A trans-Golgi network golgin is required for the regulated secretion of TNF in activated macrophages in vivo

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 9, 2008, Pages 3351-3356

  Zi, Zhao Lieu ^a   Lock, John G ^c   Hammond, Luke A ^c   La Gruta, Nicole L ^b   Stow, Jennifer L ^c   Gleeson, Paul A ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Inflammation; Intracellular trafficking; Membrane transport; RNAi transgenic mice; TNF secretion

Indexed keywords

BIOLOGICAL MARKER; LIPOPOLYSACCHARIDE; TUMOR NECROSIS FACTOR ALPHA; AUTOANTIGEN; GOLGA4 PROTEIN, HUMAN; GOLGA4 PROTEIN, MOUSE; MEMBRANE PROTEIN; MICRORNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL MIGRATION; CELL SURFACE; CONTROLLED STUDY; ENDOSOME; GOLGI COMPLEX; HELA CELL; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; IN VIVO STUDY; INTRACELLULAR TRANSPORT; MACROPHAGE; MEMBRANE TRANSPORT; NONHUMAN; PRIORITY JOURNAL; PROTEIN SECRETION; PROTEIN TRANSPORT; UPREGULATION; ANIMAL; CELL LINE; GENETIC TRANSFECTION; GENETICS; METABOLISM; MOUSE; PHYSIOLOGY; SECRETION; TRANS GOLGI NETWORK;

MUS; MUS MUSCULUS;

ANIMALS; AUTOANTIGENS; CELL LINE; HELA CELLS; HUMANS; MACROPHAGES; MEMBRANE PROTEINS; MICE; MICRORNAS; PROTEIN TRANSPORT; TRANS-GOLGI NETWORK; TRANSFECTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 42149168460     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0800137105     Document Type: Article

References (32)

1. Hume DA (2006) The mononuclear phagocyte system. Curr Opin Immunol 18:49-53.
2. Beutler BA (1999) The role of tumor necrosis factor in health and disease. J Rheumatol 57:16-21.
3. Siddiqui MA, Scott LJ (2005) Infliximab: a review of its use in Crohn's disease and rheumatoid arthritis. Drugs 65:2179-2208.
4. Manderson AP, Kay JG, Hammond LA, Brown DL, Stow JL (2007) Subcompartments of the macrophage recycling endosome direct the differential secretion of IL-6 and TNFalpha. J Cell Biol 178:57-69.
5. Murray RZ, Kay JG, Sangermani DG, Stow JL (2005) A role for the phagosome in cytokine secretion. Science 310:1492-1495.
6. Murray RZ, Wylie FG, Khromykh T, Hume DA, Stow JL (2005) Syntaxin 6 and Vti1b form a novel SNARE complex, which is up-regulated in activated macrophages to facilitate exocytosis of tumor necrosis factor-alpha. J Biol Chem 280:10478-10483.
7. Gleeson PA, Lock JG, Luke MR, Stow JL (2004) Domains of the TGN: Coats, tethers and G proteins. Traffic 5:315-326.
8. Kooy J, Toh BH, Pettitt JM, Erlich R, Gleeson PA (1992) Human autoantibodies as reagents to conserved Golgi components - Characterization of a peripheral, 230-kDa compartment-specific Golgi protein. J Biol Chem 267:20255-20263.
9. Fritzler MJ, Lung CC, Hamel JC, Griffith KJ, Chan EKL (1995) Molecular characterization of golgin-245, a novel Golgi complex protein containing a granin signature. J Biol Chem 270:31262-31268.
10. Erlich R, Gleeson PA, Campbell P, Dietzsch E, Toh BH (1996) Molecular characterization of transGolgi p230 - A human peripheral membrane protein encoded by a gene on chromosome 6p12-22 contains extensive coiled-coil alpha-helical domains and a granin motif. J Biol Chem 271:8328-8337.
11. Gleeson PA, et al. (1996) p230 is associated with vesicles budding from the trans-Golgi network. J Cell Sci 109:2811-2821.
12. Griffith KJ, et al. (1997) Molecular cloning of a novel 97-kD golgi complex autoantigen associated with Sjogrens-syndrome. Arthritis Rheum 40:1693-1702.
13. Luke MR, Kjer-Nielsen L, Brown DL, Stow JL, Gleeson PA (2003) GRIP domain-mediated targeting of two new coiled-coil proteins, GCC88 and GCC185, to subcompartments of the trans-Golgi network. J Biol Chem 278:4216-4226.
14. Barr FA (1999) A novel Rab6-interacting domain defines a family of Golgi-targeted coiled-coil proteins. Curr Biol 9:381-384.
15. Kjer-Nielsen L, Teasdale RD, van Vliet C, Gleeson PA (1999) A novel Golgi-localisation domainshared by a class of coiled-coil peripheralmembraneproteins. Curr Biol 9:385-388.
16. Munro S, Nichols BJ (1999) The GRIP domain- a novel Golgi-targeting domain found in several coiled-coil proteins. Curr Biol 9:377-380.
17. Panic B, Whyte JR, Munro S (2003) The ARF-like GTPases Arl1p and Arl3p act in a pathway that interacts with vesicle-tethering factors at the Golgi apparatus. Curr Biol 13:405-410.
18. Gangi Setty SR, Shin ME, Yoshino A, Marks MS, Burd CG (2003) Golgi recruitment of GRIP domain proteins by Arf-like GTPase 1 is regulated by Arf-like GTPase 3. Curr Biol 13:401-404.
19. Lu L, Hong W (2003) Interaction of Arl1-GTP with GRIP domains recruits autoantigens Golgin-97 and Golgin-245/p230 onto the Golgi. Mol Biol Cell 14:3767-3781.
20. Jackson CL (2003) Membrane traffic: Arl GTPases get a GRIP on the Golgi. Curr Biol 13:R174-R176.
21. Lock JG, Hammond LA, Houghton F, Gleeson PA, Stow JL (2005) E-cadherin transport from the trans-Golgi network in tubulovesicular carriers is selectively regulated by golgin-97. Traffic 6:1142-1156.
22. Derby MC, et al. (2007) The trans-Golgi Network Golgin, GCC185, is Required for Endosome-to-Golgi Transport and Maintenance of Golgi Structure. Traffic 8:758-773.
23. Lock JG, Stow JL (2005) Rab11 in recycling endosomes regulates the sorting and basolateral transport of E-cadherin. Mol Biol Cell 16:1744-1755.
24. Derby MC, Gleeson PA (2007) New insights into membrane trafficking and protein sorting. Int Rev Cytol 261:47-116.
25. Panic B, Perisic O, Veprintsev DB, Williams RL, Munro S (2003) Structural basis for Arl1-dependent targeting of homodimeric GRIP domains to the Golgi apparatus. Mol Cell 12:863-874.
26. Price HP, Panethymitaki C, Goulding D, Smith DF (2005) Functional analysis of TbARL1, an N-myristoylated Golgi protein essential for viability in bloodstream trypanosomes. J Cell Sci 118:831-841.
27. Lieu ZZ, et al. (2007) The Golgin, GCC88, Is Required for Efficient Retrograde Transport of Cargo from the Early Endosomes to the Trans-Golgi Network. Mol Biol Cell 18:4979-4991.
28. Szymczak AL, et al. (2004) Correction of multi-gene deficiency in vivo using a single "self-cleaving" 2A peptide-based retroviral vector. Nat Biotechnol 22:589-594.
29. Evan GI, Lewis GK, Ramsay G, Bishop JM (1985) Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product. Mol Cell Biol 5:3610-3616.
30. Shurety W, Merino-Trigo A, Brown D, Hume DA, Stow JL (2000) Localization and post-Golgi trafficking of tumor necrosis factor-alpha in macrophages. J Interferon Cytokine Res 20:427-438.
31. Holst J, et al. (2006) Generation of T-cell receptor retrogenic mice. Nat Protocols 1:406-417.
32. Persons DA, et al. (1997) Retroviral-mediated transfer of the green fluorescent protein gene into murine hematopoietic cells facilitates scoring and selection of transduced progenitors in vitro and identification of genetically modified cells in vivo. Blood 90:1777-1786.