-
1
-
-
4344578534
-
The cochaperone HspBP1 inhibits the CHIP ubiquitin ligase and stimulates the maturation of the cystic fibrosis transmembrane conductance regulator
-
Alberti S, Böhse K, Arndt V, Schmitz A, Höhfeld J. 2004. The cochaperone HspBP1 inhibits the CHIP ubiquitin ligase and stimulates the maturation of the cystic fibrosis transmembrane conductance regulator. Mol Biol Cell 15: 4003-4010.
-
(2004)
Mol Biol Cell
, vol.15
, pp. 4003-4010
-
-
Alberti, S.1
Böhse, K.2
Arndt, V.3
Schmitz, A.4
Höhfeld, J.5
-
2
-
-
2942580461
-
CFTR and chaperones
-
Amaral MD. 2004. CFTR and chaperones. J Mol Neurosci 23: 41-47.
-
(2004)
J Mol Neurosci
, vol.23
, pp. 41-47
-
-
Amaral, M.D.1
-
3
-
-
33745091537
-
Therapy through chaperones: Sense or antisense? Cystic fibrosis as a model disease
-
Amaral MD. 2006. Therapy through chaperones: Sense or antisense? Cystic fibrosis as a model disease. J Inherit Metab Dis 29: 477-487.
-
(2006)
J Inherit Metab Dis
, vol.29
, pp. 477-487
-
-
Amaral, M.D.1
-
4
-
-
34347333381
-
Molecular targeting of CFTR as a therapeutic approach to cystic fibrosis
-
Amaral MD, Kunzelmann K. 2007. Molecular targeting of CFTR as a therapeutic approach to cystic fibrosis. Trends Pharmacol Sci 28: 334-3341.
-
(2007)
Trends Pharmacol Sci
, vol.28
, pp. 334-3341
-
-
Amaral, M.D.1
Kunzelmann, K.2
-
5
-
-
77952112425
-
IKKγ protein is a target of BAG3 regulatory activity in human tumor growth
-
Ammirante M, Rosati A, Arra C, Festa M, Basile A, Falco A, Pascale M, d'Avenia M, Marzullo L, Belisario MA, Barbieri A, Giudice A, Chiappetta G, Vuttariello E, Monaco M, Bonelli P, Salvatore G, Di Benedetto M, Deshmane S, Khalili K, Turco MC, Leone A. 2010. IKKγ protein is a target of BAG3 regulatory activity in human tumor growth. Proc Natl Acad Sci USA 107: 7497-7502.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 7497-7502
-
-
Ammirante, M.1
Rosati, A.2
Arra, C.3
Festa, M.4
Basile, A.5
Falco, A.6
Pascale, M.7
d'Avenia, M.8
Marzullo, L.9
Belisario, M.A.10
Barbieri, A.11
Giudice, A.12
Chiappetta, G.13
Vuttariello, E.14
Monaco, M.15
Bonelli, P.16
Salvatore, G.17
Di Benedetto, M.18
Deshmane, S.19
Khalili, K.20
Turco, M.C.21
Leone, A.22
more..
-
6
-
-
34547557698
-
Correctors of protein trafficking defects identified by a novel high-throughput screening assay
-
Carlile GW, Robert R, Zhang D, Teske KA, Luo Y, Hanrahan JW, Thomas DY. 2007. Correctors of protein trafficking defects identified by a novel high-throughput screening assay. ChemBioChem 8: 1012-1020.
-
(2007)
ChemBioChem
, vol.8
, pp. 1012-1020
-
-
Carlile, G.W.1
Robert, R.2
Zhang, D.3
Teske, K.A.4
Luo, Y.5
Hanrahan, J.W.6
Thomas, D.Y.7
-
8
-
-
79957946294
-
Managing cystic fibrosis: Strategies that increase life expectancy and improve quality of life
-
Cohen-Cymberknoh M, Shoseyov D, Kerem E. 2011. Managing cystic fibrosis: Strategies that increase life expectancy and improve quality of life. Am J Respir Crit Care Med 183: 1463-1471.
-
(2011)
Am J Respir Crit Care Med
, vol.183
, pp. 1463-1471
-
-
Cohen-Cymberknoh, M.1
Shoseyov, D.2
Kerem, E.3
-
9
-
-
33645130994
-
Cystic fibrosis since 1938
-
Davis PB. 2006. Cystic fibrosis since 1938. Am J Respir Crit Care Med 173: 475-482.
-
(2006)
Am J Respir Crit Care Med
, vol.173
, pp. 475-482
-
-
Davis, P.B.1
-
10
-
-
33747015789
-
Quinolizidine alkaloids with Anti-HBV activity from Sophora tonkinensis
-
Ding PL, Huang H, Zhou P, Chen DF. 2006. Quinolizidine alkaloids with Anti-HBV activity from Sophora tonkinensis. Planta Med 72: 854-856.
-
(2006)
Planta Med
, vol.72
, pp. 854-856
-
-
Ding, P.L.1
Huang, H.2
Zhou, P.3
Chen, D.F.4
-
11
-
-
0042208135
-
CAIR-1/BAG-3 abrogates heat shock protein-70 chaperone complex-mediated protein degradation
-
Doong H, Rizzo K, Fang S, Kulpa V, Weissman AM, Kohn EC. 2003. CAIR-1/BAG-3 abrogates heat shock protein-70 chaperone complex-mediated protein degradation. J Biol Chem 278: 28490-28500.
-
(2003)
J Biol Chem
, vol.278
, pp. 28490-28500
-
-
Doong, H.1
Rizzo, K.2
Fang, S.3
Kulpa, V.4
Weissman, A.M.5
Kohn, E.C.6
-
12
-
-
0036115199
-
Calcium-pump inhibitors induce functional surface expression of Delta F508-CFTR protein in cystic fibrosis epithelial cells
-
Egan ME, Glöckner-Pagel J, Ambrose CA, Cahill PA, Pappoe L, Balamuth N, Cho E, Canny S, Wagner CA, Geibel J, Caplan MJ. 2002. Calcium-pump inhibitors induce functional surface expression of Delta F508-CFTR protein in cystic fibrosis epithelial cells. Nat Med 8: 485-492.
-
(2002)
Nat Med
, vol.8
, pp. 485-492
-
-
Egan, M.E.1
Glöckner-Pagel, J.2
Ambrose, C.A.3
Cahill, P.A.4
Pappoe, L.5
Balamuth, N.6
Cho, E.7
Canny, S.8
Wagner, C.A.9
Geibel, J.10
Caplan, M.J.11
-
13
-
-
79851474442
-
Design and synthesis of Oxymatrine analogues overcoming drug resistence in hepatitis B virus, through targeting host heat stress cognate 70
-
Gao LM, Han YX, Wang YP, Li YH, Shan YQ, Li X, Peng ZG, Bi CW, Zhang T, Du NN, Jiang JD, Song DQ. 2011. Design and synthesis of Oxymatrine analogues overcoming drug resistence in hepatitis B virus, through targeting host heat stress cognate 70. J Med Chem 54: 869-876.
-
(2011)
J Med Chem
, vol.54
, pp. 869-876
-
-
Gao, L.M.1
Han, Y.X.2
Wang, Y.P.3
Li, Y.H.4
Shan, Y.Q.5
Li, X.6
Peng, Z.G.7
Bi, C.W.8
Zhang, T.9
Du, N.N.10
Jiang, J.D.11
Song, D.Q.12
-
14
-
-
70350236409
-
Mechanisms for rescue of correctable folding defects in CFTRDelta F508
-
Grove DE, Rosser MFN, Ren HY, Naren AP, Cyr DM. 2009. Mechanisms for rescue of correctable folding defects in CFTRDelta F508. Mol Biol Cell 20: 4059-4069.
-
(2009)
Mol Biol Cell
, vol.20
, pp. 4059-4069
-
-
Grove, D.E.1
Rosser, M.F.N.2
Ren, H.Y.3
Naren, A.P.4
Cyr, D.M.5
-
15
-
-
78649775607
-
The primary folding defect and rescue of ΔF508 CFTR emerge during translation of the mutant domain
-
Hoelen H, Kleizen B, Schmidt A, Richardson J, Charitou P, Thomas PJ, Braakman I. 2010. The primary folding defect and rescue of ΔF508 CFTR emerge during translation of the mutant domain. PLoS One 5: e15458.
-
(2010)
PLoS One
, vol.5
-
-
Hoelen, H.1
Kleizen, B.2
Schmidt, A.3
Richardson, J.4
Charitou, P.5
Thomas, P.J.6
Braakman, I.7
-
16
-
-
78449313543
-
Synthesis and in vitro inhibitory activity of matrine derivatives towards pro-inflammatory cytokines
-
Hu H, Wang S, Zhang C, Wang L, Ding L, Zhang J, Wu Q. 2010. Synthesis and in vitro inhibitory activity of matrine derivatives towards pro-inflammatory cytokines. Bioorg Med Chem Lett 20: 7537-7539.
-
(2010)
Bioorg Med Chem Lett
, vol.20
, pp. 7537-7539
-
-
Hu, H.1
Wang, S.2
Zhang, C.3
Wang, L.4
Ding, L.5
Zhang, J.6
Wu, Q.7
-
17
-
-
0031853136
-
Partial restoration of cAMP-stimulated CFTR chloride channel activity in DeltaF508cells by deoxyspergualin
-
Jiang C, Fang SL, Xiao YF, O'Connor SP, Nadler SG, Lee DW, Jefferson DM, Kaplan JM, Smith AE, Cheng SH. 1998. Partial restoration of cAMP-stimulated CFTR chloride channel activity in DeltaF508cells by deoxyspergualin. Am J Physiol 275: C171-C178.
-
(1998)
Am J Physiol
, vol.275
-
-
Jiang, C.1
Fang, S.L.2
Xiao, Y.F.3
O'Connor, S.P.4
Nadler, S.G.5
Lee, D.W.6
Jefferson, D.M.7
Kaplan, J.M.8
Smith, A.E.9
Cheng, S.H.10
-
18
-
-
78651264296
-
Small molecule correctors of F508del-CFTR discovered by structure-based virtual screening
-
Kalid O, Mense M, Fischman S, Shitrit A, Bibler H, Ben-Zeev E, Schutz N, Pedemonte N, Thomas PJ, Bridges RJ, Wetmore DR, Marantz Y, Senderowitz H. 2010. Small molecule correctors of F508del-CFTR discovered by structure-based virtual screening. J Comput Aided Mol Des 24: 971-991.
-
(2010)
J Comput Aided Mol Des
, vol.24
, pp. 971-991
-
-
Kalid, O.1
Mense, M.2
Fischman, S.3
Shitrit, A.4
Bibler, H.5
Ben-Zeev, E.6
Schutz, N.7
Pedemonte, N.8
Thomas, P.J.9
Bridges, R.J.10
Wetmore, D.R.11
Marantz, Y.12
Senderowitz, H.13
-
19
-
-
77956237958
-
A chemical corrector modifies the channel function of F508del-CFTR
-
Kim Chiaw P, Wellhauser L, Huan LJ, Ramjeesingh M, Bear CE. 2010. A chemical corrector modifies the channel function of F508del-CFTR. Mol Pharmacol 78: 411-418.
-
(2010)
Mol Pharmacol
, vol.78
, pp. 411-418
-
-
Kim Chiaw, P.1
Wellhauser, L.2
Huan, L.J.3
Ramjeesingh, M.4
Bear, C.E.5
-
20
-
-
12344254731
-
Anti-HBV effect of liposome-encapsulated matrine in vitro and in vivo
-
Li CQ, Zhu YT, Zhang FX, Fu LC, Li XH, Cheng Y, Li XY. 2005. Anti-HBV effect of liposome-encapsulated matrine in vitro and in vivo. World J Gastroenterol 11: 426-428.
-
(2005)
World J Gastroenterol
, vol.11
, pp. 426-428
-
-
Li, C.Q.1
Zhu, Y.T.2
Zhang, F.X.3
Fu, L.C.4
Li, X.H.5
Cheng, Y.6
Li, X.Y.7
-
21
-
-
69949118050
-
Antiarrhythmic properties of long-term treatment with Matrine in arrhythmic rat induced by coronary ligation
-
Li X, Chu W, Liu J, Xue X, Lu Y, Shan H, Yang B. 2009. Antiarrhythmic properties of long-term treatment with Matrine in arrhythmic rat induced by coronary ligation. Biol Pharm Bull 32: 1521-1526.
-
(2009)
Biol Pharm Bull
, vol.32
, pp. 1521-1526
-
-
Li, X.1
Chu, W.2
Liu, J.3
Xue, X.4
Lu, Y.5
Shan, H.6
Yang, B.7
-
22
-
-
0032401771
-
Perturbation of Hsp90 interaction with nascent CFTR prevents its maturation and accelerates its degradation by the proteasome
-
Loo MA, Jensen TJ, Cui L, Hou Y, Chang XB, Riordan JR. 1998. Perturbation of Hsp90 interaction with nascent CFTR prevents its maturation and accelerates its degradation by the proteasome. EMBO J 7: 6879-6887.
-
(1998)
EMBO J
, vol.7
, pp. 6879-6887
-
-
Loo, M.A.1
Jensen, T.J.2
Cui, L.3
Hou, Y.4
Chang, X.B.5
Riordan, J.R.6
-
23
-
-
0033559258
-
The Hdj-2/Hsc70 chaperone pair facilitates early steps in CFTR biogenesis
-
Meacham GC, Lu Z, King S, Sorscher E, Tousson A, Cyr DM. 1999. The Hdj-2/Hsc70 chaperone pair facilitates early steps in CFTR biogenesis. EMBO J 18: 1492-1505.
-
(1999)
EMBO J
, vol.18
, pp. 1492-1505
-
-
Meacham, G.C.1
Lu, Z.2
King, S.3
Sorscher, E.4
Tousson, A.5
Cyr, D.M.6
-
24
-
-
0021061819
-
Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
-
Mosmann T. 1983. Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays. J Immunol Methods 65: 55-63.
-
(1983)
J Immunol Methods
, vol.65
, pp. 55-63
-
-
Mosmann, T.1
-
26
-
-
0742270642
-
Delta F508 CFTR pool in the endoplasmic reticulum is increased by calnexin overexpression
-
Okiyoneda T, Harada K, Takeya M, Yamahira K, Wada I, Shuto T, Suico MA, Hashimoto Y, Kai H. 2004. Delta F508 CFTR pool in the endoplasmic reticulum is increased by calnexin overexpression. Mol Biol Cell 15: 563-574.
-
(2004)
Mol Biol Cell
, vol.15
, pp. 563-574
-
-
Okiyoneda, T.1
Harada, K.2
Takeya, M.3
Yamahira, K.4
Wada, I.5
Shuto, T.6
Suico, M.A.7
Hashimoto, Y.8
Kai, H.9
-
27
-
-
77955607650
-
Peripheral protein quality control removes unfolded CFTR from the plasma membrane
-
Okiyoneda T, Barrière H, Bagdàny M, Rabeh WM, Du K, Hohfeld J, Young JC, Lukacs GL. 2010. Peripheral protein quality control removes unfolded CFTR from the plasma membrane. Science 329: 805-810.
-
(2010)
Science
, vol.329
, pp. 805-810
-
-
Okiyoneda, T.1
Barrière, H.2
Bagdàny, M.3
Rabeh, W.M.4
Du, K.5
Hohfeld, J.6
Young, J.C.7
Lukacs, G.L.8
-
28
-
-
24644464284
-
Small-molecule correctors of defective deltaF508-CFTR cellular processing identified by high-throughput screening
-
Pedemonte N, Lukacs GL, Du K, Caci E, Zegarra-Moran O, Galietta LJ, Verkman AS. 2005. Small-molecule correctors of defective deltaF508-CFTR cellular processing identified by high-throughput screening. J Clin Investig 115: 2564-2571.
-
(2005)
J Clin Investig
, vol.115
, pp. 2564-2571
-
-
Pedemonte, N.1
Lukacs, G.L.2
Du, K.3
Caci, E.4
Zegarra-Moran, O.5
Galietta, L.J.6
Verkman, A.S.7
-
29
-
-
34347242438
-
Structure-activity relationship of 1,4-dihydropyridines as potentiators of the CFTR chloride channel
-
Pedemonte N, Boido D, Moran O, Giampieri M, Mazzei M, Ravazzolo R, Galietta LJV. 2007. Structure-activity relationship of 1, 4-dihydropyridines as potentiators of the CFTR chloride channel. Mol Pharmacol 72: 197-207.
-
(2007)
Mol Pharmacol
, vol.72
, pp. 197-207
-
-
Pedemonte, N.1
Boido, D.2
Moran, O.3
Giampieri, M.4
Mazzei, M.5
Ravazzolo, R.6
Galietta, L.J.V.7
-
30
-
-
77956641825
-
Small molecular compounds that inhibit hepatitis C virus replication through destabilizing heat shock cognate 70 messenger RNA
-
Peng ZG, Fan B, Du NN, Wang YP, Gao LM, Li YH, Liu F, You XF, Han YX, Zhao ZY, Cen S, Li JR, Song DQ, Jiang JD. 2010. Small molecular compounds that inhibit hepatitis C virus replication through destabilizing heat shock cognate 70 messenger RNA. Hepatology 52: 845-853.
-
(2010)
Hepatology
, vol.52
, pp. 845-853
-
-
Peng, Z.G.1
Fan, B.2
Du, N.N.3
Wang, Y.P.4
Gao, L.M.5
Li, Y.H.6
Liu, F.7
You, X.F.8
Han, Y.X.9
Zhao, Z.Y.10
Cen, S.11
Li, J.R.12
Song, D.Q.13
Jiang, J.D.14
-
31
-
-
66849089934
-
Cystic fibrosis: Pathogenesis and future treatment strategies
-
Ratjen FA. 2009. Cystic fibrosis: Pathogenesis and future treatment strategies. Respiratory Care 54: 595-605.
-
(2009)
Respiratory Care
, vol.54
, pp. 595-605
-
-
Ratjen, F.A.1
-
32
-
-
50649123290
-
CFTR function and prospects for therapy
-
Riordan JR. 2008. CFTR function and prospects for therapy. Annu Rev Biochem 77: 701-726.
-
(2008)
Annu Rev Biochem
, vol.77
, pp. 701-726
-
-
Riordan, J.R.1
-
33
-
-
0024424270
-
Identification of the cystic fibrosis gene: Cloning and characterization of complementary DNA
-
Riordan JR, Rommens JM, Kerem B, Alon N, Rozmahel R, Grzelczak Z, Zielenski J, Lok S, Plavsic N, Chou JL, Drumm ML, Ianuzzi MC, Collins FS, Tsui LC. 1989. Identification of the cystic fibrosis gene: Cloning and characterization of complementary DNA. Science 245: 1066-1073.
-
(1989)
Science
, vol.245
, pp. 1066-1073
-
-
Riordan, J.R.1
Rommens, J.M.2
Kerem, B.3
Alon, N.4
Rozmahel, R.5
Grzelczak, Z.6
Zielenski, J.7
Lok, S.8
Plavsic, N.9
Chou, J.L.10
Drumm, M.L.11
Ianuzzi, M.C.12
Collins, F.S.13
Tsui, L.C.14
-
34
-
-
34447104604
-
Apoptosis inhibition in cancer cells: A novel molecular pathway that involves BAG3 protein
-
Rosati A, Ammirante M, Gentilella A, Basile A, Festa M, Pascale M, Marzullo L, Belisario MA, Tosco A, Franceschelli S, Moltedo O, Pagliuca G, Lerose R, Turco MC. 2007. Apoptosis inhibition in cancer cells: A novel molecular pathway that involves BAG3 protein. Int J Biochem Cell Biol 39: 1337-1342.
-
(2007)
Int J Biochem Cell Biol
, vol.39
, pp. 1337-1342
-
-
Rosati, A.1
Ammirante, M.2
Gentilella, A.3
Basile, A.4
Festa, M.5
Pascale, M.6
Marzullo, L.7
Belisario, M.A.8
Tosco, A.9
Franceschelli, S.10
Moltedo, O.11
Pagliuca, G.12
Lerose, R.13
Turco, M.C.14
-
35
-
-
79960008971
-
BAG3: A multifaceted protein that regulates major cell pathways
-
Rosati A, Graziano V, De Laurenzi V, Pascale M, Turco MC. 2011. BAG3: A multifaceted protein that regulates major cell pathways. Cell Death Dis 2: e141.
-
(2011)
Cell Death Dis
, vol.2
-
-
Rosati, A.1
Graziano, V.2
De Laurenzi, V.3
Pascale, M.4
Turco, M.C.5
-
36
-
-
0034099743
-
Sodium 4-phenylbutyrate downregulates Hsc70: Implications for intracellular trafficking of ΔF508-CFTR
-
Rubenstein RC, Zeitlin PL. 2000. Sodium 4-phenylbutyrate downregulates Hsc70: Implications for intracellular trafficking of ΔF508-CFTR. Am J Physiol Cell Physiol 278: C259-C267.
-
(2000)
Am J Physiol Cell Physiol
, vol.278
-
-
Rubenstein, R.C.1
Zeitlin, P.L.2
-
37
-
-
79951829938
-
Identification of a NBD1-binding pharmacological chaperone that corrects the trafficking defect of F508del-CFTR
-
Sampson HM, Robert R, Liao J, Matthes E, Carlile GW, Hanrahan JW, Thomas DY. 2011. Identification of a NBD1-binding pharmacological chaperone that corrects the trafficking defect of F508del-CFTR. Chem Biol 18: 231-242.
-
(2011)
Chem Biol
, vol.18
, pp. 231-242
-
-
Sampson, H.M.1
Robert, R.2
Liao, J.3
Matthes, E.4
Carlile, G.W.5
Hanrahan, J.W.6
Thomas, D.Y.7
-
38
-
-
70449701828
-
Deletion of Phe508 in the first nucleotide-binding domain of the cystic fibrosis transmembrane conductance regulator increases its affinity for the heat shock cognate 70 chaperone
-
Scott-Ward TS, Amaral MD. 2009. Deletion of Phe508 in the first nucleotide-binding domain of the cystic fibrosis transmembrane conductance regulator increases its affinity for the heat shock cognate 70 chaperone. FEBS J 276: 7097-7109.
-
(2009)
FEBS J
, vol.276
, pp. 7097-7109
-
-
Scott-Ward, T.S.1
Amaral, M.D.2
-
39
-
-
79953846731
-
Treatment options for cystic fibrosis: State of the art and future perspectives
-
Sears EH, Gartman EJ, Casserly BP. 2011. Treatment options for cystic fibrosis: State of the art and future perspectives. Rev Recent Clin Trials 6: 94-107.
-
(2011)
Rev Recent Clin Trials
, vol.6
, pp. 94-107
-
-
Sears, E.H.1
Gartman, E.J.2
Casserly, B.P.3
-
40
-
-
79955644127
-
Cystic fibrosis and survival to 40 years: A study of CFTR function
-
Simmonds NJ, D'Souza L, Roughton M, Alton EW, Davies JC, Hodson ME. 2011. Cystic fibrosis and survival to 40 years: A study of CFTR function. Eur Respir 37: 1076-1082.
-
(2011)
Eur Respir
, vol.37
, pp. 1076-1082
-
-
Simmonds, N.J.1
D'Souza, L.2
Roughton, M.3
Alton, E.W.4
Davies, J.C.5
Hodson, M.E.6
-
41
-
-
46749108883
-
Chemical rescue of deltaF508-CFTR mimics genetic repair in cystic fibrosis bronchial epithelial cells
-
Singh OV, Pollard HB, Zeitlin PL. 2008. Chemical rescue of deltaF508-CFTR mimics genetic repair in cystic fibrosis bronchial epithelial cells. Mol Cell Proteomics 7: 1099-1110.
-
(2008)
Mol Cell Proteomics
, vol.7
, pp. 1099-1110
-
-
Singh, O.V.1
Pollard, H.B.2
Zeitlin, P.L.3
-
42
-
-
77955257617
-
CHIP participates in protein triage decisions by preferentially ubiquitinating Hsp70-bound substrates
-
Stankiewicz M, Nikolay R, Rybin V, Mayer MP. 2010. CHIP participates in protein triage decisions by preferentially ubiquitinating Hsp70-bound substrates. FEBS J 277: 3353-3367.
-
(2010)
FEBS J
, vol.277
, pp. 3353-3367
-
-
Stankiewicz, M.1
Nikolay, R.2
Rybin, V.3
Mayer, M.P.4
-
43
-
-
33744831154
-
Rescue of DeltaF508-CFTR trafficking and gating in human cystic fibrosis airway primary cultures by small molecules
-
Van Goor F, Straley KS, Cao D, Gonzalez J, Hadida S, Hazlewood A, Joubran J, Knapp T, Makings LR, Miller M, Neuberger T, Olson E, Panchenko V, Rader J, Singh A, Stack JH, Tung R, Grootenhuis PD, Negulescu P. 2006. Rescue of DeltaF508-CFTR trafficking and gating in human cystic fibrosis airway primary cultures by small molecules. Am J Physiol Lung Cell Mol Physiol 290: L1117-L1130.
-
(2006)
Am J Physiol Lung Cell Mol Physiol
, vol.290
-
-
Van Goor, F.1
Straley, K.S.2
Cao, D.3
Gonzalez, J.4
Hadida, S.5
Hazlewood, A.6
Joubran, J.7
Knapp, T.8
Makings, L.R.9
Miller, M.10
Neuberger, T.11
Olson, E.12
Panchenko, V.13
Rader, J.14
Singh, A.15
Stack, J.H.16
Tung, R.17
Grootenhuis, P.D.18
Negulescu, P.19
-
44
-
-
0141924104
-
Movement disorders possibly induced by traditional Chinese herbs
-
Wang XP, Yang RM. 2003. Movement disorders possibly induced by traditional Chinese herbs. Eur Neurol 50: 153-159.
-
(2003)
Eur Neurol
, vol.50
, pp. 153-159
-
-
Wang, X.P.1
Yang, R.M.2
-
45
-
-
0035324274
-
Studies on metabolism of Oxymatrine by human intestinal bacteria
-
Wang ML, Zhou QL, Wang BX. 2001. Studies on metabolism of Oxymatrine by human intestinal bacteria. Zhongguo Zhong Yao Za Zhi 26: 272-274.
-
(2001)
Zhongguo Zhong Yao Za Zhi
, vol.26
, pp. 272-274
-
-
Wang, M.L.1
Zhou, Q.L.2
Wang, B.X.3
-
46
-
-
33750842131
-
Hsp90 cochaperone Aha1 downregulation rescues misfolding of CFTR in cystic fibrosis
-
Wang X, Venable J, LaPointe P, Hutt DM, Koulov AV, Coppinger J, Gurkan C, Kellner W, Matteson J, Plutner H, Riordan JR, Kelly JW, Yates JR III, Balch WE. 2006. Hsp90 cochaperone Aha1 downregulation rescues misfolding of CFTR in cystic fibrosis. Cell 127: 803-815.
-
(2006)
Cell
, vol.127
, pp. 803-815
-
-
Wang, X.1
Venable, J.2
LaPointe, P.3
Hutt, D.M.4
Koulov, A.V.5
Coppinger, J.6
Gurkan, C.7
Kellner, W.8
Matteson, J.9
Plutner, H.10
Riordan, J.R.11
Kelly, J.W.12
Yates III, J.R.13
Balch, W.E.14
-
47
-
-
36348989763
-
Correctors promote maturation of cystic fibrosis transmembrane conductance regulator (CFTR)-processing mutants by binding to the protein
-
Wang Y, Loo TW, Bartlett MC, Clarke DM. 2007. Correctors promote maturation of cystic fibrosis transmembrane conductance regulator (CFTR)-processing mutants by binding to the protein. J Biol Chem 16: 33247-33251.
-
(2007)
J Biol Chem
, vol.16
, pp. 33247-33251
-
-
Wang, Y.1
Loo, T.W.2
Bartlett, M.C.3
Clarke, D.M.4
-
48
-
-
77951211566
-
Heat stress cognate 70 host protein as a potential drug target against drug resistence in hepatitis B virus
-
Wang YP, Liu F, He HW, Han YX, Peng ZG, Li BW, You XF, Song DQ, Li ZR, Yu LY, Cen S, Hong B, Sun CH, Zhao LX, Kreiswirth B, Perlin D, Shao RG, Jiang JD. 2010a. Heat stress cognate 70 host protein as a potential drug target against drug resistence in hepatitis B virus. Antimicrob Agents Chemother 54: 2070-2077.
-
(2010)
Antimicrob Agents Chemother
, vol.54
, pp. 2070-2077
-
-
Wang, Y.P.1
Liu, F.2
He, H.W.3
Han, Y.X.4
Peng, Z.G.5
Li, B.W.6
You, X.F.7
Song, D.Q.8
Li, Z.R.9
Yu, L.Y.10
Cen, S.11
Hong, B.12
Sun, C.H.13
Zhao, L.X.14
Kreiswirth, B.15
Perlin, D.16
Shao, R.G.17
Jiang, J.D.18
-
50
-
-
14544308312
-
The involvement of central cholinergic system in (+)-matrine-induced antinociception in mice
-
Yin LL, Zhu XZ. 2005. The involvement of central cholinergic system in (+)-matrine-induced antinociception in mice. Pharmacol Biochem Behav 80: 419-425.
-
(2005)
Pharmacol Biochem Behav
, vol.80
, pp. 419-425
-
-
Yin, L.L.1
Zhu, X.Z.2
-
51
-
-
41849133213
-
4′-Methyl-4,5′-bithiazole-based correctors of defective ΔF508-CFTR cellular processing
-
Yoo CL, Yu GJ, Yang B, Robins LI, Verkman AS, Kurth MJ. 2008. 4′-Methyl-4, 5′-bithiazole-based correctors of defective ΔF508-CFTR cellular processing. Bioorg Med Chem Lett 18: 2610-2614.
-
(2008)
Bioorg Med Chem Lett
, vol.18
, pp. 2610-2614
-
-
Yoo, C.L.1
Yu, G.J.2
Yang, B.3
Robins, L.I.4
Verkman, A.S.5
Kurth, M.J.6
-
52
-
-
11244349206
-
A foldable CFTR-ΔF508 biogenic intermediate accumulates upon inhibition of the Hsc70-CHIP E3 ubiquitin ligase
-
Younger JM, Ren HY, Chen L, Fields A, Patterson C, Cyr DM. 2004. A foldable CFTR-ΔF508 biogenic intermediate accumulates upon inhibition of the Hsc70-CHIP E3 ubiquitin ligase. J Cell Biol 167: 1075-1085.
-
(2004)
J Cell Biol
, vol.167
, pp. 1075-1085
-
-
Younger, J.M.1
Ren, H.Y.2
Chen, L.3
Fields, A.4
Patterson, C.5
Cyr, D.M.6
-
53
-
-
78649545898
-
Effects of Matrine and Oxymatrine on catalytic activity of cytochrome P450s in rats
-
Yuan F, Chen J, Wu WJ, Chen SZ, Wang XD, Su Z, Huang M. 2010. Effects of Matrine and Oxymatrine on catalytic activity of cytochrome P450s in rats. Basic Clin Pharmacol Toxicol 107: 906-913.
-
(2010)
Basic Clin Pharmacol Toxicol
, vol.107
, pp. 906-913
-
-
Yuan, F.1
Chen, J.2
Wu, W.J.3
Chen, S.Z.4
Wang, X.D.5
Su, Z.6
Huang, M.7
-
54
-
-
55249100081
-
Sophocarpine and matrine inhibit the production of TNF-〈 and IL-6 in murine macrophages and prevent cachexia-related symptoms induced by colon26 adenocarcinoma in mice
-
Zhang Y, Wang S, Li Y, Xiao Z, Hu Z, Zhang J. 2008. Sophocarpine and matrine inhibit the production of TNF-〈 and IL-6 in murine macrophages and prevent cachexia-related symptoms induced by colon26 adenocarcinoma in mice. Int Immunopharmacol 8: 1767-1772.
-
(2008)
Int Immunopharmacol
, vol.8
, pp. 1767-1772
-
-
Zhang, Y.1
Wang, S.2
Li, Y.3
Xiao, Z.4
Hu, Z.5
Zhang, J.6
-
55
-
-
59049108067
-
Determination of oxymatrine and its metabolite matrine in rat blood and dermal microdialysates by high throughput liquid chromatography/tandem mass spectrometry
-
Zheng H, Chen G, Shi L, Lou Z, Chen F, Hu J. 2009. Determination of oxymatrine and its metabolite matrine in rat blood and dermal microdialysates by high throughput liquid chromatography/tandem mass spectrometry. J Pharm Biomed Anal 49: 427-433.
-
(2009)
J Pharm Biomed Anal
, vol.49
, pp. 427-433
-
-
Zheng, H.1
Chen, G.2
Shi, L.3
Lou, Z.4
Chen, F.5
Hu, J.6
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