Phyto-chemical and pharmacological applications of Berberis aristata

Fitoterapia

Volumn 83, Issue 5, 2012, Pages 817-830

  Potdar, Dipti ^a   Hirwani, R R ^a   Dhulap, Sivakami ^a  

^a CSIR Unit for Research and Development of Information Products Jopasana   (India)

Author keywords

Anti diabetic; Anti microbial; Ayurveda; Berberine; Berberis aristata; Tree turmeric

Indexed keywords

ANALGESIC AGENT; ANTIBIOTIC AGENT; ANTIDIABETIC AGENT; ANTIFUNGAL AGENT; ANTIINFLAMMATORY AGENT; ANTILIPEMIC AGENT; ANTINEOPLASTIC AGENT; ANTIPYRETIC AGENT; ANTIRETROVIRUS AGENT; ANTIRHEUMATIC AGENT; ANTIVIRUS AGENT; BERBERIS ARISTATA EXTRACT; CARDIOTONIC AGENT; DERMATOLOGICAL AGENT; HERBACEOUS AGENT; IMMUNOSUPPRESSIVE AGENT; PLANT EXTRACT; UNCLASSIFIED DRUG;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ALOPECIA; ALZHEIMER DISEASE; ANALGESIC ACTIVITY; ANTIBACTERIAL ACTIVITY; ANTIDIABETIC ACTIVITY; ANTIFUNGAL ACTIVITY; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ANTIPYRETIC ACTIVITY; ANTIVIRAL ACTIVITY; ARTHRALGIA; BACTERIAL INFECTION; BERBERIS; BERBERIS AETNENSIS; BERBERIS ARISTATA; BERBERIS ASIATICA; BERBERIS BUXIFOLIA; BERBERIS CHILENSIS; BERBERIS CRATAEGINA; BERBERIS CROATICA; BERBERIS DARWINII; BERBERIS HETEROPHYLLA; BERBERIS HISPANICA; BERBERIS HOLSTII; BERBERIS INTEGERRIMA; BERBERIS KOREANA; BERBERIS LYCEUM; BERBERIS MICROPHYLLA; BERBERIS MUCROFOLIA; BERBERIS THUNBERGII; BERBERIS VALDIVIANA; BERBERIS VULGARIS; BLEEDING; CHOLERA; COUGHING; DIABETES MELLITUS; DIARRHEA; EAR INFECTION; ETHNOBOTANY; EYE DISEASE; EYE INFECTION; FEVER; GYNECOLOGIC DISEASE; HEART DISEASE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; JAUNDICE; LIVER CARCINOGENESIS; LIVER DISEASE; LIVER FIBROSIS; LIVER PROTECTION; LYMPHADENOPATHY; MALARIA; MENOPAUSAL SYNDROME; MENORRHAGIA; METABOLIC DISORDER; MOUTH DISEASE; NONHUMAN; OSTEOPOROSIS; PARASITOSIS; PATENT; PHARMACOGNOSY; PHYTOCHEMISTRY; PLANT LEAF; PLANT ROOT; PNEUMONIA; PRIORITY JOURNAL; REVIEW; RHEUMATIC DISEASE; SEXUALLY TRANSMITTED DISEASE; SKIN DISEASE; STOMACH PAIN; URINARY TRACT INFECTION; WOUND;

BERBERIS; ETHNOBOTANY; HUMANS; MEDICINE, AYURVEDIC; PATENTS AS TOPIC; PHYTOTHERAPY; PLANT EXTRACTS;

BACTERIA (MICROORGANISMS); BERBERIDACEAE; BERBERIS ARISTATA; CHITRA; CURCUMA LONGA;

EID: 84861624678     PISSN: 0367326X     EISSN: 18736971     Source Type: Journal    
DOI: 10.1016/j.fitote.2012.04.012     Document Type: Review

References (131)

1. A.R. Joshi, and K. Joshi Ethnomedicinal plants used against skin diseases in some villages of Kali Gandaki, Bagmati and Tadi Likhu watersheds of Nepal Ethnobot Leafl 11 2007 235 246
2. G. Saraf, A. Mitra, Kumar Dinesh, S. Mukherjee, and A. Basu Role of nonconventional remedies in rural India Int J Pharm Lifesci 1 2010 141 159
3. H.S. Yogesh, V.M. Chandrashekhar, H.R. Katti, S. Ganapaty, H.L. Raghavendra, and G.K. Gowda Anti-osteoporotic activity of aqueous-methanol extract of Berberis aristata in ovariectomized rats J Ethnopharmacol 134 2011 334 338
4. M. Shahid, T. Rahim, A. Shahzad, Tajuddin, A. Latif, and T. Fatma Ethnobotanical studies on Berberis aristata D.C. root extracts Afr J Biotechnol 8 2009 556 563
5. Dr.Duke's Phytochemical and Ethnobotanical Database.
6. A. Meena, P. Bansal, and Sanjivkumar Plants - herbal wealth as a potential source of ayurvedic drugs Asian J Tradit Med 4 2009 152 170
7. S.C. Sati, and S. Joshi Aspects of antifungal potential of ethnobotanically known medicinal plants Res J Med Plant 5 2011 377 391
8. P.C. Phondani, R.K. Maikhuri, L.S. Rawat, N.A. Farooquee, C.P. Kala, and S.C.R. Vishvakarma Ethnobotanical uses of plants among the Bhotiya tribal communities of Niti Valley in Central Himalaya, India Ethnobotany Res Appl 8 2010 233 244
9. P.K. Sharma, N.S. Chauhan, and Brij Lal Studies on plant associated indigenous knowledge among the Malanis of Kullu district, Himachal pradesh Indian J Tradit Knowl 4 2005 403 408
10. J.K. Tiwari, R. Ballabha, and P. Tiwari Ethnopaediatrics in Garhwal Himalaya, Uttarakhand, India (Psychomed Med), New York Sci J 3 2010 123 126
11. K.P. Acharya, and M.B. Rokaya Ethnobotanical survey of medicinal plants traded in the streets of Kathmandu valley Sci World 3 2005 44 48
12. R.M. Kunwar, and N. Adhikari Ethnomedicine of Dolpa district, Nepal: the plants, their vernacular names and uses Lyonia 8 2005 43 49
13. D.R. Chhetri, P. Parajuli, and G.C. Subba Antidiabetic plants used by Sikkim and Darjeeling Himalayan tribes, India J Ethnopharmacol 99 2005 199 202
14. G. Blasko, N. Murugesan, A.J. Freyer, M. Shamma, A. Ansari, and Atta-ur-Rahman Karachine: an unusual protoberberine alkaloid J Am Chem Soc 104 1982 2039 2041
15. Atta-ur-Rahman, and A. Ansari Alkaloids of Berberis aristata - isolation of aromoline and oxyberberine J Chem Soc Pak 5 1983 283 284
16. R. Sivakumar, and A.G.R. Nair Polyphenolic constituents of the flowers of Berberis aristata J Indian Chem Soc 68 1991 531 532
17. S. Saied, S. Batool, and S. Naz Phytochemical studies of Berberis aristata J Basic Appl Sci 3 2007 1 3
18. G. Blasko, N. Murugesan, A.J. Freyer, M. Shamma, A. Ansari, and Atta-ur-Rahman Taxilamine, a pseudobenzylisoquinoline alkaloid Heterocycles 19 1982 257 259
19. K.K. Chakravarti, D.C. Dhar, and S. Siddiqui Alkaloidal constituents of the bark of Berberis aristata J Sci Ind Res 9 7 1950 161 164
20. K.K. Chakravarti Alkaloidal constituents of the bark of Berberis aristata J Sci Ind Res 9 1950 306
21. D. Katiyar, R. Singh, S. Singh, D. Singh, and V. Singh Isolation and characterization of n-docosane from heartwood of Berberis aristata Int J Pharm Sci Res 2 2011 331 335
22. S.K. Chauhan, B.P. Singh, R. Bhattacharya, and S. Agrawal HPTLC and spectrophotometric determination of berberine from Berberis aristata D.C Indian Drugs 37 2000 305 308
23. H.C. Andola, R.S. Rawal, M.S. Rawat, I.D. Bhatt, and W. Purohit Analysis of berberine content using HPTLC fingerprinting of root and bark of three Himalayan Berberis species Asian J Biotechnol 2 2010 239 245
24. A.K. Meena, P. Bansal, Sanjivkumar, M.M. Rao, and V.K. Garg Estimation of heavy metals in commonly used medicinal plants: a market basket survey Environ Monit Assess 170 2010 657 660
25. L. Upadhyay, A. Mehrotra, A.K. Srivastava, N.P. Rai, and K. Tripathi An experimental study of some indigenous drugs with special reference to hydraulic permeability Indian J Exp Biol 39 2001 1308 1310
26. Y.R. Sohni, and R.M. Bhatt Activity of a crude extract formulation in experimental hepatic amoebiasis and in immunomodulation studies J Ethnopharmacol 54 1996 119 124
27. A.H. Gilani, and K.H. Janbaz Prevention of acetaminophen-induced liver damage by Berberis aristata leaves Biochem Soc Trans 20 1992 347S
28. A.M. Patel, S.S. Darade, P.G. Jain, and A.M. Kandalkar Formulation and evaluation of proprietary polyherbal formulation for their hepatoprotective activity Int J Pharm Tech Res 2 2010 305 309
29. A.H. Gilani, and K.H. Janbaz Preventive and curative effects of Berberis aristata fruit extract on paracetamol- and CCl4-induced hepatotoxicity Phytother Res 9 1995 489 494
30. W. Fang, Z. Hong-Yi, and Z. Gang Inhibitory effects of berberine on ion channels of rat hepatocytes World J Gastroenterol 10 2004 2842 2845
31. Tsai Pi-Lo, and Tsai Tung-Hu Hepatobiliary excretion of berberine Drug Metab Dispos 32 2004 405 412
32. Y. Feng, and K. Cheung Chinese medicines as a resource for liver fibrosis treatment Chin Med 4 2009 16
33. P.V. Joshi, A.A. Shirkhedkar, K. Prakash, and V.L. Maheshwari Antidiarrheal activity, chemical and toxicity profile of Berberis aristata Pharm Biol 49 2011 94 100
34. R.B. Sack, and J.L. Froehlich Berberine inhibits intestinal secretory response of Vibrio cholerae and Escherichia coli enterotoxins Infect Immun 35 1982 471 475
35. M. Sabir, M.H. Akhter, and N.K. Bhide Antagonism of cholera toxin by berberine in the intestinal tract of adult rats Indian J Med Res 65 1977 305 313
36. Y.B. Tripathi, and S.D. Shukla Berberis aristata inhibits PAF induced aggregation of rabbit platelets Phytother Res 10 1996 628 630
37. B.H. Shah, Z. Nawaz, S.A. Saeed, and A.H. Gilani Agonist-dependent differential effects of berberine in human platelet aggregation Phytother Res 12 Suppl. 1 1998 S60 S62 Second International Symposium On Natural Drugs, 1997
38. K.K.M. Ahmed, M.Y. Khan, and B.G. Shivananda Cardiovascular diseases and role of medicinal plants as a re-emerging health aid Pharmacogn Rev 3 2009 8 14
39. A.H. Gilani, K.H. Janbaz, N. Aziz, M.J. Herzig, M.M. Kazmi, and M.I. Choudhary Possible mechanism of selective inotropic activity of the n-butanolic fraction from Berberis aristata fruit Gen Pharmacol 33 1999 407 414
40. F.A. Razzaq, R.A. Khan, R. Alam, Z. Feroz, and A. Syeda Effect of Berberis aristata on lipid profile and coagulation parameters Afr J Pharm Pharmacol 5 2011 943 947
41. N. Upwar, R. Patel, N. Waseem, and N. Mahobia Pharmacognostic evaluation of stem of Berberis aristata D.C. Pharmacogn J 2 2010 5 9
42. B.C. Semwal, K. Shah, N.S. Chauhan, R. Badhe, and K. Divakar Anti-diabetic activity of stem bark of Berberis aristata D.C. in alloxan induced diabetic rats Internet J Pharmacol 6 2008
43. J. Singh, and P. Kakkar Anti-hyperglycaemic and antioxidant effect of Berberis aristata root extract and its role in regulating carbohydrate metabolism in diabetic rats J Ethnopharmacol 123 2009 22 26
44. R. Sundaram, M.V. Venkataranganna, S. Gopumadhavan, and S.K. Mitra Interaction of a herbomineral preparation D-400, with oral hypoglycaemic drugs J Ethnopharmacol 55 1996 55 61
45. N. Upwar, R. Patel, N. Waseem, and N. KumarMahobia Hypoglycaemic effect of methanolic extract of Berberis aristata D.C. stem on normal and streptozotocin induced diabetic rats International Journal of Pharmacy and Pharm Sci 3 1 2011 222 224
46. R. Steriti Berberine for diabetes mellitus type 2 Nat Med J 2 2010
47. R. Chakrabarti, B. Singh, N. Prakrith, N. Varghese, L. Vanchhawng, and H. Shihabudeen Dipeptidyl peptidase-IV inhibitory activity of Berberis aristata J Nat Prod (Gorakhpur, India) 4 2011 158 163
48. S. Das, M.K. Das, P.M. Mazumder, S. Das, and S.P. Basu Cytotoxic activity of methanolic extract of Berberis aristata D.C. on colon cancer Glob J Pharmacol 3 2009 137 140
49. K.V. Anis, N.V. Rajeshkumar, and R. Kuttan Inhibition of chemical carcinogenesis by berberine in rats and mice J Pharm Pharmacol 53 2001 763 768
50. S.B. Muralimanoharan, and A.B. Kunnumakkara Butanol fraction containing berberine or related compound from Nexrutine® inhibits NFκB signaling and induces apoptosis in prostate cancer cells Prostate 69 2009 494 504
51. S.J. Liu, Y.M. Sun, and D.F. Tian Downregulated NM23-H1 expression is associated with intracranial invasion of nasopharyngeal carcinoma Br J Cancer 98 2008 363 369
52. M.S. Choi, D.Y. Yuk, J.H. Oh, H.Y. Jung, S.B. Han, and D.C. Moon Berberine inhibits human neuroblastoma cell growth through induction of p53-dependent apoptosis Anticancer Res 28 2008 3777 3784
53. S. Adikay, B. Koganti, Prasad, and KVSRG Effect of decoction of root bark of Berberis aristata against cisplatin induced nephrotoxicity in rats Int J Pharm Pharm Sci 2 2010 51 56
54. S.K. Gupta, R. Agarwal, S. Srivastava, P. Agarwal, S.S. Agrawal, and R. Saxena The anti-inflammatory effects of Curcuma longa and Berberis aristata in endotoxin-induced uveitis in rabbits Invest Ophthalmol Vis Sci 49 2008 4036 4040
55. A. Latif, A. Razique, R.R. Sukul, and N. Siddiqui Anti-inflammatory and anti-histaminic study of a Unani eye drop formulation Ophthalmol Eye Dis 2 2010 17 22
56. Berberine Altern Med Rev 5 2000 175 177
57. M. Singha, S. Srivastava, and A.K.S. Rawata Antimicrobial activities of Indian Berberis species Fitoterapia 78 2007 574 576
58. F. Malik, T. Mirza, H. Riaz, A. Hameed, and S. Hussain Biological screening of seventeen medicinal plants used in the traditional systems of medicine in Pakistan for antimicrobial activities Afr J Pharm Pharmacol 4 2010 335 340
59. P. Deshmukh, P. Gupta, and R. Shankar In vitro and in vivo efficacy of a herbal formulation against skin infections J Pure Appl Microbiol 3 2009 199 204
60. S.F.H. Zaidi, K. Yamada, M. Kadowaki, U. Khan, and T. Sugiyama Bactericidal activity of medicinal plants, employed for the treatment of gastrointestinal ailments, against Helicobacter pylori J Ethnopharmacol 121 2009 286 291
61. S.A. Soffar, D.M. Metwali, S.S. Abdel-Aziz, H.S. el-Wakil, and G.A. Saad Evaluation of the effect of a plant alkaloid (berberine derived from Berberis aristata) on Trichomonas vaginalis - in vitro J Egypt Soc Parasitol 31 2001 893 904
62. B. Singh, J.S. Srivastava, R.L. Khosa, and U.P. Singh Individual and combined effects of berberine and santonin on spore germination of some fungi Folia Microbiol (Praha) 46 2001 137 142
63. A. Mathur, R. Singh, S. Yousuf, A. Bhardwaj, S.K. Verma, and P. Babu Antifungal activity of some plant extracts against clinical pathogens Adv Appl Sci Res 2 2011 260 264
64. R.S. Sharma, V. Mishra, R. Singh, N. Seth, and C.R. Babu Antifungal activity of some Himalayan medicinal plants and cultivated ornamental species Fitoterapia 79 2008 589 591
65. A.K. Ghosh, F.K. Bhattacharyya, and D.K. Ghosh Leishmania donovani: amastigote inhibition and mode of action of berberine Exp Parasitol 60 1985 404 413
66. P. Sharma, and G. Singh A review of plant species used to treat conjunctivitis Phytother Res 16 2002 1 22
67. K.S. Dhiman, K. Dhiman, S. Puri, and D. Ahuja A comprehensive review of cataract (kaphaja linganasha) and its surgical treatment in ayurvedic literature Ayu 31 2010 93 100
68. S.K.R. Premnath, and S.N. Yoganarasimhan Evaluation of antibacterial activity of Elanir kujambu - an ayurvedic eye formulation Indian J Tradit Knowl 8 2009 272 274
69. S.K. Kulkarni, and A. Dhir On the mechanism of antidepressant-like action of berberine chloride Eur J Pharmacol 589 2008 163 172
70. S.K. Kulkarni, and A. Dhir Berberine: a plant alkaloid with therapeutic potential for central nervous system disorders Phytother Res 24 2010 317 324
71. R.H. Singh, and B.N. Sinha Clinical and psychobiological studies on the effect of an indigenous compound Rasayana drug in apparently normal aged persons J Res Indian Med Yoga Homoeopathy 13 1978 8 14
72. S. Mishra, R.R. Dwivedi, B. Ravishankar, and B.K. Ashok An experimental study on hypolipidemic effect of some selected Ruksha guna drugs Ayu 30 2009 205 210
73. T.K. Biswas, and B. Mukherjee Plant medicines of Indian origin for wound healing activity: a review Int J Low Extrem Wounds 2 2003 25 39
74. R.K. Mamgain Acne vulgaris and its treatment by indigenous drugs SK-34 (Purim) and SK-235 (Clarina) Antiseptic 97 2000 76 78
75. S.K. Mehta Clinical trial of Pilex tablets and ointment on the patients of haemorrhoids Probe 13 1974 121 127
76. B.P. Varandani Indigenous therapy for piles Indian Pract 22 1969 545 547
77. P. Bafna, and S. Bodhankar Gastrointestinal effects of Mebarid®, an ayurvedic formulation, in experimental animals J Ethnopharmacol 86 2003 173 176
78. K. Seema, M.R. Rao, I.B. Reddy, and V.R. Rao Study on radical scavenging activity and analysis of bioactive compounds in selected Indian medicinal plants Biosci Biotechnol Res Asia 7 2010 913 918
79. D.K. Tewary, A. Bhardwaj, and A. Shanker Pesticidal activities in five medicinal plants collected from mid hills of western Himalayas Ind Crops Prod 22 3 2005 241 247
80. N. Chand, F.R. Durrani, M.S. Qureshi, and Z. Durrani Role of Berberis lycium in reducing serum cholesterol in broilers Asian Australas J Anim Sci 20 4 2007 563 568
81. A. Asif, G. Kakub, S. Mehmood, R. Khunum, and M. Gulfraz Wound healing activity of root extracts of Berberis lyceum Royle in rats Phytother Res 21 6 2007 589 591
82. M. Gulfraz, S. Mehmood, A. Ahmad, N. Fatima, Z. Praveen, and E.M. Williamson Comparison of the antidiabetic activity of Berberis lyceum root extract and berberine in alloxan-induced diabetic rats Phytother Res 22 9 2008 1208 1212
83. M. Khan, B. Giessrigl, C. Vonach, S. Madlener, S. Prinz, and I. Herbaceck Berberine and a Berberis lycium extract inactivate Cdc25A and induce alpha-tubulin acetylation that correlate with HL-60 cell cycle inhibition and apoptosis Mutat Res Fundam Mol Mech Mutagenesis 683 1-2 2010 123 130
84. I. Bukhari, M. Hassan, F.M. Abbasi, G. Mujtaba, N. Mahmood, and Noshin A study on comparative pharmacological efficacy of Berberis lycium and penicillin G Afr J Microbiol Res 5 6 2011 725 727
85. N. Chand, F.R. Durrani, S. Ahmad, and A. Khan Immunomodulatory and hepatoprotective role of feed-added Berberis lycium in broiler chicks J Sci Food Agric 91 10 2011 1737 1745
86. F. Shamsa, A. Ahmadiani, and R. Khosrokhavar Antihistaminic and anticholinergic activity of barberry fruit (Berberis vulgaris) in the guineapig ileum J Ethnopharmacol 64 2 1999 161 166
87. N. Ivanovska, and S. Philipov Study on the anti-inflammatory action of Berberis vulgaris root extract, alkaloid fractions and pure alkaloids Int J Immunopharmacol 18 10 1996 553 561
88. D.A. Azizullah, and M.A. Mirza Sensitivity of Staphylococcus against antibiotics, homeopathic drugs and antibacterial compounds Proc Natl Conf Biol 1 2002 219 222
89. Z. Fatehi-Hassanabad, M. Jafarzadeh, A. Tarhini, and M. Fatehi The antihypertensive and vasodilator effects of aqueous extract from Berberis vulgaris fruit on hypertensive rats Phytother Res 19 3 2005 222 225
90. M. Fatehi, T.M. Saleh, Z. Fatehi-Hassanabad, K. Farrokhfal, M. Jafarzadeh, and S. Davodi A pharmacological study on Berberis vulgaris fruit extract J Ethnopharmacol 102 1 2005 46 52
91. G. Ahmad, F.H. Zahra, F. Mohammad, and F. Khadijeh Study of cardiovascular effects of Berberis vulgaris (B.V.) aqueous extract on hypertensive rats and their probable mechanisms Hypertension 46 4 2005 914-914
92. G. Motalleb, P. Hanachi, A. Rahmat, and F. Othman Alpha-fetoprotein gene expression and glutathione S-transferase activity of hepatocytes during hepatocarcinogenesis in rats treated with Berberis vulgaris fruit extract FEBS J 273 1 2006 223
93. P. Hanachi, F. Yakhob, F. Othman, and G. Motalleb In vivo study of Berberis vulgaris on hepatocarcinogenesis rats FEBS J 273 1 2006 295-295
94. M.S. Arayne, N. Sultana, and S.S. Baradur The Berberis story: Berberis vulgaris in therapeutics Pak J Pharm Sci 20 1 2007 83 92
95. A. Elkhateeb, K. Yamada, K. Takahashi, H. Matsuura, M. Yamasaki, and Y. Maede Anti-babesial compounds from Berberis vulgaris Nat Prod Commun 2 2 2007 173 176
96. H. Tomosaka, H. Chai, Y.W. Chin, A.A. Salim, W.J. Keller, and A.D. Kinghorn AGFD 132-antioxidants from Berberis vulgaris (Barberry) Abstracts of Papers of the American Chemical Society Meeting Abstract: 132-AGFD 234 2007
97. M. Imanshahidi, and H. Hosseinzadeh Pharmacological and therapeutic effects of Berberis vulgaris and its active constituent, berberine Phytother Res 22 8 2008 999 1012
98. H. Tomosaka, Y.W. Chin, A.A. Salim, W.J. Keller, J. William, and H. Chai Antioxidant and cytoprotective compounds from Berberis vulgaris (barberry) Phytother Res 22 7 2008 979 981
99. M.Z. Koncic, D. Kremer, K. Karlovic, and I. Kosalec Evaluation of antioxidant activities and phenolic content of Berberis vulgaris L. and Berberis croatica Horvat Food Chem Toxicol 48 8-9 2010 2176 2180
100. S. Bashir, A.H. Gilani, A.A. Siddiqui, S. Pervez, S.R. Khan, and N.J. Sarfaraz Berberis vulgaris root bark extract prevents hyperoxaluria induced urolithiasis in rats Phytother Res 24 8 2010 1250 1255
101. Z. Rajaei, M.A.R. Hajzadeh, S. Shafiee, A. Alavinejhad, and S. Samarghandian Effect of barberry fruit (Berberis vulgaris) on serum glucose and lipids in streptozotocin-diabetic rats Clin Biochem 44 13 2011 S334-S334
102. H. Elyas, and Razieh Evaluation of anticoagulant properties of Artemisia dracunculus, Punica granatum and Berberis vulgaris in rat Clin Biochem 44 13 2011 S179 S180
103. M. Minaiyan, A. Ghannadi, P. Mahzouni, and E. Jaffari-Shirazi Comparative study of Berberis vulgaris fruit extract and berberine chloride effects on acetic acid-induced colitis in rats Iran J Pharm Res 10 1 2011 97 104
104. S.K. Srivastava, A.K.S. Rawat, and S. Mehrotra Pharmacognostic evaluation of the root of Berberis asiatica Pharm Biol 42 6 2004 467 473
105. H.C. Andola, R.S. Rawal, and I.D. Bhatt Antioxidants in fruits and roots of Berberis asiatica Rox. ex. DC.: a highly valued Himalayan plant Natl Acad Sci Lett India 31 11 2008 11 12 337-340
106. R. Musumeci, A. Speciale, R. Costanzo, A. Annino, S. Ragusa, and A. Rapisarda Berberis aetnensis C. Presl. extracts: antimicrobial properties and interaction with ciprofloxacin Int J Antimicrob Agents 22 1 2003 48 53
107. A. Campisi, A. Speciale, R. Acquaviva, G. Raciti, I. Barbagallo, and S. Puglisi Effect of Berberis aetnensis C. Presl extract on tissue transglutaminase expression in primary astroglial cell cultures exposed to glutamate Int J Antimicrob Agents 29 2 2007 S202-S202
108. L. Iauk, R. Costanzo, F. Caccamo, A. Rapisarda, R. Musumeci, and I. Milazzo Activity of Berberis aetnensis root extracts on Candida strains Fitoterapia 78 2 2007 159 161
109. K.Y. Yoo, I.K. Hwang, J.D. Kim, I.J. Kang, J. Park, and J.S. Yi Antiinflammatory effect of the ethanol extract of Berberis koreana in a gerbil model of cerebral ischemia/reperfusion Phytother Res 22 11 2008 1527 1532
110. S.A. Qadir, M.C. Kwon, J.G. Han, J.H. Ha, H.S. Chung, and J. Ahn Effect of different extraction protocols on anticancer and antioxidant activities of Berberis koreana bark extracts J Biosci Bioeng 107 3 2009 331 338
111. K.H. Kim, S.U. Choi, S.K. Ha, S.Y. Kim, and K.R. Lee Biphenyls from Berberis koreana J Nat Prod 72 11 2009 2061 2064
112. K.H. Kim, S.U. Choi, and K.R. Lee Bioactivity-guided isolation of cytotoxic triterpenoids from the trunk of Berberis koreana Bioorg Med Chem Lett 20 6 2010 1944 1947
113. B.H. Kim, J. Lee, T. Shen, J.D. Kim, and J.Y. Cho Anti-inflammatory activity of hot water extract of Berberis koreana in lipopolysaccharide-induced macrophage-like cells J Med Plants Res 4 9 2010 745 752
114. K.H. Kim, S.U. Choi, and K.R. Lee Cytotoxic triterpenoids from Berberis koreana Planta Med 78 1 2012 86 89
115. M. Zovko, K. Sankovic, I. Kosalec, D. Kremer, K. Karlovic, and Z. Kalodera Free-radical scavenging capacity and antioxidant activity of Berberis croatica Horvat and B. vulgaris L Planta Med 74 9 2008 972-972
116. I. Kosalec, B. Gregurek, D. Kremer, M. Zovko, K. Sankovic, and K. Karlovic Croatian barberry (Berberis croatica Horvat): a new source of berberine-analysis and antimicrobial activity World J Microbiol Biotechnol 25 1 2009 145 150
117. J.R. Villinski, E.R. Dumas, H.B. Chai, J.M. Pezzuto, C.K. Angerhofer, and S. Gafner Antibacterial activity and alkaloid content of Berberis thunbergii, Berberis vulgaris and Hydrastis canadensis Pharm Biol 41 8 2003 551 557
118. A.R. Li, Y. Zhu, X.N. Li, and X.J. Tian Antimicrobial activity of four species of Berberidaceae Fitoterapia 78 5 2007 379 381
119. S.I. Pitta-Alvarez, F. Medina-Bolivar, M.A. Alvarez, A.A. Scambatto, and P.L. Marconi In vitro shoot culture and antimicrobial activity of Berberis buxifolia Lam In Vitro Cell Dev Biol Plant 44 6 2008 502 507
120. C. Albrecht, G. Pellarin, M.J. Rojas, I. Albesa, and A.J. Eraso Beneficial effect of Berberis buxifolia lam, Zizyphus mistol griseb and Prosopis alba extracts on oxidative stress induced by chloramphenicol Med B Aires 70 1 2010 65 70
121. J.L. Martinez, R. Torres, and M.A. Morales Hypotensive effect of O-methylisothalicberine, a bisbenzylisoquinoline alkaloid isolated from Berberis chilensis on normotensive rats Phytother Res 11 3 1997 246 248
122. C.K. Angerhofer, H. Guinaudeau, V. Wongpanich, J.M. Pezzuto, and G.A. Cordell Antiplasmodial and cytotoxic activity of natural bisbenzylisoquinoline alkaloids J Nat Prod 62 1 1999 59 66
123. E. Yesilada, and E. Kupeli Berberis crataegina DC. root exhibits potent anti-inflammatory, analgesic and febrifuge effects in mice and rats J Ethnopharmacol 79 2 2002 237 248
124. M.L. Freile, F. Giannini, G. Pucci, A. Sturniolo, L. Rodero, and O. Pucci Antimicrobial activity of aqueous extracts and of berberine isolated from Berberis heterophylla Fitoterapia 74 7-8 2003 702 705
125. A. Jamshidzadeh, and H. Niknahad Hepatoprotective activity of Berberis integerrima Bge extract in rats treated with CCl(4): in vitro and in vivo studies Toxicol Lett 164 2006 Special Issue: SI Pages: S310-S310
126. N. Fokialakisokialakis, E. Kalpoutzakis, B.L. Tekwani, S.I. Khan, M. Kobaisy, and A.L. Skaltsounis Evaluation of the antimalarial and antileishmanial activity of plants from the Greek island of Crete J Nat Med 61 1 2007 38 45
127. B. Ahmed, M.H. Masoodi, and S. Khan Pachycanthine: a new isoquinoline alkaloid and its antihepatotoxic activity from Berberis pachycantha Koehne Indian J Chem, Sect B 47 6 2008 945 951
128. N. Merghoub, L. Benbacer, S. Amzazi, H. Morjani, and E.l. Mzibri Mohamed Cytotoxic effect of some Moroccan medicinal plant extracts on human cervical cell lines J Med Plants Res 3 12 2009 1045 1050
129. A. Ruiz, I. Hermosin-Gutierrez, C. Mardones, C. Vergara, E. Herlitz, and M. Vega Polyphenols and antioxidant activity of Calafate (Berberis microphylla) fruits and other native berries from Southern Chile J Agric Food Chem 58 10 2010 6081 6089
130. C.P. Maliwichi-Nyirenda, L.L. Maliwichi, and M. Franco Medicinal uses of Berberis holstii Engl. (Berberidaceae) in Malawi, the only African endemic barberry J Med Plants Res 5 8 2011 1367 1373
131. S. Habtemariam The therapeutic potential of Berberis darwinii stem-bark: quantification of berberine and in vitro evidence for Alzheimer's disease therapy Nat Prod Commun 6 8 2011 1089 1090