Sophocarpine and matrine inhibit the production of TNF-α and IL-6 in murine macrophages and prevent cachexia-related symptoms induced by colon26 adenocarcinoma in mice

International Immunopharmacology

Volumn 8, Issue 13-14, 2008, Pages 1767-1772

  Zhang, Yuefan ^a   Wang, Shaozhan ^a   Li, Yuanyuan ^a   Xiao, Zhenyu ^a   Hu, Zhenlin ^a   Zhang, Junping ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Cachexia; Matrine; Pro inflammatory cytokine; Sophocarpine

Indexed keywords

ALKALOID DERIVATIVE; INTERLEUKIN 6; MATRINE; MESSENGER RNA; OXYMATRINE; SOPHOCARPINE; SOPHORAMINE; SOPHORIDINE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD LEVEL; CACHEXIA; CANCER INHIBITION; COLON ADENOCARCINOMA; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG EFFICACY; DRUG MECHANISM; DRUG POTENCY; EPIDIDYMIS; FEMALE; FOOD INTAKE; GASTROCNEMIUS MUSCLE; MACROPHAGE; MALE; MOUSE; MUSCLE ATROPHY; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WEIGHT REDUCTION;

ADENOCARCINOMA; ALKALOIDS; ANIMALS; CACHEXIA; CELL LINE; COLONIC NEOPLASMS; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; MACROPHAGES; MALE; MICE; MICE, INBRED BALB C; QUINOLIZINES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 55249100081     PISSN: 15675769     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.intimp.2008.08.008     Document Type: Article

References (40)

1. Gordon J.N., Green S.R., and Goggin P.M. Cancer cachexia. Qjm 98 11 (2005) 779-788
2. Tisdale M.J. Cachexia in cancer patients. Nat Rev Cancer 2 11 (2002) 862-871
3. Muscaritoli M., Bossola M., Aversa Z., Bellantone R., and Rossi Fanelli F. Prevention and treatment of cancer cachexia: new insights into an old problem. Eur J Cancer 42 1 (2006) 31-41
4. Lelbach A., Muzes G., and Feher J. Current perspectives of catabolic mediators of cancer cachexia. Med Sci Monit 13 9 (2007) RA168-RA173
5. Yamamoto N., Kawamura I., Nishigaki F., Tsujimoto S., Naoe Y., Inami M., et al. Effect of FR143430, a novel cytokine suppressive agent, on adenocarcinoma colon26-induced cachexia in mice. Anticancer Res 18 1A (1998) 139-144
6. Tanaka K., Urata N., Mikami M., Ogasawara M., Matsunaga T., Terashima N., et al. Effect of iguratimod and other anti-rheumatic drugs on adenocarcinoma colon 26-induced cachexia in mice. Inflamm Res 56 1 (2007) 17-23
7. Strassmann G., Fong M., Kenney J.S., and Jacob C.O. Evidence for the involvement of interleukin 6 in experimental cancer cachexia. J Clin Invest 89 5 (1992) 1681-1684
8. Strassmann G., and Kambayashi T. Inhibition of experimental cancer cachexia by anti-cytokine and anti-cytokine-receptor therapy. Cytokines Mol Ther 1 2 (1995) 107-113
9. Kawamura I., Morishita R., Tomita N., Lacey E., Aketa M., Tsujimoto S., et al. Intratumoral injection of oligonucleotides to the NF kappa B binding site inhibits cachexia in a mouse tumor model. Gene Ther 6 1 (1999) 91-97
10. Kuroda K., Horiguchi Y., Nakashima J., Kikuchi E., Kanao K., Miyajima A., et al. Prevention of cancer cachexia by a novel nuclear factor {kappa}B inhibitor in prostate cancer. Clin Cancer Res 11 15 (2005) 5590-5594
11. Nai Y.J., Jiang Z.W., Wang Z.M., Li N., and Li J.S. Prevention of cancer cachexia by pyrrolidine dithiocarbamate (PDTC) in colon 26 tumor-bearing mice. JPEN J Parenter Enteral Nutr 31 1 (2007) 18-25
12. Cerchietti L.C., Navigante A.H., and Castro M.A. Effects of eicosapentaenoic and docosahexaenoic n-3 fatty acids from fish oil and preferential Cox-2 inhibition on systemic syndromes in patients with advanced lung cancer. Nutr Cancer 59 1 (2007) 14-20
13. Liu M., Liu X.Y., and Cheng J.F. [Advance in the pharmacological research on matrine]. Zhongguo Zhong Yao Za Zhi 28 9 (2003) 801-804
14. Ma L., Wen S., Zhan Y., He Y., Liu X., and Jiang J. Anticancer effects of the Chinese medicine matrine on murine hepatocellular carcinoma cells. Planta Med 74 3 (2008) 245-251
15. Liu S.X., and Chiou G.C. Effects of Chinese herbal products on mammalian retinal functions. J Ocul Pharmacol Ther 12 3 (1996) 377-386
16. Jiang H., Hou C., Zhang S., Xie H., Zhou W., Jin Q., et al. Matrine upregulates the cell cycle protein E2F-1 and triggers apoptosis via the mitochondrial pathway in K562 cells. Eur J Pharmacol 559 2-3 (2007) 98-108
17. Azzam H.S., Goertz C., Fritts M., and Jonas W.B. Natural products and chronic hepatitis C virus. Liver Int 27 1 (2007) 17-25
18. Yamazaki M. [The pharmacological studies on matrine and oxymatrine]. Yakugaku Zasshi 120 10 (2000) 1025-1033
19. Zhang M.J., and Huang J. [Recent research progress of anti-tumor mechanism matrine]. Zhongguo Zhong Yao Za Zhi 29 2 (2004) 115-118
20. Hu Z.L., Zhang J.P., Yu X.B., Lin W., Qian D.H., and Wan M.B. Effect of matrine on lipopolysaccharides/d-galactosamine-induced hepatitis and tumor necrosis factor release from macrophages in vitro. Zhongguo Yao Li Xue Bao 17 4 (1996) 351-353
21. Hu Z.L., Zhang J.P., Wan M.B., Yu X.B., Lin W., and Qian D.H. [Effect of matrine on mouse hepatitis and tumor necrosis factor production induced by Propionibacterium acnes/lipopolysaccharides]. Yao Xue Xue Bao 31 9 (1996) 662-665
22. Hu Z.L., Zhang J.P., Qian D.H., Lin W., Xie W.F., Zhang X.R., et al. Effects of matrine on mouse splenocyte proliferation and release of interleukin-1 and -6 from peritoneal macrophages in vitro. Zhongguo Yao Li Xue Bao 17 3 (1996) 259-261
23. Lin W., Zhang J.P., Hu Z.L., and Qian D.H. [Inhibitory effect of matrine on lipopolysacchride-induced tumor necrosis factor and interleukin-6 production from rat Kupffer cells]. Yao Xue Xue Bao 32 2 (1997) 93-96
24. Zheng P., Niu F.L., Liu W.Z., Shi Y., and Lu L.G. Anti-inflammatory mechanism of oxymatrine in dextran sulfate sodium-induced colitis of rats. World J Gastroenterol 11 31 (2005) 4912-4915
25. Xu G.L., Yao L., Rao S.Y., Gong Z.N., Zhang S.Q., and Yu S.Q. Attenuation of acute lung injury in mice by oxymatrine is associated with inhibition of phosphorylated p38 mitogen-activated protein kinase. J Ethnopharmacol 98 1-2 (2005) 177-183
26. Zhu X.H., Qiu Y.D., Shen H., Shi M.K., and Ding Y.T. Effect of matrine on Kupffer cell activation in cold ischemia reperfusion injury of rat liver. World J Gastroenterol 8 6 (2002) 1112-1116
27. Liu J.Y., Hu J.H., Zhu Q.G., Li F.Q., Wang J., and Sun H.J. Effect of matrine on the expression of substance P receptor and inflammatory cytokines production in human skin keratinocytes and fibroblasts. Int Immunopharmacol 7 6 (2007) 816-823
28. Livak K.J., and Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 25 4 (2001) 402-408
29. Argiles J.M., Busquets S., and Lopez-Soriano F.J. Cytokines in the pathogenesis of cancer cachexia. Curr Opin Clin Nutr Metab Care 6 4 (2003) 401-406
30. Langstein H.N., Doherty G.M., Fraker D.L., Buresh C.M., and Norton J.A. The roles of gamma-interferon and tumor necrosis factor alpha in an experimental rat model of cancer cachexia. Cancer Res 51 9 (1991) 2302-2306
31. Costelli P., Carbo N., Tessitore L., Bagby G.J., Lopez-Soriano F.J., Argiles J.M., et al. Tumor necrosis factor-alpha mediates changes in tissue protein turnover in a rat cancer cachexia model. J Clin Invest 92 6 (1993) 2783-2789
32. Oliff A., Defeo-Jones D., Boyer M., Martinez D., Kiefer D., Vuocolo G., et al. Tumors secreting human TNF/cachectin induce cachexia in mice. Cell 50 4 (1987) 555-563
33. Tanaka Y., Eda H., Tanaka T., Udagawa T., Ishikawa T., Horii I., et al. Experimental cancer cachexia induced by transplantable colon 26 adenocarcinoma in mice. Cancer Res 50 8 (1990) 2290-2295
34. Soda K., Kawakami M., Kashii A., and Miyata M. Characterization of mice bearing subclones of colon 26 adenocarcinoma disqualifies interleukin-6 as the sole inducer of cachexia. Jpn J Cancer Res 85 11 (1994) 1124-1130
35. Strassmann G., Jacob C.O., Evans R., Beall D., and Fong M. Mechanisms of experimental cancer cachexia. Interaction between mononuclear phagocytes and colon-26 carcinoma and its relevance to IL-6-mediated cancer cachexia. J Immunol 148 11 (1992) 3674-3678
36. Strassmann G., Masui Y., Chizzonite R., and Fong M. Mechanisms of experimental cancer cachexia. Local involvement of IL-1 in colon-26 tumor. J Immunol 150 6 (1993) 2341-2345
37. Yasumoto K., Mukaida N., Harada A., Kuno K., Akiyama M., Nakashima E., et al. Molecular analysis of the cytokine network involved in cachexia in colon 26 adenocarcinoma-bearing mice. Cancer Res 55 4 (1995) 921-927
38. Fujiki F., Mukaida N., Hirose K., Ishida H., Harada A., Ohno S., et al. Prevention of adenocarcinoma colon 26-induced cachexia by interleukin 10 gene transfer. Cancer Res 57 1 (1997) 94-99
39. Zhou W., Jiang Z.W., Tian J., Jiang J., Li N., and Li J.S. Role of NF-kappaB and cytokine in experimental cancer cachexia. World J Gastroenterol 9 7 (2003) 1567-1570
40. Strassmann G., Fong M., Freter C.E., Windsor S., D'Alessandro F., and Nordan R.P. Suramin interferes with interleukin-6 receptor binding in vitro and inhibits colon-26-mediated experimental cancer cachexia in vivo. J Clin Invest 92 5 (1993) 2152-2159