Deficient anti-listerial immunity in the absence of perforin can be restored by increasing memory CD8+ T cell numbers

Journal of Immunology

Volumn 171, Issue 8, 2003, Pages 4254-4262

  Nordyke Messingham, Kelly A ^a   Badovinac, Vladimir P ^a   Harty, John T ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD27 ANTIGEN; PADGEM PROTEIN; PERFORIN; T LYMPHOCYTE RECEPTOR;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN SPECIFICITY; ARTICLE; CONTROLLED STUDY; CYTOLYSIS; CYTOTOXICITY; EFFECTOR CELL; FEMALE; FLOW CYTOMETRY; IMMUNITY; LISTERIA MONOCYTOGENES; MEMORY CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPLEEN CELL; T LYMPHOCYTE; VACCINATION;

EID: 0141958141     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.171.8.4254     Document Type: Article

References (43)

1. Kaufmann, S: H., and C. H. Ladel. 1994. Role of T cell subsets in immunity against intracellular bacteria: experimental infections of knock-out mice with Listeria monocytogenes and Mycobacterium bovis BCG. Immunobiology 191:509.
2. 2 microglobulin-deficient mice. Infect. Immun. 61:1113.
3. Ladel, C. H., I. E. Flesch, J. Arnoldi, and S. H. Kaufmann. 1994. Studies with MHC-deficient knock-out mice reveal impact of both MHC I- and MHC II-dependent T cell responses on Listeria monocytogenes infection. J. Immunol. 153:3116.
4. + T cell effector mechanisms in resistance to infection. Annu. Rev. Immunol. 18:275.
5. + T cell-mediated protection against an intracellular bacterium by perforin-dependent cytotoxicity. Eur. J. Immunol. 24:3068.
6. Jensen, E. R., A. A. Glass, W. R. Clark, E. J. Wing, J. F. Miller. and S. H. Gregory. 1998. Fas (CD95)-dependent cell-mediated immunity to Listeria monocytogenes. Infect. Immun. 66:4143.
7. San Mateo, L. R., M. M. Chua, S. R. Weiss, and H. Shen. 2002. Perforin-mediated CTL cytolysis counteracts direct cell-cell spread of Listeria monocytogenes. J. Immunol. 169:5202.
8. + T cells: in vivo priming and antigen-specific immunity against Listeria monocytogenes. J. Immunol. 162:980.
9. + T cells provide immunity to Listeria monocytogenes by a mechanism that is independent of CD95 and IFN-γ but requires TNF-α. J. Immunol. 160:898.
10. + T cell homeostasis by perforin and interferon-γ. Science 290:1354.
11. Shen, H., C. M. Tato, and X. Fan. 1998. Listeria monocytogenes as a probe to study cell-mediated immunity. Curr. Opin. Immunol. 10:450.
12. Shen, H., J. F. Miller, X. Fan, D. Kolwyck, R. Ahmed. and J. T. Harty. 1998. Compartmentalization of bacterial antigens: differential effects on priming of CD8 T cells and protective immunity. Cell 92:535.
13. + T-cell priming against a non-secreted Listeria monocytogenes antigen is independent of the antimicrobial activities of γ interferon. Infect. Immun. 68:2196.
14. Harty, J. T., and M. J. Bevan. 1995. Specific immunity to Listeria monocytogenes in the absence of IFN γ. Immunity 3:109.
15. Harty, J. T., and E. G. Pamer. 1995. CD8 T lymphocytes specific for the secreted p60 antigen protect against Listeria monocytogenes infection. J. Immunol. 154:4642.
16. Pamer, E. G., J. T. Harty, and M. J. Bevan. 1991. Precise prediction of a dominant class I MHC-restricted epitope of Listeria monocytogenes. Nature 353:852.
17. Busch, D. H., H. G. Bouwer, D. Hinrichs, and E. G. Pamer. 1997. A nonamer peptide derived from Listeria monocytogenes metalloprotease is presented to cytolytic T lymphocytes. Infect. Immun. 65:5326.
18. Vijh, S., and E. G. Pamer. 1997. Immunodominant and subdominant CTL responses to Listeria monocytogenes infection. J. Immunol. 158:3366.
19. Lenz, L. L., B. Dere, and M. J. Bevan. 1996. Identification of an H2-M3-restricted Listeria epitope: implications for antigen presentation by M3. Immunity 5:63.
20. + T cells. J. Immunol. Methods 238:107.
21. + T cell expansion, memory, and protective immunity after immunization with peptide-coated dendritic cells. J. Immunol. 169:4936.
22. Coles, R. M., S. N. Mueller, W. R. Heath, F. R. Carbone, and A. G. Brooks. 2002. Progression of armed CTL from draining lymph node to spleen shortly after localized infection with herpes simplex virus 1. J. Immunol. 168:834.
23. Busch, D. H., I. M. Pilip, S. Vijh, and E. G. Pamer. 1998. Coordinate regulation of complex T cell populations responding to bacterial infection. Immunity 8:353.
24. Sallusto, F., D. Lenig, R. Forster, M. Lipp, and A. Lanzavecchia. 1999. Two subsets of memory T lymphocytes with distinct homing potentials and effector functions. Nature 401:708.
25. Masopust, D., V. Vezys, A. Marzo, and L. Lefrancois. 2001. Preferential localization of effector memory cells in nonlymphoid tissue. Science 291:2413.
26. Wherry, E. J., V. Teichgraber, T. C. Becker, D. Masopust, S. M. Kaech, R. Antia, U. H. von Andrian, and R. Ahmed, 2003. Lineage relationship and protective immunity of memory CD8 T cell subsets. Nat. Immunol. 4:225.
27. Blattman, J. N., D. J. Sourdive, K. Murali-Krishna, R. Ahmed. and J. D. Altman. 2000. Evolution of the T cell repertoire during primary, memory, and recall responses to viral infection. J. Immunol. 165:6081.
28. Huleatt, J. W., I. Pilip, K. Kerksiek, and E. G. Pamer. 2001. Intestinal and splenic T cell responses to enteric Listeria monocytogenes infection: distinct repertoires of responding CD8 T lymphocytes. J. Immunol. 166:4065.
29. + T cells without selection of higher affinity TCR. Nat. Immunol. 2:711.
30. Walsh, C. M., M. Matloubian, C. C. Liu, R. Ueda, C. G. Kurahara, J. L. Christensen, M. T. Huang, J. D. Young, R. Ahmed, and W. R. Clark. 1994. Immune function in mice lacking the perforin gene. Proc. Natl. Acad. Sci. USA 91:10854.
31. Kojima, H., N. Shinohara, S. Hanaoka, Y. Someya-Shirota, Y. Takagaki, H. Ohno, T. Saito, T. Katayama, H. Yagita, K. Okumura, et al. 1994. Two distinct pathways of specific killing revealed by perforin mutant cytotoxic T lymphocytes. Immunity 1:357.
32. Lowin, B., M. Hahne, C. Mattmann, and J. Tschopp. 1994. Cytolytic T-cell cytotoxicity is mediated through perforin and Fas lytic pathways. Nature 370:650.
33. + T cells derived from TNF-deficient and TNF/perforin double-deficient mice. J. Immunol. 165:5.
34. + cell effector mechanisms in adaptive immunity to Listeria monocytogenes. Immunobiology 201:196.
35. -/- mice: protection despite absence of ROI and susceptibility despite presence of RNI. Immunity 7:419.
36. Glaser, P., L. Frangeul, C. Buchrieser, C. Rusniok, A. Amend, F. Baquero, P. Berche, H. Bloecker, P. Brandt, T. Chakraborty, et al. 2001. Comparative genomics of Listeria species. Science 294:849.
37. Knabel, M., T. J. Franz, M. Schiemann, A. Wulf, B. Villmow, B. Schmidt, H. Bernhard, H. Wagner, and D. H. Busch. 2002. Reversible MHC multimer staining for functional isolation of T-cell populations and effective adoptive transfer. Nat. Med. 8:631.
38. + T cells by a killed bacterial vaccine. Science 294:1735.
39. Busch, D. H., and E. G. Pamer. 1999. T cell affinity maturation by selective expansion during infection. J. Exp. Med. 189:701.
40. + T-cell responses to influenza virus. J. Virol. 76:10332.
41. + T cells undergoing primary and secondary responses to infection in the same host. J. Immunol. 170:4933.
42. + T cells after infection. Nat. Immunol. 3:619.
43. + T cell expansion and mortality in vaccinated perforin-deficient mice. Immunity 18:463.