메뉴 건너뛰기




Volumn 42, Issue 6, 2012, Pages 1488-1499

Epitope specificity of memory CD8 + T cells dictates vaccination-induced mortality in LCMV-infected perforin-deficient mice

Author keywords

Animal models; CD8 + T cells; Cytotoxicity; Vaccination

Indexed keywords

EPITOPE; GAMMA INTERFERON; GRANZYME B;

EID: 84862118587     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201142263     Document Type: Article
Times cited : (6)

References (59)
  • 1
    • 33745073790 scopus 로고    scopus 로고
    • Programming, demarcating, and manipulating CD8+ T-cell memory
    • Badovinac, V. P.andHarty, J. T., Programming, demarcating, and manipulating CD8+ T-cell memory. Immunol. Rev. 2006. 211: 67-80.
    • (2006) Immunol. Rev. , vol.211 , pp. 67-80
    • Badovinac, V.P.1    Harty, J.T.2
  • 2
    • 38549096234 scopus 로고    scopus 로고
    • Shaping and reshaping CD8+ T-cell memory
    • Harty, J. T.andBadovinac, V. P., Shaping and reshaping CD8+ T-cell memory. Nat. Rev. Immunol. 2008. 8: 107-119.
    • (2008) Nat. Rev. Immunol. , vol.8 , pp. 107-119
    • Harty, J.T.1    Badovinac, V.P.2
  • 3
    • 0036550559 scopus 로고    scopus 로고
    • Effector and memory T-cell differentiation: implications for vaccine development
    • Kaech, S. M., Wherry, E. J.andAhmed, R., Effector and memory T-cell differentiation: implications for vaccine development. Nat. Rev. Immunol. 2002. 2: 251-262.
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 251-262
    • Kaech, S.M.1    Wherry, E.J.2    Ahmed, R.3
  • 5
    • 2442684151 scopus 로고    scopus 로고
    • Memory CD8 T-cell differentiation during viral infection
    • Wherry, E. J.andAhmed, R., Memory CD8 T-cell differentiation during viral infection. J. Virol. 2004. 78: 5535-5545.
    • (2004) J. Virol. , vol.78 , pp. 5535-5545
    • Wherry, E.J.1    Ahmed, R.2
  • 6
    • 34247849183 scopus 로고    scopus 로고
    • Effector and memory CTL differentiation
    • Williams, M. A.andBevan, M. J., Effector and memory CTL differentiation. Annu. Rev. Immunol. 2007. 25: 171-192.
    • (2007) Annu. Rev. Immunol. , vol.25 , pp. 171-192
    • Williams, M.A.1    Bevan, M.J.2
  • 7
    • 0036604931 scopus 로고    scopus 로고
    • Influence of effector molecules on the CD8(+) T-cell response to infection
    • Harty, J. T.andBadovinac, V. P., Influence of effector molecules on the CD8(+) T-cell response to infection. Curr. Opin. Immunol. 2002. 14: 360-365.
    • (2002) Curr. Opin. Immunol. , vol.14 , pp. 360-365
    • Harty, J.T.1    Badovinac, V.P.2
  • 8
    • 0033678990 scopus 로고    scopus 로고
    • Antigen-specific regulation of T cell-mediated cytokine production
    • Slifka, M. K.andWhitton, J. L., Antigen-specific regulation of T cell-mediated cytokine production. Immunity 2000. 12: 451-457.
    • (2000) Immunity , vol.12 , pp. 451-457
    • Slifka, M.K.1    Whitton, J.L.2
  • 9
    • 0028219791 scopus 로고
    • Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice
    • Kagi, D., Ledermann, B., Burki, K., Seiler, P., Odermatt, B., Olsen, K. J., Podack, E. R.et al., Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice. Nature 1994. 369: 31-37.
    • (1994) Nature , vol.369 , pp. 31-37
    • Kagi, D.1    Ledermann, B.2    Burki, K.3    Seiler, P.4    Odermatt, B.5    Olsen, K.J.6    Podack, E.R.7
  • 12
    • 0034680811 scopus 로고    scopus 로고
    • Regulation of antigen-specific CD8+ T-cell homeostasis by perforin and interferon-gamma
    • Badovinac, V. P., Tvinnereim, A. R.andHarty, J. T., Regulation of antigen-specific CD8+ T-cell homeostasis by perforin and interferon-gamma. Science 2000. 290: 1354-1358.
    • (2000) Science , vol.290 , pp. 1354-1358
    • Badovinac, V.P.1    Tvinnereim, A.R.2    Harty, J.T.3
  • 13
    • 0032482176 scopus 로고    scopus 로고
    • Induction and exhaustion of lymphocytic choriomeningitis virus-specific cytotoxic T lymphocytes visualized using soluble tetrameric major histocompatibility complex class I-peptide complexes
    • Gallimore, A., Glithero, A., Godkin, A., Tissot, A. C., Pluckthun, A., Elliott, T., Hengartner, H.andZinkernagel, R., Induction and exhaustion of lymphocytic choriomeningitis virus-specific cytotoxic T lymphocytes visualized using soluble tetrameric major histocompatibility complex class I-peptide complexes. J. Exp. Med. 1998. 187: 1383-1393.
    • (1998) J. Exp. Med. , vol.187 , pp. 1383-1393
    • Gallimore, A.1    Glithero, A.2    Godkin, A.3    Tissot, A.C.4    Pluckthun, A.5    Elliott, T.6    Hengartner, H.7    Zinkernagel, R.8
  • 14
    • 0032980707 scopus 로고    scopus 로고
    • A role for perforin in downregulating T-cell responses during chronic viral infection
    • Matloubian, M., Suresh, M., Glass, A., Galvan, M., Chow, K., Whitmire, J. K., Walsh, C. M.et al., A role for perforin in downregulating T-cell responses during chronic viral infection. J. Virol. 1999. 73: 2527-2536.
    • (1999) J. Virol. , vol.73 , pp. 2527-2536
    • Matloubian, M.1    Suresh, M.2    Glass, A.3    Galvan, M.4    Chow, K.5    Whitmire, J.K.6    Walsh, C.M.7
  • 15
    • 0033555391 scopus 로고    scopus 로고
    • A role for perforin in activation-induced T-cell death in vivo: increased expansion of allogeneic perforin-deficient T cells in SCID mice
    • Spaner, D., Raju, K., Rabinovich, B.andMiller, R. G., A role for perforin in activation-induced T-cell death in vivo: increased expansion of allogeneic perforin-deficient T cells in SCID mice. J. Immunol. 1999. 162: 1192-1199.
    • (1999) J. Immunol. , vol.162 , pp. 1192-1199
    • Spaner, D.1    Raju, K.2    Rabinovich, B.3    Miller, R.G.4
  • 16
    • 0242417491 scopus 로고    scopus 로고
    • Viral infection results in massive CD8+ T-cell expansion and mortality in vaccinated perforin-deficient mice
    • Badovinac, V. P., Hamilton, S. E.andHarty, J. T., Viral infection results in massive CD8+ T-cell expansion and mortality in vaccinated perforin-deficient mice. Immunity 2003. 18: 463-474.
    • (2003) Immunity , vol.18 , pp. 463-474
    • Badovinac, V.P.1    Hamilton, S.E.2    Harty, J.T.3
  • 18
    • 3242752040 scopus 로고    scopus 로고
    • An animal model of hemophagocytic lymphohistiocytosis (HLH): CD8+ T cells and interferon gamma are essential for the disorder
    • Jordan, M. B., Hildeman, D., Kappler, J.andMarrack, P., An animal model of hemophagocytic lymphohistiocytosis (HLH): CD8+ T cells and interferon gamma are essential for the disorder. Blood 2004. 104: 735-743.
    • (2004) Blood , vol.104 , pp. 735-743
    • Jordan, M.B.1    Hildeman, D.2    Kappler, J.3    Marrack, P.4
  • 19
    • 13144259647 scopus 로고    scopus 로고
    • Primary hemophagocytic syndromes point to a direct link between lymphocyte cytotoxicity and homeostasis
    • Menasche, G., Feldmann, J., Fischer, A.andde Saint Basile, G., Primary hemophagocytic syndromes point to a direct link between lymphocyte cytotoxicity and homeostasis. Immunol. Rev. 2005. 203: 165-179.
    • (2005) Immunol. Rev. , vol.203 , pp. 165-179
    • Menasche, G.1    Feldmann, J.2    Fischer, A.3    de Saint Basile, G.4
  • 20
    • 79551703613 scopus 로고    scopus 로고
    • Familial haemophagocytic lymphohistiocytosis: advances in the genetic basis, diagnosis and management
    • Gholam, C., Grigoriadou, S., Gilmour, K. C.andGaspar, H. B., Familial haemophagocytic lymphohistiocytosis: advances in the genetic basis, diagnosis and management. Clin. Exp. Immunol. 2011. 163: 271-283.
    • (2011) Clin. Exp. Immunol. , vol.163 , pp. 271-283
    • Gholam, C.1    Grigoriadou, S.2    Gilmour, K.C.3    Gaspar, H.B.4
  • 21
    • 0027178380 scopus 로고
    • Familial hemophagocytic lymphohistiocytosis and viral infections
    • Henter, J. I., Ehrnst, A., Andersson, J.andElinder, G., Familial hemophagocytic lymphohistiocytosis and viral infections. Acta. Paediatr. 1993. 82: 369-372.
    • (1993) Acta. Paediatr. , vol.82 , pp. 369-372
    • Henter, J.I.1    Ehrnst, A.2    Andersson, J.3    Elinder, G.4
  • 22
    • 15944399347 scopus 로고    scopus 로고
    • Perforin and lymphohistiocytic proliferative disorders
    • Katano, H.andCohen, J. I., Perforin and lymphohistiocytic proliferative disorders. Br. J. Haematol. 2005. 128: 739-750.
    • (2005) Br. J. Haematol. , vol.128 , pp. 739-750
    • Katano, H.1    Cohen, J.I.2
  • 23
    • 0037105371 scopus 로고    scopus 로고
    • Adult onset and atypical presentation of hemophagocytic lymphohistiocytosis in siblings carrying PRF1 mutations
    • Clementi, R., Emmi, L., Maccario, R., Liotta, F., Moretta, L., Danesino, C.andArico, M., Adult onset and atypical presentation of hemophagocytic lymphohistiocytosis in siblings carrying PRF1 mutations. Blood 2002. 100: 2266-2267.
    • (2002) Blood , vol.100 , pp. 2266-2267
    • Clementi, R.1    Emmi, L.2    Maccario, R.3    Liotta, F.4    Moretta, L.5    Danesino, C.6    Arico, M.7
  • 24
    • 1242292327 scopus 로고    scopus 로고
    • Characterisation of diverse PRF1 mutations leading to decreased natural killer cell activity in North American families with haemophagocytic lymphohistiocytosis
    • Molleran Lee, S., Villanueva, J., Sumegi, J., Zhang, K., Kogawa, K., Davis, J.andFilipovich, A. H., Characterisation of diverse PRF1 mutations leading to decreased natural killer cell activity in North American families with haemophagocytic lymphohistiocytosis. J. Med. Genet. 2004. 41: 137-144.
    • (2004) J. Med. Genet. , vol.41 , pp. 137-144
    • Molleran Lee, S.1    Villanueva, J.2    Sumegi, J.3    Zhang, K.4    Kogawa, K.5    Davis, J.6    Filipovich, A.H.7
  • 25
    • 34249812697 scopus 로고    scopus 로고
    • Late-onset cases of familial hemophagocytic lymphohistiocytosis with missense perforin gene mutations
    • Ueda, I., Kurokawa, Y., Koike, K., Ito, S., Sakata, A., Matsumora, T., Fukushima, T.et al., Late-onset cases of familial hemophagocytic lymphohistiocytosis with missense perforin gene mutations. Am. J. Hematol. 2007. 82: 427-432.
    • (2007) Am. J. Hematol. , vol.82 , pp. 427-432
    • Ueda, I.1    Kurokawa, Y.2    Koike, K.3    Ito, S.4    Sakata, A.5    Matsumora, T.6    Fukushima, T.7
  • 26
    • 0141958141 scopus 로고    scopus 로고
    • Deficient anti-listerial immunity in the absence of perforin can be restored by increasing memory CD8+ T-cell numbers
    • Messingham, K. A., Badovinac, V. P.andHarty, J. T., Deficient anti-listerial immunity in the absence of perforin can be restored by increasing memory CD8+ T-cell numbers. J. Immunol. 2003. 171: 4254-4262.
    • (2003) J. Immunol. , vol.171 , pp. 4254-4262
    • Messingham, K.A.1    Badovinac, V.P.2    Harty, J.T.3
  • 27
    • 0033555893 scopus 로고    scopus 로고
    • Perforin-deficient CD8+ T cells: in vivo priming and antigen-specific immunity against Listeria monocytogenes
    • White, D. W., MacNeil, A., Busch, D. H., Pilip, I. M., Pamer, E. G.andHarty, J. T., Perforin-deficient CD8+ T cells: in vivo priming and antigen-specific immunity against Listeria monocytogenes. J. Immunol. 1999. 162: 980-988.
    • (1999) J. Immunol. , vol.162 , pp. 980-988
    • White, D.W.1    MacNeil, A.2    Busch, D.H.3    Pilip, I.M.4    Pamer, E.G.5    Harty, J.T.6
  • 28
    • 0029133459 scopus 로고
    • Specific immunity to Listeria monocytogenes in the absence of IFN gamma
    • Harty, J. T.andBevan, M. J., Specific immunity to Listeria monocytogenes in the absence of IFN gamma. Immunity 1995. 3: 109-117.
    • (1995) Immunity , vol.3 , pp. 109-117
    • Harty, J.T.1    Bevan, M.J.2
  • 29
    • 0033943625 scopus 로고    scopus 로고
    • Adaptive immunity against Listeria monocytogenes in the absence of type I tumor necrosis factor receptor p55
    • White, D. W., Badovinac, V. P., Fan, X.andHarty, J. T., Adaptive immunity against Listeria monocytogenes in the absence of type I tumor necrosis factor receptor p55. Infect Immun. 2000. 68: 4470-4476.
    • (2000) Infect Immun. , vol.68 , pp. 4470-4476
    • White, D.W.1    Badovinac, V.P.2    Fan, X.3    Harty, J.T.4
  • 30
    • 0031985628 scopus 로고    scopus 로고
    • Perforin-deficient CD8+ T cells provide immunity to Listeria monocytogenes by a mechanism that is independent of CD95 and IFN-gamma but requires TNF-alpha
    • White, D. W.andHarty, J. T., Perforin-deficient CD8+ T cells provide immunity to Listeria monocytogenes by a mechanism that is independent of CD95 and IFN-gamma but requires TNF-alpha. J. Immunol. 1998. 160: 898-905.
    • (1998) J. Immunol. , vol.160 , pp. 898-905
    • White, D.W.1    Harty, J.T.2
  • 32
    • 34250175093 scopus 로고    scopus 로고
    • Initial T-cell receptor transgenic cell precursor frequency dictates critical aspects of the CD8(+) T-cell response to infection
    • Badovinac, V. P., Haring, J. S.andHarty, J. T., Initial T-cell receptor transgenic cell precursor frequency dictates critical aspects of the CD8(+) T-cell response to infection. Immunity 2007. 26: 827-841.
    • (2007) Immunity , vol.26 , pp. 827-841
    • Badovinac, V.P.1    Haring, J.S.2    Harty, J.T.3
  • 33
    • 0035348175 scopus 로고    scopus 로고
    • Memory CD8+ T-cell differentiation: initial antigen encounter triggers a developmental program in naive cells
    • Kaech, S. M.andAhmed, R., Memory CD8+ T-cell differentiation: initial antigen encounter triggers a developmental program in naive cells. Nat. Immunol. 2001. 2: 415-422.
    • (2001) Nat. Immunol. , vol.2 , pp. 415-422
    • Kaech, S.M.1    Ahmed, R.2
  • 34
    • 0030921459 scopus 로고    scopus 로고
    • Uncovering subdominant cytotoxic T-lymphocyte responses in lymphocytic choriomeningitis virus-infected BALB/c mice
    • van der
    • van der Most, R. G., Concepcion, R. J., Oseroff, C., Alexander, J., Southwood, S., Sidney, J., Chesnut, R. W.et al., Uncovering subdominant cytotoxic T-lymphocyte responses in lymphocytic choriomeningitis virus-infected BALB/c mice. J. Virol. 1997. 71: 5110-5114.
    • (1997) J. Virol. , vol.71 , pp. 5110-5114
    • Most, R.G.1    Concepcion, R.J.2    Oseroff, C.3    Alexander, J.4    Southwood, S.5    Sidney, J.6    Chesnut, R.W.7
  • 35
    • 2642704191 scopus 로고    scopus 로고
    • Relationship among immunodominance of single CD8+ T-cell epitopes, virus load, and kinetics of primary antiviral CTL response
    • Weidt, G., Utermohlen, O., Heukeshoven, J., Lehmann-Grube, F.andDeppert, W., Relationship among immunodominance of single CD8+ T-cell epitopes, virus load, and kinetics of primary antiviral CTL response. J. Immunol. 1998. 160: 2923-2931.
    • (1998) J. Immunol. , vol.160 , pp. 2923-2931
    • Weidt, G.1    Utermohlen, O.2    Heukeshoven, J.3    Lehmann-Grube, F.4    Deppert, W.5
  • 36
    • 0032543212 scopus 로고    scopus 로고
    • Protective immunity does not correlate with the hierarchy of virus-specific cytotoxic T-cell responses to naturally processed peptides
    • Gallimore, A., Dumrese, T., Hengartner, H., Zinkernagel, R. M.andRammensee, H. G., Protective immunity does not correlate with the hierarchy of virus-specific cytotoxic T-cell responses to naturally processed peptides. J. Exp. Med. 1998. 187: 1647-1657.
    • (1998) J. Exp. Med. , vol.187 , pp. 1647-1657
    • Gallimore, A.1    Dumrese, T.2    Hengartner, H.3    Zinkernagel, R.M.4    Rammensee, H.G.5
  • 37
    • 0035881946 scopus 로고    scopus 로고
    • Dynamic antigen presentation patterns of Listeria monocytogenes-derived CD8 T-cell epitopes in vivo
    • Skoberne, M., Holtappels, R., Hof, H.andGeginat, G., Dynamic antigen presentation patterns of Listeria monocytogenes-derived CD8 T-cell epitopes in vivo. J. Immunol. 2001. 167: 2209-2218.
    • (2001) J. Immunol. , vol.167 , pp. 2209-2218
    • Skoberne, M.1    Holtappels, R.2    Hof, H.3    Geginat, G.4
  • 39
    • 57849168934 scopus 로고    scopus 로고
    • Coregulation of CD8+ T-cell exhaustion by multiple inhibitory receptors during chronic viral infection
    • Blackburn, S. D., Shin, H., Haining, W. N., Zou, T., Workman, C. J., Polley, A., Betts, M. R.et al., Coregulation of CD8+ T-cell exhaustion by multiple inhibitory receptors during chronic viral infection. Nat. Immunol. 2009. 10: 29-37.
    • (2009) Nat. Immunol. , vol.10 , pp. 29-37
    • Blackburn, S.D.1    Shin, H.2    Haining, W.N.3    Zou, T.4    Workman, C.J.5    Polley, A.6    Betts, M.R.7
  • 40
    • 0032005477 scopus 로고    scopus 로고
    • Counting antigen-specific CD8 T cells: a reevaluation of bystander activation during viral infection
    • Murali-Krishna, K., Altman, J. D., Suresh, M., Sourdive, D. J., Zajac, A. J., Miller, J. D., Slansky, J.et al., Counting antigen-specific CD8 T cells: a reevaluation of bystander activation during viral infection. Immunity 1998. 8: 177-187.
    • (1998) Immunity , vol.8 , pp. 177-187
    • Murali-Krishna, K.1    Altman, J.D.2    Suresh, M.3    Sourdive, D.J.4    Zajac, A.J.5    Miller, J.D.6    Slansky, J.7
  • 41
    • 0029914331 scopus 로고    scopus 로고
    • Molecular mechanisms of lymphocyte-mediated cytotoxicity and their role in immunological protection and pathogenesis in vivo
    • Kagi, D., Ledermann, B., Burki, K., Zinkernagel, R. M.andHengartner, H., Molecular mechanisms of lymphocyte-mediated cytotoxicity and their role in immunological protection and pathogenesis in vivo. Annu. Rev. Immunol. 1996. 14: 207-232.
    • (1996) Annu. Rev. Immunol. , vol.14 , pp. 207-232
    • Kagi, D.1    Ledermann, B.2    Burki, K.3    Zinkernagel, R.M.4    Hengartner, H.5
  • 43
    • 0036302172 scopus 로고    scopus 로고
    • Programmed contraction of CD8(+) T cells after infection
    • Badovinac, V. P., Porter, B. B.andHarty, J. T., Programmed contraction of CD8(+) T cells after infection. Nat. Immunol. 2002. 3: 619-626.
    • (2002) Nat. Immunol. , vol.3 , pp. 619-626
    • Badovinac, V.P.1    Porter, B.B.2    Harty, J.T.3
  • 45
    • 0034115161 scopus 로고    scopus 로고
    • Clinical implications of dysregulated cytokine production
    • Slifka, M. K.andWhitton, J. L., Clinical implications of dysregulated cytokine production. J. Mol. Med. (Berl) 2000. 78: 74-80.
    • (2000) J. Mol. Med. (Berl) , vol.78 , pp. 74-80
    • Slifka, M.K.1    Whitton, J.L.2
  • 46
    • 0034669954 scopus 로고    scopus 로고
    • Cutting edge: off cycling of TNF production by antigen-specific CD8+ T cells is antigen independent
    • Badovinac, V. P., Corbin, G. A.andHarty, J. T., Cutting edge: off cycling of TNF production by antigen-specific CD8+ T cells is antigen independent. J. Immunol. 2000. 165: 5387-5391.
    • (2000) J. Immunol. , vol.165 , pp. 5387-5391
    • Badovinac, V.P.1    Corbin, G.A.2    Harty, J.T.3
  • 47
    • 0033517288 scopus 로고    scopus 로고
    • Rapid on/off cycling of cytokine production by virus-specific CD8+T cells
    • Slifka, M. K., Rodriguez, F.andWhitton, J. L., Rapid on/off cycling of cytokine production by virus-specific CD8+T cells. Nature 1999. 401: 76-79.
    • (1999) Nature , vol.401 , pp. 76-79
    • Slifka, M.K.1    Rodriguez, F.2    Whitton, J.L.3
  • 48
    • 0029956511 scopus 로고    scopus 로고
    • Perforin and Fas killing by CD8+ T cells limits their cytokine synthesis and proliferation
    • Sad, S., Kagi, D.andMosmann, T. R., Perforin and Fas killing by CD8+ T cells limits their cytokine synthesis and proliferation. J. Exp. Med. 1996. 184: 1543-1547.
    • (1996) J. Exp. Med. , vol.184 , pp. 1543-1547
    • Sad, S.1    Kagi, D.2    Mosmann, T.R.3
  • 49
    • 79960714121 scopus 로고    scopus 로고
    • Perforin is a critical physiologic regulator of T-cell activation
    • Lykens, J. E., Terrell, C. E., Zoller, E. E., Risma, K.andJordan, M. B., Perforin is a critical physiologic regulator of T-cell activation. Blood 2011. 118: 618-626.
    • (2011) Blood , vol.118 , pp. 618-626
    • Lykens, J.E.1    Terrell, C.E.2    Zoller, E.E.3    Risma, K.4    Jordan, M.B.5
  • 50
    • 80052279263 scopus 로고    scopus 로고
    • The herpes simplex virus 1 latency-associated transcript promotes functional exhaustion of virus-specific CD8+ T cells in latently infected trigeminal ganglia: a novel immune evasion mechanism
    • Chentoufi, A. A., Kritzer, E., Tran, M. V., Dasgupta, G., Lim, C. H., Yu, D. C., Afifi, R. E.et al., The herpes simplex virus 1 latency-associated transcript promotes functional exhaustion of virus-specific CD8+ T cells in latently infected trigeminal ganglia: a novel immune evasion mechanism. J. Virol. 2011. 85: 9127-9138.
    • (2011) J. Virol. , vol.85 , pp. 9127-9138
    • Chentoufi, A.A.1    Kritzer, E.2    Tran, M.V.3    Dasgupta, G.4    Lim, C.H.5    Yu, D.C.6    Afifi, R.E.7
  • 51
    • 80053466563 scopus 로고    scopus 로고
    • Virus-specific CD8+ T cells upregulate programmed death-1 expression during acute friend retrovirus infection but are highly cytotoxic and control virus replication
    • Zelinskyy, G., Myers, L., Dietze, K. K., Gibbert, K., Roggendorf, M., Liu, J., Lu, M.et al., Virus-specific CD8+ T cells upregulate programmed death-1 expression during acute friend retrovirus infection but are highly cytotoxic and control virus replication. J. Immunol. 2011. 187: 3730-3737.
    • (2011) J. Immunol. , vol.187 , pp. 3730-3737
    • Zelinskyy, G.1    Myers, L.2    Dietze, K.K.3    Gibbert, K.4    Roggendorf, M.5    Liu, J.6    Lu, M.7
  • 52
    • 70149106207 scopus 로고    scopus 로고
    • A default pathway of memory CD8 T-cell differentiation after dendritic cell immunization is deflected by encounter with inflammatory cytokines during antigen-driven proliferation
    • Pham, N. L., Badovinac, V. P.andHarty, J. T., A default pathway of memory CD8 T-cell differentiation after dendritic cell immunization is deflected by encounter with inflammatory cytokines during antigen-driven proliferation. J. Immunol. 2009. 183: 2337-2348.
    • (2009) J. Immunol. , vol.183 , pp. 2337-2348
    • Pham, N.L.1    Badovinac, V.P.2    Harty, J.T.3
  • 53
    • 0027141518 scopus 로고
    • Expression and phosphorylation of the Listeria monocytogenes ActA protein in mammalian cells
    • Brundage, R. A., Smith, G. A., Camilli, A., Theriot, J. A.andPortnoy, D. A., Expression and phosphorylation of the Listeria monocytogenes ActA protein in mammalian cells. Proc. Natl. Acad. Sci. USA 1993. 90: 11890-11894.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 11890-11894
    • Brundage, R.A.1    Smith, G.A.2    Camilli, A.3    Theriot, J.A.4    Portnoy, D.A.5
  • 54
    • 0036137156 scopus 로고    scopus 로고
    • CD8(+)-T-cell response to secreted and nonsecreted antigens delivered by recombinant Listeria monocytogenes during secondary infection
    • Tvinnereim, A. R., Hamilton, S. E.andHarty, J. T., CD8(+)-T-cell response to secreted and nonsecreted antigens delivered by recombinant Listeria monocytogenes during secondary infection. Infect. Immun. 2002. 70: 153-162.
    • (2002) Infect. Immun. , vol.70 , pp. 153-162
    • Tvinnereim, A.R.1    Hamilton, S.E.2    Harty, J.T.3
  • 56
    • 18744430914 scopus 로고    scopus 로고
    • Compartmentalization of bacterial antigens: differential effects on priming of CD8 T cells and protective immunity
    • Shen, H., Miller, J. F., Fan, X., Kolwyck, D., Ahmed, R.andHarty, J. T., Compartmentalization of bacterial antigens: differential effects on priming of CD8 T cells and protective immunity. Cell 1998. 92: 535-545.
    • (1998) Cell , vol.92 , pp. 535-545
    • Shen, H.1    Miller, J.F.2    Fan, X.3    Kolwyck, D.4    Ahmed, R.5    Harty, J.T.6
  • 57
    • 0034697048 scopus 로고    scopus 로고
    • Intracellular staining for TNF and IFN-gamma detects different frequencies of antigen-specific CD8(+) T cells
    • Badovinac, V. P.andHarty, J. T., Intracellular staining for TNF and IFN-gamma detects different frequencies of antigen-specific CD8(+) T cells. J. Immunol. Methods 2000. 238: 107-117.
    • (2000) J. Immunol. Methods , vol.238 , pp. 107-117
    • Badovinac, V.P.1    Harty, J.T.2
  • 59
    • 0032033695 scopus 로고    scopus 로고
    • Coordinate regulation of complex T-cell populations responding to bacterial infection
    • Busch, D. H., Pilip, I. M., Vijh, S.andPamer, E. G., Coordinate regulation of complex T-cell populations responding to bacterial infection. Immunity 1998. 8: 353-362.
    • (1998) Immunity , vol.8 , pp. 353-362
    • Busch, D.H.1    Pilip, I.M.2    Vijh, S.3    Pamer, E.G.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.