A simple method for the preparation of PEG-6-mercaptopurine for oral administration

Bioorganic and Medicinal Chemistry Letters

Volumn 17, Issue 23, 2007, Pages 6607-6609

  Zacchigna, Marina ^a   Cateni, Francesca ^a   Di Luca, Gabriella ^a   Drioli, Sara ^a  

^a UNIVERSITY OF TRIESTE   (Italy)

Author keywords

6 Mercaptopurine; 6 MP; CsF Celite; PEG; Polyethylene glycol; Prodrug

Indexed keywords

AZATHIOPRINE; MACROGOL; MACROGOL 6000; MERCAPTOPURINE; PEG 6 MERCAPTOPURINE; THIOL GROUP; UNCLASSIFIED DRUG;

AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG STABILITY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; IN VITRO STUDY; IN VIVO STUDY; METABOLIC ACTIVATION;

6-MERCAPTOPURINE; ADMINISTRATION, ORAL; DRUG DELIVERY SYSTEMS; HUMANS; POLYETHYLENE GLYCOLS; PRODRUGS;

EID: 35648954063     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2007.09.064     Document Type: Article

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