Synthesis and in vitro inhibitory activity of matrine derivatives towards pro-inflammatory cytokines

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 24, 2010, Pages 7537-7539

  Hu, Honggang ^a   Wang, Shaozhan ^a   Zhang, Chunmei ^a   Wang, Liang ^b   Ding, Li ^a   Zhang, Junping ^a   Wu, Qiuye ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b YANTAI UNIVERSITY   (China)

Author keywords

Derivatives; Matrine; NF B; Pro inflammatory cytokine; SAR

Indexed keywords

LIPOPOLYSACCHARIDE; MATRINE; SOPHORA FLAVESCENS EXTRACT; SOPHORAMINE; TUMOR NECROSIS FACTOR ALPHA;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG STRUCTURE; DRUG SYNTHESIS; GENETIC TRANSCRIPTION; IN VITRO STUDY; INFLAMMATION; MICHAEL ADDITION;

ALKALOIDS; ANIMALS; CELL LINE, TUMOR; MICE; NF-KAPPA B; QUINOLIZINES; SOPHORA; TUMOR NECROSIS FACTOR-ALPHA;

SOPHORA;

EID: 78449313543     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.09.075     Document Type: Article

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