-
1
-
-
0038725685
-
Negative selection - clearing out the bad apples from the T-cell repertoire
-
Palmer E. Negative selection - clearing out the bad apples from the T-cell repertoire. Nat Rev Immunol 2003; 3:383-91.
-
(2003)
Nat Rev Immunol
, vol.3
, pp. 383-391
-
-
Palmer, E.1
-
2
-
-
0035313978
-
Signal strength in thymic selection and lineage commitment
-
Hogquist KA. Signal strength in thymic selection and lineage commitment. Curr Opin Immunol 2001; 13:225-31.
-
(2001)
Curr Opin Immunol
, vol.13
, pp. 225-231
-
-
Hogquist, K.A.1
-
3
-
-
0028208488
-
Peptides in positive and negative selection: a delicate balance
-
Allen PM. Peptides in positive and negative selection: a delicate balance. Cell 1994; 76:593-6.
-
(1994)
Cell
, vol.76
, pp. 593-596
-
-
Allen, P.M.1
-
5
-
-
0033491636
-
T lymphocyte tolerance: from thymic deletion to peripheral control mechanisms
-
Stockinger B. T lymphocyte tolerance: from thymic deletion to peripheral control mechanisms. Adv Immunol 1999; 71:229-65.
-
(1999)
Adv Immunol
, vol.71
, pp. 229-265
-
-
Stockinger, B.1
-
6
-
-
62249131518
-
Complete but curtailed T-cell response to very low-affinity antigen
-
Zehn D, Lee SY, Bevan MJ. Complete but curtailed T-cell response to very low-affinity antigen. Nature 2009; 458:211-4.
-
(2009)
Nature
, vol.458
, pp. 211-214
-
-
Zehn, D.1
Lee, S.Y.2
Bevan, M.J.3
-
7
-
-
0033118739
-
A kinetic basis for T cell receptor repertoire selection during an immune response
-
Savage PA, Boniface JJ, Davis MM. A kinetic basis for T cell receptor repertoire selection during an immune response. Immunity 1999; 10:485-92.
-
(1999)
Immunity
, vol.10
, pp. 485-492
-
-
Savage, P.A.1
Boniface, J.J.2
Davis, M.M.3
-
8
-
-
78649398891
-
Nature and nurture: T-cell receptor-dependent and T-cell receptor-independent differentiation cues in the selection of the memory T-cell pool
-
Kim C, Williams MA. Nature and nurture: T-cell receptor-dependent and T-cell receptor-independent differentiation cues in the selection of the memory T-cell pool. Immunology 2010; 131:310-7.
-
(2010)
Immunology
, vol.131
, pp. 310-317
-
-
Kim, C.1
Williams, M.A.2
-
9
-
-
0036884742
-
Progressive differentiation and selection of the fittest in the immune response
-
Lanzavecchia A, Sallusto F. Progressive differentiation and selection of the fittest in the immune response. Nat Rev Immunol 2002; 2:982-7.
-
(2002)
Nat Rev Immunol
, vol.2
, pp. 982-987
-
-
Lanzavecchia, A.1
Sallusto, F.2
-
10
-
-
8444236620
-
Clonal selection of helper T cells is determined by an affinity threshold with no further skewing of TCR binding properties
-
Malherbe L, Hausl C, Teyton L, McHeyzer-Williams MG. Clonal selection of helper T cells is determined by an affinity threshold with no further skewing of TCR binding properties. Immunity 2004; 21:669-79.
-
(2004)
Immunity
, vol.21
, pp. 669-679
-
-
Malherbe, L.1
Hausl, C.2
Teyton, L.3
McHeyzer-Williams, M.G.4
-
12
-
-
0035320679
-
+ regulatory T cells induced by an agonist self-peptide
-
+ regulatory T cells induced by an agonist self-peptide. Nat Immunol 2001; 2:301-6.
-
(2001)
Nat Immunol
, vol.2
, pp. 301-306
-
-
Jordan, M.S.1
Boesteanu, A.2
Reed, A.J.3
Petrone, A.L.4
Holenbeck, A.E.5
Lerman, M.A.6
Naji, A.7
Caton, A.J.8
-
14
-
-
0026681679
-
The T cell receptor as a multicomponent signalling machine: CD4/CD8 coreceptors and CD45 in T cell activation
-
Janeway CA Jr. The T cell receptor as a multicomponent signalling machine: CD4/CD8 coreceptors and CD45 in T cell activation. Annu Rev Immunol 1992; 10:645-74.
-
(1992)
Annu Rev Immunol
, vol.10
, pp. 645-674
-
-
Janeway Jr., C.A.1
-
17
-
-
0028178784
-
T cell receptor antagonist peptides induce positive selection
-
Hogquist KA, Jameson SC, Heath WR, Howard JL, Bevan MJ, Carbone FR. T cell receptor antagonist peptides induce positive selection. Cell 1994; 76:17-27.
-
(1994)
Cell
, vol.76
, pp. 17-27
-
-
Hogquist, K.A.1
Jameson, S.C.2
Heath, W.R.3
Howard, J.L.4
Bevan, M.J.5
Carbone, F.R.6
-
18
-
-
0033577859
-
A kinetic threshold between negative and positive selection based on the longevity of the T cell receptor-ligand complex
-
Williams CB, Engle DL, Kersh GJ, White JM, Allen PM. A kinetic threshold between negative and positive selection based on the longevity of the T cell receptor-ligand complex. J Exp Med 1999; 189:1531-44.
-
(1999)
J Exp Med
, vol.189
, pp. 1531-1544
-
-
Williams, C.B.1
Engle, D.L.2
Kersh, G.J.3
White, J.M.4
Allen, P.M.5
-
19
-
-
34250642773
-
Generation of T-cell receptor retrogenic mice
-
Holst J, Szymczak-Workman AL, Vignali KM, Burton AR, Workman CJ, Vignali DA. Generation of T-cell receptor retrogenic mice. Nat Protoc 2006; 1:406-17.
-
(2006)
Nat Protoc
, vol.1
, pp. 406-417
-
-
Holst, J.1
Szymczak-Workman, A.L.2
Vignali, K.M.3
Burton, A.R.4
Workman, C.J.5
Vignali, D.A.6
-
20
-
-
33646356743
-
Rapid analysis of T-cell selection in vivo using T cell-receptor retrogenic mice
-
Holst J, Vignali KM, Burton AR, Vignali DA. Rapid analysis of T-cell selection in vivo using T cell-receptor retrogenic mice. Nat Methods 2006; 3:191-7.
-
(2006)
Nat Methods
, vol.3
, pp. 191-197
-
-
Holst, J.1
Vignali, K.M.2
Burton, A.R.3
Vignali, D.A.4
-
21
-
-
0035015174
-
Analysis of the aphthovirus 2A/2B polyprotein 'cleavage' mechanism indicates not a proteolytic reaction, but a novel translational effect: a putative ribosomal 'skip'
-
Donnelly ML, Luke G, Mehrotra A, Li X, Hughes LE, Gani D, Ryan MD. Analysis of the aphthovirus 2A/2B polyprotein 'cleavage' mechanism indicates not a proteolytic reaction, but a novel translational effect: a putative ribosomal 'skip'. J Gen Virol 2001; 82(Pt 5): 1013-25.
-
(2001)
J Gen Virol
, vol.82
, Issue.PART 5
, pp. 1013-1025
-
-
Donnelly, M.L.1
Luke, G.2
Mehrotra, A.3
Li, X.4
Hughes, L.E.5
Gani, D.6
Ryan, M.D.7
-
22
-
-
0035005706
-
The 'cleavage' activities of foot-and-mouth disease virus 2A site-directed mutants and naturally occurring '2A-like' sequences
-
Donnelly ML, Hughes LE, Luke G, Mendoza H, ten Dam E, Gani D, Ryan MD. The 'cleavage' activities of foot-and-mouth disease virus 2A site-directed mutants and naturally occurring '2A-like' sequences. J Gen Virol 2001; 82(Pt 5): 1027-41.
-
(2001)
J Gen Virol
, vol.82
, Issue.PART 5
, pp. 1027-1041
-
-
Donnelly, M.L.1
Hughes, L.E.2
Luke, G.3
Mendoza, H.4
ten Dam, E.5
Gani, D.6
Ryan, M.D.7
-
23
-
-
16344365811
-
Skipping the co-expression problem: the new 2A "CHYSEL" technology
-
de Felipe P. Skipping the co-expression problem: the new 2A "CHYSEL" technology. Genet Vaccines Ther 2004; 2:13.
-
(2004)
Genet Vaccines Ther
, vol.2
, pp. 13
-
-
de Felipe, P.1
-
24
-
-
34249092656
-
A case for "StopGo": reprogramming translation to augment codon meaning of GGN by promoting unconventional termination (Stop) after addition of glycine and then allowing continued translation (Go)
-
Atkins JF, Wills NM, Loughran G, Wu CY, Parsawar K, Ryan MD, Wang CH, Nelson CC. A case for "StopGo": reprogramming translation to augment codon meaning of GGN by promoting unconventional termination (Stop) after addition of glycine and then allowing continued translation (Go). RNA 2007; 13:803-10.
-
(2007)
RNA
, vol.13
, pp. 803-810
-
-
Atkins, J.F.1
Wills, N.M.2
Loughran, G.3
Wu, C.Y.4
Parsawar, K.5
Ryan, M.D.6
Wang, C.H.7
Nelson, C.C.8
-
25
-
-
46149120568
-
Site-specific release of nascent chains from ribosomes at a sense codon
-
Doronina VA, Wu C, de Felipe P, Sachs MS, Ryan MD, Brown JD. Site-specific release of nascent chains from ribosomes at a sense codon. Mol Cell Biol 2008; 28:4227-39.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 4227-4239
-
-
Doronina, V.A.1
Wu, C.2
de Felipe, P.3
Sachs, M.S.4
Ryan, M.D.5
Brown, J.D.6
-
26
-
-
20344377636
-
Development of 2A peptide-based strategies in the design of multicistronic vectors
-
Szymczak AL, Vignali DA. Development of 2A peptide-based strategies in the design of multicistronic vectors. Expert Opin Biol Ther 2005; 5:627-38.
-
(2005)
Expert Opin Biol Ther
, vol.5
, pp. 627-638
-
-
Szymczak, A.L.1
Vignali, D.A.2
-
27
-
-
0034990345
-
Retroviral vector-mediated expression of HoxB4 in hematopoietic cells using a novel coexpression strategy
-
Klump H, Schiedlmeier B, Vogt B, Ryan M, Ostertag W, Baum C. Retroviral vector-mediated expression of HoxB4 in hematopoietic cells using a novel coexpression strategy. Gene Ther 2001; 8:811-7.
-
(2001)
Gene Ther
, vol.8
, pp. 811-817
-
-
Klump, H.1
Schiedlmeier, B.2
Vogt, B.3
Ryan, M.4
Ostertag, W.5
Baum, C.6
-
28
-
-
2342471959
-
Correction of multi-gene deficiency in vivo using a single 'self-cleaving' 2A peptide-based retroviral vector
-
Szymczak AL, Workman CJ, Wang Y, Vignali KM, Dilioglou S, Vanin EF, Vignali DA. Correction of multi-gene deficiency in vivo using a single 'self-cleaving' 2A peptide-based retroviral vector. Nat Biotechnol 2004; 22:589-94.
-
(2004)
Nat Biotechnol
, vol.22
, pp. 589-594
-
-
Szymczak, A.L.1
Workman, C.J.2
Wang, Y.3
Vignali, K.M.4
Dilioglou, S.5
Vanin, E.F.6
Vignali, D.A.7
-
30
-
-
0032946020
-
Production of interleukin-12 as a self-processing 2A polypeptide
-
Chaplin PJ, Camon EB, Villarreal-Ramos B, Flint M, Ryan MD, Collins RA. Production of interleukin-12 as a self-processing 2A polypeptide. J Interferon Cytokine Res 1999; 19:235-41.
-
(1999)
J Interferon Cytokine Res
, vol.19
, pp. 235-241
-
-
Chaplin, P.J.1
Camon, E.B.2
Villarreal-Ramos, B.3
Flint, M.4
Ryan, M.D.5
Collins, R.A.6
-
31
-
-
0029148905
-
Cancer immunotherapy of established tumors with IL-12. Effective delivery by genetically engineered fibroblasts
-
Zitvogel L, Tahara H, Robbins PD, Storkus WJ, Clarke MR, Nalesnik MA, Lotze MT. Cancer immunotherapy of established tumors with IL-12. Effective delivery by genetically engineered fibroblasts. J Immunol 1995; 155:1393-403.
-
(1995)
J Immunol
, vol.155
, pp. 1393-1403
-
-
Zitvogel, L.1
Tahara, H.2
Robbins, P.D.3
Storkus, W.J.4
Clarke, M.R.5
Nalesnik, M.A.6
Lotze, M.T.7
-
32
-
-
0029053343
-
Effective eradication of established murine tumors with IL-12 gene therapy using a polycistronic retroviral vector
-
Tahara H, Zitvogel L, Storkus WJ et al. Effective eradication of established murine tumors with IL-12 gene therapy using a polycistronic retroviral vector. J Immunol 1995; 154:6466-74.
-
(1995)
J Immunol
, vol.154
, pp. 6466-6474
-
-
Tahara, H.1
Zitvogel, L.2
Storkus, W.J.3
-
34
-
-
21244489949
-
The CD3ε proline-rich sequence, and its interaction with Nck, is not required for T cell development and function
-
Szymczak AL, Workman CJ, Gil D, Dilioglou S, Vignali KM, Palmer E, Vignali DA. The CD3ε proline-rich sequence, and its interaction with Nck, is not required for T cell development and function. J Immunol 2005; 175:270-5.
-
(2005)
J Immunol
, vol.175
, pp. 270-275
-
-
Szymczak, A.L.1
Workman, C.J.2
Gil, D.3
Dilioglou, S.4
Vignali, K.M.5
Palmer, E.6
Vignali, D.A.7
-
35
-
-
15444362930
-
Plasticity and rigidity in adaptor protein-2-mediated internalization of the TCR:CD3 complex
-
Szymczak AL, Vignali DA. Plasticity and rigidity in adaptor protein-2-mediated internalization of the TCR:CD3 complex. J Immunol 2005; 174:4153-60.
-
(2005)
J Immunol
, vol.174
, pp. 4153-4160
-
-
Szymczak, A.L.1
Vignali, D.A.2
-
36
-
-
77950532705
-
Tonic ubiquitylation controls T-cell receptor: CD3 complex expression during T-cell development
-
Wang H, Holst J, Woo SR et al. Tonic ubiquitylation controls T-cell receptor: CD3 complex expression during T-cell development. EMBO J 2010; 29:1285-98.
-
(2010)
EMBO J
, vol.29
, pp. 1285-1298
-
-
Wang, H.1
Holst, J.2
Woo, S.R.3
-
37
-
-
40449142562
-
Public T cell receptor β-chains are not advantaged during positive selection
-
Furmanski AL, Ferreira C, Bartok I et al. Public T cell receptor β-chains are not advantaged during positive selection. J Immunol 2008; 180:1029-39.
-
(2008)
J Immunol
, vol.180
, pp. 1029-1039
-
-
Furmanski, A.L.1
Ferreira, C.2
Bartok, I.3
-
38
-
-
77950628737
-
T cell receptor CDR3 loops influence αβ pairing
-
Bartok I, Holland SJ, Kessels HW, Silk JD, Alkhinji M, Dyson J. T cell receptor CDR3 loops influence αβ pairing. Mol Immunol 2010; 8:1613-8.
-
(2010)
Mol Immunol
, vol.8
, pp. 1613-1618
-
-
Bartok, I.1
Holland, S.J.2
Kessels, H.W.3
Silk, J.D.4
Alkhinji, M.5
Dyson, J.6
-
39
-
-
44049096285
-
Scalable signaling mediated by T cell antigen receptor-CD3 ITAMs ensures effective negative selection and prevents autoimmunity
-
Holst J, Wang H, Eder KD et al. Scalable signaling mediated by T cell antigen receptor-CD3 ITAMs ensures effective negative selection and prevents autoimmunity. Nat Immunol 2008; 9:658-66.
-
(2008)
Nat Immunol
, vol.9
, pp. 658-666
-
-
Holst, J.1
Wang, H.2
Eder, K.D.3
-
40
-
-
4344622052
-
Diabetes incidence is unaltered in glutamate decarboxylase 65-specific TCR retrogenic nonobese diabetic mice: generation by retroviral-mediated stem cell gene transfer
-
Arnold PY, Burton AR, Vignali DA. Diabetes incidence is unaltered in glutamate decarboxylase 65-specific TCR retrogenic nonobese diabetic mice: generation by retroviral-mediated stem cell gene transfer. J Immunol 2004; 173:3103-11.
-
(2004)
J Immunol
, vol.173
, pp. 3103-3111
-
-
Arnold, P.Y.1
Burton, A.R.2
Vignali, D.A.3
-
41
-
-
48449094511
-
On the pathogenicity of autoantigen-specific T-cell receptors
-
Burton AR, Vincent E, Arnold PY et al. On the pathogenicity of autoantigen-specific T-cell receptors. Diabetes 2008; 57:1321-30.
-
(2008)
Diabetes
, vol.57
, pp. 1321-1330
-
-
Burton, A.R.1
Vincent, E.2
Arnold, P.Y.3
-
43
-
-
70349745490
-
T cell islet accumulation in type 1 diabetes is a tightly regulated, cell-autonomous event
-
Lennon GP, Bettini M, Burton AR, Vincent E, Arnold PY, Santamaria P, Vignali DA. T cell islet accumulation in type 1 diabetes is a tightly regulated, cell-autonomous event. Immunity 2009; 31:643-53.
-
(2009)
Immunity
, vol.31
, pp. 643-653
-
-
Lennon, G.P.1
Bettini, M.2
Burton, A.R.3
Vincent, E.4
Arnold, P.Y.5
Santamaria, P.6
Vignali, D.A.7
-
44
-
-
0037197973
-
Generation of functional antigen-specific T cells in defined genetic backgrounds by retrovirus-mediated expression of TCR cDNAs in hematopoietic precursor cells
-
Yang L, Qin XF, Baltimore D, Van Parijs L. Generation of functional antigen-specific T cells in defined genetic backgrounds by retrovirus-mediated expression of TCR cDNAs in hematopoietic precursor cells. Proc Natl Acad Sci U S A 2002; 99:6204-9.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 6204-6209
-
-
Yang, L.1
Qin, X.F.2
Baltimore, D.3
Van Parijs, L.4
-
45
-
-
15444378447
-
Long-term in vivo provision of antigen-specific T cell immunity by programming hematopoietic stem cells
-
Yang L, Baltimore D. Long-term in vivo provision of antigen-specific T cell immunity by programming hematopoietic stem cells. Proc Natl Acad Sci U S A 2005; 102:4518-23.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 4518-4523
-
-
Yang, L.1
Baltimore, D.2
-
46
-
-
47949106921
-
Retrogenic modeling of experimental allergic encephalomyelitis associates T cell frequency but not TCR functional affinity with pathogenicity
-
Alli R, Nguyen P, Geiger TL. Retrogenic modeling of experimental allergic encephalomyelitis associates T cell frequency but not TCR functional affinity with pathogenicity. J Immunol 2008; 181:136-45.
-
(2008)
J Immunol
, vol.181
, pp. 136-145
-
-
Alli, R.1
Nguyen, P.2
Geiger, T.L.3
-
47
-
-
43049173734
-
Rapid identification of MHC class I-restricted antigens relevant to autoimmune diabetes using retrogenic T cells
-
Chaparro RJ, Burton AR, Serreze DV, Vignali DA, DiLorenzo TP. Rapid identification of MHC class I-restricted antigens relevant to autoimmune diabetes using retrogenic T cells. J Immunol Methods 2008; 2:106-15.
-
(2008)
J Immunol Methods
, vol.2
, pp. 106-115
-
-
Chaparro, R.J.1
Burton, A.R.2
Serreze, D.V.3
Vignali, D.A.4
DiLorenzo, T.P.5
-
48
-
-
48249109500
-
Conserved T cell receptor α-chain induces insulin autoantibodies
-
Kobayashi M, Jasinski J, Liu E et al. Conserved T cell receptor α-chain induces insulin autoantibodies. Proc Natl Acad Sci U S A 2008; 105:10090-4.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 10090-10094
-
-
Kobayashi, M.1
Jasinski, J.2
Liu, E.3
-
49
-
-
79955495219
-
Thymus-specific serine protease controls autoreactive CD4 T cell development and autoimmune diabetes in mice
-
Viret C, Leung-Theung-Long S, Serre L, Lamare C, Vignali DA, Malissen B, Carrier A, Guerder S. Thymus-specific serine protease controls autoreactive CD4 T cell development and autoimmune diabetes in mice. J Clin Invest 2011; 121:1810-21.
-
(2011)
J Clin Invest
, vol.121
, pp. 1810-1821
-
-
Viret, C.1
Leung-Theung-Long, S.2
Serre, L.3
Lamare, C.4
Vignali, D.A.5
Malissen, B.6
Carrier, A.7
Guerder, S.8
-
50
-
-
33751572636
-
+ T cells respond to Chlamydia trachomatis in the genital mucosa
-
+ T cells respond to Chlamydia trachomatis in the genital mucosa. J Immunol 2006; 177:7974-9.
-
(2006)
J Immunol
, vol.177
, pp. 7974-7979
-
-
Roan, N.R.1
Starnbach, M.N.2
-
51
-
-
68249162543
-
T cell receptor CDR2 β and CDR3 β loops collaborate functionally to shape the iNKT cell repertoire
-
Mallevaey T, Scott-Browne JP, Matsuda JL et al. T cell receptor CDR2 β and CDR3 β loops collaborate functionally to shape the iNKT cell repertoire. Immunity 2009; 31:60-71.
-
(2009)
Immunity
, vol.31
, pp. 60-71
-
-
Mallevaey, T.1
Scott-Browne, J.P.2
Matsuda, J.L.3
-
52
-
-
76249100913
-
Peptide-specific, TCR-α-driven, coreceptor-independent negative selection in TCR-α-chain transgenic mice
-
Furmanski AL, Bartok I, Chai JG et al. Peptide-specific, TCR-α-driven, coreceptor-independent negative selection in TCR-α-chain transgenic mice. J Immunol 2010; 184:650-7.
-
(2010)
J Immunol
, vol.184
, pp. 650-657
-
-
Furmanski, A.L.1
Bartok, I.2
Chai, J.G.3
-
53
-
-
67349111962
-
Analysis of T cell receptor β chains that combine with dominant conserved TRAV5D-4*04 anti-insulin B:9-23 α chains
-
Zhang L, Jasinski JM, Kobayashi M et al. Analysis of T cell receptor β chains that combine with dominant conserved TRAV5D-4*04 anti-insulin B:9-23 α chains. J Autoimmun 2009; 33:42-9.
-
(2009)
J Autoimmun
, vol.33
, pp. 42-49
-
-
Zhang, L.1
Jasinski, J.M.2
Kobayashi, M.3
-
54
-
-
77952000041
-
γδ T cell receptors confer autonomous responsiveness to the insulin-peptide B:9-23
-
Zhang L, Jin N, Nakayama M, O'Brien RL, Eisenbarth GS, Born WK. γδ T cell receptors confer autonomous responsiveness to the insulin-peptide B:9-23. J Autoimmun 2010; 34:478-84.
-
(2010)
J Autoimmun
, vol.34
, pp. 478-484
-
-
Zhang, L.1
Jin, N.2
Nakayama, M.3
O'Brien, R.L.4
Eisenbarth, G.S.5
Born, W.K.6
-
55
-
-
0030724897
-
Spontaneous autoimmune diabetes in monoclonal T cell nonobese diabetic mice
-
Verdaguer J, Schmidt D, Amrani A, Anderson B, Averill N, Santamaria P. Spontaneous autoimmune diabetes in monoclonal T cell nonobese diabetic mice. J Exp Med 1997; 186:1663-76.
-
(1997)
J Exp Med
, vol.186
, pp. 1663-1676
-
-
Verdaguer, J.1
Schmidt, D.2
Amrani, A.3
Anderson, B.4
Averill, N.5
Santamaria, P.6
-
56
-
-
0027378612
-
Following a diabetogenic T cell from genesis through pathogenesis
-
Katz JD, Wang B, Haskins K, Benoist C, Mathis D. Following a diabetogenic T cell from genesis through pathogenesis. Cell 1993; 74:1089-100.
-
(1993)
Cell
, vol.74
, pp. 1089-1100
-
-
Katz, J.D.1
Wang, B.2
Haskins, K.3
Benoist, C.4
Mathis, D.5
-
57
-
-
33747067459
-
Transgenic insulin (B:9-23) T-cell receptor mice develop autoimmune diabetes dependent upon RAG genotype, H-2g7 homozygosity, and insulin 2 gene knockout
-
Jasinski JM, Yu L, Nakayama M, Li MM, Lipes MA, Eisenbarth GS, Liu E. Transgenic insulin (B:9-23) T-cell receptor mice develop autoimmune diabetes dependent upon RAG genotype, H-2g7 homozygosity, and insulin 2 gene knockout. Diabetes 2006; 55:1978-84.
-
(2006)
Diabetes
, vol.55
, pp. 1978-1984
-
-
Jasinski, J.M.1
Yu, L.2
Nakayama, M.3
Li, M.M.4
Lipes, M.A.5
Eisenbarth, G.S.6
Liu, E.7
-
58
-
-
78650937547
-
Paired analysis of TCRα and TCRβ chains at the single-cell level in mice
-
Dash P, McClaren JL, Oguin TH 3rd et al. Paired analysis of TCRα and TCRβ chains at the single-cell level in mice. J Clin Invest 2011; 121:288-95.
-
(2011)
J Clin Invest
, vol.121
, pp. 288-295
-
-
Dash, P.1
McClaren, J.L.2
Oguin 3rd, T.H.3
-
59
-
-
55749085634
-
Instant conditional transgenesis in the mouse hematopoietic compartment
-
Csikos T, Reijmers RM, Uren AG, Spaargaren M, Pals ST. Instant conditional transgenesis in the mouse hematopoietic compartment. J Immunol Methods 2008; 339:259-63.
-
(2008)
J Immunol Methods
, vol.339
, pp. 259-263
-
-
Csikos, T.1
Reijmers, R.M.2
Uren, A.G.3
Spaargaren, M.4
Pals, S.T.5
-
60
-
-
42149168460
-
A trans-Golgi network golgin is required for the regulated secretion of TNF in activated macrophages in vivo
-
Lieu ZZ, Lock JG, Hammond LA, La Gruta NL, Stow JL, Gleeson PA. A trans-Golgi network golgin is required for the regulated secretion of TNF in activated macrophages in vivo. Proc Natl Acad Sci U S A 2008; 105:3351-6.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 3351-3356
-
-
Lieu, Z.Z.1
Lock, J.G.2
Hammond, L.A.3
La Gruta, N.L.4
Stow, J.L.5
Gleeson, P.A.6
-
61
-
-
36549030784
-
The inhibitory cytokine IL-35 contributes to regulatory T-cell function
-
Collison LW, Workman CJ, Kuo TT et al. The inhibitory cytokine IL-35 contributes to regulatory T-cell function. Nature 2007; 450:566-9.
-
(2007)
Nature
, vol.450
, pp. 566-569
-
-
Collison, L.W.1
Workman, C.J.2
Kuo, T.T.3
-
62
-
-
77956535599
-
Redirecting T-cell specificity by introducing a tumor-specific chimeric antigen receptor
-
Jena B, Dotti G, Cooper LJ. Redirecting T-cell specificity by introducing a tumor-specific chimeric antigen receptor. Blood 2010; 116:1035-44.
-
(2010)
Blood
, vol.116
, pp. 1035-1044
-
-
Jena, B.1
Dotti, G.2
Cooper, L.J.3
-
63
-
-
80051775476
-
T cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced leukemia
-
Kalos M, Levine BL, Porter DL, Katz S, Grupp SA, Bagg A, June CH. T cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced leukemia. Sci Transl Med 2011; 3:95ra73.
-
(2011)
Sci Transl Med
, vol.3
-
-
Kalos, M.1
Levine, B.L.2
Porter, D.L.3
Katz, S.4
Grupp, S.A.5
Bagg, A.6
June, C.H.7
-
64
-
-
84862909160
-
Antitumor activity from antigen-specific CD8 T cells generated in vivo from genetically engineered human hematopoietic stem cells
-
Vatakis DN, Koya RC, Nixon CC et al. Antitumor activity from antigen-specific CD8 T cells generated in vivo from genetically engineered human hematopoietic stem cells. Proc Natl Acad Sci U S A 2011; 108:E1408-16.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
-
-
Vatakis, D.N.1
Koya, R.C.2
Nixon, C.C.3
-
65
-
-
78649878384
-
Transplantation of mouse HSCs genetically modified to express a CD4-restricted TCR results in long-term immunity that destroys tumors and initiates spontaneous autoimmunity
-
Ha SP, Klemen ND, Kinnebrew GH et al. Transplantation of mouse HSCs genetically modified to express a CD4-restricted TCR results in long-term immunity that destroys tumors and initiates spontaneous autoimmunity. J Clin Invest 2010; 120:4273-88.
-
(2010)
J Clin Invest
, vol.120
, pp. 4273-4288
-
-
Ha, S.P.1
Klemen, N.D.2
Kinnebrew, G.H.3
-
66
-
-
40149106131
-
Lentiviral vectors encoding human immunodeficiency virus type 1 (HIV-1)-specific T-cell receptor genes efficiently convert peripheral blood CD8 T lymphocytes into cytotoxic T lymphocytes with potent in vitro and in vivo HIV-1-specific inhibitory activity
-
Joseph A, Zheng JH, Follenzi A et al. Lentiviral vectors encoding human immunodeficiency virus type 1 (HIV-1)-specific T-cell receptor genes efficiently convert peripheral blood CD8 T lymphocytes into cytotoxic T lymphocytes with potent in vitro and in vivo HIV-1-specific inhibitory activity. J Virol 2008; 82:3078-89.
-
(2008)
J Virol
, vol.82
, pp. 3078-3089
-
-
Joseph, A.1
Zheng, J.H.2
Follenzi, A.3
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