Modulation of red blood cell aggregation and blood viscosity by the covalent attachment of pluronic copolymers

Biorheology

Volumn 38, Issue 2-3, 2001, Pages 239-247

  Armstrong, J K ^a   Meiselman, H J ^a   Wenby, R B ^a   Fisher, T C ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Aggregation; Covalent; Micellization; Pluronic; Poloxamer; Red blood cell

Indexed keywords

COPOLYMER; POLOXAMER;

ARTICLE; ARTIFACT; BLOOD RHEOLOGY; BLOOD VISCOSITY; COVALENT BOND; ERYTHROCYTE AGGREGATION; ERYTHROCYTE MEMBRANE; HUMAN; MICELLE; NORMAL HUMAN;

BLOOD VISCOSITY; CELL CULTURE TECHNIQUES; ERYTHROCYTE AGGREGATION; HEMORHEOLOGY; HUMANS; MICELLES; MOLECULAR WEIGHT; POLOXAMER; STRESS, MECHANICAL; SURFACE-ACTIVE AGENTS; TEMPERATURE;

EID: 0034966350     PISSN: 0006355X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (35)

1. Alteration of immunological properties of bovine serum albumin by covalent attachment of polyethylene glycol
2. Poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) block-copolymer surfactants in aqueous-solutions and at interfaces - Thermodynamics, structure, dynamics, and modeling
3. Self-aggregation and phase-behavior of poly(ethylene oxide) poly(propylene oxide) poly(ethylene oxide) block-copolymers in aqueous-solution
4. Scanning microcalorimetry as a tool to interpret the effects of poloxamers on erythrocyte aggregation
5. The effects of poloxamers on erythrocyte aggregation as a function of temperature
6. Covalent binding of poly(ethylene glycol) (PEG) to the surface of red blood cells inhibits aggregation and reduces low shear blood viscosity
7. Evidence against macromolecular "bridging" as the mechanism of red blood cell aggregation induced by nonionic polymers
8. Standard aggregating media to test the "aggregability" of rat red blood cells
9. An investigation of dilute aqueous-solution behavior of poly(oxyethylene) + poly(oxypropylene) + poly(oxyethylene) block-copolymers
10. Polyethylene glycol-coated red-blood cells fail to bind glycophorin A-specific antibodies and are impervious to invasion by the Plasmodiumfalciparum malaria parasite
11. Effects of dextran-induced hyperviscosity on regional blood flow and hemodynamics in dogs
12. Differential scanning calorimetry - Applications in biotechnology
13. Effects of red blood cell hyperaggregation on the rat microcirculation blood flow
14. Modification of the red blood cell to alter aggregation - A useful tool for hemorheology studies
15. PEG-coated red blood cells - Simplifying blood transfusion in the new millenium?
16. The influence of polyethylene oxide on the aggregation of erythrocytes
17. The effect of osmotic pressure of aqueous PEG solutions on red blood cells
18. Progress toward preparation of universal donor red cells
19. Red cell interactions in macromolecular suspension
20. The disaggregation effect of dextran 40 on red cell aggregation in macromolecular suspensions
21. Pharmacokinetics of RheothRx Injection in healthy male volunteers
22. A phase III multicenter, randomized, double-blind, placebo-controlled study of Flocor (purified poloxamer 188) in patients with sickle cell disease in acute vaso-occlusive crisis
23. Blood rheology in vitro and in vivo
24. Inhibition and acceleration of erythrocyte aggregation induced by small macromolecules
25. Randomized, controlled trial of RheothRx (poloxamer 188) in patients with suspected acute myocardial infarction
26. Rheology of blood
27. Observed differences in dextran and polyvinylpyrrolidone as rouleaux-inducing agents
28. Quantitative evaluation of flow dynamics of erythrocytes in microvessels: Influence of erythrocyte aggregation
29. Biochemical applications of differential scanning calorimetry
30. Effects of RheothRx on mortality and morbidity, left ventricular function, and infarct size in patients with acute myocardial infarction