorinated biphenyls and dioxins in Dutch preschool children. Environ. Health Perspect. 108 (2000) 1203-1207
    • (2000) Environ. Health Perspect. , vol.108 , pp. 1203-1207
    • Weisglas-Kuperus, N.1    Pantandin, S.2    Berbers, G.A.M.3
  • 43
    • 0034088182 scopus 로고    scopus 로고
    • Assessment of the health risk of dioxins: re-evaluation of the tolerable daily intake (TDI): executive summary
    • WHO. Assessment of the health risk of dioxins: re-evaluation of the tolerable daily intake (TDI): executive summary. Food Add. Contam. 17 (2000) 223-240
    • (2000) Food Add. Contam. , vol.17 , pp. 223-240
    • WHO1
  • 44
    • 33847625940 scopus 로고    scopus 로고
    • Wicklund Glynn, A., Darnerud, PO., Andersson, Ö., Atuma, S., Johnsson, H., Linder, C-E., Becker, W. 1996. Revised fish consumption advisory regarding PCBs and dioxins. Report 4/96 (p. 47), National Food Administration.
  • 45
    • 0035031033 scopus 로고    scopus 로고
    • Dietary intake of PCDD/F by small children with different food consumption measured by the duplicate method
    • Wittsiepe J., Schrey P., and Wilhelm M. Dietary intake of PCDD/F by small children with different food consumption measured by the duplicate method. Chemosphere 43 2001 (2001) 881-887
    • (2001) Chemosphere , vol.43 , Issue.2001 , pp. 881-887
    • Wittsiepe, J.1    Schrey, P.2    Wilhelm, M.3


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