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Volumn 78, Issue 2, 2000, Pages 74-80

Clinical implications of dysregulated cytokine production

Author keywords

CD8+ T lymphocyte; Cytokine binding protein; Cytokine regulation; Immunopathology; Septic shock

Indexed keywords

CD8 ANTIGEN; CYTOKINE RECEPTOR; INTERLEUKIN 12; INTERLEUKIN 2; TUMOR NECROSIS FACTOR ALPHA;

EID: 0034115161     PISSN: 09462716     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001090000086     Document Type: Review
Times cited : (115)

References (83)
  • 1
    • 0029099391 scopus 로고
    • Effects of IL-12 on immune responses to microbial infections: A key mediator in regulating disease outcome
    • 1. Biron CA, Gazzinelli RT (1995) Effects of IL-12 on immune responses to microbial infections: a key mediator in regulating disease outcome. Curr Opin Immunol 7:485-496
    • (1995) Curr Opin Immunol , vol.7 , pp. 485-496
    • Biron, C.A.1    Gazzinelli, R.T.2
  • 2
    • 0030219913 scopus 로고    scopus 로고
    • To kill or to cure: Options in host defense against viral infection
    • 2. Guidotti LG, Chisari FV (1996) To kill or to cure: options in host defense against viral infection. Curr Opin Immunol 8: 478-483
    • (1996) Curr Opin Immunol , vol.8 , pp. 478-483
    • Guidotti, L.G.1    Chisari, F.V.2
  • 3
    • 0031060376 scopus 로고    scopus 로고
    • Distinct organ-dependent mechanisms for the control of murine cytomegalovirus infection by natural killer cells
    • 3. Tay CH, Welsh RM (1997) Distinct organ-dependent mechanisms for the control of murine cytomegalovirus infection by natural killer cells. J Virol 71:267-275
    • (1997) J Virol , vol.71 , pp. 267-275
    • Tay, C.H.1    Welsh, R.M.2
  • 6
    • 0024600512 scopus 로고
    • Tumour necrosis factor
    • 6. Balkwill FR (1989) Tumour necrosis factor. Br Med Bull 45:389-400
    • (1989) Br Med Bull , vol.45 , pp. 389-400
    • Balkwill, F.R.1
  • 7
  • 8
    • 0024387320 scopus 로고
    • A phase I trial of recombinant human tumor necrosis factor and interferon-γ: Effects of combination cytokine administration in vivo
    • 8. Demetri GD, Spriggs DR, Sherman ML, Arthur KA, Imamura K, Kufe DW (1989) A phase I trial of recombinant human tumor necrosis factor and interferon-γ: effects of combination cytokine administration in vivo. J Clin Oncol 7:1545-1553
    • (1989) J Clin Oncol , vol.7 , pp. 1545-1553
    • Demetri, G.D.1    Spriggs, D.R.2    Sherman, M.L.3    Arthur, K.A.4    Imamura, K.5    Kufe, D.W.6
  • 10
    • 0027738720 scopus 로고
    • Effects of recombinant tumour necrosis factor (rTNF-α) in cancer. Observations on the acute phase protein reaction and immunoglobulin synthesis after high dose recombinant TNF-α administration in isolated limb perfusions in cancer patients
    • 10. Swaak AJ, Lienard D, Schraffordt KH, Lejeune FJ, Eggermont AM (1993) Effects of recombinant tumour necrosis factor (rTNF-α) in cancer. Observations on the acute phase protein reaction and immunoglobulin synthesis after high dose recombinant TNF-α administration in isolated limb perfusions in cancer patients. Eur J Clin Invest 23:812-818
    • (1993) Eur J Clin Invest , vol.23 , pp. 812-818
    • Swaak, A.J.1    Lienard, D.2    Schraffordt, K.H.3    Lejeune, F.J.4    Eggermont, A.M.5
  • 12
    • 0027300637 scopus 로고
    • Immunotherapy of endotoxemia and septicemia
    • 12. Baumgartner JD, Glauser MP (1993) Immunotherapy of endotoxemia and septicemia. Immunobiology 187:464-477
    • (1993) Immunobiology , vol.187 , pp. 464-477
    • Baumgartner, J.D.1    Glauser, M.P.2
  • 13
    • 0028878692 scopus 로고
    • Sepsis, sepsis syndrome, and the systemic inflammatory response syndrome (SIRS). Gulliver in Laputa
    • 13. Bone RC (1995) Sepsis, sepsis syndrome, and the systemic inflammatory response syndrome (SIRS). Gulliver in Laputa. JAMA 273:155-156
    • (1995) JAMA , vol.273 , pp. 155-156
    • Bone, R.C.1
  • 14
    • 0028606246 scopus 로고
    • Antiendotoxin antibodies: A dead end?
    • 14. Cross AS (1994) Antiendotoxin antibodies: a dead end? Ann Intern Med 121:58-60
    • (1994) Ann Intern Med , vol.121 , pp. 58-60
    • Cross, A.S.1
  • 15
    • 0025999299 scopus 로고
    • Gram-negative bacterial sepsis in hospitals in the United States - Natural history in the 1980s
    • 15. Martin MA, Wenzel RP, Gorelick KJ (1991) Gram-negative bacterial sepsis in hospitals in the United States - natural history in the 1980s. Prog Clin Biol Res 367:111-119
    • (1991) Prog Clin Biol Res , vol.367 , pp. 111-119
    • Martin, M.A.1    Wenzel, R.P.2    Gorelick, K.J.3
  • 18
    • 0025003076 scopus 로고
    • Metabolic responses to cachectin/TNF. A brief review
    • 18. Tracey KJ, Cerami A (1990) Metabolic responses to cachectin/TNF. A brief review. Ann NY Acad Sci 587:325-331
    • (1990) Ann NY Acad Sci , vol.587 , pp. 325-331
    • Tracey, K.J.1    Cerami, A.2
  • 21
    • 0031879125 scopus 로고    scopus 로고
    • Soluble receptors in human disease
    • 21. Heaney ML, Golde DW (1998) Soluble receptors in human disease. J Leukoc Biol 64:135-146
    • (1998) J Leukoc Biol , vol.64 , pp. 135-146
    • Heaney, M.L.1    Golde, D.W.2
  • 22
    • 0032816365 scopus 로고    scopus 로고
    • Soluble cytokine receptors: Basic immunology and clinical applications
    • 22. Fernandez-Botran R (1999) Soluble cytokine receptors: basic immunology and clinical applications. Crit Rev Clin Lab Sci 36:165-224
    • (1999) Crit Rev Clin Lab Sci , vol.36 , pp. 165-224
    • Fernandez-Botran, R.1
  • 23
    • 0023256367 scopus 로고
    • In vivo administration of purified human interleukin-2 to patients with cancer: Development of interleukin-2 receptor positive cells and circulating soluble interleukin-2 receptors following interleukin-2 administration
    • 23. Lotze MT, Custer MC, Sharrow SO, Rubin LA, Nelson DL, Rosenberg SA (1987) In vivo administration of purified human interleukin-2 to patients with cancer: development of interleukin-2 receptor positive cells and circulating soluble interleukin-2 receptors following interleukin-2 administration. Cancer Res 47:2188-2195
    • (1987) Cancer Res , vol.47 , pp. 2188-2195
    • Lotze, M.T.1    Custer, M.C.2    Sharrow, S.O.3    Rubin, L.A.4    Nelson, D.L.5    Rosenberg, S.A.6
  • 24
    • 0024391574 scopus 로고
    • Serum levels of the low-affinity interleukin-2 receptor molecule (TAC) during IL-2 therapy reflect systemic lymphoid mass activation
    • 24. Voss SD, Hank JA, Nobis CA, Fisch P, Sosman JA, Sondel PM (1989) Serum levels of the low-affinity interleukin-2 receptor molecule (TAC) during IL-2 therapy reflect systemic lymphoid mass activation. Cancer Immunol Immunother 29: 261-269
    • (1989) Cancer Immunol Immunother , vol.29 , pp. 261-269
    • Voss, S.D.1    Hank, J.A.2    Nobis, C.A.3    Fisch, P.4    Sosman, J.A.5    Sondel, P.M.6
  • 25
    • 0026058710 scopus 로고
    • Soluble cytokine receptors: Their role in immunoregulation
    • 25. Fernandez-Botran R (1991) Soluble cytokine receptors: their role in immunoregulation. FASEB J 5:2567-2574
    • (1991) FASEB J , vol.5 , pp. 2567-2574
    • Fernandez-Botran, R.1
  • 26
    • 0029180522 scopus 로고
    • Inhibiting the effects of cytokines in human diseases
    • 26. Arend WP (1995) Inhibiting the effects of cytokines in human diseases. Adv Intern Med 40:365-394
    • (1995) Adv Intern Med , vol.40 , pp. 365-394
    • Arend, W.P.1
  • 29
    • 0026516744 scopus 로고
    • Stabilization of the bioactivity of tumor necrosis factor by its soluble receptors
    • 29. Aderka D, Engelmann H, Maor Y, Brakebusch C, Wallach D (1992) Stabilization of the bioactivity of tumor necrosis factor by its soluble receptors. J Exp Med 175:323-329
    • (1992) J Exp Med , vol.175 , pp. 323-329
    • Aderka, D.1    Engelmann, H.2    Maor, Y.3    Brakebusch, C.4    Wallach, D.5
  • 30
    • 0032168152 scopus 로고    scopus 로고
    • Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway
    • 30. Heinrich PC, Behrmann I, Muller-Newen G, Schaper F, Graeve L (1998) Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway. Biochem J 334:297-314
    • (1998) Biochem J , vol.334 , pp. 297-314
    • Heinrich, P.C.1    Behrmann, I.2    Muller-Newen, G.3    Schaper, F.4    Graeve, L.5
  • 31
    • 0033083887 scopus 로고    scopus 로고
    • Cytokine pleiotropy and redundancy-gp130 cytokines in human implantation
    • 31. Sanchez-Cuenca J, Martin JC, Pellicer A, Simon C (1999) Cytokine pleiotropy and redundancy-gp130 cytokines in human implantation. Immunol Today 20:57-59
    • (1999) Immunol Today , vol.20 , pp. 57-59
    • Sanchez-Cuenca, J.1    Martin, J.C.2    Pellicer, A.3    Simon, C.4
  • 32
    • 0029932769 scopus 로고    scopus 로고
    • Purification and characterization of the soluble interleukin-6 receptor from human plasma and identification of an isoform generated through alternative splicing
    • 32. Muller-Newen G, Kohne C, Keul R, Hemmann U, Muller-Esterl W, Wijdenes J, Brakenhoff JP, Hart MH, Heinrich PC (1996) Purification and characterization of the soluble interleukin-6 receptor from human plasma and identification of an isoform generated through alternative splicing. Eur J Biochem 236:837-842
    • (1996) Eur J Biochem , vol.236 , pp. 837-842
    • Muller-Newen, G.1    Kohne, C.2    Keul, R.3    Hemmann, U.4    Muller-Esterl, W.5    Wijdenes, J.6    Brakenhoff, J.P.7    Hart, M.H.8    Heinrich, P.C.9
  • 38
    • 0027320144 scopus 로고
    • The role of human autoantibodies against γ-interferon
    • 38. Turano A, Caruso A (1993) The role of human autoantibodies against γ-Interferon. J Antimicrob Chemother 32 [Suppl A]: 99-105
    • (1993) J Antimicrob Chemother , vol.32 , Issue.SUPPL. A , pp. 99-105
    • Turano, A.1    Caruso, A.2
  • 39
    • 0027317927 scopus 로고
    • Neutrophil attractant protein-1 and monocyte chemoattractant protein-1 in human serum. Effects of intravenous lipopolysaccharide on free attractants, specific IgG autoantibodies and immune complexes
    • 39. Sylvester I, Suffredini AF, Boujoukos AJ, Martich GD, Danner RL, Yoshimura T, Leonard EJ (1993) Neutrophil attractant protein-1 and monocyte chemoattractant protein-1 in human serum. Effects of intravenous lipopolysaccharide on free attractants, specific IgG autoantibodies and immune complexes. J Immunol 151:3292-3298
    • (1993) J Immunol , vol.151 , pp. 3292-3298
    • Sylvester, I.1    Suffredini, A.F.2    Boujoukos, A.J.3    Martich, G.D.4    Danner, R.L.5    Yoshimura, T.6    Leonard, E.J.7
  • 40
    • 0029398646 scopus 로고
    • Interleukin-2 binding proteins in sera from normal subjects and multiple sclerosis patients
    • 40. Trotter JL, Damico CA, Trotter AL, Collins KG, Cross AH (1995) Interleukin-2 binding proteins in sera from normal subjects and multiple sclerosis patients. Neurology 45:1971-1974
    • (1995) Neurology , vol.45 , pp. 1971-1974
    • Trotter, J.L.1    Damico, C.A.2    Trotter, A.L.3    Collins, K.G.4    Cross, A.H.5
  • 41
    • 0029862306 scopus 로고    scopus 로고
    • Nerve growth factor (NGF) autoantibodies and NGF in the synovial fluid: Implications in spondylarthropathies
    • 41. Dicou E, Perrot S, Menkes CJ, Masson C, Nerriere V (1996) Nerve growth factor (NGF) autoantibodies and NGF in the synovial fluid: implications in spondylarthropathies. Autoimmunity 24:1-9
    • (1996) Autoimmunity , vol.24 , pp. 1-9
    • Dicou, E.1    Perrot, S.2    Menkes, C.J.3    Masson, C.4    Nerriere, V.5
  • 42
    • 0030727797 scopus 로고    scopus 로고
    • Naturally occurring and therapy-induced antibodies to human granulocyte colony-stimulating factor (G-CSF) in human serum
    • 42. Laricchia-Robbio L, Moscato S, Genua A, Liberati AM, Revoltella RP (1997) Naturally occurring and therapy-induced antibodies to human granulocyte colony-stimulating factor (G-CSF) in human serum. J Cell Physiol 173:219-226
    • (1997) J Cell Physiol , vol.173 , pp. 219-226
    • Laricchia-Robbio, L.1    Moscato, S.2    Genua, A.3    Liberati, A.M.4    Revoltella, R.P.5
  • 43
    • 0025225511 scopus 로고
    • Distribution and characterization of autoantibodies to interleukin 1α in normal human sera
    • 43. Svenson M, Bagge HM, Bendtzen K (1990) Distribution and characterization of autoantibodies to interleukin 1α in normal human sera. Scand J Immunol 32:695-701
    • (1990) Scand J Immunol , vol.32 , pp. 695-701
    • Svenson, M.1    Bagge, H.M.2    Bendtzen, K.3
  • 44
    • 0030823544 scopus 로고    scopus 로고
    • Increased in vivo antibody activity against interferon-α, interleukin-1α, and interleukin-6 after high-dose Ig therapy
    • 44. Ross C, Svenson M, Nielsen H, Lundsgaard C, Hansen MB, Bendtzen K (1997) Increased in vivo antibody activity against interferon-α, interleukin-1α, and interleukin-6 after high-dose Ig therapy. Blood 90:2376-2380
    • (1997) Blood , vol.90 , pp. 2376-2380
    • Ross, C.1    Svenson, M.2    Nielsen, H.3    Lundsgaard, C.4    Hansen, M.B.5    Bendtzen, K.6
  • 45
    • 0028960469 scopus 로고
    • High avidity IFN-neutralizing antibodies in pharmaceutically prepared human IgG
    • 45. Ross C, Svenson M, Hansen MB, Vejlsgaard GL, Bendtzen K (1995) High avidity IFN-neutralizing antibodies in pharmaceutically prepared human IgG. J Clin Invest 95:1974-1978
    • (1995) J Clin Invest , vol.95 , pp. 1974-1978
    • Ross, C.1    Svenson, M.2    Hansen, M.B.3    Vejlsgaard, G.L.4    Bendtzen, K.5
  • 47
    • 0013668787 scopus 로고    scopus 로고
    • 47. Special issue on anti-cytokine antibodies (1997) Biotherapy 10
    • (1997) Biotherapy , pp. 10
  • 49
    • 0026449575 scopus 로고
    • Anti-cytokine strategies
    • 49. Dinarello CA (1992) Anti-cytokine strategies. Eur Cytokine Netw 3:7-17
    • (1992) Eur Cytokine Netw , vol.3 , pp. 7-17
    • Dinarello, C.A.1
  • 50
    • 0026503113 scopus 로고
    • Therapeutic potential of cytokine manipulation
    • 50. Henderson B, Blake S (1992) Therapeutic potential of cytokine manipulation. Trends Pharmacol Sci 13:145-152
    • (1992) Trends Pharmacol Sci , vol.13 , pp. 145-152
    • Henderson, B.1    Blake, S.2
  • 51
    • 0028986977 scopus 로고
    • Cytokine-binding proteins: Stimulating antagonists
    • 51. Klein B, Brailly H (1995) Cytokine-binding proteins: stimulating antagonists. Immunol Today 16:216-220
    • (1995) Immunol Today , vol.16 , pp. 216-220
    • Klein, B.1    Brailly, H.2
  • 53
    • 0027879413 scopus 로고
    • Overall interleukin-6 production exceeds 7 mg/day in multiple myeloma complicated by sepsis
    • 53. Lu ZY, Brailly H, Rossi JF, Wijdenes J, Bataille R, Klein B (1993) Overall interleukin-6 production exceeds 7 mg/day in multiple myeloma complicated by sepsis. Cytokine 5:578-582
    • (1993) Cytokine , vol.5 , pp. 578-582
    • Lu, Z.Y.1    Brailly, H.2    Rossi, J.F.3    Wijdenes, J.4    Bataille, R.5    Klein, B.6
  • 54
    • 0027402917 scopus 로고
    • Treatment of severe rheumatoid arthritis by anti-interleukin 6 monoclonal antibody
    • 54. Wendling D, Racadot E, Wijdenes J (1993) Treatment of severe rheumatoid arthritis by anti-interleukin 6 monoclonal antibody. J Rheumatol 20:259-262
    • (1993) J Rheumatol , vol.20 , pp. 259-262
    • Wendling, D.1    Racadot, E.2    Wijdenes, J.3
  • 56
    • 0028046237 scopus 로고
    • Administration of an anti-interleukin-6 monoclonal antibody to patients with acquired immunodeficiency syndrome and lymphoma: Effect on lymphoma growth and on B clinical symptoms
    • 56. Emilie D, Wijdenes J, Gisselbrecht C, Jarrousse B, Billaud E, Blay JY, Gabarre J, Gaillard JP, Brochier J, Raphael M (1994) Administration of an anti-interleukin-6 monoclonal antibody to patients with acquired immunodeficiency syndrome and lymphoma: effect on lymphoma growth and on B clinical symptoms. Blood 84:2472-2479
    • (1994) Blood , vol.84 , pp. 2472-2479
    • Emilie, D.1    Wijdenes, J.2    Gisselbrecht, C.3    Jarrousse, B.4    Billaud, E.5    Blay, J.Y.6    Gabarre, J.7    Gaillard, J.P.8    Brochier, J.9    Raphael, M.10
  • 58
    • 0028900662 scopus 로고
    • Pharmacokinetic study of anti-interleukin-6 (IL-6) therapy with monoclonal antibodies: Enhancement of IL-6 clearance by cocktails of anti-IL-6 antibodies
    • 58. Montero-Julian FA, Klein B, Gautherot E, Brailly H (1995) Pharmacokinetic study of anti-interleukin-6 (IL-6) therapy with monoclonal antibodies: enhancement of IL-6 clearance by cocktails of anti-IL-6 antibodies. Blood 85:917-924
    • (1995) Blood , vol.85 , pp. 917-924
    • Montero-Julian, F.A.1    Klein, B.2    Gautherot, E.3    Brailly, H.4
  • 59
    • 0027320006 scopus 로고
    • Enhancement of the biologic effects of interleukin-3 in vivo by anti-interleukin-3 antibodies
    • 59. Jones AT, Ziltener HJ (1993) Enhancement of the biologic effects of interleukin-3 in vivo by anti-interleukin-3 antibodies. Blood 82:1133-1141
    • (1993) Blood , vol.82 , pp. 1133-1141
    • Jones, A.T.1    Ziltener, H.J.2
  • 60
    • 0027239843 scopus 로고
    • Anti-cytokine antibodies as carrier proteins. Prolongation of in vivo effects of exogenous cytokines by injection of cytokine-anti-cytokine antibody complexes
    • 60. Finkelman FD, Madden KB, Morris SC, Holmes JM, Boiani N, Katona IM, Maliszewski CR (1993) Anti-cytokine antibodies as carrier proteins. Prolongation of in vivo effects of exogenous cytokines by injection of cytokine-anti-cytokine antibody complexes. J Immunol 151:1235-1244
    • (1993) J Immunol , vol.151 , pp. 1235-1244
    • Finkelman, F.D.1    Madden, K.B.2    Morris, S.C.3    Holmes, J.M.4    Boiani, N.5    Katona, I.M.6    Maliszewski, C.R.7
  • 66
    • 0027465066 scopus 로고
    • A case for cytokines as effector molecules in the resolution of virus infection
    • 66. Ramsay AJ, Ruby J, Ramshaw IA (1993) A case for cytokines as effector molecules in the resolution of virus infection. Immunol Today 14:155-157
    • (1993) Immunol Today , vol.14 , pp. 155-157
    • Ramsay, A.J.1    Ruby, J.2    Ramshaw, I.A.3
  • 67
  • 68
    • 0032476684 scopus 로고    scopus 로고
    • Protective heterologous antiviral immunity and enhanced immunopathogenesis mediated by memory T cell populations
    • 68. Selin LK, Varga SM, Wong IC, Welsh RM (1998) Protective heterologous antiviral immunity and enhanced immunopathogenesis mediated by memory T cell populations. J Exp Med 188:1705-1715
    • (1998) J Exp Med , vol.188 , pp. 1705-1715
    • Selin, L.K.1    Varga, S.M.2    Wong, I.C.3    Welsh, R.M.4
  • 70
    • 0033961476 scopus 로고    scopus 로고
    • + T cells can be distinguished by their cytokine profiles and phenotypic markers
    • + T cells can be distinguished by their cytokine profiles and phenotypic markers. J Immunol 164:208-216
    • (2000) J Immunol , vol.164 , pp. 208-216
    • Slifka, M.K.1    Whitton, J.L.2
  • 71
    • 0026475049 scopus 로고
    • Selective and differential binding of interleukin (IL)-1α, IL-1β, IL-2 and IL-6 to glycosaminoglycans
    • 71. Ramsden L, Rider CC (1992) Selective and differential binding of interleukin (IL)-1α, IL-1β, IL-2 and IL-6 to glycosaminoglycans. Eur J Immunol 22:3027-3031
    • (1992) Eur J Immunol , vol.22 , pp. 3027-3031
    • Ramsden, L.1    Rider, C.C.2
  • 72
    • 0027408343 scopus 로고
    • Proteoglycans on endothelial cells present adhesion-inducing cytokines to leukocytes
    • 72. Tanaka Y, Adams DH, Shaw S (1993) Proteoglycans on endothelial cells present adhesion-inducing cytokines to leukocytes. Immunol Today 14:111-115
    • (1993) Immunol Today , vol.14 , pp. 111-115
    • Tanaka, Y.1    Adams, D.H.2    Shaw, S.3
  • 73
    • 0023928595 scopus 로고
    • Heparan sulphate bound growth factors: A mechanism for stromal cell mediated haemopoiesis
    • 73. Roberts R, Gallagher J, Spooncer E, Allen TD, Bloomfield F, Dexter TM (1988) Heparan sulphate bound growth factors: a mechanism for stromal cell mediated haemopoiesis. Nature 332:376-378
    • (1988) Nature , vol.332 , pp. 376-378
    • Roberts, R.1    Gallagher, J.2    Spooncer, E.3    Allen, T.D.4    Bloomfield, F.5    Dexter, T.M.6
  • 74
    • 0030060311 scopus 로고    scopus 로고
    • Interplay of T cells and cytokines in the context of enzymatically modified extracellular matrix
    • 74. Gilat D, Cahalon L, Hershkoviz R, Lider O (1996) Interplay of T cells and cytokines in the context of enzymatically modified extracellular matrix. Immunol Today 17:16-20
    • (1996) Immunol Today , vol.17 , pp. 16-20
    • Gilat, D.1    Cahalon, L.2    Hershkoviz, R.3    Lider, O.4
  • 75
    • 0028105915 scopus 로고
    • Functional interactions of fibronectin and TNFα: A paradigm of physiological linkage between cytokines and extracellular matrix moieties
    • 75. Cahalon L, Hershkoviz R, Gilat D, Miller A, Akiyama SK, Yamada KM, Lider O (1994) Functional interactions of fibronectin and TNFα: a paradigm of physiological linkage between cytokines and extracellular matrix moieties. Cell Adhes Commun 2:269-273
    • (1994) Cell Adhes Commun , vol.2 , pp. 269-273
    • Cahalon, L.1    Hershkoviz, R.2    Gilat, D.3    Miller, A.4    Akiyama, S.K.5    Yamada, K.M.6    Lider, O.7
  • 78
    • 0030882762 scopus 로고    scopus 로고
    • Taming TNF: Strategies to restrain this proinflammatory cytokine
    • 78. Eigler A, Sinha B, Hartmann G, Endres S (1997) Taming TNF: strategies to restrain this proinflammatory cytokine. Immunol Today 18:487-492
    • (1997) Immunol Today , vol.18 , pp. 487-492
    • Eigler, A.1    Sinha, B.2    Hartmann, G.3    Endres, S.4
  • 79
    • 0028244816 scopus 로고
    • Tumor necrosis factor: A pleiotropic cytokine and therapeutic target
    • 79. Tracey KJ, Cerami A (1994) Tumor necrosis factor: a pleiotropic cytokine and therapeutic target. Annu Rev Med 45: 491-503
    • (1994) Annu Rev Med , vol.45 , pp. 491-503
    • Tracey, K.J.1    Cerami, A.2
  • 80
    • 0024950718 scopus 로고
    • Tumour necrosis factor: Clinical relevance
    • 80. Jones AL, Selby P (1989) Tumour necrosis factor: clinical relevance. Cancer Surv 8:817-836
    • (1989) Cancer Surv , vol.8 , pp. 817-836
    • Jones, A.L.1    Selby, P.2
  • 81
    • 0026717674 scopus 로고
    • The pathophysiology of tumor necrosis factors
    • 81. Vassalli P (1992) The pathophysiology of tumor necrosis factors. Annu Rev Immunol 10:411-452
    • (1992) Annu Rev Immunol , vol.10 , pp. 411-452
    • Vassalli, P.1


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