메뉴 건너뛰기




Volumn 9, Issue 6, 2012, Pages 687-700

Amphiphilic polymeric micelles as the nanocarrier for peroral delivery of poorly soluble anticancer drugs

Author keywords

Anticancer drug; Nanocarriers; Oral delivery; Polymeric micelles; Poorly soluble

Indexed keywords

'TAXOL'; ANTINEOPLASTIC AGENT; BUTYRIC ACID; CAMPTOTHECIN; CHITOSAN; CYCLOSPORIN; DOCETAXEL; DOXORUBICIN; ETOPOSIDE; FLUOROURACIL; HYALURONIC ACID; ITRACONAZOLE; KETOCONAZOLE; MACROGOL; MITOMYCIN C; NANOCARRIER; PACLITAXEL; POLOXAMER; UNCLASSIFIED DRUG;

EID: 84862069884     PISSN: 17425247     EISSN: 17447593     Source Type: Journal    
DOI: 10.1517/17425247.2012.681299     Document Type: Review
Times cited : (79)

References (103)
  • 1
    • 78650277214 scopus 로고    scopus 로고
    • Delivery of nanoparticulate drug delivery systems via the intravenous route for cancer gene therapy
    • Hallaj-Nezhadi S, Lotfipour F, Dass CR. Delivery of nanoparticulate drug delivery systems via the intravenous route for cancer gene therapy. Pharmazie 2010;65(12):855-9
    • (2010) Pharmazie , vol.65 , Issue.12 , pp. 855-859
    • Hallaj-Nezhadi, S.1    Lotfipour, F.2    Dass, C.R.3
  • 2
    • 43449084030 scopus 로고    scopus 로고
    • Polymeric micelles in oral chemotherapy
    • Bromberg L. Polymeric micelles in oral chemotherapy. J Control Release 2008;128(2):99-112
    • (2008) J Control Release , vol.128 , Issue.2 , pp. 99-112
    • Bromberg, L.1
  • 3
    • 83355173904 scopus 로고    scopus 로고
    • Goblet cell-targeting nanoparticles for oral insulin delivery and the influence of mucus on insulin transport
    • Jin Y, Song Y, Zhu X, et al. Goblet cell-targeting nanoparticles for oral insulin delivery and the influence of mucus on insulin transport. Biomaterials 2012;33(5):1573-82
    • (2012) Biomaterials , vol.33 , Issue.5 , pp. 1573-1582
    • Jin, Y.1    Song, Y.2    Zhu, X.3
  • 4
    • 79951769859 scopus 로고    scopus 로고
    • The antitumor efficacy of functional paclitaxel nanomicelles in treating resistant breast cancers by oral delivery
    • Yao HJ, Ju RJ, Wang XX, et al. The antitumor efficacy of functional paclitaxel nanomicelles in treating resistant breast cancers by oral delivery. Biomaterials 2011;32(12):3285-302
    • (2011) Biomaterials , vol.32 , Issue.12 , pp. 3285-3302
    • Yao, H.J.1    Ju, R.J.2    Wang, X.X.3
  • 5
    • 46649085083 scopus 로고    scopus 로고
    • Pharmacokinetics and targeting property of TFu-loaded liposomes with different sizes after intravenous and oral administration
    • DOI 10.1080/10611860801927598, PII 793648803
    • Sun W, Zou W, Huang G, et al. Pharmacokinetics and targeting property of TFu-loaded liposomes with different sizes after intravenous and oral administration. J Drug Target 2008;16(5):357-65 (Pubitemid 351935733)
    • (2008) Journal of Drug Targeting , vol.16 , Issue.5 , pp. 357-365
    • Sun, W.1    Zou, W.2    Huang, G.3    Li, A.4    Zhang, N.5
  • 7
    • 80855139562 scopus 로고    scopus 로고
    • Spray-dried oil-in-water emulsion to improve the intestinal absorption and oral bioavailability of ZLR-8, a nitric oxide-releasing derivative of diclofenac
    • Zhang J, Zheng Z, Gao Y, et al. Spray-dried oil-in-water emulsion to improve the intestinal absorption and oral bioavailability of ZLR-8, a nitric oxide-releasing derivative of diclofenac. J Pharm Pharmacol 2011;63(12):1531-8
    • (2011) J Pharm Pharmacol , vol.63 , Issue.12 , pp. 1531-1538
    • Zhang, J.1    Zheng, Z.2    Gao, Y.3
  • 8
    • 84862062066 scopus 로고    scopus 로고
    • Enhanced dissolution rate and oral bioavailability of simvastatin nanocrystal prepared by sonoprecipitation
    • in press
    • Jiang T, Han N, Zhao B, et al. Enhanced dissolution rate and oral bioavailability of simvastatin nanocrystal prepared by sonoprecipitation. Drug Dev Ind Pharm 2012 (in press)
    • (2012) Drug Dev Ind Pharm
    • Jiang, T.1    Han, N.2    Zhao, B.3
  • 9
    • 79551627638 scopus 로고    scopus 로고
    • Experimental study of cisplatin loaded polylactic acid-polyethylene glycol nano-particles for targeting oral carcinoma
    • Yang K, Chen SW, Chen R, et al. Experimental study of cisplatin loaded polylactic acid-polyethylene glycol nano-particles for targeting oral carcinoma. Hua Xi Kou Qiang Yi Xue Za Zhi 2005;23(5):445-8
    • (2005) Hua Xi Kou Qiang Yi Xue Za Zhi , vol.23 , Issue.5 , pp. 445-448
    • Yang, K.1    Chen, S.W.2    Chen, R.3
  • 11
    • 77949526367 scopus 로고    scopus 로고
    • Phase i pharmacokinetic study of aweekly liposomal paclitaxel formulation (Genexol-PM) in patients with solid tumors
    • Lim WT, Tan EH, Toh CK, et al. Phase I pharmacokinetic study of aweekly liposomal paclitaxel formulation (Genexol-PM) in patients with solid tumors. Ann Oncol 2010;21(2):382-8
    • (2010) Ann Oncol , vol.21 , Issue.2 , pp. 382-388
    • Lim, W.T.1    Tan, E.H.2    Toh, C.K.3
  • 12
    • 79955522520 scopus 로고    scopus 로고
    • The mechanism of enhancement on oral absorption of paclitaxel by N-octyl-Osulfate chitosan micelles
    • Mo R, Jin X, Li N, et al. The mechanism of enhancement on oral absorption of paclitaxel by N-octyl-Osulfate chitosan micelles. Biomaterials 2011;32(20):4609-20
    • (2011) Biomaterials , vol.32 , Issue.20 , pp. 4609-4620
    • Mo, R.1    Jin, X.2    Li, N.3
  • 13
    • 33749663431 scopus 로고    scopus 로고
    • Self-assembled nanoparticles of poly(lactide)-Vitamin E TPGS copolymers for oral chemotherapy
    • DOI 10.1016/j.ijpharm.2006.06.013, PII S0378517306004558
    • Zhang Z, Feng SS. Self-assembled nanoparticles of poly(lactide) - vitamin ETPGS copolymers for oral chemotherapy. Int J Pharm 2006;324(2):191-8 (Pubitemid 44550164)
    • (2006) International Journal of Pharmaceutics , vol.324 , Issue.2 , pp. 191-198
    • Zhang, Z.1    Feng, S.-S.2
  • 14
    • 33744908869 scopus 로고    scopus 로고
    • Drug evaluation: ADI-PEG-20 - A PEGylated arginine deiminase for arginine-auxotrophic cancers
    • Shen LJ, Shen WC. Drug evaluation: ADI-PEG-20 - a PEGylated arginine deiminase for arginine-auxotrophic cancers. Curr Opin Mol Ther 2006;8(3):240-8
    • (2006) Curr Opin Mol Ther , vol.8 , Issue.3 , pp. 240-248
    • Shen, L.J.1    Shen, W.C.2
  • 15
    • 0032012967 scopus 로고    scopus 로고
    • PEG-liposome in DDS and clinical studies
    • Maruyama K. PEG-liposome in DDS and clinical studies. Nippon Rinsho 1998;56(3):632-7
    • (1998) Nippon Rinsho , vol.56 , Issue.3 , pp. 632-637
    • Maruyama, K.1
  • 16
    • 33846861762 scopus 로고    scopus 로고
    • Investigation of pluronic and PEG-PE micelles as carriers of meso-tetraphenyl porphine for oral administration
    • DOI 10.1016/j.ijpharm.2006.09.030, PII S0378517306007824
    • Sezgin Z, Yuksel N, Baykara T. Investigation of pluronic and PEG-PE micelles as carriers of meso-tetraphenyl porphine for oral administration. Int J Pharm 2007;332(1-2):161-7 (Pubitemid 46227770)
    • (2007) International Journal of Pharmaceutics , vol.332 , Issue.1-2 , pp. 161-167
    • Sezgin, Z.1    Yuksel, N.2    Baykara, T.3
  • 17
    • 67650140668 scopus 로고    scopus 로고
    • Transepithelial transport of PEGylated anionic poly(amidoamine) dendrimers: Implications for oral drug delivery
    • Sweet DM, Kolhatkar RB, Ray A, et al. Transepithelial transport of PEGylated anionic poly(amidoamine) dendrimers: implications for oral drug delivery. J Control Release 2009;138(1):78-85
    • (2009) J Control Release , vol.138 , Issue.1 , pp. 78-85
    • Sweet, D.M.1    Kolhatkar, R.B.2    Ray, A.3
  • 20
    • 31144453388 scopus 로고    scopus 로고
    • Encapsulation of amphotericin B in poly(ethylene glycol)-block- poly(ε- caprolactone-co-trimethylenecarbonate) polymeric micelles
    • DOI 10.1016/j.ijpharm.2005.11.031, PII S0378517305008057
    • Vandermeulen G, Rouxhet L, Arien A, et al. Encapsulation of amphotericin B in poly(ethylene glycol)-block-poly(epsiloncaprolactone-co- trimethylenecarbonate) polymeric micelles. Int J Pharm 2006;309(1-2):234-40 (Pubitemid 43129487)
    • (2006) International Journal of Pharmaceutics , vol.309 , Issue.1-2 , pp. 234-240
    • Vandermeulen, G.1    Rouxhet, L.2    Arien, A.3    Brewster, M.E.4    Preat, V.5
  • 21
    • 70349327622 scopus 로고    scopus 로고
    • Novel self-assembling PEG-p-(CLco-TMC) polymeric micelles as safe and effective delivery system for paclitaxel
    • Danhier F, Magotteaux N, Ucakar B, et al. Novel self-assembling PEG-p-(CLco-TMC) polymeric micelles as safe and effective delivery system for paclitaxel. Eur J Pharm Biopharm 2009;73(2):230-8
    • (2009) Eur J Pharm Biopharm , vol.73 , Issue.2 , pp. 230-238
    • Danhier, F.1    Magotteaux, N.2    Ucakar, B.3
  • 22
    • 35648954063 scopus 로고    scopus 로고
    • A simple method for the preparation of PEG-6-mercaptopurine for oral administration
    • DOI 10.1016/j.bmcl.2007.09.064, PII S0960894X07011171
    • Zacchigna M, Cateni F, Di Luca G, et al. A simple method for the preparation of PEG-6-mercaptopurine for oral administration. Bioorg Med Chem Lett 2007;17(23):6607-9 (Pubitemid 350026319)
    • (2007) Bioorganic and Medicinal Chemistry Letters , vol.17 , Issue.23 , pp. 6607-6609
    • Zacchigna, M.1    Cateni, F.2    Di Luca, G.3    Drioli, S.4
  • 23
    • 33846443159 scopus 로고    scopus 로고
    • Hydrotropic polymeric micelles for enhanced paclitaxel solubility: In vitro and in vivo characterization
    • DOI 10.1021/bm060307b
    • Lee SC, Huh KM, Lee J, et al. Hydrotropic polymeric micelles for enhanced paclitaxel solubility: in vitro and in vivo characterization. Biomacromolecules 2007;8(1):202-8 (Pubitemid 46140493)
    • (2007) Biomacromolecules , vol.8 , Issue.1 , pp. 202-208
    • Lee, S.C.1    Huh, K.M.2    Lee, J.3    Cho, Y.W.4    Galinsky, R.E.5    Park, K.6
  • 24
    • 77953020323 scopus 로고    scopus 로고
    • Preparation and evaluation of poly (Ethylene Glycol)-poly(Lactide) micelles as nanocarriers for oral delivery of cyclosporine A
    • Zhang Y, Li X, Zhou Y, et al. Preparation and evaluation of poly (Ethylene Glycol)-poly(Lactide) micelles as nanocarriers for oral delivery of cyclosporine A. Nanoscale Res Lett 2010;5(6):917-25
    • (2010) Nanoscale Res Lett , vol.5 , Issue.6 , pp. 917-925
    • Zhang, Y.1    Li, X.2    Zhou, Y.3
  • 25
    • 75149133614 scopus 로고    scopus 로고
    • Chitosan-based formulations for delivery of DNA and siRNA
    • Mao S, Sun W, Kissel T. Chitosan-based formulations for delivery of DNA and siRNA. Adv Drug Deliv Rev 2010;62(1):12-27
    • (2010) Adv Drug Deliv Rev , vol.62 , Issue.1 , pp. 12-27
    • Mao, S.1    Sun, W.2    Kissel, T.3
  • 26
    • 51449104994 scopus 로고    scopus 로고
    • A novel nanoparticle formulation for sustained paclitaxel delivery
    • Trickler WJ, Nagvekar AA, Dash AK. A novel nanoparticle formulation for sustained paclitaxel delivery. AAPS PharmSciTech 2008;9(2):486-93
    • (2008) AAPS PharmSciTech , vol.9 , Issue.2 , pp. 486-493
    • Trickler, W.J.1    Nagvekar, A.A.2    Dash, A.K.3
  • 27
    • 75149147998 scopus 로고    scopus 로고
    • Targeted delivery of low molecular drugs using chitosan and its derivatives
    • Park JH, Saravanakumar G, Kim K, et al. Targeted delivery of low molecular drugs using chitosan and its derivatives. Adv Drug Deliv Rev 2010;62(1):28-41
    • (2010) Adv Drug Deliv Rev , vol.62 , Issue.1 , pp. 28-41
    • Park, J.H.1    Saravanakumar, G.2    Kim, K.3
  • 28
    • 79955034696 scopus 로고    scopus 로고
    • Enhancing effect of N-octyl-O-sulfate chitosan on etoposide absorption
    • Mo R, Xiao Y, Sun M, et al. Enhancing effect of N-octyl-O-sulfate chitosan on etoposide absorption. Int J Pharm 2011;409(1-2):38-45
    • (2011) Int J Pharm , vol.409 , Issue.1-2 , pp. 38-45
    • Mo, R.1    Xiao, Y.2    Sun, M.3
  • 30
    • 4744355223 scopus 로고    scopus 로고
    • Hyaluronan catabolism: A new metabolic pathway
    • DOI 10.1078/0171-9335-00392
    • Stern R. Hyaluronan catabolism: a new metabolic pathway. Eur J Cell Biol 2004;83(7):317-25 (Pubitemid 39307169)
    • (2004) European Journal of Cell Biology , vol.83 , Issue.7 , pp. 317-325
    • Stern, R.1
  • 31
    • 0025282411 scopus 로고
    • CD44 is the principal cell surface receptor for hyaluronate
    • Aruffo A, Stamenkovic I, Melnick M, et al. CD44 is the principal cell surface receptor for hyaluronate. Cell 1990;61(7):1303-13
    • (1990) Cell , vol.61 , Issue.7 , pp. 1303-1313
    • Aruffo, A.1    Stamenkovic, I.2    Melnick, M.3
  • 32
    • 33746040501 scopus 로고    scopus 로고
    • Hyaluronan fragments: An information-rich system
    • DOI 10.1016/j.ejcb.2006.05.009, PII S0171933506001014
    • Stern R, Asari AA, Sugahara KN. Hyaluronan fragments: an information-rich system. Eur JCell Biol 2006;85(8):699-715 (Pubitemid 44070579)
    • (2006) European Journal of Cell Biology , vol.85 , Issue.8 , pp. 699-715
    • Stern, R.1    Asari, A.A.2    Sugahara, K.N.3
  • 34
    • 77950519662 scopus 로고    scopus 로고
    • Novel fibrillar insulin formulations for oral administration: Formulation and in vivo studies in diabetic mice
    • Dekel Y, Glucksam Y, Margalit R. Novel fibrillar insulin formulations for oral administration: formulation and in vivo studies in diabetic mice. J Control Release 2010;143(1):128-35
    • (2010) J Control Release , vol.143 , Issue.1 , pp. 128-135
    • Dekel, Y.1    Glucksam, Y.2    Margalit, R.3
  • 35
    • 70350335729 scopus 로고    scopus 로고
    • Self-assembled hyaluronic acid nanoparticles for active tumor targeting
    • Choi KY, Chung H, Min KH, et al. Self-assembled hyaluronic acid nanoparticles for active tumor targeting. Biomaterials 2010;31(1):106-14
    • (2010) Biomaterials , vol.31 , Issue.1 , pp. 106-114
    • Choi, K.Y.1    Chung, H.2    Min, K.H.3
  • 36
    • 58149354721 scopus 로고    scopus 로고
    • In vivo real-time bioimaging of hyaluronic acid derivatives using quantum dots
    • Kim J, Kim KS, Jiang G, et al. In vivo real-time bioimaging of hyaluronic acid derivatives using quantum dots. Biopolymers 2008;89(12):1144-53
    • (2008) Biopolymers , vol.89 , Issue.12 , pp. 1144-1153
    • Kim, J.1    Kim, K.S.2    Jiang, G.3
  • 37
    • 45749088187 scopus 로고    scopus 로고
    • Hyaluronic acid-paclitaxel conjugate micelles: Synthesis, characterization, and antitumor activity
    • DOI 10.1021/bc8000485
    • Lee H, Lee K, Park TG. Hyaluronic acid-paclitaxel conjugate micelles: synthesis, characterization, and antitumor activity. Bioconjug Chem 2008;19(6):1319-25 (Pubitemid 351874956)
    • (2008) Bioconjugate Chemistry , vol.19 , Issue.6 , pp. 1319-1325
    • Lee, H.1    Lee, K.2    Tae, G.P.3
  • 38
    • 77949269580 scopus 로고    scopus 로고
    • The use of amino Acid linkers in the conjugation of paclitaxel with hyaluronic acid as drug delivery system: Synthesis, self-assembled property, drug release, and in vitro efficiency
    • Xin D, Wang Y, Xiang J. The use of amino Acid linkers in the conjugation of paclitaxel with hyaluronic acid as drug delivery system: synthesis, self-assembled property, drug release, and in vitro efficiency. Pharm Res 2010;27(2):380-9
    • (2010) Pharm Res , vol.27 , Issue.2 , pp. 380-389
    • Xin, D.1    Wang, Y.2    Xiang, J.3
  • 39
    • 33947544417 scopus 로고    scopus 로고
    • Oral absorption of hyaluronic acid and phospholipids complexes in rats
    • Huang SL, Ling PX, Zhang TM. Oral absorption of hyaluronic acid and phospholipids complexes in rats. World J Gastroenterol 2007;13(6):945-9
    • (2007) World J Gastroenterol , vol.13 , Issue.6 , pp. 945-949
    • Huang, S.L.1    Ling, P.X.2    Zhang, T.M.3
  • 40
    • 70849114663 scopus 로고    scopus 로고
    • Target specific and long-acting delivery of protein, peptide, and nucleotide therapeutics using hyaluronic acid derivatives
    • Oh EJ, Park K, Kim KS, et al. Target specific and long-acting delivery of protein, peptide, and nucleotide therapeutics using hyaluronic acid derivatives. J Control Release 2010;141(1):2-12
    • (2010) J Control Release , vol.141 , Issue.1 , pp. 2-12
    • Oh, E.J.1    Park, K.2    Kim, K.S.3
  • 41
    • 0034966350 scopus 로고    scopus 로고
    • Modulation of red blood cell aggregation and blood viscosity by the covalent attachment of pluronic copolymers
    • Armstrong JK, Meiselman HJ, Wenby RB, et al. Modulation of red blood cell aggregation and blood viscosity by the covalent attachment of Pluronic copolymers. Biorheology 2001;38(2-3):239-47 (Pubitemid 32573707)
    • (2001) Biorheology , vol.38 , Issue.2-3 , pp. 239-247
    • Armstrong, J.K.1    Meiselman, H.J.2    Wenby, R.B.3    Fisher, T.C.4
  • 42
    • 61849104017 scopus 로고    scopus 로고
    • Novel behavior of heat of micellization of pluronics F68 and F88 in aqueous solutions
    • Tsui HW, Hsu YH, Wang JH, et al. Novel behavior of heat of micellization of pluronics F68 and F88 in aqueous solutions. Langmuir 2008;24(24):13858-62
    • (2008) Langmuir , vol.24 , Issue.24 , pp. 13858-13862
    • Tsui, H.W.1    Hsu, Y.H.2    Wang, J.H.3
  • 43
    • 54249111320 scopus 로고    scopus 로고
    • Prevention of MDR development in leukemia cells by micelle-forming polymeric surfactant
    • Sharma AK, Zhang L, Li S, et al. Prevention of MDR development in leukemia cells by micelle-forming polymeric surfactant. J Control Release 2008;131(3):220-7
    • (2008) J Control Release , vol.131 , Issue.3 , pp. 220-227
    • Sharma, A.K.1    Zhang, L.2    Li, S.3
  • 44
    • 0031665981 scopus 로고    scopus 로고
    • Effects of pluronic P85 unimers and micelles on drug permeability in polarized BBMEC and Caco-2 cells
    • DOI 10.1023/A:1011942814300
    • Batrakova EV, Han HY, Miller DW, et al. Effects of pluronic P85 unimers and micelles on drug permeability in polarized BBMEC and Caco-2 cells. Pharm Res 1998;15(10):1525-32 (Pubitemid 28465737)
    • (1998) Pharmaceutical Research , vol.15 , Issue.10 , pp. 1525-1532
    • Batrakova, E.V.1    Han, H.-Y.2    Miller, D.W.3    Kabanov, A.V.4
  • 45
    • 34848855357 scopus 로고    scopus 로고
    • Pharmaceutical evaluation of genistein-loaded pluronic micelles for oral delivery
    • Kwon SH, Kim SY, Ha KW, et al. Pharmaceutical evaluation of genistein-loaded pluronic micelles for oral delivery. Arch Pharm Res 2007;30(9):1138-43
    • (2007) Arch Pharm Res , vol.30 , Issue.9 , pp. 1138-1143
    • Kwon, S.H.1    Kim, S.Y.2    Ha, K.W.3
  • 46
    • 74449089561 scopus 로고    scopus 로고
    • The effects of mixed MPEG-PLA/Pluronic copolymer micelles on the bioavailability and multidrug resistance of docetaxel
    • Mu CF, Balakrishnan P, Cui FD, et al. The effects of mixed MPEG-PLA/Pluronic copolymer micelles on the bioavailability and multidrug resistance of docetaxel. Biomaterials 2010;31(8):2371-9
    • (2010) Biomaterials , vol.31 , Issue.8 , pp. 2371-2379
    • Mu, C.F.1    Balakrishnan, P.2    Cui, F.D.3
  • 47
    • 62849090441 scopus 로고    scopus 로고
    • A novel mixed micelle gel with thermo-sensitive property for the local delivery of docetaxel
    • Yang Y, Wang J, Zhang X, et al. A novel mixed micelle gel with thermo-sensitive property for the local delivery of docetaxel. J Control Release 2009;135(2):175-82
    • (2009) J Control Release , vol.135 , Issue.2 , pp. 175-182
    • Yang, Y.1    Wang, J.2    Zhang, X.3
  • 48
    • 0032714228 scopus 로고    scopus 로고
    • Inhibition of P-glycoprotein by D-α-tocopheryl polyethylene glycol 1000 succinate (TPGS)
    • DOI 10.1023/A:1015000503629
    • Dintaman JM, Silverman JA. Inhibition of P-glycoprotein by D-alpha-tocopheryl polyethylene glycol 1000 succinate (TPGS). Pharm Res 1999;16(10):1550-6 (Pubitemid 29510551)
    • (1999) Pharmaceutical Research , vol.16 , Issue.10 , pp. 1550-1556
    • Dintaman, J.M.1    Silverman, J.A.2
  • 49
    • 20744447950 scopus 로고    scopus 로고
    • Enhanced oral paclitaxel absorption with vitamin E-TPGS: Effect on solubility and permeability in vitro, in situ and in vivo
    • DOI 10.1016/j.ejps.2005.04.003, PII S0928098705001247
    • Varma MV, Panchagnula R. Enhanced oral paclitaxel absorption with vitamin ETPGS: effect on solubility and permeability in vitro, in situ and in vivo. Eur J Pharm Sci 2005;25(4-5):445-53 (Pubitemid 40853872)
    • (2005) European Journal of Pharmaceutical Sciences , vol.25 , Issue.4-5 , pp. 445-453
    • Varma, M.V.S.1    Panchagnula, R.2
  • 50
    • 0344083669 scopus 로고    scopus 로고
    • PLGA/TPGS Nanoparticles for Controlled Release of Paclitaxel: Effects of the Emulsifier and Drug Loading Ratio
    • DOI 10.1023/B:PHAM.0000003387.15428.42
    • Mu L, Feng SS. PLGA/TPGS nanoparticles for controlled release of paclitaxel: effects of the emulsifier and drug loading ratio. Pharm Res 2003;20(11):1864-72 (Pubitemid 37449463)
    • (2003) Pharmaceutical Research , vol.20 , Issue.11 , pp. 1864-1872
    • Mu, L.1    Feng, S.-S.2
  • 51
    • 33846671426 scopus 로고    scopus 로고
    • Nanoparticles of poly(lactide)-tocopheryl polyethylene glycol succinate (PLA-TPGS) copolymers for protein drug delivery
    • DOI 10.1016/j.biomaterials.2007.01.003, PII S014296120700004X
    • Lee SH, Zhang Z, Feng SS. Nanoparticles of poly(lactide)-tocopheryl polyethylene glycol succinate (PLA-TPGS) copolymers for protein drug delivery. Biomaterials 2007;28(11):2041-50 (Pubitemid 46188359)
    • (2007) Biomaterials , vol.28 , Issue.11 , pp. 2041-2050
    • Lee, S.H.1    Zhang, Z.2    Feng, S.-S.3
  • 53
    • 33646367645 scopus 로고    scopus 로고
    • Polyethylene glycol-phosphatidylethanolamine conjugate (PEG-PE)-based mixed micelles: Some properties, loading with paclitaxel, and modulation of P-glycoprotein-mediated efflux
    • DOI 10.1016/j.ijpharm.2006.02.018, PII S037851730600113X
    • Dabholkar RD, Sawant RM, Mongayt DA, et al. Polyethylene glycol-phosphatidylethanolamine conjugate (PEG-PE)-based mixed micelles: some properties, loading with paclitaxel, and modulation of P-glycoprotein-mediated efflux. Int J Pharm 2006;315(1-2):148-57 (Pubitemid 43674120)
    • (2006) International Journal of Pharmaceutics , vol.315 , Issue.1-2 , pp. 148-157
    • Dabholkar, R.D.1    Sawant, R.M.2    Mongayt, D.A.3    Devarajan, P.V.4    Torchilin, V.P.5
  • 54
    • 11844255659 scopus 로고    scopus 로고
    • Physical characterizations of microemulsion systems using tocopheryl polyethylene glycol 1000 succinate (TPGS) as asurfactant for the oral delivery of protein drugs
    • Ke WT, Lin SY, Ho HO, et al. Physical characterizations of microemulsion systems using tocopheryl polyethylene glycol 1000 succinate (TPGS) as asurfactant for the oral delivery of protein drugs. J Control Release 2005;102(2):489-507
    • (2005) J Control Release , vol.102 , Issue.2 , pp. 489-507
    • Ke, W.T.1    Lin, S.Y.2    Ho, H.O.3
  • 55
    • 10044225776 scopus 로고    scopus 로고
    • Effects of particle size and surface coating on cellular uptake of polymeric nanoparticles for oral delivery of anticancer drugs
    • Win KY, Feng SS. Effects of particle size and surface coating on cellular uptake of polymeric nanoparticles for oral delivery of anticancer drugs. Biomaterials 2005;26(15):2713-22
    • (2005) Biomaterials , vol.26 , Issue.15 , pp. 2713-2722
    • Win, K.Y.1    Feng, S.S.2
  • 56
    • 43849099717 scopus 로고    scopus 로고
    • Preparation and characterization of Pluronic/TPGS mixed micelles for solubilization of camptothecin
    • Gao Y, Li LB, Zhai G. Preparation and characterization of Pluronic/TPGS mixed micelles for solubilization of camptothecin. Colloids Surf B Biointerfaces 2008;64(2):194-9
    • (2008) Colloids Surf B Biointerfaces , vol.64 , Issue.2 , pp. 194-199
    • Gao, Y.1    Li, L.B.2    Zhai, G.3
  • 57
    • 43049139103 scopus 로고    scopus 로고
    • Synthesis of water soluble PEGylated magnetic complexes using mPEG-fatty acid for biomedical applications
    • Lim EK, Yang J, Park MY, et al. Synthesis of water soluble PEGylated magnetic complexes using mPEG-fatty acid for biomedical applications. Colloids Surf B Biointerfaces 2008;64(1):111-17
    • (2008) Colloids Surf B Biointerfaces , vol.64 , Issue.1 , pp. 111-117
    • Lim, E.K.1    Yang, J.2    Park, M.Y.3
  • 58
    • 84862101815 scopus 로고    scopus 로고
    • Crystallization process systems. An imprint of
    • ISBN 0 7506 5520 8
    • Joes AG. Crystallization process systems. An imprint of Elsevier Science 2002;ISBN 0 7506 5520 8
    • (2002) Elsevier Science
    • Joes, A.G.1
  • 59
  • 62
    • 0038184026 scopus 로고    scopus 로고
    • Micellization of block copolymers
    • Riess GR. Micellization of block copolymers. Prog Polym Sci 2003;28:1107-70
    • (2003) Prog Polym Sci , vol.28 , pp. 1107-1170
    • Riess, G.R.1
  • 63
    • 33745346800 scopus 로고    scopus 로고
    • Shell cross-linked stearic acid grafted chitosan oligosaccharide self-aggregated micelles for controlled release of paclitaxel
    • DOI 10.1016/j.colsurfb.2006.04.009, PII S092777650600141X
    • Hu FQ, Ren GF, Yuan H, et al. Shell cross-linked stearic acid grafted chitosan oligosaccharide self-aggregated micelles for controlled release of paclitaxel. Colloids Surf B Biointerfaces 2006;50(2):97-103 (Pubitemid 43946659)
    • (2006) Colloids and Surfaces B: Biointerfaces , vol.50 , Issue.2 , pp. 97-103
    • Hu, F.-Q.1    Ren, G.-F.2    Yuan, H.3    Du, Y.-Z.4    Zeng, S.5
  • 64
    • 84862102383 scopus 로고    scopus 로고
    • Surfactants and polymers in drug delivery
    • ISBN-13: 978-0824708047
    • Malmsten M. Surfactants and polymers in drug delivery. Informa Healthcare; 2002;ISBN-13: 978-0824708047
    • (2002) Informa Healthcare
    • Malmsten, M.1
  • 66
    • 34548609979 scopus 로고    scopus 로고
    • β-Lapachone-containing PEG-PLA polymer micelles as novel nanotherapeutics against NQO1-overexpressing tumor cells
    • DOI 10.1016/j.jconrel.2007.04.014, PII S0168365907001897, Proceedings of the Thirtheenth International Symposium on Recent Advances in Drug Delivery Systems
    • Blanco E, Bey EA, Dong Y, et al. Beta-lapachone-containing PEG-PLA polymer micelles as novel nanotherapeutics against NQO1-overexpressing tumor cells. J Control Release 2007;122(3):365-74 (Pubitemid 47404665)
    • (2007) Journal of Controlled Release , vol.122 , Issue.3 , pp. 365-374
    • Blanco, E.1    Bey, E.A.2    Dong, Y.3    Weinberg, B.D.4    Sutton, D.M.5    Boothman, D.A.6    Gao, J.7
  • 67
    • 42949124511 scopus 로고    scopus 로고
    • Solubilization of hydrophobic drugs by methoxy poly(Ethylene Clycol)-blockpolycaprolactone diblock copolymer micelles: Theoretical and experimental data and correlations
    • Letchford K, Liggins R, Burt H. Solubilization of hydrophobic drugs by methoxy poly(Ethylene Clycol)-blockpolycaprolactone diblock copolymer micelles: theoretical and experimental data and correlations. Paharmacetics Preformulation Drug Deliv 2007;97(3):1179-91
    • (2007) Paharmacetics Preformulation Drug Deliv , vol.97 , Issue.3 , pp. 1179-1191
    • Letchford, K.1    Liggins, R.2    Burt, H.3
  • 68
    • 0346494420 scopus 로고    scopus 로고
    • Polymer-Drug Compatibility: A Guide to the Development of Delivery Systems for the Anticancer Agent, Ellipticine
    • DOI 10.1002/jps.10533
    • Liu J, Xiao Y, Allen C. Polymer-drug compatibility: a guide to the development of delivery systems for the anticancer agent. J Pharm Sci 2004;93:132-43 (Pubitemid 38081821)
    • (2004) Journal of Pharmaceutical Sciences , vol.93 , Issue.1 , pp. 132-143
    • Liu, J.1    Xiao, Y.2    Allen, C.3
  • 69
    • 34547907626 scopus 로고    scopus 로고
    • Indomethacin-loaded polymeric nanocarriers based on amphiphilic polyphosphazenes with poly (N-isopropylacrylamide) and ethyl tryptophan as side groups: Preparation, in vitro and in vivo evaluation
    • DOI 10.1016/j.jconrel.2006.09.013, PII S0168365906004652
    • Zhang JX, Li XJ, Qiu LY, et al. Indomethacin-loaded polymeric nanocarriers based on amphiphilic polyphosphazenes with poly (N-isopropylacrylamide) and ethyl tryptophan as side groups: preparation, in vitro and in vivo evaluation. J Control Release 2006;116(3):322-9 (Pubitemid 44827410)
    • (2006) Journal of Controlled Release , vol.116 , Issue.3 , pp. 322-329
    • Zhang, J.X.1    Li, X.J.2    Qiu, L.Y.3    Li, X.H.4    Yan, M.Q.5    Yi Jin6    Zhu, K.J.7
  • 70
    • 19344369608 scopus 로고    scopus 로고
    • Synthesis of a novel PEG-block-poly(aspartic acid-stat-phenylalanine) copolymer shows potential for formation of a micellar drug carrier
    • DOI 10.1016/j.ijpharm.2005.02.025, PII S0378517305001572
    • Prompruk K, Govender T, Zhang S, et al. Synthesis of a novel PEG-blockpoly( aspartic acid-stat-phenylalanine) copolymer shows potential for formation of a micellar drug carrier. Int J Pharm 2005;297(1-2):242-53 (Pubitemid 40720283)
    • (2005) International Journal of Pharmaceutics , vol.297 , Issue.1-2 , pp. 242-253
    • Prompruk, K.1    Govender, T.2    Zhang, S.3    Xiong, C.D.4    Stolnik, S.5
  • 71
    • 40649100957 scopus 로고    scopus 로고
    • Antitumor efficacy of cisplatin-loaded glycol chitosan nanoparticles in tumor-bearing mice
    • Kim JH, Kim YS, Park K, et al. Antitumor efficacy of cisplatin-loaded glycol chitosan nanoparticles in tumor-bearing mice. J Control Release 2008;127(1):41-9
    • (2008) J Control Release , vol.127 , Issue.1 , pp. 41-49
    • Kim, J.H.1    Kim, Y.S.2    Park, K.3
  • 72
    • 38349038224 scopus 로고    scopus 로고
    • Pharmacokinetics, biodistribution, efficacy and safety of N-octyl-O-sulfate chitosan micelles loaded with paclitaxel
    • Zhang C, Qu G, Sun Y, et al. Pharmacokinetics, biodistribution, efficacy and safety of N-octyl-O-sulfate chitosan micelles loaded with paclitaxel. Biomaterials 2008;29(9):1233-41
    • (2008) Biomaterials , vol.29 , Issue.9 , pp. 1233-1241
    • Zhang, C.1    Qu, G.2    Sun, Y.3
  • 73
    • 0035850224 scopus 로고    scopus 로고
    • Structure and design of polymeric surfactant-based drug delivery systems
    • DOI 10.1016/S0168-3659(01)00299-1, PII S0168365901002991
    • Torchilin VP. Structure and design of polymeric surfactant-based drug delivery systems. J Control Release 2001;73(2-3):137-72 (Pubitemid 32544594)
    • (2001) Journal of Controlled Release , vol.73 , Issue.2-3 , pp. 137-172
    • Torchilin, V.P.1
  • 74
    • 73649133678 scopus 로고    scopus 로고
    • Overcoming the barriers in micellar drug delivery: Loading efficiency, in vivo stability, and micelle-cell interaction
    • Kim S, Shi Y, Kim JY, et al. Overcoming the barriers in micellar drug delivery: loading efficiency, in vivo stability, and micelle-cell interaction. Expert Opin Drug Deliv 2010;7(1):49-62
    • (2010) Expert Opin Drug Deliv , vol.7 , Issue.1 , pp. 49-62
    • Kim, S.1    Shi, Y.2    Kim, J.Y.3
  • 75
    • 79952950503 scopus 로고    scopus 로고
    • Stearic acid-g-chitosan polymeric micelle for oral drug delivery: In vitro transport and in vivo absorption
    • Yuan H, Lu LJ, Du YZ, et al. Stearic acid-g-chitosan polymeric micelle for oral drug delivery: in vitro transport and in vivo absorption. Mol Pharm 2011;8(1):225-38
    • (2011) Mol Pharm , vol.8 , Issue.1 , pp. 225-238
    • Yuan, H.1    Lu, L.J.2    Du, Y.Z.3
  • 76
    • 62849083225 scopus 로고    scopus 로고
    • Synthesis and evaluation of lauryl succinyl chitosan particles towards oral insulin delivery and absorption
    • Rekha MR, Sharma CP. Synthesis and evaluation of lauryl succinyl chitosan particles towards oral insulin delivery and absorption. J Control Release 2009;135(2):144-51
    • (2009) J Control Release , vol.135 , Issue.2 , pp. 144-151
    • Rekha, M.R.1    Sharma, C.P.2
  • 77
    • 40949091885 scopus 로고    scopus 로고
    • Nanoaggregate of thermosensitive chitosan-pluronic for sustained release of hydrophobic drug
    • Park KM, Bae JW, Joung YK, et al. Nanoaggregate of thermosensitive chitosan-pluronic for sustained release of hydrophobic drug. Colloids Surf B Biointerfaces 2008;63(1):1-6
    • (2008) Colloids Surf B Biointerfaces , vol.63 , Issue.1 , pp. 1-6
    • Park, K.M.1    Bae, J.W.2    Joung, Y.K.3
  • 78
    • 33750480862 scopus 로고    scopus 로고
    • Shell-crosslinked Pluronic L121 micelles as a drug delivery vehicle
    • Yang TF, Chen CN, Chen MC, et al. Shell-crosslinked Pluronic L121 micelles as a drug delivery vehicle. Biomaterials 2007;28(4):725-34
    • (2007) Biomaterials , vol.28 , Issue.4 , pp. 725-734
    • Yang, T.F.1    Chen, C.N.2    Chen, M.C.3
  • 79
    • 0033120873 scopus 로고    scopus 로고
    • Transcellular uptake mechanisms of the intestinal epithelial barrier - Part one
    • DOI 10.1016/S1461-5347(99)00142-X, PII S146153479900142X
    • Daugherty AL, Mrsny RJ. Transcellular uptake mechanisms of the intestinal epithelial barrier part one. Pharm Sci Technol Today 1999;4(2):144-51 (Pubitemid 29195747)
    • (1999) Pharmaceutical Science and Technology Today , vol.2 , Issue.4 , pp. 144-151
    • Daugherty, A.L.1    Mrsny, R.J.2
  • 80
    • 0032403463 scopus 로고    scopus 로고
    • The effect of physical barriers and properties on the oral absorption of particulates
    • DOI 10.1016/S0169-409X(98)00037-4, PII S0169409X98000374
    • Norris DA, Puri N, Sinko PJ. The effect of physical barriers and properties on the oral absorption of particulates. Adv Drug Deliv Rev 1998;34(2-3):135-54 (Pubitemid 28535109)
    • (1998) Advanced Drug Delivery Reviews , vol.34 , Issue.2-3 , pp. 135-154
    • Norris, D.A.1    Puri, N.2    Sinko, P.J.3
  • 83
    • 33344463203 scopus 로고    scopus 로고
    • Intestinal uptake and biodistribution of novel polymeric micelles after oral administration
    • DOI 10.1016/j.jconrel.2005.11.012, PII S0168365905006553
    • Mathot F, van Beijsterveldt L, Preat V, et al. Intestinal uptake and biodistribution of novel polymeric micelles after oral administration. J Control Release 2006;111(1-2):47-55 (Pubitemid 43289994)
    • (2006) Journal of Controlled Release , vol.111 , Issue.1-2 , pp. 47-55
    • Mathot, F.1    Van Beijsterveldt, L.2    Preat, V.3    Brewster, M.4    Arien, A.5
  • 84
    • 50249129610 scopus 로고    scopus 로고
    • Permeation enhancer effect of chitosan and chitosan derivatives: Comparison of formulations as soluble polymers and nanoparticulate systems on insulin absorption in Caco-2 cells
    • Sadeghi AM, Dorkoosh FA, Avadi MR, et al. Permeation enhancer effect of chitosan and chitosan derivatives: comparison of formulations as soluble polymers and nanoparticulate systems on insulin absorption in Caco-2 cells. Eur JPharm Biopharm 2008;70(1):270-8
    • (2008) Eur JPharm Biopharm , vol.70 , Issue.1 , pp. 270-278
    • Sadeghi, A.M.1    Dorkoosh, F.A.2    Avadi, M.R.3
  • 85
    • 26644447977 scopus 로고    scopus 로고
    • Novel mucoadhesion tests for polymers and polymer-coated particles to design optimal mucoadhesive drug delivery systems
    • DOI 10.1016/j.addr.2005.07.008, PII S0169409X05001419, Mucoadhesive Polymers: Strategies, Achievements and Future Challenges
    • Takeuchi H, Thongborisute J, Matsui Y, et al. Novel mucoadhesion tests for polymers and polymer-coated particles to design optimal mucoadhesive drug delivery systems. Adv Drug Deliv Rev 2005;57(11):1583-94 (Pubitemid 41443471)
    • (2005) Advanced Drug Delivery Reviews , vol.57 , Issue.11 , pp. 1583-1594
    • Takeuchi, H.1    Thongborisute, J.2    Matsui, Y.3    Sugihara, H.4    Yamamoto, H.5    Kawashima, Y.6
  • 86
    • 11744298337 scopus 로고    scopus 로고
    • Hyaluronan: Preparation, structure, properties, and applications
    • Lapcik L Jr, Lapcik L, De Smedt S, et al. Hyaluronan: preparation, structure, properties, and applications. Chem Rev 1998;98(8):2663-84
    • (1998) Chem Rev , vol.98 , Issue.8 , pp. 2663-2684
    • Lapcik Jr., L.1    Lapcik, L.2    De Smedt, S.3
  • 87
    • 0035813752 scopus 로고    scopus 로고
    • Oral drug absorption enhancement by chitosan and its derivatives
    • DOI 10.1016/S0169-409X(01)00231-9, PII S0169409X01002319
    • Thanou M, Verhoef JC, Junginger HE. Oral drug absorption enhancement by chitosan and its derivatives. Adv Drug Deliv Rev 2001;52(2):117-26 (Pubitemid 33079167)
    • (2001) Advanced Drug Delivery Reviews , vol.52 , Issue.2 , pp. 117-126
    • Thanou, M.1    Verhoef, J.C.2    Junginger, H.E.3
  • 88
    • 0037261361 scopus 로고    scopus 로고
    • Enhanced oral bioavailability of paclitaxel by coadministration of the p-glycoprotein inhibitor KR30031
    • DOI 10.1023/A:1022286422439
    • Woo JS, Lee CH, Shim CK, et al. Enhanced oral bioavailability of paclitaxel by coadministration of the P-glycoprotein inhibitor KR30031. Pharm Res 2003;20(1):24-30 (Pubitemid 36152913)
    • (2003) Pharmaceutical Research , vol.20 , Issue.1 , pp. 24-30
    • Woo, J.S.1    Lee, C.H.2    Shim, C.K.3    Hwang, S.-J.4
  • 89
    • 30944456923 scopus 로고    scopus 로고
    • Application of TPGS in polymeric nanoparticulate drug delivery system
    • DOI 10.1016/j.colsurfb.2005.08.016, PII S0927776505002742
    • Mu L, Seow PH. Application of TPGS in polymeric nanoparticulate drug delivery system. Colloids Surf B Biointerfaces 2006;47(1):90-7 (Pubitemid 43111610)
    • (2006) Colloids and Surfaces B: Biointerfaces , vol.47 , Issue.1 , pp. 90-97
    • Mu, L.1    Seow, P.H.2
  • 90
    • 84900759469 scopus 로고    scopus 로고
    • Springer Dordrecht Heidelberg London New York, ISBN: 978-1-4419 0199-6
    • Andreas BS. Oral delivery of macromolecular drugs. Springer Dordrecht Heidelberg London New York 2009;ISBN: 978-1-4419-0199-6
    • (2009) Oral Delivery of Macromolecular Drugs
    • Andreas, B.S.1
  • 94
    • 49649127608 scopus 로고    scopus 로고
    • Uptake of oleoyl-chitosan nanoparticles by A549 cells
    • Zhang J, Chen XG, Peng WB, et al. Uptake of oleoyl-chitosan nanoparticles by A549 cells. Nanomedicine 2008;4(3):208-14
    • (2008) Nanomedicine , vol.4 , Issue.3 , pp. 208-214
    • Zhang, J.1    Chen, X.G.2    Peng, W.B.3
  • 96
    • 70350622459 scopus 로고    scopus 로고
    • In vivo antitumor effects of chitosan-conjugated docetaxel after oral administration
    • Lee E, Kim H, Lee IH, et al. In vivo antitumor effects of chitosan-conjugated docetaxel after oral administration. J Control Release 2009;140(2):79-85
    • (2009) J Control Release , vol.140 , Issue.2 , pp. 79-85
    • Lee, E.1    Kim, H.2    Lee, I.H.3
  • 97
    • 84876198463 scopus 로고    scopus 로고
    • Tocol modified glycol chitosan for the oral delivery of poorly soluble drugs
    • Duhem N, Rolland J, Riva R, et al. Tocol modified glycol chitosan for the oral delivery of poorly soluble drugs. Int J Pharm 2011
    • (2011) Int J Pharm
    • Duhem, N.1    Rolland, J.2    Riva, R.3
  • 98
    • 78149342494 scopus 로고    scopus 로고
    • Enhanced oral absorption of paclitaxel in N-deoxycholic acid-N, O-hydroxyethyl chitosan micellar system
    • Li H, Huo M, Zhou J, et al. Enhanced oral absorption of paclitaxel in N-deoxycholic acid-N, O-hydroxyethyl chitosan micellar system. J Pharm Sci 2010;99(11):4543-53
    • (2010) J Pharm Sci , vol.99 , Issue.11 , pp. 4543-4553
    • Li, H.1    Huo, M.2    Zhou, J.3
  • 99
    • 67349137876 scopus 로고    scopus 로고
    • Paclitaxel-loaded Pluronic P123/ F127 mixed polymeric micelles: Formulation, optimization and in vitro characterization
    • Wei Z, Hao J, Yuan S, et al. Paclitaxel-loaded Pluronic P123/ F127 mixed polymeric micelles: formulation, optimization and in vitro characterization. Int J Pharm 2009;376(1-2):176-85
    • (2009) Int J Pharm , vol.376 , Issue.1-2 , pp. 176-185
    • Wei, Z.1    Hao, J.2    Yuan, S.3
  • 100
    • 67549094625 scopus 로고    scopus 로고
    • Preparation and properties of hydroxycamptothecin-loaded nanoparticles made of amphiphilic copolymer and normal polymer
    • Wang J, Wang R, Li LB. Preparation and properties of hydroxycamptothecin- loaded nanoparticles made of amphiphilic copolymer and normal polymer. J Colloid Interface Sci 2009;336(2):808-13
    • (2009) J Colloid Interface Sci , vol.336 , Issue.2 , pp. 808-813
    • Wang, J.1    Wang, R.2    Li, L.B.3
  • 101
    • 27844496561 scopus 로고    scopus 로고
    • Mixed micelles made of poly(ethylene glycol)-phosphatidylethanolamine conjugate and D-α-tocopheryl polyethylene glycol 1000 succinate as pharmaceutical nanocarriers for camptothecin
    • DOI 10.1016/j.ijpharm.2005.08.026, PII S0378517305006083
    • Mu L, Elbayoumi TA, Torchilin VP. Mixed micelles made of poly(ethylene glycol)-phosphatidylethanolamine conjugate and d-alpha-tocopheryl polyethylene glycol 1000 succinate as pharmaceutical nanocarriers for camptothecin. Int J Pharm 2005;306(1-2):142-9 (Pubitemid 41643148)
    • (2005) International Journal of Pharmaceutics , vol.306 , Issue.1-2 , pp. 142-149
    • Mu, L.1    Elbayoumi, T.A.2    Torchilin, V.P.3
  • 102
    • 77957880781 scopus 로고    scopus 로고
    • Poly (L-lactide)-vitamin e TPGS nanoparticles enhanced the cytotoxicity of doxorubicin in drug-resistant MCF-7 breast cancer cells
    • Li PY, Lai PS, Hung WC, et al. Poly (L-lactide)-vitamin E TPGS nanoparticles enhanced the cytotoxicity of doxorubicin in drug-resistant MCF-7 breast cancer cells. Biomacromolecules 2010;11(10):2576-82
    • (2010) Biomacromolecules , vol.11 , Issue.10 , pp. 2576-2582
    • Li, P.Y.1    Lai, P.S.2    Hung, W.C.3
  • 103
    • 24644459310 scopus 로고    scopus 로고
    • Nanoparticles of poly(lactide)/vitamin E TPGS copolymer for cancer chemotherapy: Synthesis, formulation, characterization and in vitro drug release
    • DOI 10.1016/j.biomaterials.2005.05.104, PII S0142961205004977
    • Zhang Z, Feng SS. Nanoparticles of poly (lactide)/vitamin E TPGS copolymer for cancer chemotherapy: synthesis, formulation, characterization and in vitro drug release. Biomaterials 2006;27(2):262-70 (Pubitemid 41278528)
    • (2006) Biomaterials , vol.27 , Issue.2 , pp. 262-270
    • Zhang, Z.1    Feng, S.-S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.