Inhibition of key enzymes linked to type 2 diabetes and sodium nitroprusside-induced lipid peroxidation in rat pancreas by water extractable phytochemicals from some tropical spices

Pharmaceutical Biology

Volumn 50, Issue 7, 2012, Pages 857-865

  Adefegha, Stephen Adeniyi ^a   Oboh, Ganiyu ^a  

^a FEDERAL UNIVERSITY OF TECHNOLOGY   (Nigeria)

Author keywords

Amylase; glucosidase; inhibition; lipid peroxidation; pancreas; tropical spices

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; AFRAMOMUM DANIELLI EXTRACT; AFRAMOMUM MELEGUETA EXTRACT; ALPHA GLUCOSIDASE; AMYLASE; FLAVONOID; FREE RADICAL; MONODORA MYRISTICA EXTRACT; NITROPRUSSIDE SODIUM; PHENOL DERIVATIVE; PIPER GUINEENSE EXTRACT; PLANT EXTRACT; SYZYGIUM AROMATICUM EXTRACT; THIOBARBITURIC ACID REACTIVE SUBSTANCE; UNCLASSIFIED DRUG; WATER; XYLOPIA AETHIOPICA EXTRACT;

AFRAMOMUM DANIELLI; AFRAMOMUM MELEGUETA; ANIMAL TISSUE; ANNONACEAE; ANTIDIABETIC ACTIVITY; AQUEOUS SOLUTION; ARTICLE; CLOVE; DISEASE ASSOCIATION; DRUG SCREENING; ENZYME INHIBITION; FLOWER; FRUIT; IC 50; IN VITRO STUDY; INHIBITION KINETICS; LIPID PEROXIDATION; MONODORA MYRISTICA; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS; PHYTOCHEMISTRY; PLANT LEAF; RAT; SPECTROPHOTOMETRY; SPICE; XYLOPIA; XYLOPIA AETHIOPICA; ZINGIBERACEAE;

ALPHA-AMYLASES; ALPHA-GLUCOSIDASES; ANIMALS; DIABETES MELLITUS, TYPE 2; ENZYME INHIBITORS; LIPID PEROXIDATION; NITROPRUSSIDE; PANCREAS; PLANT COMPONENTS, AERIAL; PLANT EXTRACTS; RATS; RATS, WISTAR; SPICES;

AFRAMOMUM DANIELLII; AFRAMOMUM MELEGUETA; ANNONACEAE; MONODORA MYRISTICA; MYRTACEAE; PIPER GUINEENSE; PIPERACEAE; RATTUS; SYZYGIUM AROMATICUM; XYLOPIA AETHIOPICA; ZINGIBERACEAE;

EID: 84862003630     PISSN: 13880209     EISSN: 17445116     Source Type: Journal    
DOI: 10.3109/13880209.2011.641022     Document Type: Article

References (62)

1. Abesundara KJ, Matsui T, Matsumoto K. (2004). α-Glucosidase inhibitory activity of some Sri Lanka plant extracts, one of which, Cassia auriculata, exerts a strong antihyperglycemic effect in rats comparable to the therapeutic drug acarbose. J Agric Food Chem, 52, 2541-2545.
2. Ali H, Houghton PJ, Soumyanath A. (2006). α-Amylase inhibitory activity of some Malaysian plants used to treat diabetes; with particular reference to Phyllanthus amarus. J Ethnopharmacol, 107, 449-455. (Pubitemid 44363032)
3. Amic D, Davidovic-Amic D, Beslo D, Trinajstic N. (2003). Structure-radical scavenging activity relationship of flavonoids. Croat Chem Acta, 76, 55-61. (Pubitemid 38353178)
4. Apostolidis E, Kwon YI, Shetty K. (2007). Inhibitory potential of herb, fruit, and fungal-enriched cheese against key enzymes linked to type 2 diabetes and hypertension. Innov Food Sci Emerg Technol, 4, 46-54. (Pubitemid 46217979)
5. Bellé NA, Dalmolin GD, Fonini G, Rubin MA, Rocha JB. (2004). Polyamines reduces lipid peroxidation induced by different prooxidant agents. Brain Res, 1008, 245-251. (Pubitemid 38624055)
6. Bernfield P. (1951). Enzymes of starch degradation and synthesis. Adv Enzymol, 12, 379-428.
7. Bhadari MR, Jong-Anarakkan N, Hong G, Kawabata J. (2008). α-Glucosidase and α-amylase inhibitory activities of Nepalese medicinal herb Pakhanbhed (Bergenia ciliata Haw). Food Chem, 106, 247-252. (Pubitemid 47332112)
8. Bischoff H. (1994). Pharmacology of alpha-glucosidase inhibition. Eur J Clin Invest, 24, 3-10.
9. Bravo L. (1998). Polyphenols: Chemistry, dietary sources, metabolism, and nutritional significance. Nutr Rev, 56, 317-333.
10. Brownlee M. (2005). The pathobiology of diabetic complications: A unifying mechanism. Diabetes, 54, 1615-1625.
11. Brownlee M, Cerami A. (1981). The biochemistry of the complications of diabetes mellitus. Annu Rev Biochem, 50, 385-432.
12. Cheplick S, Kwon Y, Bhowmik P, Shetty K. (2007). Clonal variation in raspberry fruit phenolics and relevance for diabetes and hypertension management. J Food Biochem, 31, 656-679. (Pubitemid 47364670)
13. Chu YF, Sun J, Wu X, Liu RH. (2002). Antioxidant and antiproliferative activities of common vegetables. J Agric Food Chem, 50, 6910-6916. (Pubitemid 35253192)
14. Doherty VF, Olaniran OO, Kanife UC. (2010). Antimicrobial activities of Aframomum melegueta (Alligator pepper). Int J Biol, 2, 126-131.
15. Evans JL, Goldfine ID, Maddux BA, Grodsky GM. (2003). Are oxidative stress-activated signaling pathways mediators of insulin resistance and β-cell dysfunction? Diabetes, 52, 1-8. (Pubitemid 36042100)
16. Ezekwesili CN, Nwodo OFC, Eneh FU, Ogbunugafor HA. (2010). Investigation of the chemical composition and biological activity of Xylopia aethiopica Dunal (Annonacae). Afr J Biotechnol, 9, 7352-7356.
17. Fasoyiro SB, Adegoke GO, Idowu OO. (2006). Characterization and partial purification of antioxidant component of ethereal fractions of Aframomum danielli. World J Chem, 1, 1-5.
18. Gerich JE. (2003). Clinical significance, pathogenesis, and management of postprandial hyperglycemia. Arch Intern Med, 163, 1306-1316.
19. Gyamfi MA, Yonamine M, Aniya Y. (1999). Free-radical scavenging action of medicinal herbs from Ghana: Thonningia sanguinea on experimentally-induced liver injuries. Gen Pharmacol, 32, 661-667. (Pubitemid 29287176)
20. Horii S, Fukase H, Matsuo T, Kameda Y, Asano N, Matsui K. (1986). Synthesis and α-D-glucosidase inhibitory activity of N-substituted valiolamine derivatives as potential oral antidiabetic agents. J Med Chem, 29, 1038-1046. (Pubitemid 16068813)
21. Johnston KL, Clifford MN, Morgan LM. (2003). Coffee acutely modifies gastrointestinal hormone secretion and glucose tolerance in humans: Glycemic effects of chlorogenic acid and caffeine. Am J Clin Nutr, 78, 728-733. (Pubitemid 39663490)
22. Kaisserlian CE, Razzouq N, Astier A, Paul M. (2005). Sodium nitroprusside stability at 1 μg/mL in aqueous solutions. Eur J Hosp Pharm Sci, 11, 88-90.
23. Kawamura M, Heinecke JW, Chait A. (1994). Pathophysiological concentrations of glucose promote oxidative modification of low density lipoprotein by a superoxide-dependent pathway. J Clin Invest, 94, 771-778. (Pubitemid 24251010)
24. Kim JS, Kwon CS, Son KH. (2000). Inhibition of α-glucosidase and amylase by luteolin, a flavonoid. Biosci Biotechnol Biochem, 64, 2458-2461.
25. Kwon YI, Jang HD, Shetty K. (2006). Evaluation of Rhodiola crenulata and Rhodiola rosea for management of type II diabetes and hypertension. Asia Pac J Clin Nutr, 15, 425-432.
26. Kwon YI, Apostolidis E, Kim YC, Shetty K. (2007). Health benefits of traditional corn, beans, and pumpkin: In vitro studies for hyperglycemia and hypertension management. J Med Food, 10, 266-275. (Pubitemid 47105671)
27. Maritim AC, Sanders RA, Watkins JB 3rd. (2003). Diabetes, oxidative stress, and antioxidants: A review. J Biochem Mol Toxicol, 17, 24-38. (Pubitemid 36410972)
28. Matsui T, Ueda T, Oki T, Sugita K, Terahara N, Matsumoto K. (2001). α-glucosidase inhibitory action of natural acylated anthocyanins. 2. α-glucosidase inhibition by isolated acylated anthocyanins. J Agric Food Chem, 49, 1952-1956. (Pubitemid 32816844)
29. Matsumoto N, Ishigaki F, Ishigaki A, Iwashina H, Hara Y. (1993). Reduction of blood glucose levels by tea catechin. Biosci Biotechnol Biochem, 57, 525-527.
30. McCue P, Kwon YI, Shetty K. (2005). Anti-diabetic and anti-hypertensive potential of sprouted and solid-state bioprocessed soybean. Asia Pac J Clin Nutr, 14, 145-152. (Pubitemid 40769783)
31. McDougall GJ, Shpiro F, Dobson P, Smith P, Blake A, Stewart D. (2005). Different polyphenolic components of soft fruits inhibit α-amylase and α-glucosidase. J Agric Food Chem, 53, 2760-2766. (Pubitemid 40471760)
32. Meda A, Lamien CE, Romito M, Millogom J, Nacoulma OG. (2005). Determination of the total phenolic, flavonoid and proline contents in Burkina Faso honey, as well as their radical scavenging activity. Food Chem, 91, 571-577. (Pubitemid 40023291)
33. Nickavar B, Yousefian N. (2009). Inhibitory effects of six Allium species on α-amylase enzyme activity. Iranian J Pharm Res, 8, 53-57.
34. Niedowicz DM, Daleke DL. (2005). The role of oxidative stress in diabetic complications. Cell Biochem Biophys, 43, 289-330. (Pubitemid 41095268)
35. Oberley LW. (1988). Free radicals and diabetes. Free Radic Biol Med, 5, 113-124.
36. 2+-induced lipid peroxidation in brain-in vitro. Food Chem, 102, 178-185.
37. Oboh G, Rocha JBT. (2007). Antioxidant in foods: A New Challenge for Food Processors: Leading Edge Antioxidants Research. New York US: Nova Science Publishers Inc; 35-64.
38. Oboh G, Raddatz H, Henle T. (2008). Antioxidant properties of polar and non-polar extracts of some tropical green leafy vegetables. J Sci Food Agric, 88, 2486-2492.
39. Oboh G, Akinyemi AJ, Ademiluyi AO, Adefegha SA. (2010a). Inhibitory effects of aqueous extract of two varieties of ginger on some key enzymes linked to type-2 diabetes in vitro. J Food Nutr Res, 49, 14-20.
40. Oboh G, Akomolafe TL, Adefegha SA, Adetuyi AO. (2010b). Antioxidant and modulatory effect of ethanolic extract of Madagascar Harungana (Harungana madagascariensis) bark on cyclophosphamide induced neurotoxicity in rats. J Food Drug Anal, 18, 171-179.
41. Ogbera O. (2007). Burden of diabetic illness in an urban hospital in Nigeria. Trop Doct, 37, 153-154.
42. Ogbera AO, Chinenye S, Onyekwere A, Fasanmade O. (2007). Prognostic indices of diabetes mortality. Ethn Dis, 17, 721-725. (Pubitemid 350156798)
43. Ohkawa H, Ohishi N, Yagi K. (1979). Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem, 95, 351-358. (Pubitemid 9194347)
44. Olonisakin A, Oladimeji MO, Lajide L. (2006). Chemical composition and antibacterial activity of steam distilled oil of Ashanti Pepper (Piper guineense) fruits (berries). Electr J Environ Agric Food Chem, 5, 1531-1535.
45. Ortiz-Andrade RR, García-Jiménez S, Castillo-España P, Ramírez-Avila G, Villalobos-Molina R, Estrada-Soto S. (2007). α-Glucosidase inhibitory activity of the methanolic extract from Tournefortia hartwegiana: An anti-hyperglycemic agent. J Ethnopharmacol, 109, 48-53. (Pubitemid 44889199)
46. Pinto Mda S, Ranilla LG, Apostolidis E, Lajolo FM, Genovese MI, Shetty K. (2009). Evaluation of antihyperglycemia and antihypertension potential of native Peruvian fruits using in vitro models. J Med Food, 12, 278-291.
47. Pinto MD, Kwon YI, Apostolidis E, Lajolo FM, Genovese MI, Shetty K. (2010). Evaluation of red currants (Ribes rubrum L), black currants (Ribes nigrum L.), red and green gooseberries (Ribes uva-crispa) for potential management of type 2 diabetes and hypertension using in vitro models. J Food Biochem, 34, 639-660.
48. Ranilla LG, Kwon YI, Apostolidis E, Shetty K. (2010). Phenolic compounds, antioxidant activity and in vitro inhibitory potential against key enzymes relevant for hyperglycemia and hypertension of commonly used medicinal plants, herbs and spices in Latin America. Bioresour Technol, 101, 4676-4689.
49. Rosca MG, Mustata TG, Kinter MT, Ozdemir AM, Kern TS, Szweda LI, Brownlee M, Monnier VM, Weiss MF. (2005). Glycation of mitochondrial proteins from diabetic rat kidney is associated with excess superoxide formation. Am J Physiol Renal Physiol, 289, 420-430.
50. Scalbert A, Manach C, Morand C, Rémésy C, Jiménez L. (2005). Dietary polyphenols and the prevention of diseases. Crit Rev Food Sci Nutr, 45, 287-306. (Pubitemid 41657352)
51. Shim YJ, Doo HK, Ahn SY, Kim YS, Seong JK, Park IS, Min BH. (2003). Inhibitory effect of aqueous extract from the gall of Rhus chinensis on α-glucosidase activity and postprandial blood glucose. J Ethnopharmacol, 85, 283-287.
52. Singleton V L, Orthofer R, Lamuela-Raventos RM. (1999). Analysis of total phenols and other oxidation substrates and antioxidants by means of Folin-Ciocalteu reagent. Method in Enzymol, 299, 152-178. (Pubitemid 28483890)
53. Sun J, Chu YF, Wu X, Liu RH. (2002). Antioxidant and antiproliferative activities of common fruits. J Agric Food Chem, 50, 7449-7454. (Pubitemid 35424917)
54. Trease GE, Evans W C. (1983). Pharmacognosy. 12th edition. London, Britain: Bailliere, Tindal, pp 469-470.
55. Uwakwe AA, Nwaoguikpe RN. (2008). In vitro antisickling effects of Xylopia aethiopica and Monodora myristica. J Med Plants Res, 2, 119-124.
56. Varon J, Marik PE. (2000). The diagnosis and management of hypertensive crises. Chest, 118, 214-27. (Pubitemid 30485512)
57. Wang H, Du YJ, Song HC. (2010). α-glucosidase and α-amylase inhibitory activities of guava leaves. Food Chem, 123, 6-13.
58. Weyer C, Funahashi T, Tanaka S, Hotta K, Matsuzawa Y, Pratley RE, Tataranni PA. (2001). Hypoadiponectinemia in obesity and type 2 diabetes: Close association with insulin resistance and hyperinsulinemia. J Clin Endocrinol Metab, 86, 1930-1935. (Pubitemid 32472900)
59. Wojdyło A, Oszmian'ski J, Czemerys R. (2007). Antioxidant activity and phenolic compounds in 32 selected herbs. Food Chem, 105, 940-949. (Pubitemid 47079088)
60. World Health Organization Consultation. Definition, Diagnosis and Classification of Diabetes Mellitus and its Complications, Part 1: Diagnosis and Classification of Diabetes Mellitus. Report of a WHO Consultation. Geneva: World Health Organization; 1999.
61. Ye X, Song C, Yuan P, Mao R. (2010). α-Glucosidase and α-amylase inhibitory activity of common constituents from traditional Chinese medicine used for diabetes mellitus. Chin J Nat Med, 8, 349-352.
62. Zar JH. (1984). Biostatistical Analysis. USA: Prentice-Hall, Inc.; 620.