-
2
-
-
0033517155
-
CD4+ T cell division in irradiated mice requires peptides distinct from those responsible for thymic selection
-
Bender J, Mitchell T, Kappler J, Marrack P. CD4+ T cell division in irradiated mice requires peptides distinct from those responsible for thymic selection. J Exp Med 1999;190:367-374.
-
(1999)
J Exp Med
, vol.190
, pp. 367-374
-
-
Bender, J.1
Mitchell, T.2
Kappler, J.3
Marrack, P.4
-
3
-
-
0033180491
-
The peptide ligands mediating positive selection in the thymus control T cell survival and homeostatic proliferation in the periphery
-
Ernst B, Lee DS, Chang JM, Sprent J, Surh CD. The peptide ligands mediating positive selection in the thymus control T cell survival and homeostatic proliferation in the periphery. Immunity 1999;11:173-181.
-
(1999)
Immunity
, vol.11
, pp. 173-181
-
-
Ernst, B.1
Lee, D.S.2
Chang, J.M.3
Sprent, J.4
Surh, C.D.5
-
4
-
-
0036630358
-
The thymus and negative selection
-
Sprent J, Kishimoto H. The thymus and negative selection. Immunol Rev 2002;185:126-135.
-
(2002)
Immunol Rev
, vol.185
, pp. 126-135
-
-
Sprent, J.1
Kishimoto, H.2
-
5
-
-
0029007485
-
Intrathymic and extrathymic clonal deletion of T cells
-
Sprent J, Webb SR. Intrathymic and extrathymic clonal deletion of T cells. Curr Opin Immunol 1995;7:196-205.
-
(1995)
Curr Opin Immunol
, vol.7
, pp. 196-205
-
-
Sprent, J.1
Webb, S.R.2
-
6
-
-
0030833571
-
T cell clonal anergy
-
Schwartz RH. T cell clonal anergy. Curr Opin Immunol 1997;9:351-357.
-
(1997)
Curr Opin Immunol
, vol.9
, pp. 351-357
-
-
Schwartz, R.H.1
-
7
-
-
0034141684
-
The third function of the thymus
-
Seddon B, Mason D. The third function of the thymus. Immunol Today 2000;21:95-99.
-
(2000)
Immunol Today
, vol.21
, pp. 95-99
-
-
Seddon, B.1
Mason, D.2
-
8
-
-
0034084162
-
Regulatory T cells in autoimmmunity
-
Shevach EM. Regulatory T cells in autoimmmunity. Annu Rev Immunol 2000;18:423-449.
-
(2000)
Annu Rev Immunol
, vol.18
, pp. 423-449
-
-
Shevach, E.M.1
-
9
-
-
0035554676
-
Regulatory T cells in the control of immune pathology
-
Maloy KJ, Powrie F. Regulatory T cells in the control of immune pathology. Nat Immunol 2001;2:816-822.
-
(2001)
Nat Immunol
, vol.2
, pp. 816-822
-
-
Maloy, K.J.1
Powrie, F.2
-
10
-
-
16844363097
-
A well adapted regulatory contrivance: Regulatory T cell development and the forkhead family transcription factor Foxp3
-
Fontenot JD, Rudensky AY. A well adapted regulatory contrivance: regulatory T cell development and the forkhead family transcription factor Foxp3. Nat Immunol 2005;6:331-337.
-
(2005)
Nat Immunol
, vol.6
, pp. 331-337
-
-
Fontenot, J.D.1
Rudensky, A.Y.2
-
11
-
-
2442484053
-
Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses
-
Sakaguchi S. Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses. Annu Rev Immunol 2004;22:531-562.
-
(2004)
Annu Rev Immunol
, vol.22
, pp. 531-562
-
-
Sakaguchi, S.1
-
12
-
-
0031647622
-
Immunological self-tolerance maintained by CD25+ CD4+ naturally anergic and suppresive T cells: Induction of autoimmune disease by breaking their anergic/suppressive state
-
Takahashi T, et al. Immunological self-tolerance maintained by CD25+ CD4+ naturally anergic and suppresive T cells: induction of autoimmune disease by breaking their anergic/suppressive state. Int Immunol 1998;10:1969-1980.
-
(1998)
Int Immunol
, vol.10
, pp. 1969-1980
-
-
Takahashi, T.1
-
13
-
-
0031821875
-
CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production
-
Thornton AM, Shevach EM. CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production. J Exp Med 1998;188:287-296.
-
(1998)
J Exp Med
, vol.188
, pp. 287-296
-
-
Thornton, A.M.1
Shevach, E.M.2
-
14
-
-
0029788211
-
Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation
-
Asano M, Toda M, Sakaguchi N, Sakaguchi S. Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation. J Exp Med 1996;184:387-396.
-
(1996)
J Exp Med
, vol.184
, pp. 387-396
-
-
Asano, M.1
Toda, M.2
Sakaguchi, N.3
Sakaguchi, S.4
-
15
-
-
0029150110
-
Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
-
Sakaguchi S, Sakaguchi N, Asano M, Itoh M, Toda M. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J Immunol 1995;155:1151-1164.
-
(1995)
J Immunol
, vol.155
, pp. 1151-1164
-
-
Sakaguchi, S.1
Sakaguchi, N.2
Asano, M.3
Itoh, M.4
Toda, M.5
-
16
-
-
0023720148
-
T cell antigen receptor genes and T cell recognition
-
Davis MM, Bjorkman PJ. T cell antigen receptor genes and T cell recognition. Nature 1988;334:395-401.
-
(1988)
Nature
, vol.334
, pp. 395-401
-
-
Davis, M.M.1
Bjorkman, P.J.2
-
17
-
-
0029037740
-
Expression of two T cell receptor alpha chains on the surface of normal murine T cells
-
Heath WR, Carbone FR, Bertolino P, Kelly J, Cose S, Miller JF. Expression of two T cell receptor alpha chains on the surface of normal murine T cells. Eur J Immunol 1995;25:1617-1623.
-
(1995)
Eur J Immunol
, vol.25
, pp. 1617-1623
-
-
Heath, W.R.1
Carbone, F.R.2
Bertolino, P.3
Kelly, J.4
Cose, S.5
Miller, J.F.6
-
18
-
-
0032538820
-
CD4(+) T cells prevent spontaneous experimental autoimmune encephalomyelitis in anti-myelin basic protein T cell receptor transgenic mice
-
Van de Keere F, Tonegawa S. CD4(+) T cells prevent spontaneous experimental autoimmune encephalomyelitis in anti-myelin basic protein T cell receptor transgenic mice. J Exp Med 1998;188:1875-1882.
-
(1998)
J Exp Med
, vol.188
, pp. 1875-1882
-
-
Van De Keere, F.1
Tonegawa, S.2
-
19
-
-
0032538918
-
Regulatory CD4(+) T cells expressing endogenous T cell receptor chains protect myelin basic protein-specific transgenic mice from spontaneous autoimmune encephalomyelitis
-
Olivares-Villagomez D, Wang Y, Lafaille JJ. Regulatory CD4(+) T cells expressing endogenous T cell receptor chains protect myelin basic protein-specific transgenic mice from spontaneous autoimmune encephalomyelitis. J Exp Med 1998;188:1883-1894.
-
(1998)
J Exp Med
, vol.188
, pp. 1883-1894
-
-
Olivares-Villagomez, D.1
Wang, Y.2
Lafaille, J.J.3
-
20
-
-
0037062420
-
Specificity requirements for selection and effector functions of CD25+4+ regulatory T cells in anti-myelin basic protein T cell receptor transgenic mice
-
USA
-
Hori S, Haury M, Coutinho A, Demengeot J. Specificity requirements for selection and effector functions of CD25+4+ regulatory T cells in anti-myelin basic protein T cell receptor transgenic mice. Proc Natl Acad Sci USA 2002;99:8213-8218.
-
(2002)
Proc Natl Acad Sci
, vol.99
, pp. 8213-8218
-
-
Hori, S.1
Haury, M.2
Coutinho, A.3
Demengeot, J.4
-
21
-
-
0033136302
-
Thymus and autoimmunity: Production of CD25+ CD4+ naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance
-
Itoh M, et al. Thymus and autoimmunity: production of CD25+ CD4+ naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance. J Immunol 1999;162:5317-5326.
-
(1999)
J Immunol
, vol.162
, pp. 5317-5326
-
-
Itoh, M.1
-
22
-
-
0035320679
-
Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide
-
Jordan MS, et al. Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide. Nat Immunol 2001;2:301-306.
-
(2001)
Nat Immunol
, vol.2
, pp. 301-306
-
-
Jordan, M.S.1
-
23
-
-
0033988289
-
Anergy and suppression regulate CD4(+) T cell responses to a self peptide
-
Jordan MS, Riley MP, von Boehmer H, Caton AJ. Anergy and suppression regulate CD4(+) T cell responses to a self peptide. Eur J Immunol 2000;30:136-144.
-
(2000)
Eur J Immunol
, vol.30
, pp. 136-144
-
-
Jordan, M.S.1
Riley, M.P.2
Von Boehmer, H.3
Caton, A.J.4
-
25
-
-
0043244867
-
Antigen-dependent proliferation of CD4+ CD25+ regulatory T cells in vivo
-
Walker LS, Chodos A, Eggena M, Dooms H, Abbas AK. Antigen-dependent proliferation of CD4+ CD25+ regulatory T cells in vivo. J Exp Med 2003;198:249-258.
-
(2003)
J Exp Med
, vol.198
, pp. 249-258
-
-
Walker, L.S.1
Chodos, A.2
Eggena, M.3
Dooms, H.4
Abbas, A.K.5
-
26
-
-
0036568942
-
Generation of CD4(+) CD25(+) regulatory T cells from autoreactive T cells simultaneously with their negative selection in the thymus and from nonautoreactive T cells by endogenous TCR expression
-
Kawahata K, et al. Generation of CD4(+) CD25(+) regulatory T cells from autoreactive T cells simultaneously with their negative selection in the thymus and from nonautoreactive T cells by endogenous TCR expression. J Immunol 2002;168:4399-4405.
-
(2002)
J Immunol
, vol.168
, pp. 4399-4405
-
-
Kawahata, K.1
-
27
-
-
15244354286
-
Regulatory T cell lineage specification by the forkhead transcription factor foxp3
-
Fontenot JD, Rasmussen JP, Williams LM, Dooley JL, Farr AG, Rudensky AY. Regulatory T cell lineage specification by the forkhead transcription factor foxp3. Immunity 2005;22:329-341.
-
(2005)
Immunity
, vol.22
, pp. 329-341
-
-
Fontenot, J.D.1
Rasmussen, J.P.2
Williams, L.M.3
Dooley, J.L.4
Farr, A.G.5
Rudensky, A.Y.6
-
28
-
-
0025362668
-
β-globin dominant control region interacts differently with distal and proximal promoter elements
-
Antoniou M, Grosveld F. β-globin dominant control region interacts differently with distal and proximal promoter elements. Genes Dev 1990;4:1007-1013.
-
(1990)
Genes Dev
, vol.4
, pp. 1007-1013
-
-
Antoniou, M.1
Grosveld, F.2
-
29
-
-
0026503761
-
Tolerance and MHC restriction in transgenic mice expressing a MHC class I gene in erythroid cells
-
Yeoman H, Mellor AL. Tolerance and MHC restriction in transgenic mice expressing a MHC class I gene in erythroid cells. Int Immunol 1992;4:59-65.
-
(1992)
Int Immunol
, vol.4
, pp. 59-65
-
-
Yeoman, H.1
Mellor, A.L.2
-
30
-
-
0027499946
-
In vivo analysis of the murine β-myosin heavy chain gene promoter
-
Rindt H, Gulick J, Knotts S, Neumann J, Robbins J. In vivo analysis of the murine β-myosin heavy chain gene promoter. J Biol Chem 1993;268:5332-5338.
-
(1993)
J Biol Chem
, vol.268
, pp. 5332-5338
-
-
Rindt, H.1
Gulick, J.2
Knotts, S.3
Neumann, J.4
Robbins, J.5
-
31
-
-
2942724435
-
CD4+ CD25+ regulatory T cell repertoire formation in response to varying expression of a neo-self-antigen
-
Lerman MA, Larkin J, Cozzo C, Jordan MS, Caton AJ. CD4+ CD25+ regulatory T cell repertoire formation in response to varying expression of a neo-self-antigen. J Immunol 2004;173:236-244.
-
(2004)
J Immunol
, vol.173
, pp. 236-244
-
-
Lerman, M.A.1
Larkin, J.2
Cozzo, C.3
Jordan, M.S.4
Caton, A.J.5
-
32
-
-
9244244736
-
Number of T reg cells that differentiate does not increase upon encounter of agonist ligand on thymic epithelial cells
-
van Santen HM, Benoist C, Mathis D. Number of T reg cells that differentiate does not increase upon encounter of agonist ligand on thymic epithelial cells. J Exp Med 2004;200:1221-1230.
-
(2004)
J Exp Med
, vol.200
, pp. 1221-1230
-
-
Van Santen, H.M.1
Benoist, C.2
Mathis, D.3
-
33
-
-
0028359368
-
Thymic selection of CD8+ single positive cells with a class II major histocompatibility complex-restricted receptor
-
Kirberg J, Baron A, Jakob S, Rolink A, Karjalainen K, von Boehmer H. Thymic selection of CD8+ single positive cells with a class II major histocompatibility complex-restricted receptor. J Exp Med 1994;180:25-34.
-
(1994)
J Exp Med
, vol.180
, pp. 25-34
-
-
Kirberg, J.1
Baron, A.2
Jakob, S.3
Rolink, A.4
Karjalainen, K.5
Von Boehmer, H.6
-
34
-
-
0034327169
-
Graded deletion and virus-induced activation of autoreactive CD4(+) T cells
-
Riley MP, Cerasoli DM, Jordan MS, Petrone AL, Shih FF, Caton AJ. Graded deletion and virus-induced activation of autoreactive CD4(+) T cells. J Immunol 2000;165:4870-4876.
-
(2000)
J Immunol
, vol.165
, pp. 4870-4876
-
-
Riley, M.P.1
Cerasoli, D.M.2
Jordan, M.S.3
Petrone, A.L.4
Shih, F.F.5
Caton, A.J.6
-
35
-
-
0029659049
-
Evidence for a thymus-dependent form of tolerance that is not based on elimination or anergy of reactive T cells
-
Le Douarin N, et al. Evidence for a thymus-dependent form of tolerance that is not based on elimination or anergy of reactive T cells. Immunol Rev 1996;149:35-53.
-
(1996)
Immunol Rev
, vol.149
, pp. 35-53
-
-
Le Douarin, N.1
-
36
-
-
0035920510
-
Major histocompatibility complex class II-positive cortical epithelium mediates the selection of CD4(+)25(+) immunoregulatory T cells
-
Bensinger SJ, Bandeira A, Jordan MS, Caton AJ, Laufer TM. Major histocompatibility complex class II-positive cortical epithelium mediates the selection of CD4(+)25(+) immunoregulatory T cells. J Exp Med 2001;194:427-438.
-
(2001)
J Exp Med
, vol.194
, pp. 427-438
-
-
Bensinger, S.J.1
Bandeira, A.2
Jordan, M.S.3
Caton, A.J.4
Laufer, T.M.5
-
37
-
-
0037112047
-
Projection of an immunological self shadow within the thymus by the aire protein
-
Anderson MS, et al. Projection of an immunological self shadow within the thymus by the aire protein. Science 2002;298:1395-1401.
-
(2002)
Science
, vol.298
, pp. 1395-1401
-
-
Anderson, M.S.1
-
38
-
-
0035171545
-
Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self
-
Derbinski J, Schulte A, Kyewski B, Klein L. Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self. Nat Immunol 2001;2:1032-1039.
-
(2001)
Nat Immunol
, vol.2
, pp. 1032-1039
-
-
Derbinski, J.1
Schulte, A.2
Kyewski, B.3
Klein, L.4
-
39
-
-
0037383758
-
Aire regulates negative selection of organ-specific T cells
-
Liston A, Lesage S, Wilson J, Peltonen L, Goodnow CC. Aire regulates negative selection of organ-specific T cells. Nat Immunol 2003;4:350-354.
-
(2003)
Nat Immunol
, vol.4
, pp. 350-354
-
-
Liston, A.1
Lesage, S.2
Wilson, J.3
Peltonen, L.4
Goodnow, C.C.5
-
40
-
-
7244227646
-
Gene dosage - Limiting role of aire in thymic expression, clonal deletion, and organ-specific autoimmunity
-
Liston A, et al. Gene dosage - limiting role of aire in thymic expression, clonal deletion, and organ-specific autoimmunity. J Exp Med 2004;200:1015-1026.
-
(2004)
J Exp Med
, vol.200
, pp. 1015-1026
-
-
Liston, A.1
-
41
-
-
0028238668
-
Specificity and flexibility in thymic selection
-
Jameson SC, Hogquist KA, Bevan MJ. Specificity and flexibility in thymic selection. Nature 1994;369:750-752.
-
(1994)
Nature
, vol.369
, pp. 750-752
-
-
Jameson, S.C.1
Hogquist, K.A.2
Bevan, M.J.3
-
42
-
-
0344585521
-
Cutting edge: Self-peptides drive the peripheral expansion of CD4+CD25+ regulatory T cells
-
Cozzo C, Larkin J, Caton AJ. Cutting edge: self-peptides drive the peripheral expansion of CD4+CD25+ regulatory T cells. J Immunol 2003;171:5678-5682.
-
(2003)
J Immunol
, vol.171
, pp. 5678-5682
-
-
Cozzo, C.1
Larkin, J.2
Caton, A.J.3
|