The inflammasome mediates hyperoxia-induced alveolar cell permeability

Journal of Immunology

Volumn 184, Issue 10, 2010, Pages 5819-5826

  Kolliputi, Narasaiah ^a,b   Shaik, Rahamthulla S ^a   Waxman, Aaron B ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b UNIVERSITY OF SOUTH FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; INFLAMMASOME; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; PURINERGIC P2X7 RECEPTOR; PURINERGIC RECEPTOR BLOCKING AGENT; PURINERGIC RECEPTOR STIMULATING AGENT; SHORT HAIRPIN RNA; AUTACOID; POTASSIUM;

ACUTE LUNG INJURY; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL DEATH; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; ENZYME ACTIVATION; ENZYME INDUCTION; HYPEROXIA; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; INFLAMMATORY CELL; LUNG ALVEOLUS CELL; LUNG ALVEOLUS MACROPHAGE; MOUSE; NONHUMAN; POTASSIUM TRANSPORT; PRIORITY JOURNAL; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CELL CULTURE; COCULTURE; IMMUNOLOGY; LUNG ALVEOLUS; METABOLISM; PATHOLOGY; PHYSIOLOGY; PROTEIN PROCESSING; PROTEIN TRANSPORT; RESPIRATORY TRACT MUCOSA;

ACUTE LUNG INJURY; ADENOSINE TRIPHOSPHATE; ANIMALS; CELL MEMBRANE PERMEABILITY; CELLS, CULTURED; COCULTURE TECHNIQUES; HYPEROXIA; INFLAMMATION MEDIATORS; INTERLEUKIN-1BETA; MACROPHAGES, ALVEOLAR; MICE; MICE, INBRED C57BL; POTASSIUM; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN TRANSPORT; PULMONARY ALVEOLI; RESPIRATORY MUCOSA;

EID: 77954750716     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0902766     Document Type: Article

References (36)

1. Waxman, A. B., O. Einarsson, T. Seres, R. G. Knickelbein, J. B. Warshaw, R. Johnston, R. J. Homer, and J. A. Elias. 1998. Targeted lung expression of interleukin-11 enhances murine tolerance of 100% oxygen and diminishes hyperoxia-induced DNA fragmentation. J. Clin. Invest. 101: 1970-1982.
2. Ward, N. S., A. B.Waxman, R. J. Homer, L. L. Mantell, O. Einarsson, Y. Du, and J. A. Elias. 2000. Interleukin-6-induced protection in hyperoxic acute lung injury. Am. J. Respir. Cell Mol. Biol. 22: 535-542.
3. He, C. H., A. B. Waxman, C. G. Lee, H. Link, M. E. Rabach, B. Ma, Q. Chen, Z. Zhu, M. Zhong, K. Nakayama, et al. 2005. Bcl-2-related protein A1 is an endogenous and cytokine-stimulated mediator of cytoprotection in hyperoxic acute lung injury. J. Clin. Invest. 115: 1039-1048.
4. Ganter, M. T., J. Roux, B. Miyazawa, M. Howard, J. A. Frank, G. Su, D. Sheppard, S. M. Violette, P. H. Weinreb, G. S. Horan, et al. 2008. Interleukin- 1beta causes acute lung injury via alphavbeta5 and alphavbeta6 integrindependent mechanisms. Circ. Res. 102: 804-812.
5. Mariathasan, S., and D. M. Monack. 2007. Inflammasome adaptors and sensors: intracellular regulators of infection and inflammation. Nat. Rev. Immunol. 7: 31-40.
6. Ogura, Y., F. S. Sutterwala, and R. A. Flavell. 2006. The inflammasome: first line of the immune response to cell stress. Cell 126: 659-662. (Pubitemid 44233635)
7. Dostert, C., V. Pétrilli, R. Van Bruggen, C. Steele, B. T. Mossman, and J. Tschopp. 2008. Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica. Science 320: 674-677.
8. Gasse, P., C. Mary, I. Guenon, N. Noulin, S. Charron, S. Schnyder-Candrian, B. Schnyder, S. Akira, V. F. Quesniaux, V. Lagente, et al. 2007. IL-1R1/MyD88 signaling and the inflammasome are essential in pulmonary inflammation and fibrosis in mice. J. Clin. Invest. 117: 3786-3799.
9. Di Virgilio, F. 2007. Liaisons dangereuses: P2X(7) and the inflammasome. Trends Pharmacol. Sci. 28: 465-472.
10. Sutterwala, F. S., Y. Ogura, and R. A. Flavell. 2007. The inflammasome in pathogen recognition and inflammation. J. Leukoc. Biol. 82: 259-264.
11. Drenth, J. P., and J. W. van der Meer. 2006. The inflammasome - a linebacker of innate defense. N. Engl. J. Med. 355: 730-732.
12. Kolliputi, N., and A. B. Waxman. 2009. IL-6 cytoprotection in hyperoxic acute lung injury occurs via suppressor of cytokine signaling-1-induced apoptosis signal-regulating kinase-1 degradation. Am. J. Respir. Cell Mol. Biol. 40: 314-324.
13. Kolliputi, N., and A. B. Waxman. 2009. IL-6 cytoprotection in hyperoxic acute lung injury occurs via PI3K/Akt-mediated Bax phosphorylation. Am. J. Physiol. Lung Cell. Mol. Physiol. 297: L6-L16.
14. Waxman, A. B., and N. Kolliputi. 2009. IL-6 protects against hyperoxia-induced mitochondrial damage via Bcl-2-induced Bak interactions with mitofusins. Am. J. Respir. Cell Mol. Biol. 41: 385-396.
15. Lavnikova, N., S. Prokhorova, L. Helyar, and D. L. Laskin. 1993. Isolation and partial characterization of subpopulations of alveolar macrophages, granulocytes, and highly enriched interstitial macrophages from rat lung. Am. J. Respir. Cell Mol. Biol. 8: 384-392.
16. Kahlenberg, J. M., and G. R. Dubyak. 2004. Mechanisms of caspase-1 activation by P2X7 receptor-mediated K+ release. Am. J. Physiol. Cell Physiol. 286: C1100-C1108.
17. Sutterwala, F. S., Y. Ogura, M. Szczepanik, M. Lara-Tejero, G. S. Lichtenberger, E. P. Grant, J. Bertin, A. J. Coyle, J. E. Galán, P. W. Askenase, and R. A. Flavell. 2006. Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1. Immunity 24: 317-327.
18. Bruey, J. M., N. Bruey-Sedano, F. Luciano, D. Zhai, R. Balpai, C. Xu, C. L. Kress, B. Bailly-Maitre, X. Li, A. Osterman, et al. 2007. Bcl-2 and Bcl-XL regulate proinflammatory caspase-1 activation by interaction with NALP1. Cell 129: 45-56.
19. Franchi, L., T. D. Kanneganti, G. R. Dubyak, and G. Núñez. 2007. Differential requirement of P2X7 receptor and intracellular K+ for caspase-1 activation induced by intracellular and extracellular bacteria. J. Biol. Chem. 282: 18810-18818.
20. Elssner, A., M. Duncan, M. Gavrilin, and M. D. Wewers. 2004. A novel P2X7 receptor activator, the human cathelicidin-derived peptide LL37, induces IL-1 beta processing and release. J. Immunol. 172: 4987-4994. (Pubitemid 38456425)
21. Barker, G. F., N. D. Manzo, K. L. Cotich, R. K. Shone, and A. B. Waxman. 2006. DNA damage induced by hyperoxia: quantitation and correlation with lung injury. Am. J. Respir. Cell Mol. Biol. 35: 277-288.
22. Hennige, A. M., N. Lembert, M. A. Wahl, and H. P. Ammon. 2000. Oxidative stress increases potassium efflux from pancreatic islets by depletion of intracellular calcium stores. Free Radic. Res. 33: 507-516.
23. Mariathasan, S., D. S. Weiss, K. Newton, J. McBride, K. O'Rourke, M. Roose-Girma, W. P. Lee, Y. Weinrauch, D. M. Monack, and V. M. Dixit. 2006. Cryopyrin activates the inflammasome in response to toxins and ATP. Nature 440: 228-232.
24. Frank, J. A., C. M. Wray, D. F. McAuley, R. Schwendener, and M. A.Matthay. 2006. Alveolar macrophages contribute to alveolar barrier dysfunction in ventilator-induced lung injury. Am. J. Physiol. Lung Cell. Mol. Physiol. 291: L1191-L1198.
25. Ahmad, K. A., K. B. Iskandar, J. L. Hirpara, M. V. Clement, and S. Pervaiz. 2004. Hydrogen peroxide-mediated cytosolic acidification is a signal for mitochondrial translocation of Bax during drug-induced apoptosis of tumor cells. Cancer Res. 64: 7867-7878.
26. Petrilli, V., S. Papin, and J. Tschopp. 2005. The inflammasome. Curr. Biol. 15: R581.
27. Pétrilli, V., S. Papin, C. Dostert, A. Mayor, F. Martinon, and J. Tschopp. 2007. Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration. Cell Death Differ. 14: 1583-1589.
28. Hjort, M. R., A. J. Brenyo, J. N. Finkelstein, M. W. Frampton, M. B. LoMonaco, J. C. Stewart, C. J. Johnston, and C. T. D'Angio. 2003. Alveolar epithelial cell-macrophage interactions affect oxygen-stimulated interleukin-8 release. Inflammation 27: 137-145.
29. Gaca, J. G., D. Palestrant, D. J. Lukes, M. Olausson, W. Parker, and R. D. Davis, Jr. 2003. Prevention of acute lung injury in swine: depletion of pulmonary intravascular macrophages using liposomal clodronate. J. Surg. Res. 112: 19-25.
30. Goodman, R. B., J. Pugin, J. S. Lee, and M. A. Matthay. 2003. Cytokine-mediated inflammation in acute lung injury. Cytokine Growth Factor Rev. 14: 523-535. (Pubitemid 37296025)
31. Abulafia, D. P., J. P. de Rivero Vaccari, J. D. Lozano, G. Lotocki, R. W. Keane, and W. D. Dietrich. 2009. Inhibition of the inflammasome complex reduces the inflammatory response after thromboembolic stroke in mice. J. Cereb. Blood Flow Metab. 29: 534-544.
32. Lister, M. F., J. Sharkey, D. A. Sawatzky, J. P. Hodgkiss, D. J. Davidson, A. G. Rossi, and K. Finlayson. 2007. The role of the purinergic P2X7 receptor in inflammation. J. Inflamm. (Lond.) 4: 5 .
33. Gottlieb, R. 2005. ICE-ing the heart. Circ. Res. 96: 1036-1038.
34. Saleh, M., and D. R. Green. 2007. Caspase-1 inflammasomes: choosing between death and taxis. Cell Death Differ. 14: 1559-1560.
35. Wewers, M. D., and A. Sarkar. 2009. P2X(7) receptor and macrophage function. Purinergic Signal. 5: 189-195.
36. Noguchi, T., K. Ishii, H. Fukutomi, I. Naguro, A. Matsuzawa, K. Takeda, and H. Ichijo. 2008. Requirement of reactive oxygen species-dependent activation of ASK1-p38 MAPK pathway for extracellular ATP-induced apoptosis in macrophage. J. Biol. Chem. 283: 7657-7665.