Using thioamides to site-specifically interrogate the dynamics of hydrogen bond formation in β-sheet folding

Journal of the American Chemical Society

Volumn 134, Issue 19, 2012, Pages 8026-8029

  Culik, Robert M ^a   Jo, Hyunil ^b   Degrado, William F ^b   Gai, Feng ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DYNAMIC ROLES; FOLDING KINETICS; FOLDING RATES; FOLDING TRANSITION STATE; H-BONDS; HYDROGEN BOND ACCEPTORS; HYDROGEN-BOND FORMATION; PROTEIN FOLDING MECHANISMS; SITE-SPECIFIC; THIOAMIDES;

AMINO ACIDS; PROTEIN FOLDING;

HYDROGEN BONDS;

THIOAMIDE; TRYPTOPHAN;

ARTICLE; BETA SHEET; HYDROGEN BOND; MOLECULAR DYNAMICS; MOLECULAR PROBE; MUTATION; PROTEIN ANALYSIS; PROTEIN FOLDING; PROTEIN STRUCTURE; SYNTHESIS;

AMINO ACID SEQUENCE; HYDROGEN BONDING; MODELS, MOLECULAR; PEPTIDE FRAGMENTS; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN UNFOLDING; THIOAMIDES; TIME FACTORS;

EID: 84862062006     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja301681v     Document Type: Article

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